SUMO1 modulates Aβ generation via BACE1 accumulation

Neurobiology of Aging

Volumn 34, Issue 3, 2013, Pages 650-662

  Yun, Sang Moon ^a,b   Cho, Sun Jung ^a   Song, Jae Chun ^a   Song, Sung Yeon ^a   Jo, Sangmee Ahn ^c   Jo, Chulman ^a   Yoon, Keejung ^d   Tanzi, Rudolph E ^e   Choi, Eui Ju ^b   Koh, Young Ho ^a  

^a Korea National Institute of Health   (South Korea)

^b Korea University   (South Korea)

^c Dankook University   (South Korea)

^d Sungkyunkwan University   (South Korea)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alzheimer's disease; Amyloid peptide; BACE1; SUMO1

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; BRAIN PROTEIN; LEUCINE; SUMO 1 PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN LEVEL; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME METABOLISM; ENZYME REGULATION; GAIN OF FUNCTION MUTATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; LOSS OF FUNCTION MUTATION; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEIN TARGETING; REGULATORY MECHANISM; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMINO ACID MOTIFS; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; HEK293 CELLS; HUMANS; MICE; MICE, TRANSGENIC; NEURONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUMO-1 PROTEIN;

EID: 84870567934     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.08.005     Document Type: Article

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