Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and potency of chemicals

Journal of Applied Toxicology

Volumn 35, Issue 11, 2015, Pages 1318-1332

  Takenouchi, Osamu ^a   Fukui, Shiho ^b   Okamoto, Kenji ^b   Kurotani, Satoru ^c   Imai, Noriyasu ^c   Fujishiro, Miyuki ^d   Kyotani, Daiki ^d   Kato, Yoshinao ^e   Kasahara, Toshihiko ^f   Fujita, Masaharu ^f   Toyoda, Akemi ^g   Sekiya, Daisuke ^h   Watanabe, Shinichi ^h   Seto, Hirokazu ⁱ   Hirota, Morihiko ^j   Ashikaga, Takao ^j   Miyazawa, Masaaki ^a  

^a KAO CORPORATION   (Japan)

^b KANEBO LTD   (Japan)

^c Cutaneous Research Section   (Japan)

^d NIKKOL Group Cosmos Technical Center Co   (Japan)

^e Nippon Menard Cosmetic Co Ltd   (Japan)

^f FUJIFILM CORPORATION   (Japan)

^g POLA CHEMICAL INDUSTRIES INC   (Japan)

^h LION CORPORATION   (Japan)

ⁱ P and G Japan KK   (Japan)

^j SHISEIDO RESEARCH CENTER   (Japan)

more..

Author keywords

DEREK; DPRA; H CLAT; In vitro test; Integrated testing strategy; Sequential testing strategy; Skin sensitization; Test battery

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 1 NAPHTHOL; 1,4 BENZOQUINONE; 2 AMINOPHENOL; 2 MERCAPTOBENZOTHIAZOLE; 2,5 DIAMINOTOLUENE; 4 CHLOROANILINE; ALDEHYDE; ALPHA TOCOPHEROL; ANILINE; CARVONE; CHLOROTHALONIL; CITRAL; DIETHYLENETRIAMINE; DIPHENCYPRONE; EUGENOL; FORMALDEHYDE; GERANIOL; GLUTARALDEHYDE; ISOEUGENOL; LINALOOL; OXAZOLONE; PHENOL; PHENYLENEDIAMINE; RESORCINOL; TETRACHLORSALAN; THIRAM; TOSYLCHLORAMIDE SODIUM; TROPOLONE; COSMETIC; PEPTIDE; WATER;

ACCURACY; ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DEREK ASSAY; DIRECT PEPTIDE REACTIVITY ASSAY; FALSE NEGATIVE RESULT; HUMAN CELL LINE ACTIVATION TEST; INTERMETHOD COMPARISON; LOCAL LYMPH NODE ASSAY; PRIORITY JOURNAL; SKIN SENSITIZATION; SOLUBILITY; ANIMAL TESTING ALTERNATIVE; BIOASSAY; CELL LINE; CHEMISTRY; DRUG EFFECTS; HUMAN; PREDICTIVE VALUE; PROCEDURES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SKIN; SKIN TEST; TOXICITY TESTING;

ANIMAL TESTING ALTERNATIVES; CELL LINE; COSMETICS; ENDPOINT DETERMINATION; HUMANS; LOCAL LYMPH NODE ASSAY; PEPTIDES; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SKIN; SKIN TESTS; SOLUBILITY; TOXICITY TESTS; WATER;

EID: 84942413185     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3127     Document Type: Article

References (30)

1. Ade N, Martinozzi-Teissier S, Pallardy M, Rousset F. 2006. Activation of U937 cells by contact sensitizers: CD86 expression is independent of apoptosis. J. Immunotoxicol. 3: 189-197.
2. Aiba S, Terunuma A, Manome H, Tagami H. 1997. Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules. Eur. J. Immunol. 27: 3031-3038.
3. Ashikaga T, Sakaguchi H, Sono S, Kosaka N, Ishikawa M, Nukada Y, Miyazawa M, Ito Y, Nishiyama N, Itagaki H. 2010. A comparative evaluation of in vitro skin sensitization tests: The Human Cell-line Activation Test (h-CLAT) versus the Local Lymph Node Assay (LLNA). Altern. Lab. Anim. 38: 1-10.
4. Basketter DA, Dearman RJ, Hilton J, Kimber I. 1997. Dinitrohalobenzenes: evaluation of relative skin sensitization potential using the local lymph node assay. Contact Dermatitis 36: 97-100.
5. Basketter DA, Alépée N, Ashikaga T, Barroso J, Gilmour N, Goebel C, Hibatallah J, Hoffmann S, Kern P, Martinozzi-Teissier S, Maxwell G, Reisinger K, Sakaguchi H, Schepky A, Tailhardat M, Templier M. 2014. Categorization of chemicals according to their relative human skin sensitizing potency. Dermatitis 25: 11-21.
6. Bauch C, Kolle SN, Ramirez T, Eltze T, Fabian E, Mehling A, Teubner W, Ravenzwaay BV, Landsiedel R. 2012. Putting the parts together; Combining in vitro methods to test for skin sensitizing potentials. Regul. Toxicol. Pharmacol. 63: 489-504.
7. Cooper JA, Saracci R, Cole P. 1979. Describing the validity of carcinogen screening tests. Br. J. Cancer 39: 87-89.
8. Emter R, Ellis G, Natsch A. 2010. Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro. Toxicol. Appl. Pharmacol. 245: 281-290.
9. Gerberick GF, Vassallo JD, Bailey RE, Chaney JG, Morrall SW, Lepoittevin JP. 2004. Development of a peptide reactivity assay for screening contact allergens. Toxicol. Sci. 81: 332-343.
10. Gerberick GF, Ryan CA, Kern PS, Schlatter H, Dearman RJ, Kimber I, Patlewicz GY, Basketter DA. 2005. Complilation of historical local lymph node data for evaluation of skin sensitization alternative methods. Dermatitis 16: 157-202.
11. Gerberick GF, Cindy AR, Rebecca JD, Kimber I. 2007a. Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals. Methods 41: 54-60.
12. Gerberick GF, Vassallo JD, Foertsch LM, Price BB, Chaney JG, Lepoittevin JP. 2007b. Quantification of chemical peptide reactivity for screening contact allergens: A classification tree model approach. Toxicol. Sci. 97: 417-427.
13. Gerberick GF, Troutman JA, Foertsch LM, Vassallo JD, Quijano M, Dobson RLM, Goebel C, Lepoittevin JP. 2009. Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system. Toxicol. Sci. 112: 164-174.
14. Jaworska J, Dancik Y, Kern P, Gerberick F, Natsch A. 2013. Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice. J. Appl. Toxicol. 33(11): 1353-1364.
15. Jowsey IR, Basketter DA, Westmoreland C, Kimber I. 2006. A future approach to measuring relative skin sensitizing potency: a proposal. J. Appl. Toxicol. 26: 341-350.
16. Kern PS, Gerberick GF, Ryan CA, Kimber I, Aptula A, Basketter DA. 2010. Local lymph node data for the evaluation of skin sensitization alternatives: A second compilation. Dermatitis 21: 8-32.
17. Kimber I, Basketter DA, Gerberick GF, Cindy AR, Rebecca JD. 2011. Chemical allergy: Translating biology into hazard characterization. Toxicol. Sci. 120: S238-S268.
18. Langton K, Patlewicz GY, Long A, Marchant CA, Basketter DA. 2006. Structure-activity relationships for skin sensitization: recent improvements to Derek for Windows. Contact Dermatitis 55: 342-347.
19. Miyazawa M, Ito Y, Kosaka N, Nukada Y, Sakaguchi H, Suzuki H, Nishiyama N. 2008a. Role of MAPK signaling pathway in the activation of dendritic type cell line, THP-1, induced by DNCB and NiSO4. J. Toxicol. Sci. 33: 51-59.
20. Miyazawa M, Ito Y, Kosaka N, Nukada Y, Sakaguchi H, Suzuki H, Nishiyama N. 2008b. Role of TNF-alpha and extracellular ATP in THP-1 cell activation following allergen exposure. J. Toxicol. Sci. 33: 71-83.
21. Natsch A, Gfeller H, Rothaupt M, Ellis G. 2007. Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro. Toxicol. In Vitro 21: 1220-1226.
22. Natsch A, Ryan CA, Foertsch L, Emter R, Jaworska J, Gerberick F, Kern P. 2013. A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation. J. Appl. Toxicol. 33: 1337-1352.
23. Nukada Y, Ashikaga T, Sakaguchi H, Sono S, Mugita N, Hirota M, Miyazawa M, Ito Y, Sasa H, Nishiyama N. 2011. Prediction performance for human skin sensitizing potential of the human cell line activation test (h-CLAT). Contact Dermatitis 65: 343-353.
24. Nukada Y, Ashikaga T, Miyazawa M, Hirota M, Sakaguchi H, Sasa H, Nishiyama N. 2012. Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency. Toxicol. In Vitro 26: 1150-1160.
25. Nukada Y, Miyazawa M, Saitou K, Sakaguchi H, Nishiyama N. 2013. Data integration of non-animal tests for the development of a test battery to prediction the skin sensitizing potential and potency of chemicals. Toxicol. In Vitro 27: 609-618.
26. OECD. 2012. The Adverse Outcome Pathway for Skin Sensitisation initiated by Covalent Binding for Proteins. Part 1. Scientific Evidence. OECD Environment, Health and Safety Publications Series on Testing and Assessment 168: 1-46.
27. OECD. 2015. OECD Guidelines for the Testing of Chemicals. Test No. 442C: In Chemico Skin Sensitisation: Direct Peptide Reactivity Assay (DPRA). Section 4.
28. Sakaguchi H, Ryan C, Ovigne JM, Schroeder KR, Ashikaga T. 2010. Predicting skin sensitization potential and inter-laboratory reproducibility of a human Cell Line Activation Test (h-CLAT) in the European Cosmetics Association (COLIPA) ring trials. Toxicol. In Vitro 24: 1810-1820.
29. Takenouchi O, Miyazawa M, Saito K, Ashikaga T, Sakaguchi H. 2013. Predictive performance of the human Cell Line Activation Test (h-CLAT) for lipophilic chemicals with high octanol-water partition coefficients. J. Toxicol. Sci. 38, 599-609.
30. Tsujita-Inoue K, Hirota M, Ashikaga T, Atobe T, Kouzuki H, Aiba S. 2014. Skin sensitization risk assessment model using artificial neural network analysis of data from multiple in vitro assays. Toxicol. In Vitro 28: 626-639.