-
1
-
-
49049096562
-
Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer’s disease
-
Boland B, Kumar A, Lee S, Platt FM, Wegiel J, Yu WH, Nixon RA (2008) Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer’s disease. J Neurosci 28:6926-6937.
-
(2008)
J Neurosci
, vol.28
, pp. 6926-6937
-
-
Boland, B.1
Kumar, A.2
Lee, S.3
Platt, F.M.4
Wegiel, J.5
Yu, W.H.6
Nixon, R.A.7
-
2
-
-
84858744141
-
Abeta42 production in brain capillary endothelial cells after oxygen and glucose deprivation
-
Bulbarelli A, Lonati E, Brambilla A, Orlando A, Cazzaniga E, Piazza F, Ferrarese C, Masserini M, Sancini G (2012) Abeta42 production in brain capillary endothelial cells after oxygen and glucose deprivation. Mol Cell Neurosci 49:415-422.
-
(2012)
Mol Cell Neurosci
, vol.49
, pp. 415-422
-
-
Bulbarelli, A.1
Lonati, E.2
Brambilla, A.3
Orlando, A.4
Cazzaniga, E.5
Piazza, F.6
Ferrarese, C.7
Masserini, M.8
Sancini, G.9
-
3
-
-
84858141828
-
Accelerated cortical atrophy in cognitively normal elderly with high beta-amyloid deposition
-
Chetelat G, Villemagne VL, Villain N, Jones G, Ellis KA, Ames D, Martins RN, Masters CL, Rowe CC, Group AR (2012) Accelerated cortical atrophy in cognitively normal elderly with high beta-amyloid deposition. Neurology 78:477-484.
-
(2012)
Neurology
, vol.78
, pp. 477-484
-
-
Chetelat, G.1
Villemagne, V.L.2
Villain, N.3
Jones, G.4
Ellis, K.A.5
Ames, D.6
Martins, R.N.7
Masters, C.L.8
Rowe, C.C.9
Group, A.R.10
-
4
-
-
38349107593
-
The Alzheimer’s disease beta-secretase enzyme, BACE1
-
Cole SL, Vassar R (2007) The Alzheimer’s disease beta-secretase enzyme, BACE1. Mol Neurodegener 2:22.
-
(2007)
Mol Neurodegener
, vol.2
, pp. 22
-
-
Cole, S.L.1
Vassar, R.2
-
6
-
-
0027328680
-
Combined oxygen and glucose deprivation in cortical cell culture: Calcium-dependent and calcium-independent mechanisms of neuronal injury
-
Goldberg MP, Choi DW (1993) Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. J Neurosci 13:3510-3524.
-
(1993)
J Neurosci
, vol.13
, pp. 3510-3524
-
-
Goldberg, M.P.1
Choi, D.W.2
-
7
-
-
84868543653
-
New aminoimidazoles as beta-secretase (BACE-1) inhibitors showing amyloid-beta (Abeta) lowering in brain
-
Gravenfors Y, Viklund J, Blid J, Ginman T, Karlstrom S, Kihlstrom J, Kolmodin K, Lindstrom J, von Berg S, von Kieseritzky F, Bogar K, Slivo C, Swahn BM, Olsson LL, Johansson P, Eketjall S, Falting J, Jeppsson F, Stromberg K, Janson J, Rahm F (2012) New aminoimidazoles as beta-secretase (BACE-1) inhibitors showing amyloid-beta (Abeta) lowering in brain. J Med Chem 55:9297-9311.
-
(2012)
J Med Chem
, vol.55
, pp. 9297-9311
-
-
Gravenfors, Y.1
Viklund, J.2
Blid, J.3
Ginman, T.4
Karlstrom, S.5
Kihlstrom, J.6
Kolmodin, K.7
Lindstrom, J.8
Von Berg, S.9
Von Kieseritzky, F.10
Bogar, K.11
Slivo, C.12
Swahn, B.M.13
Olsson, L.L.14
Johansson, P.15
Eketjall, S.16
Falting, J.17
Jeppsson, F.18
Stromberg, K.19
Janson, J.20
Rahm, F.21
more..
-
8
-
-
0030660722
-
Cerebrovascular pathology in Alzheimer’s disease: Cause, effect or epiphenomenon?
-
Hachinski V, Munoz DG (1997) Cerebrovascular pathology in Alzheimer’s disease: cause, effect or epiphenomenon? Ann N Y Acad Sci 826:1-6.
-
(1997)
Ann N Y Acad Sci
, vol.826
, pp. 1-6
-
-
Hachinski, V.1
Munoz, D.G.2
-
9
-
-
0035833964
-
Poststroke dementia: Incidence and relationship to prestroke cognitive decline
-
Henon H, Durieu I, Guerouaou D, Lebert F, Pasquier F, Leys D (2001) Poststroke dementia: incidence and relationship to prestroke cognitive decline. Neurology 57:1216-1222.
-
(2001)
Neurology
, vol.57
, pp. 1216-1222
-
-
Henon, H.1
Durieu, I.2
Guerouaou, D.3
Lebert, F.4
Pasquier, F.5
Leys, D.6
-
10
-
-
84859385707
-
Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma
-
Hu YL, DeLay M, Jahangiri A, Molinaro AM, Rose SD, Carbonell WS, Aghi MK (2012) Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma. Cancer Res 72:1773-1783.
-
(2012)
Cancer Res
, vol.72
, pp. 1773-1783
-
-
Hu, Y.L.1
Delay, M.2
Jahangiri, A.3
Molinaro, A.M.4
Rose, S.D.5
Carbonell, W.S.6
Aghi, M.K.7
-
11
-
-
84876266454
-
Chaperone-mediated autophagy targets hypoxia-inducible factor-1alpha (HIF-1alpha) for lysosomal degradation
-
Hubbi ME, Hu H, Kshiti Z, Ahmed I, Levchenko A, Semenza GL (2013) Chaperone-mediated autophagy targets hypoxia-inducible factor-1alpha (HIF-1alpha) for lysosomal degradation. J Biol Chem 288:10703-10714.
-
(2013)
J Biol Chem
, vol.288
, pp. 10703-10714
-
-
Hubbi, M.E.1
Hu, H.2
Kshiti, Z.3
Ahmed, I.4
Levchenko, A.5
Semenza, G.L.6
-
12
-
-
84871309604
-
Computational methods in the discovery and design of BACE-1 inhibitors
-
Kacker P, Bottegoni G, Cavalli A (2012) Computational methods in the discovery and design of BACE-1 inhibitors. Curr Med Chem 19:6095-6111.
-
(2012)
Curr Med Chem
, vol.19
, pp. 6095-6111
-
-
Kacker, P.1
Bottegoni, G.2
Cavalli, A.3
-
13
-
-
84858439865
-
Intracerebral microinjection of interleukin-4/interleukin-13 reduces beta-amyloid accumulation in the ipsilateral side and improves cognitive deficits in young amyloid precursor protein 23 mice
-
Kawahara K, Suenobu M, Yoshida A, Koga K, Hyodo A, Ohtsuka H, Kuniyasu A, Tamamaki N, Sugimoto Y, Nakayama H (2012) Intracerebral microinjection of interleukin-4/interleukin-13 reduces beta-amyloid accumulation in the ipsilateral side and improves cognitive deficits in young amyloid precursor protein 23 mice. Neuroscience 207:243-260.
-
(2012)
Neuroscience
, vol.207
, pp. 243-260
-
-
Kawahara, K.1
Suenobu, M.2
Yoshida, A.3
Koga, K.4
Hyodo, A.5
Ohtsuka, H.6
Kuniyasu, A.7
Tamamaki, N.8
Sugimoto, Y.9
Nakayama, H.10
-
14
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky DJ, Abeliovich H, Agostinis P (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4:151-175.
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
-
15
-
-
25444482802
-
BACE is degraded via the lysosomal pathway
-
Koh YH, von Arnim CA, Hyman BT, Tanzi RE, Tesco G (2005) BACE is degraded via the lysosomal pathway. J Biol Chem 280:32499-32504.
-
(2005)
J Biol Chem
, vol.280
, pp. 32499-32504
-
-
Koh, Y.H.1
Von Arnim, C.A.2
Hyman, B.T.3
Tanzi, R.E.4
Tesco, G.5
-
16
-
-
84864471069
-
Inhibition of amyloid-beta peptide aggregation rescues the autophagic deficits in the TgCRND8 mouse model of Alzheimer disease
-
Lai AY, McLaurin J (2012) Inhibition of amyloid-beta peptide aggregation rescues the autophagic deficits in the TgCRND8 mouse model of Alzheimer disease. Biochim Biophys Acta 1822:1629-1637.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 1629-1637
-
-
Lai, A.Y.1
McLaurin, J.2
-
17
-
-
30444440132
-
BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions
-
Laird FM, Cai H, Savonenko AV, Farah MH, He K, Melnikova T, Wen H, Chiang HC, Xu G, Koliatsos VE, Borchelt DR, Price DL, Lee HK, Wong PC (2005) BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions. J Neurosci 25:11693-11709.
-
(2005)
J Neurosci
, vol.25
, pp. 11693-11709
-
-
Laird, F.M.1
Cai, H.2
Savonenko, A.V.3
Farah, M.H.4
He, K.5
Melnikova, T.6
Wen, H.7
Chiang, H.C.8
Xu, G.9
Koliatsos, V.E.10
Borchelt, D.R.11
Price, D.L.12
Lee, H.K.13
Wong, P.C.14
-
18
-
-
84862735174
-
Alzheimer’s Disease Neuroimaging Initiative
-
Landau SM, Mintun MA, Joshi AD, Koeppe RA, Petersen RC, Aisen PS, Weiner MW, Jagust WJ; Alzheimer’s Disease Neuroimaging Initiative (2012) Amyloid deposition, hypometabolism, and longitudinal cognitive decline. Ann Neurol 72:578-586.
-
(2012)
Ann Neurol
, vol.72
, pp. 578-586
-
-
Landau, S.M.1
Mintun, M.A.2
Joshi, A.D.3
Koeppe, R.A.4
Petersen, R.C.5
Aisen, P.S.6
Weiner, M.W.7
Jagust, W.J.8
-
19
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G (2008) Autophagy in the pathogenesis of disease. Cell 132:27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
20
-
-
80053243942
-
Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits
-
Majumder S, Richardson A, Strong R, Oddo S (2011) Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. PLoS One 6:e25416.
-
(2011)
Plos One
, vol.6
-
-
Majumder, S.1
Richardson, A.2
Strong, R.3
Oddo, S.4
-
21
-
-
77951228508
-
Hypoxia-induced autophagy: Cell death or cell survival?
-
Mazure NM, Pouyssegur J (2010) Hypoxia-induced autophagy: cell death or cell survival? Curr Opin Cell Biol 22:177-180.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 177-180
-
-
Mazure, N.M.1
Pouyssegur, J.2
-
22
-
-
77953060341
-
Genetic targeting aromatase in male amyloid precursor protein transgenic mice down-regulates beta-secretase (BACE1) and prevents Alzheimer-like pathology and cognitive impairment
-
McAllister C, Long J, Bowers A, Walker A, Cao P, Honda S, Harada N, Staufenbiel M, Shen Y, Li R (2010) Genetic targeting aromatase in male amyloid precursor protein transgenic mice down-regulates beta-secretase (BACE1) and prevents Alzheimer-like pathology and cognitive impairment. J Neurosci 30:7326-7334.
-
(2010)
J Neurosci
, vol.30
, pp. 7326-7334
-
-
McAllister, C.1
Long, J.2
Bowers, A.3
Walker, A.4
Cao, P.5
Honda, S.6
Harada, N.7
Staufenbiel, M.8
Shen, Y.9
Li, R.10
-
23
-
-
34548847452
-
Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice
-
McConlogue L, Buttini M, Anderson JP, Brigham EF, Chen KS, Freedman SB, Games D, Johnson-Wood K, Lee M, Zeller M, Liu W, Motter R, Sinha S (2007) Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice. J Biol Chem 282:26326-26334.
-
(2007)
J Biol Chem
, vol.282
, pp. 26326-26334
-
-
McConlogue, L.1
Buttini, M.2
Erson, J.P.3
Brigham, E.F.4
Chen, K.S.5
Freedman, S.B.6
Games, D.7
Johnson-Wood, K.8
Lee, M.9
Zeller, M.10
Liu, W.11
Motter, R.12
Sinha, S.13
-
24
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima N, Yoshimori T, Levine B (2010) Methods in mammalian autophagy research. Cell 140:313-326.
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
25
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ (2008) Autophagy fights disease through cellular self-digestion. Nature 451:1069-1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
26
-
-
0034644836
-
Regulation of APP cleavage by alpha-, betaand gamma-secretases
-
Nunan J, Small DH (2000) Regulation of APP cleavage by alpha-, betaand gamma-secretases. FEBS Lett 483:6-10.
-
(2000)
FEBS Lett
, vol.483
, pp. 6-10
-
-
Nunan, J.1
Small, D.H.2
-
27
-
-
84860299843
-
Soluble amyloid precursor protein-alpha modulates beta-secretase activity and amyloid-beta generation
-
Obregon D, Hou H, Deng J, Giunta B, Tian J, Darlington D, Shahaduzzaman M, Zhu Y, Mori T, Mattson MP, Tan J (2012) Soluble amyloid precursor protein-alpha modulates beta-secretase activity and amyloid-beta generation. Nat Commun 3:777.
-
(2012)
Nat Commun
, vol.3
, pp. 777
-
-
Obregon, D.1
Hou, H.2
Deng, J.3
Giunta, B.4
Tian, J.5
Darlington, D.6
Shahaduzzaman, M.7
Zhu, Y.8
Mori, T.9
Mattson, M.P.10
Tan, J.11
-
28
-
-
33947247360
-
BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice
-
Ohno M, Cole SL, Yasvoina M, Zhao J, Citron M, Berry R, Disterhoft JF, Vassar R (2007) BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice. Neurobiol Dis 26:134-145.
-
(2007)
Neurobiol Dis
, vol.26
, pp. 134-145
-
-
Ohno, M.1
Cole, S.L.2
Yasvoina, M.3
Zhao, J.4
Citron, M.5
Berry, R.6
Disterhoft, J.F.7
Vassar, R.8
-
29
-
-
0346055155
-
BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer’s disease
-
Ohno M, Sametsky EA, Younkin LH, Oakley H, Younkin SG, Citron M, Vassar R, Disterhoft JF (2004) BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer’s disease. Neuron 41:27-33.
-
(2004)
Neuron
, vol.41
, pp. 27-33
-
-
Ohno, M.1
Sametsky, E.A.2
Younkin, L.H.3
Oakley, H.4
Younkin, S.G.5
Citron, M.6
Vassar, R.7
Disterhoft, J.F.8
-
30
-
-
70449132694
-
Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: A systematic review and meta-analysis
-
Pendlebury ST, Rothwell PM (2009) Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis. Lancet Neurol 8:1006-1018.
-
(2009)
Lancet Neurol
, vol.8
, pp. 1006-1018
-
-
Pendlebury, S.T.1
Rothwell, P.M.2
-
31
-
-
84862700955
-
The early contribution of cerebrovascular factors to the pathogenesis of Alzheimer’s disease
-
Pimentel-Coelho PM, Rivest S (2012) The early contribution of cerebrovascular factors to the pathogenesis of Alzheimer’s disease. Eur J Neurosci 35:1917-1937.
-
(2012)
Eur J Neurosci
, vol.35
, pp. 1917-1937
-
-
Pimentel-Coelho, P.M.1
Rivest, S.2
-
32
-
-
82155185594
-
Cognitive impairment with vascular impairment and degeneration
-
Pluta R, Jolkkonen J, Cuzzocrea S, Pedata F, Cechetto D, Popa-Wagner A (2011) Cognitive impairment with vascular impairment and degeneration. Curr Neurovasc Res 8:342-350.
-
(2011)
Curr Neurovasc Res
, vol.8
, pp. 342-350
-
-
Pluta, R.1
Jolkkonen, J.2
Cuzzocrea, S.3
Pedata, F.4
Cechetto, D.5
Popa-Wagner, A.6
-
33
-
-
78149475088
-
Regulation of mammalian autophagy in physiology and pathophysiology
-
Ravikumar B, Sarkar S, Davies JE, Futter M, Garcia-Arencibia M, Green-Thompson ZW, Jimenez-Sanchez M, Korolchuk VI, Lichtenberg M, Luo S, Massey DC, Menzies FM, Moreau K, Narayanan U, Renna M, Siddiqi FH, Underwood BR, Winslow AR, Rubinsztein DC (2010) Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev 90:1383-1435.
-
(2010)
Physiol Rev
, vol.90
, pp. 1383-1435
-
-
Ravikumar, B.1
Sarkar, S.2
Davies, J.E.3
Futter, M.4
Garcia-Arencibia, M.5
Green-Thompson, Z.W.6
Jimenez-Sanchez, M.7
Korolchuk, V.I.8
Lichtenberg, M.9
Luo, S.10
Massey, D.C.11
Menzies, F.M.12
Moreau, K.13
Narayanan, U.14
Renna, M.15
Siddiqi, F.H.16
Underwood, B.R.17
Winslow, A.R.18
Rubinsztein, D.C.19
-
34
-
-
76349095132
-
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
-
Semenza GL (2010) Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 29:625-634.
-
(2010)
Oncogene
, vol.29
, pp. 625-634
-
-
Semenza, G.L.1
-
35
-
-
77956305343
-
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer’s disease
-
Spilman P, Podlutskaya N, Hart MJ, Debnath J, Gorostiza O, Bredesen D, Richardson A, Strong R, Galvan V (2010) Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer’s disease. PLoS One 5:e9979.
-
(2010)
Plos One
, vol.5
-
-
Spilman, P.1
Podlutskaya, N.2
Hart, M.J.3
Debnath, J.4
Gorostiza, O.5
Bredesen, D.6
Richardson, A.7
Strong, R.8
Galvan, V.9
-
36
-
-
33845505233
-
Hypoxia facilitates Alzheimer’s disease pathogenesis by up-regulating BACE1 gene expression
-
Sun X, He G, Qing H, Zhou W, Dobie F, Cai F, Staufenbiel M, Huang LE, Song W (2006) Hypoxia facilitates Alzheimer’s disease pathogenesis by up-regulating BACE1 gene expression. Proc Natl Acad Sci U S A 103:18727-18732.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 18727-18732
-
-
Sun, X.1
He, G.2
Qing, H.3
Zhou, W.4
Dobie, F.5
Cai, F.6
Staufenbiel, M.7
Huang, L.E.8
Song, W.9
-
37
-
-
0347986620
-
Class III phosphoinositide 3-kinase-Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes
-
Tassa A, Roux MP, Attaix D, Bechet DM (2003) Class III phosphoinositide 3-kinase-Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes. Biochem J 376:577-586.
-
(2003)
Biochem J
, vol.376
, pp. 577-586
-
-
Tassa, A.1
Roux, M.P.2
Attaix, D.3
Bechet, D.M.4
-
38
-
-
0035159756
-
The beta-secretase, BACE: A prime drug target for Alzheimer’s disease
-
Vassar R (2001) The beta-secretase, BACE: a prime drug target for Alzheimer’s disease. J Mol Neurosci 17:157-170.
-
(2001)
J Mol Neurosci
, vol.17
, pp. 157-170
-
-
Vassar, R.1
-
39
-
-
15944378214
-
Beta-Secretase, APP and Abeta in Alzheimer’s disease
-
Vassar R (2005) beta-Secretase, APP and Abeta in Alzheimer’s disease. Subcell Biochem 38:79-103.
-
(2005)
Subcell Biochem
, vol.38
, pp. 79-103
-
-
Vassar, R.1
-
40
-
-
77950688910
-
Decay accelerating factor (CD55) protects neuronal cells from chemical hypoxia-induced injury
-
Wang Y, Li Y, Dalle Lucca SL, Simovic M, Tsokos GC, Dalle Lucca JJ (2010) Decay accelerating factor (CD55) protects neuronal cells from chemical hypoxia-induced injury. J Neuroinflammation 7:24.
-
(2010)
J Neuroinflammation
, vol.7
, pp. 24
-
-
Wang, Y.1
Li, Y.2
Dalle Lucca, S.L.3
Simovic, M.4
Tsokos, G.C.5
Dalle Lucca, J.J.6
-
41
-
-
26444587508
-
Macroautophagy-a novel Beta-amyloid peptide-generating pathway activated in Alzheimer’s disease
-
Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, Naslund J, Mathews PM, Cataldo AM, Nixon RA (2005) Macroautophagy-a novel Beta-amyloid peptide-generating pathway activated in Alzheimer’s disease. J Cell Biol 171:87-98.
-
(2005)
J Cell Biol
, vol.171
, pp. 87-98
-
-
Yu, W.H.1
Cuervo, A.M.2
Kumar, A.3
Peterhoff, C.M.4
Schmidt, S.D.5
Lee, J.H.6
Mohan, P.S.7
Mercken, M.8
Farmery, M.R.9
Tjernberg, L.O.10
Jiang, Y.11
Duff, K.12
Uchiyama, Y.13
Naslund, J.14
Mathews, P.M.15
Cataldo, A.M.16
Nixon, R.A.17
-
42
-
-
84870567934
-
SUMO1 modulates Abeta generation via BACE1 accumulation
-
Yun SM, Cho SJ, Song JC, Song SY, Jo SA, Jo C, Yoon K, Tanzi RE, Choi EJ, Koh YH (2013) SUMO1 modulates Abeta generation via BACE1 accumulation. Neurobiol Aging 34:650-662.
-
(2013)
Neurobiol Aging
, vol.34
, pp. 650-662
-
-
Yun, S.M.1
Cho, S.J.2
Song, J.C.3
Song, S.Y.4
Jo, S.A.5
Jo, C.6
Yoon, K.7
Tanzi, R.E.8
Choi, E.J.9
Koh, Y.H.10
-
43
-
-
79955973768
-
3-n-Butylphthalide (NBP) attenuated neuronal autophagy and amyloid-beta expression in diabetic mice subjected to brain ischemia
-
Zhang T, Yan W, Li Q, Fu J, Liu K, Jia W, Sun X, Liu X (2011) 3-n-Butylphthalide (NBP) attenuated neuronal autophagy and amyloid-beta expression in diabetic mice subjected to brain ischemia. Neurol Res 33:396-404.
-
(2011)
Neurol Res
, vol.33
, pp. 396-404
-
-
Zhang, T.1
Yan, W.2
Li, Q.3
Fu, J.4
Liu, K.5
Jia, W.6
Sun, X.7
Liu, X.8
-
44
-
-
34249727115
-
Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation
-
Zhang X, Zhou K, Wang R, Cui J, Lipton SA, Liao FF, Xu H, Zhang YW (2007) Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation. J Biol Chem 282:10873-10880.
-
(2007)
J Biol Chem
, vol.282
, pp. 10873-10880
-
-
Zhang, X.1
Zhou, K.2
Wang, R.3
Cui, J.4
Lipton, S.A.5
Liao, F.F.6
Xu, H.7
Zhang, Y.W.8
-
45
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
-
Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL (2000) Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 60:1541-1545.
-
(2000)
Cancer Res
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
Laughner, E.4
Hanrahan, C.5
Georgescu, M.M.6
Simons, J.W.7
Semenza, G.L.8
-
46
-
-
84866375926
-
Dynamin 1 regulates amyloid generation through modulation of BACE- 1
-
Zhu L, Su M, Lucast L, Liu L, Netzer WJ, Gandy SE, Cai D (2012) Dynamin 1 regulates amyloid generation through modulation of BACE- 1. PLoS One 7:e45033.
-
(2012)
Plos One
, vol.7
-
-
Zhu, L.1
Su, M.2
Lucast, L.3
Liu, L.4
Netzer, W.J.5
Gandy, S.E.6
Cai, D.7
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