-
1
-
-
57449098633
-
Altered redox status accompanies progression to metastatic human bladder cancer
-
Hempel N., Ye H., Abessi B., Mian B., Melendez J.A. Altered redox status accompanies progression to metastatic human bladder cancer. Free Radic. Biol. Med. 2009, 46:42-50.
-
(2009)
Free Radic. Biol. Med.
, vol.46
, pp. 42-50
-
-
Hempel, N.1
Ye, H.2
Abessi, B.3
Mian, B.4
Melendez, J.A.5
-
2
-
-
43249112094
-
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
-
Ishikawa K., Takenaga K., Akimoto M., Koshikawa N., Yamaguchi A., Imanishi H., et al. ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis. Science 2008, 320:661-664.
-
(2008)
Science
, vol.320
, pp. 661-664
-
-
Ishikawa, K.1
Takenaga, K.2
Akimoto, M.3
Koshikawa, N.4
Yamaguchi, A.5
Imanishi, H.6
-
3
-
-
44449142812
-
Reactive oxygen species in tumor metastasis
-
Nishikawa M. Reactive oxygen species in tumor metastasis. Cancer Lett. 2008, 266:53-59.
-
(2008)
Cancer Lett.
, vol.266
, pp. 53-59
-
-
Nishikawa, M.1
-
4
-
-
33846117134
-
The signaling mechanism of ROS in tumor progression
-
Wu W.S. The signaling mechanism of ROS in tumor progression. Cancer Metastasis Rev. 2006, 25:695-705.
-
(2006)
Cancer Metastasis Rev.
, vol.25
, pp. 695-705
-
-
Wu, W.S.1
-
5
-
-
0026021362
-
Production of large amounts of hydrogen peroxide by human tumor cells
-
Szatrowski T.P., Nathan C.F. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 1991, 51:794-798.
-
(1991)
Cancer Res.
, vol.51
, pp. 794-798
-
-
Szatrowski, T.P.1
Nathan, C.F.2
-
6
-
-
77956186783
-
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
-
Hamanaka R.B., Chandel N.S. Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes. Trends Biochem. Sci. 2010, 35:505-513.
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 505-513
-
-
Hamanaka, R.B.1
Chandel, N.S.2
-
7
-
-
75749136883
-
Signaling functions of reactive oxygen species
-
Forman H.J., Maiorino M., Ursini F. Signaling functions of reactive oxygen species. Biochemistry 2010, 49:835-842.
-
(2010)
Biochemistry
, vol.49
, pp. 835-842
-
-
Forman, H.J.1
Maiorino, M.2
Ursini, F.3
-
8
-
-
75749123115
-
Orchestrating redox signaling networks through regulatory cysteine switches
-
Paulsen C.E., Carroll K.S. Orchestrating redox signaling networks through regulatory cysteine switches. ACS Chem. Biol. 2010, 5:47-62.
-
(2010)
ACS Chem. Biol.
, vol.5
, pp. 47-62
-
-
Paulsen, C.E.1
Carroll, K.S.2
-
9
-
-
84875412330
-
Acquisition of the metastatic phenotype is accompanied by H2O2-dependent activation of the p130Cas signaling complex
-
Hempel N., Bartling T.R., Mian B., Melendez J.A. Acquisition of the metastatic phenotype is accompanied by H2O2-dependent activation of the p130Cas signaling complex. Mol. Cancer Res. 2013, 11:303-312.
-
(2013)
Mol. Cancer Res.
, vol.11
, pp. 303-312
-
-
Hempel, N.1
Bartling, T.R.2
Mian, B.3
Melendez, J.A.4
-
10
-
-
70849093542
-
Reactive oxygen species-dependent signaling regulates cancer
-
Weinberg F., Chandel N.S. Reactive oxygen species-dependent signaling regulates cancer. Cell. Mol. Life Sci. 2009, 66:3663-3673.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 3663-3673
-
-
Weinberg, F.1
Chandel, N.S.2
-
11
-
-
20444372545
-
Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation
-
Connor K.M., Subbaram S., Regan K.J., Nelson K.K., Mazurkiewicz J.E., Bartholomew P.J., et al. Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation. J. Biol. Chem. 2005, 280:16916-16924.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16916-16924
-
-
Connor, K.M.1
Subbaram, S.2
Regan, K.J.3
Nelson, K.K.4
Mazurkiewicz, J.E.5
Bartholomew, P.J.6
-
12
-
-
0035500490
-
The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis
-
Chang C., Werb Z. The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol. 2001, 11:S37-S43.
-
(2001)
Trends Cell Biol.
, vol.11
, pp. S37-S43
-
-
Chang, C.1
Werb, Z.2
-
13
-
-
0035188727
-
How matrix metalloproteinases regulate cell behavior
-
Sternlicht M.D., Werb Z. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 2001, 17:463-516.
-
(2001)
Annu. Rev. Cell Dev. Biol.
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
14
-
-
0033848986
-
Matrix metalloproteinases: effectors of development and normal physiology
-
Vu T.H., Werb Z. Matrix metalloproteinases: effectors of development and normal physiology. Genes Dev. 2000, 14:2123-2133.
-
(2000)
Genes Dev.
, vol.14
, pp. 2123-2133
-
-
Vu, T.H.1
Werb, Z.2
-
15
-
-
31344458952
-
Structure and function of matrix metalloproteinases and TIMPs
-
Nagase H., Visse R., Murphy G. Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc. Res. 2006, 69:562-573.
-
(2006)
Cardiovasc. Res.
, vol.69
, pp. 562-573
-
-
Nagase, H.1
Visse, R.2
Murphy, G.3
-
16
-
-
12944288132
-
SiRNA mediated inhibition of MMP-1 reduces invasive potential of a human chondrosarcoma cell line
-
Jiang X., Dutton C.M., Qi W.N., Block J.A., Garamszegi N., Scully S.P. siRNA mediated inhibition of MMP-1 reduces invasive potential of a human chondrosarcoma cell line. J. Cell. Physiol. 2005, 202:723-730.
-
(2005)
J. Cell. Physiol.
, vol.202
, pp. 723-730
-
-
Jiang, X.1
Dutton, C.M.2
Qi, W.N.3
Block, J.A.4
Garamszegi, N.5
Scully, S.P.6
-
17
-
-
0031824909
-
Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer
-
Murray G.I., Duncan M.E., O'Neil P., McKay J.A., Melvin W.T., Fothergill J.E. Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer. J. Pathol. 1998, 185:256-261.
-
(1998)
J. Pathol.
, vol.185
, pp. 256-261
-
-
Murray, G.I.1
Duncan, M.E.2
O'Neil, P.3
McKay, J.A.4
Melvin, W.T.5
Fothergill, J.E.6
-
18
-
-
80051499222
-
MMP-1 expression has an independent prognostic value in breast cancer
-
Bostrom P., Soderstrom M., Vahlberg T., Soderstrom K.O., Roberts P.J., Carpen O., et al. MMP-1 expression has an independent prognostic value in breast cancer. BMC Cancer 2011, 11:348.
-
(2011)
BMC Cancer
, vol.11
, pp. 348
-
-
Bostrom, P.1
Soderstrom, M.2
Vahlberg, T.3
Soderstrom, K.O.4
Roberts, P.J.5
Carpen, O.6
-
19
-
-
17944395146
-
MMP-1 is a prognostic marker for hematogenous metastasis of colorectal cancer
-
Sunami E., Tsuno N., Osada T., Saito S., Kitayama J., Tomozawa S., et al. MMP-1 is a prognostic marker for hematogenous metastasis of colorectal cancer. Oncologist 2000, 5:108-114.
-
(2000)
Oncologist
, vol.5
, pp. 108-114
-
-
Sunami, E.1
Tsuno, N.2
Osada, T.3
Saito, S.4
Kitayama, J.5
Tomozawa, S.6
-
20
-
-
0036240838
-
Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors
-
Vincenti M.P., Brinckerhoff C.E. Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors. Arthritis Res. 2002, 4:157-164.
-
(2002)
Arthritis Res.
, vol.4
, pp. 157-164
-
-
Vincenti, M.P.1
Brinckerhoff, C.E.2
-
21
-
-
0345643514
-
Regulation of matrix metalloproteinase expression in tumor invasion
-
Westermarck J., Kahari V.M. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J. 1999, 13:781-792.
-
(1999)
FASEB J.
, vol.13
, pp. 781-792
-
-
Westermarck, J.1
Kahari, V.M.2
-
22
-
-
2342644797
-
Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke
-
Mercer B.A., Kolesnikova N., Sonett J., D'Armiento J. Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke. J. Biol. Chem. 2004, 279:17690-17696.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 17690-17696
-
-
Mercer, B.A.1
Kolesnikova, N.2
Sonett, J.3
D'Armiento, J.4
-
23
-
-
0036834937
-
Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events
-
Brenneisen P., Sies H., Scharffetter-Kochanek K. Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events. Ann. N. Y. Acad. Sci. 2002, 973:31-43.
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.973
, pp. 31-43
-
-
Brenneisen, P.1
Sies, H.2
Scharffetter-Kochanek, K.3
-
24
-
-
33744910361
-
Redox-dependent matrix metalloproteinase-1 expression is regulated by JNK through Ets and AP-1 promoter motifs
-
Nelson K.K., Subbaram S., Connor K.M., Dasgupta J., Ha X.F., Meng T.C., et al. Redox-dependent matrix metalloproteinase-1 expression is regulated by JNK through Ets and AP-1 promoter motifs. J. Biol. Chem. 2006, 281:14100-14110.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 14100-14110
-
-
Nelson, K.K.1
Subbaram, S.2
Connor, K.M.3
Dasgupta, J.4
Ha, X.F.5
Meng, T.C.6
-
25
-
-
0042849142
-
Elevated Sod2 activity augments matrix metalloproteinase expression: evidence for the involvement of endogenous hydrogen peroxide in regulating metastasis
-
Nelson K.K., Ranganathan A.C., Mansouri J., Rodriguez A.M., Providence K.M., Rutter J.L., et al. Elevated Sod2 activity augments matrix metalloproteinase expression: evidence for the involvement of endogenous hydrogen peroxide in regulating metastasis. Clin. Cancer Res. 2003, 9:424-432.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 424-432
-
-
Nelson, K.K.1
Ranganathan, A.C.2
Mansouri, J.3
Rodriguez, A.M.4
Providence, K.M.5
Rutter, J.L.6
-
26
-
-
0035957989
-
Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation
-
Ranganathan A.C., Nelson K.K., Rodriguez A.M., Kim K.H., Tower G.B., Rutter J.L., et al. Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation. J. Biol. Chem. 2001, 276:14264-14270.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14264-14270
-
-
Ranganathan, A.C.1
Nelson, K.K.2
Rodriguez, A.M.3
Kim, K.H.4
Tower, G.B.5
Rutter, J.L.6
-
27
-
-
0036359548
-
Hypoxia-a key regulatory factor in tumour growth
-
Harris A.L. Hypoxia-a key regulatory factor in tumour growth. Nat. Rev. Cancer 2002, 2:38-47.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
28
-
-
0033776536
-
Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
-
Ohh M., Park C.W., Ivan M., Hoffman M.A., Kim T.Y., Huang L.E., et al. Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nat. Cell Biol. 2000, 2:423-427.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 423-427
-
-
Ohh, M.1
Park, C.W.2
Ivan, M.3
Hoffman, M.A.4
Kim, T.Y.5
Huang, L.E.6
-
29
-
-
0035917313
-
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
-
Ivan M., Kondo K., Yang H., Kim W., Valiando J., Ohh M., et al. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 2001, 292:464-468.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
-
30
-
-
0036469038
-
Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch
-
Lando D., Peet D.J., Whelan D.A., Gorman J.J., Whitelaw M.L. Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. Science 2002, 295:858-861.
-
(2002)
Science
, vol.295
, pp. 858-861
-
-
Lando, D.1
Peet, D.J.2
Whelan, D.A.3
Gorman, J.J.4
Whitelaw, M.L.5
-
31
-
-
33846199233
-
Hypoxia-inducible factors: central regulators of the tumor phenotype
-
Gordan J.D., Simon M.C. Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr. Opin. Genet. Dev. 2007, 17:71-77.
-
(2007)
Curr. Opin. Genet. Dev.
, vol.17
, pp. 71-77
-
-
Gordan, J.D.1
Simon, M.C.2
-
32
-
-
33750630119
-
Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype
-
Holmquist-Mengelbier L., Fredlund E., Lofstedt T., Noguera R., Navarro S., Nilsson H., et al. Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. Cancer Cell 2006, 10:413-423.
-
(2006)
Cancer Cell
, vol.10
, pp. 413-423
-
-
Holmquist-Mengelbier, L.1
Fredlund, E.2
Lofstedt, T.3
Noguera, R.4
Navarro, S.5
Nilsson, H.6
-
33
-
-
75849160216
-
Human cancers converge at the HIF-2alpha oncogenic axis
-
Franovic A., Holterman C.E., Payette J., Lee S. Human cancers converge at the HIF-2alpha oncogenic axis. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:21306-21311.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 21306-21311
-
-
Franovic, A.1
Holterman, C.E.2
Payette, J.3
Lee, S.4
-
34
-
-
0032578458
-
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
-
Chandel N.S., Maltepe E., Goldwasser E., Mathieu C.E., Simon M.C., Schumacker P.T. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:11715-11720.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 11715-11720
-
-
Chandel, N.S.1
Maltepe, E.2
Goldwasser, E.3
Mathieu, C.E.4
Simon, M.C.5
Schumacker, P.T.6
-
37
-
-
24144493814
-
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
-
Guzy R.D., Hoyos B., Robin E., Chen H., Liu L., Mansfield K.D., et al. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab. 2005, 1:401-408.
-
(2005)
Cell Metab.
, vol.1
, pp. 401-408
-
-
Guzy, R.D.1
Hoyos, B.2
Robin, E.3
Chen, H.4
Liu, L.5
Mansfield, K.D.6
-
38
-
-
34250745912
-
The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production
-
Bell E.L., Klimova T.A., Eisenbart J., Moraes C.T., Murphy M.P., Budinger G.R., et al. The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production. J. Cell Biol. 2007, 177:1029-1036.
-
(2007)
J. Cell Biol.
, vol.177
, pp. 1029-1036
-
-
Bell, E.L.1
Klimova, T.A.2
Eisenbart, J.3
Moraes, C.T.4
Murphy, M.P.5
Budinger, G.R.6
-
39
-
-
20344386238
-
Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling
-
Emerling B.M., Platanias L.C., Black E., Nebreda A.R., Davis R.J., Chandel N.S. Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. Mol. Cell. Biol. 2005, 25:4853-4862.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 4853-4862
-
-
Emerling, B.M.1
Platanias, L.C.2
Black, E.3
Nebreda, A.R.4
Davis, R.J.5
Chandel, N.S.6
-
40
-
-
4544346656
-
JunD reduces tumor angiogenesis by protecting cells from oxidative stress
-
Gerald D., Berra E., Frapart Y.M., Chan D.A., Giaccia A.J., Mansuy D., et al. JunD reduces tumor angiogenesis by protecting cells from oxidative stress. Cell 2004, 118:781-794.
-
(2004)
Cell
, vol.118
, pp. 781-794
-
-
Gerald, D.1
Berra, E.2
Frapart, Y.M.3
Chan, D.A.4
Giaccia, A.J.5
Mansuy, D.6
-
41
-
-
33846630894
-
Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro
-
Pan Y., Mansfield K.D., Bertozzi C.C., Rudenko V., Chan D.A., Giaccia A.J., et al. Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro. Mol. Cell. Biol. 2007, 27:912-925.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 912-925
-
-
Pan, Y.1
Mansfield, K.D.2
Bertozzi, C.C.3
Rudenko, V.4
Chan, D.A.5
Giaccia, A.J.6
-
42
-
-
0042564792
-
S-nitrosation of Cys-800 of HIF-1alpha protein activates its interaction with p300 and stimulates its transcriptional activity
-
Yasinska I.M., Sumbayev V.V. S-nitrosation of Cys-800 of HIF-1alpha protein activates its interaction with p300 and stimulates its transcriptional activity. FEBS Lett. 2003, 549:105-109.
-
(2003)
FEBS Lett.
, vol.549
, pp. 105-109
-
-
Yasinska, I.M.1
Sumbayev, V.V.2
-
43
-
-
34247250752
-
NAD(P)H oxidases regulate HIF-2alpha protein expression
-
Block K., Gorin Y., Hoover P., Williams P., Chelmicki T., Clark R.A., et al. NAD(P)H oxidases regulate HIF-2alpha protein expression. J. Biol. Chem. 2007, 282:8019-8026.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 8019-8026
-
-
Block, K.1
Gorin, Y.2
Hoover, P.3
Williams, P.4
Chelmicki, T.5
Clark, R.A.6
-
44
-
-
66749129781
-
Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1
-
Dioum E.M., Chen R., Alexander M.S., Zhang Q., Hogg R.T., Gerard R.D., et al. Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1. Science 2009, 324:1289-1293.
-
(2009)
Science
, vol.324
, pp. 1289-1293
-
-
Dioum, E.M.1
Chen, R.2
Alexander, M.S.3
Zhang, Q.4
Hogg, R.T.5
Gerard, R.D.6
-
45
-
-
0029155694
-
Isolation and characterization of metastatic variants from human transitional cell carcinoma passaged by orthotopic implantation in athymic nude mice
-
Dinney C.P., Fishbeck R., Singh R.K., Eve B., Pathak S., Brown N., et al. Isolation and characterization of metastatic variants from human transitional cell carcinoma passaged by orthotopic implantation in athymic nude mice. J. Urol. 1995, 154:1532-1538.
-
(1995)
J. Urol.
, vol.154
, pp. 1532-1538
-
-
Dinney, C.P.1
Fishbeck, R.2
Singh, R.K.3
Eve, B.4
Pathak, S.5
Brown, N.6
-
46
-
-
35948936350
-
Manganese superoxide dismutase enhances the invasive and migratory activity of tumor cells
-
Connor K.M., Hempel N., Nelson K.K., Dabiri G., Gamarra A., Belarmino J., et al. Manganese superoxide dismutase enhances the invasive and migratory activity of tumor cells. Cancer Res. 2007, 67:10260-10267.
-
(2007)
Cancer Res.
, vol.67
, pp. 10260-10267
-
-
Connor, K.M.1
Hempel, N.2
Nelson, K.K.3
Dabiri, G.4
Gamarra, A.5
Belarmino, J.6
-
47
-
-
84893386949
-
Intracellular redox status controls membrane localization of pro- and anti-migratory signaling molecules
-
Hempel N., Melendez J.A. Intracellular redox status controls membrane localization of pro- and anti-migratory signaling molecules. Redox Biol. 2014, 2:245-250.
-
(2014)
Redox Biol.
, vol.2
, pp. 245-250
-
-
Hempel, N.1
Melendez, J.A.2
-
48
-
-
0037134413
-
Regulation of endothelial matrix metalloproteinase-2 by hypoxia/reoxygenation
-
Ben-Yosef Y., Lahat N., Shapiro S., Bitterman H., Miller A. Regulation of endothelial matrix metalloproteinase-2 by hypoxia/reoxygenation. Circ. Res. 2002, 90:784-791.
-
(2002)
Circ. Res.
, vol.90
, pp. 784-791
-
-
Ben-Yosef, Y.1
Lahat, N.2
Shapiro, S.3
Bitterman, H.4
Miller, A.5
-
49
-
-
46949089391
-
Hypoxia-inducible factor-1alpha regulates matrix metalloproteinase-1 activity in human bone marrow-derived mesenchymal stem cells
-
Lin J.L., Wang M.J., Lee D., Liang C.C., Lin S. Hypoxia-inducible factor-1alpha regulates matrix metalloproteinase-1 activity in human bone marrow-derived mesenchymal stem cells. FEBS Lett. 2008, 582:2615-2619.
-
(2008)
FEBS Lett.
, vol.582
, pp. 2615-2619
-
-
Lin, J.L.1
Wang, M.J.2
Lee, D.3
Liang, C.C.4
Lin, S.5
-
50
-
-
84881257480
-
CAMP-response element-binding protein (CREB) and NF-kappaB transcription factors are activated during prolonged hypoxia and cooperatively regulate the induction of matrix metalloproteinase MMP1
-
Nakayama K. CAMP-response element-binding protein (CREB) and NF-kappaB transcription factors are activated during prolonged hypoxia and cooperatively regulate the induction of matrix metalloproteinase MMP1. J. Biol. Chem. 2013, 288:22584-22595.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 22584-22595
-
-
Nakayama, K.1
-
51
-
-
77953183739
-
Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction
-
Yang S., Kim J., Ryu J.H., Oh H., Chun C.H., Kim B.J., et al. Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction. Nat. Med. 2010, 16:687-693.
-
(2010)
Nat. Med.
, vol.16
, pp. 687-693
-
-
Yang, S.1
Kim, J.2
Ryu, J.H.3
Oh, H.4
Chun, C.H.5
Kim, B.J.6
-
52
-
-
84883709167
-
Matrix metalloproteinase (MMP)-1 induces lung alveolar epithelial cell migration and proliferation, protects from apoptosis, and represses mitochondrial oxygen consumption
-
Herrera I., Cisneros J., Maldonado M., Ramirez R., Ortiz-Quintero B., Anso E., et al. Matrix metalloproteinase (MMP)-1 induces lung alveolar epithelial cell migration and proliferation, protects from apoptosis, and represses mitochondrial oxygen consumption. J. Biol. Chem. 2013, 288:25964-25975.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 25964-25975
-
-
Herrera, I.1
Cisneros, J.2
Maldonado, M.3
Ramirez, R.4
Ortiz-Quintero, B.5
Anso, E.6
-
53
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
Li Z., Bao S., Wu Q., Wang H., Eyler C., Sathornsumetee S., et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 2009, 15:501-513.
-
(2009)
Cancer Cell
, vol.15
, pp. 501-513
-
-
Li, Z.1
Bao, S.2
Wu, Q.3
Wang, H.4
Eyler, C.5
Sathornsumetee, S.6
-
54
-
-
60949102817
-
Hypoxia inducible factor-2alpha: a critical mediator of aggressive tumor phenotypes
-
Qing G., Simon M.C. Hypoxia inducible factor-2alpha: a critical mediator of aggressive tumor phenotypes. Curr. Opin. Genet. Dev. 2009, 19:60-66.
-
(2009)
Curr. Opin. Genet. Dev.
, vol.19
, pp. 60-66
-
-
Qing, G.1
Simon, M.C.2
-
55
-
-
2342597973
-
Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth
-
Kondo K., Kim W.Y., Lechpammer M., Kaelin W.G. Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth. PLoS Biol. 2003, 1.
-
(2003)
PLoS Biol.
, vol.1
-
-
Kondo, K.1
Kim, W.Y.2
Lechpammer, M.3
Kaelin, W.G.4
-
56
-
-
20744445650
-
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
-
Raval R.R., Lau K.W., Tran M.G., Sowter H.M., Mandriota S.J., Li J.L., et al. Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol. Cell. Biol. 2005, 25:5675-5686.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5675-5686
-
-
Raval, R.R.1
Lau, K.W.2
Tran, M.G.3
Sowter, H.M.4
Mandriota, S.J.5
Li, J.L.6
-
57
-
-
68849102685
-
HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice
-
Kim W.Y., Perera S., Zhou B., Carretero J., Yeh J.J., Heathcote S.A., et al. HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice. J. Clin. Invest. 2009, 119:2160-2170.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2160-2170
-
-
Kim, W.Y.1
Perera, S.2
Zhou, B.3
Carretero, J.4
Yeh, J.J.5
Heathcote, S.A.6
-
58
-
-
79957440998
-
The hypoxia-associated factor switches cells from HIF-1alpha- to HIF-2alpha-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion
-
Koh M.Y., Lemos R., Liu X., Powis G. The hypoxia-associated factor switches cells from HIF-1alpha- to HIF-2alpha-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion. Cancer Res. 2011, 71:4015-4027.
-
(2011)
Cancer Res.
, vol.71
, pp. 4015-4027
-
-
Koh, M.Y.1
Lemos, R.2
Liu, X.3
Powis, G.4
-
59
-
-
84879694703
-
Stabilization of HIF-2alpha through redox regulation of mTORC2 activation and initiation of mRNA translation
-
Nayak B.K., Feliers D., Sudarshan S., Friedrichs W.E., Day R.T., New D.D., et al. Stabilization of HIF-2alpha through redox regulation of mTORC2 activation and initiation of mRNA translation. Oncogene 2013, 32:3147-3155.
-
(2013)
Oncogene
, vol.32
, pp. 3147-3155
-
-
Nayak, B.K.1
Feliers, D.2
Sudarshan, S.3
Friedrichs, W.E.4
Day, R.T.5
New, D.D.6
-
60
-
-
34548257176
-
HIF-dependent antitumorigenic effect of antioxidants in vivo
-
Gao P., Zhang H., Dinavahi R., Li F., Xiang Y., Raman V., et al. HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell 2007, 12:230-238.
-
(2007)
Cancer Cell
, vol.12
, pp. 230-238
-
-
Gao, P.1
Zhang, H.2
Dinavahi, R.3
Li, F.4
Xiang, Y.5
Raman, V.6
|