-
1
-
-
34548588559
-
How human neutrophils kill and degrade microbes: An integrated view
-
Nauseef WM. How human neutrophils kill and degrade microbes: an integrated view. Immunol Rev 2007;219:88-102
-
(2007)
Immunol Rev
, vol.219
, pp. 88-102
-
-
Nauseef, W.M.1
-
2
-
-
84890569327
-
The potential of neutrophil elastase inhibitors as antiinflammatory therapies
-
Henriksen PA. The potential of neutrophil elastase inhibitors as antiinflammatory therapies. Cur Opin Hematol 2014;21(1):23-8
-
(2014)
Cur Opin Hematol
, vol.21
, Issue.1
, pp. 23-28
-
-
Henriksen, P.A.1
-
3
-
-
84879291920
-
The neutrophil in chronic obstructive pulmonary disease
-
Hoenderdos K, Condliffe A. The neutrophil in chronic obstructive pulmonary disease. Am J Respir Cell Molecul Biol 2013;48(5):531-9
-
(2013)
Am J Respir Cell Molecul Biol
, vol.48
, Issue.5
, pp. 531-539
-
-
Hoenderdos, K.1
Condliffe, A.2
-
6
-
-
0027178868
-
Human leukocyte elastase and cathepsin G inactivate factor VII by limited proteolysis
-
Anderssen T, Halvorsen H, Bajaj SP, Osterud B. Human leukocyte elastase and cathepsin G inactivate factor VII by limited proteolysis. Thromb Haemost 1993;70(3):414-17
-
(1993)
Thromb Haemost
, vol.70
, Issue.3
, pp. 414-417
-
-
Anderssen, T.1
Halvorsen, H.2
Bajaj, S.P.3
Osterud, B.4
-
7
-
-
0025766045
-
Degradation of human factor X by human polymorphonuclear leucocyte cathepsin G and elastase
-
Turkington PT. Degradation of human factor X by human polymorphonuclear leucocyte cathepsin G and elastase. Haemostasis 1991;21(2):111-16
-
(1991)
Haemostasis
, vol.21
, Issue.2
, pp. 111-116
-
-
Turkington, P.T.1
-
8
-
-
0027998135
-
The role of neutrophil elastase in chronic inflammation
-
Doring G. The role of neutrophil elastase in chronic inflammation. Am J Respir Crit Care Med 1994;150(6 Pt 2):S114-17
-
(1994)
Am J Respir Crit Care Med
, vol.150
, Issue.6
, pp. S114-S117
-
-
Doring, G.1
-
10
-
-
0028019608
-
The role of proteinases in the pathogenesis of chronic bronchitis
-
Stockley RA. The role of proteinases in the pathogenesis of chronic bronchitis. Am J Respir Crit Care Med 1994;150(6 Pt 2):S109-13
-
(1994)
Am J Respir Crit Care Med
, vol.150
, Issue.6
, pp. S109-S113
-
-
Stockley, R.A.1
-
11
-
-
0025279912
-
The adult respiratory distress syndrome: Definition and prognosis, pathogenesis and treatment
-
Wiener-Kronish JP, Gropper MA, Matthay MA. The adult respiratory distress syndrome: definition and prognosis, pathogenesis and treatment. Br J Anaesth 1990;65(1):107-29
-
(1990)
Br J Anaesth
, vol.65
, Issue.1
, pp. 107-129
-
-
Wiener-Kronish, J.P.1
Gropper, M.A.2
Matthay, M.A.3
-
12
-
-
84911922929
-
Increased neutrophil elastase and proteinase 3 and augmented NETosis are closely associated with beta-cell autoimmunity in patients with type 1 diabetes
-
Wang Y, Xiao Y, Zhong L, et al. Increased neutrophil elastase and proteinase 3 and augmented NETosis are closely associated with beta-cell autoimmunity in patients with type 1 diabetes. Diabetes 2014;63(12):4239-48.
-
(2014)
Diabetes
, vol.63
, Issue.12
, pp. 4239-4248
-
-
Wang, Y.1
Xiao, Y.2
Zhong, L.3
-
14
-
-
77749333226
-
Acute lung injury with alveolar hemorrhage due to a novel swine-origin influenza A (H1N1) virus
-
Yokoyama T, Tsushima K, Ushiki A, et al. Acute lung injury with alveolar hemorrhage due to a novel swine-origin influenza A (H1N1) virus. Int Med 2010;49(5):427-30
-
(2010)
Int Med
, vol.49
, Issue.5
, pp. 427-430
-
-
Yokoyama, T.1
Tsushima, K.2
Ushiki, A.3
-
15
-
-
84979195063
-
Effect of a selective neutrophil elastase inhibitor on mortality and ventilator-free days in patients with increased extravascular lung water: A post hoc analysis of the PiCCO Pulmonary Edema Study
-
Tagami T, Tosa R, Omura M, et al. Effect of a selective neutrophil elastase inhibitor on mortality and ventilator-free days in patients with increased extravascular lung water: a post hoc analysis of the PiCCO Pulmonary Edema Study. J Inten Care 2014;2(1):67
-
(2014)
J Inten Care
, vol.2
, Issue.1
, pp. 67
-
-
Tagami, T.1
Tosa, R.2
Omura, M.3
-
16
-
-
3943106162
-
Neutrophil elastase inhibition in acute lung injury: Results of the STRIVE study
-
Zeiher BG, Artigas A, Vincent JL, et al. Neutrophil elastase inhibition in acute lung injury: results of the STRIVE study. Crit Care Med 2004;32(8):1695-702
-
(2004)
Crit Care Med
, vol.32
, Issue.8
, pp. 1695-1702
-
-
Zeiher, B.G.1
Artigas, A.2
Vincent, J.L.3
-
17
-
-
33845716414
-
Phosphodiesterase-4 inhibitors as a novel approach for the treatment of respiratory disease: Cilomilast
-
Kroegel C, Foerster M. Phosphodiesterase-4 inhibitors as a novel approach for the treatment of respiratory disease: cilomilast. Expert Opin Investig Drugs 2007;16(1):109-24
-
(2007)
Expert Opin Investig Drugs
, vol.16
, Issue.1
, pp. 109-124
-
-
Kroegel, C.1
Foerster, M.2
-
18
-
-
84922079549
-
Phosphodiesterase inhibitors for chronic obstructive pulmonary disease: What does the future hold?
-
Matera MG, Rogliani P, Calzetta L, Cazzola M. Phosphodiesterase inhibitors for chronic obstructive pulmonary disease: what does the future hold? Drugs 2014;74(17):1983-92
-
(2014)
Drugs
, vol.74
, Issue.17
, pp. 1983-1992
-
-
Matera, M.G.1
Rogliani, P.2
Calzetta, L.3
Cazzola, M.4
-
19
-
-
0024430531
-
Elastase and cathepsin G of human monocytes
-
Campbell EJ, Silverman EK, Campbell MA. Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastasemediated proteolytic activity. J Immunol 1989;143(9):2961-8
-
(1989)
Quantification of Cellular Content, Release in Response to Stimuli, and Heterogeneity in Elastasemediated Proteolytic Activity. J Immunol
, vol.143
, Issue.9
, pp. 2961-2968
-
-
Campbell, E.J.1
Silverman, E.K.2
Campbell, M.A.3
-
20
-
-
0026543741
-
Identification of elastase in human eosinophils: Immunolocalization, isolation, and partial characterization
-
Lungarella G, Menegazzi R, Gardi C, et al. Identification of elastase in human eosinophils: immunolocalization, isolation, and partial characterization. Arch Biochem Biophys 1992;292(1):128-35
-
(1992)
Arch Biochem Biophys
, vol.292
, Issue.1
, pp. 128-135
-
-
Lungarella, G.1
Menegazzi, R.2
Gardi, C.3
-
21
-
-
0035437546
-
The role of elastases secreted by fibroblasts in wrinkle formation: Implication through selective inhibition of elastase activity
-
Tsuji N, Moriwaki S, Suzuki Y, et al. The role of elastases secreted by fibroblasts in wrinkle formation: implication through selective inhibition of elastase activity. Photochem Photobiol 2001;74(2):283-90
-
(2001)
Photochem Photobiol
, vol.74
, Issue.2
, pp. 283-290
-
-
Tsuji, N.1
Moriwaki, S.2
Suzuki, Y.3
-
22
-
-
0028787054
-
Nonisotropic enzyme-inhibitor interactions: A novel nonoxidative mechanism for quantum proteolysis by human neutrophils
-
Liou TG, Campbell EJ. Nonisotropic enzyme-inhibitor interactions: a novel nonoxidative mechanism for quantum proteolysis by human neutrophils. Biochemistry 1995;34(49):16171-7
-
(1995)
Biochemistry
, vol.34
, Issue.49
, pp. 16171-16177
-
-
Liou, T.G.1
Campbell, E.J.2
-
23
-
-
0242713072
-
Neutrophil granules and secretory vesicles in inflammation
-
Faurschou M, Borregaard N. Neutrophil granules and secretory vesicles in inflammation. Microbes Infect 2003;5(14):1317-27
-
(2003)
Microbes Infect
, vol.5
, Issue.14
, pp. 1317-1327
-
-
Faurschou, M.1
Borregaard, N.2
-
24
-
-
84859950056
-
NSP4, an elastase-related protease in human neutrophils with arginine specificity
-
Perera NC, Schilling O, Kittel H, et al. NSP4, an elastase-related protease in human neutrophils with arginine specificity. Proc Nat Acad Sci USA 2012;109(16):6229-34
-
(2012)
Proc Nat Acad Sci USA
, vol.109
, Issue.16
, pp. 6229-6234
-
-
Perera, N.C.1
Schilling, O.2
Kittel, H.3
-
25
-
-
0026754577
-
Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter
-
Zimmer M, Medcalf RL, Fink TM, et al. Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter. Proc Nat Acad Sci USA 1992;89(17):8215-19
-
(1992)
Proc Nat Acad Sci USA
, vol.89
, Issue.17
, pp. 8215-8219
-
-
Zimmer, M.1
Medcalf, R.L.2
Fink, T.M.3
-
26
-
-
33847395071
-
Neutrophil elastase in cyclic and severe congenital neutropenia
-
Horwitz MS, Duan Z, Korkmaz B, et al. Neutrophil elastase in cyclic and severe congenital neutropenia. Blood 2007;109(5):1817-24
-
(2007)
Blood
, vol.109
, Issue.5
, pp. 1817-1824
-
-
Horwitz, M.S.1
Duan, Z.2
Korkmaz, B.3
-
27
-
-
18644377252
-
Elastolytic proteases: Inflammation resolution and dysregulation in chronic infective lung disease
-
Taggart CC, Greene CM, Carroll TP, et al. Elastolytic proteases: inflammation resolution and dysregulation in chronic infective lung disease. Am J Respir Crit Care Med 2005;171(10):1070-6
-
(2005)
Am J Respir Crit Care Med
, vol.171
, Issue.10
, pp. 1070-1076
-
-
Taggart, C.C.1
Greene, C.M.2
Carroll, T.P.3
-
28
-
-
16244397365
-
Neutrophil serine proteases: Potential key regulators of cell signalling during inflammation
-
Wiedow O, Meyer-Hoffert U. Neutrophil serine proteases: potential key regulators of cell signalling during inflammation. J Int Med 2005;257(4):319-28
-
(2005)
J Int Med
, vol.257
, Issue.4
, pp. 319-328
-
-
Wiedow, O.1
Meyer-Hoffert, U.2
-
29
-
-
0038018539
-
Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4
-
Devaney JM, Greene CM, Taggart CC, et al. Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4. FEBS Lett 2003;544(1-3):129-32
-
(2003)
FEBS Lett
, vol.544
, Issue.1-3
, pp. 129-132
-
-
Devaney, J.M.1
Greene, C.M.2
Taggart, C.C.3
-
30
-
-
0035112806
-
More than destructive: Neutrophil-derived serine proteases in cytokine bioactivity control
-
Bank U, Ansorge S. More than destructive: neutrophil-derived serine proteases in cytokine bioactivity control. J Leukoc Biol 2001;69(2):197-206
-
(2001)
J Leukoc Biol
, vol.69
, Issue.2
, pp. 197-206
-
-
Bank, U.1
Ansorge, S.2
-
31
-
-
84887852110
-
Neutrophil elastase and proteinase-3 trigger G protein-biased signaling through proteinase-activated receptor-1 (PAR1)
-
Mihara K, Ramachandran R, Renaux B, et al. Neutrophil elastase and proteinase-3 trigger G protein-biased signaling through proteinase-activated receptor-1 (PAR1). J Biol Chem 2013;288(46):32979-90
-
(2013)
J Biol Chem
, vol.288
, Issue.46
, pp. 32979-32990
-
-
Mihara, K.1
Ramachandran, R.2
Renaux, B.3
-
32
-
-
70949084458
-
Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NFkappaB-, and p53-dependent pathway
-
Suzuki T, Yamashita C, Zemans RL, et al. Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NFkappaB-, and p53-dependent pathway. Am J Respir Cell Molecul Biol 2009;41(6):742-55
-
(2009)
Am J Respir Cell Molecul Biol
, vol.41
, Issue.6
, pp. 742-755
-
-
Suzuki, T.1
Yamashita, C.2
Zemans, R.L.3
-
33
-
-
84875683938
-
Neutrophil elastase induces MUC5AC secretion via proteaseactivated receptor 2
-
Zhou J, Perelman JM, Kolosov VP, Zhou X. Neutrophil elastase induces MUC5AC secretion via proteaseactivated receptor 2. Mol Cell Biochem 2013;377(1-2):75-85
-
(2013)
Mol Cell Biochem
, vol.377
, Issue.1-2
, pp. 75-85
-
-
Zhou, J.1
Perelman, J.M.2
Kolosov, V.P.3
Zhou, X.4
-
34
-
-
3042686384
-
Neutrophil serine proteinases inactivate surfactant protein D by cleaving within a conserved subregion of the carbohydrate recognition domain
-
Hirche TO, Crouch EC, Espinola M, et al. Neutrophil serine proteinases inactivate surfactant protein D by cleaving within a conserved subregion of the carbohydrate recognition domain. J Biol Chem 2004;279(26):27688-98
-
(2004)
J Biol Chem
, vol.279
, Issue.26
, pp. 27688-27698
-
-
Hirche, T.O.1
Crouch, E.C.2
Espinola, M.3
-
35
-
-
0347994948
-
Proteolytic regulation of the urokinase receptor/CD87 on monocytic cells by neutrophil elastase and cathepsin G
-
Beaufort N, Leduc D, Rousselle JC, et al. Proteolytic regulation of the urokinase receptor/CD87 on monocytic cells by neutrophil elastase and cathepsin G. J Immunol 2004;172(1):540-9
-
(2004)
J Immunol
, vol.172
, Issue.1
, pp. 540-549
-
-
Beaufort, N.1
Leduc, D.2
Rousselle, J.C.3
-
36
-
-
0029067051
-
Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis
-
Doring G, Frank F, Boudier C, et al. Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis. J Immunol 1995;154(9):4842-50
-
(1995)
J Immunol
, vol.154
, Issue.9
, pp. 4842-4850
-
-
Doring, G.1
Frank, F.2
Boudier, C.3
-
37
-
-
0025773838
-
Role of mast cell and neutrophil proteases in airway secretion
-
Nadel JA. Role of mast cell and neutrophil proteases in airway secretion. Am Rev Respir Dis 1991;144(3 Pt 2):S48-51
-
(1991)
Am Rev Respir Dis
, vol.144
, Issue.3
, pp. S48-51
-
-
Nadel, J.A.1
-
38
-
-
0036151252
-
Human leukocyte elastase induces keratinocyte proliferation in vitro and in vivo
-
Rogalski C, Meyer-Hoffert U, Proksch E, Wiedow O. Human leukocyte elastase induces keratinocyte proliferation in vitro and in vivo. J Invest Dermatol 2002;118(1):49-54
-
(2002)
J Invest Dermatol
, vol.118
, Issue.1
, pp. 49-54
-
-
Rogalski, C.1
Meyer-Hoffert, U.2
Proksch, E.3
Wiedow, O.4
-
39
-
-
0027155816
-
Enhancement of cathepsin G-induced platelet activation by leukocyte elastase: Consequence for the neutrophil-mediated platelet activation
-
Renesto P, Chignard M. Enhancement of cathepsin G-induced platelet activation by leukocyte elastase: consequence for the neutrophil-mediated platelet activation. Blood 1993;82(1):139-44
-
(1993)
Blood
, vol.82
, Issue.1
, pp. 139-144
-
-
Renesto, P.1
Chignard, M.2
-
40
-
-
0030055779
-
Inhibition of neutrophil elastase suppresses the development of skin tumors in hairless mice
-
Starcher B, O'Neal P, Granstein RD, Beissert S. Inhibition of neutrophil elastase suppresses the development of skin tumors in hairless mice. J Invest Dermatol 1996;107(2):159-63
-
(1996)
J Invest Dermatol
, vol.107
, Issue.2
, pp. 159-163
-
-
Starcher, B.1
O'Neal, P.2
Granstein, R.D.3
Beissert, S.4
-
41
-
-
1342287837
-
Role of imbalance between neutrophil elastase and alpha 1-antitrypsin in cancer development and progression
-
Sun Z, Yang P. Role of imbalance between neutrophil elastase and alpha 1-antitrypsin in cancer development and progression. Lancet Oncol 2004;5(3):182-90
-
(2004)
Lancet Oncol
, vol.5
, Issue.3
, pp. 182-190
-
-
Sun, Z.1
Yang, P.2
-
42
-
-
0025360691
-
The proteaseantiprotease balance within the human lung: Implications for the pathogenesis of emphysema
-
Gadek JE, Pacht ER. The proteaseantiprotease balance within the human lung: implications for the pathogenesis of emphysema. Lung 1990;168 Suppl:552-64
-
(1990)
Lung
, vol.168
, pp. 552-564
-
-
Gadek, J.E.1
Pacht, E.R.2
-
43
-
-
0029794112
-
Alpha-1-antitrypsin deficiency: Biochemistry and clinical manifestations
-
Perlmutter DH. Alpha-1-antitrypsin deficiency: biochemistry and clinical manifestations. Ann Med 1996;28(5):385-94
-
(1996)
Ann Med
, vol.28
, Issue.5
, pp. 385-394
-
-
Perlmutter, D.H.1
-
44
-
-
0035823595
-
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature
-
Silverman GA, Bird PI, Carrell RW, et al. The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Bio Chem 2001;276(36):33293-6
-
(2001)
J Bio Chem
, vol.276
, Issue.36
, pp. 33293-33296
-
-
Silverman, G.A.1
Bird, P.I.2
Carrell, R.W.3
-
45
-
-
0024333351
-
Alpha-macroglobulins: Structure, shape, and mechanism of proteinase complex formation
-
Sottrup-Jensen L. Alpha-macroglobulins: structure, shape, and mechanism of proteinase complex formation. J Biol Chem 1989;264(20):11539-42
-
(1989)
J Biol Chem
, vol.264
, Issue.20
, pp. 11539-11542
-
-
Sottrup-Jensen, L.1
-
46
-
-
0023937510
-
Structure, function, and control of neutrophil proteinases
-
Travis J. Structure, function, and control of neutrophil proteinases. Am J Med 1988;84(6A):37-42
-
(1988)
Am J Med
, vol.84
, Issue.6 A
, pp. 37-42
-
-
Travis, J.1
-
47
-
-
0033056463
-
The cell biology of leukocyte-mediated proteolysis
-
Owen CA, Campbell EJ. The cell biology of leukocyte-mediated proteolysis. J Leuk Biol 1999;65(2):137-50
-
(1999)
J Leuk Biol
, vol.65
, Issue.2
, pp. 137-150
-
-
Owen, C.A.1
Campbell, E.J.2
-
48
-
-
84942141160
-
CARM1 regulates alveolar epithelial senescence and elastase-induced emphysema susceptibility
-
[Epub ahead of print]
-
Sarker RS, John-Schuster G, Bohla A, et al. CARM1 regulates alveolar epithelial senescence and elastase-induced emphysema susceptibility. Am J Respir Cell Molecul Biol 2015. [Epub ahead of print]
-
(2015)
Am J Respir Cell Molecul Biol
-
-
Sarker, R.S.1
John-Schuster, G.2
Bohla, A.3
-
49
-
-
84921415291
-
Ezrin/Exocyst complex regulates mucin 5AC secretion induced by neutrophil elastase in human airway epithelial cells
-
Li Q, Li N, Liu CY, et al. Ezrin/Exocyst complex regulates mucin 5AC secretion induced by neutrophil elastase in human airway epithelial cells. Cell Physiol Biochem 2015;35(1):326-38
-
(2015)
Cell Physiol Biochem
, vol.35
, Issue.1
, pp. 326-338
-
-
Li, Q.1
Li, N.2
Liu, C.Y.3
-
50
-
-
28144447727
-
Comparative effects of salmeterol, albuterol, and ipratropium on normal and impaired mucociliary function in sheep
-
Sabater JR, Lee TA, Abraham WM. Comparative effects of salmeterol, albuterol, and ipratropium on normal and impaired mucociliary function in sheep. Chest 2005;128(5):3743-9
-
(2005)
Chest
, vol.128
, Issue.5
, pp. 3743-3749
-
-
Sabater, J.R.1
Lee, T.A.2
Abraham, W.M.3
-
51
-
-
4544235764
-
Augmentation therapy for alpha(1)-antitrypsin deficiency
-
Juvelekian GS, Stoller JK. Augmentation therapy for alpha(1)-antitrypsin deficiency. Drugs 2004;64(16):1743-56
-
(2004)
Drugs
, vol.64
, Issue.16
, pp. 1743-1756
-
-
Juvelekian, G.S.1
Stoller, J.K.2
-
52
-
-
84923115199
-
Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3
-
Hwang TL, Wang WH, Wang TY, et al. Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3. Bioorg Med Chem 2015;23(5):1123-34
-
(2015)
Bioorg Med Chem
, vol.23
, Issue.5
, pp. 1123-1134
-
-
Hwang, T.L.1
Wang, W.H.2
Wang, T.Y.3
-
53
-
-
84929209754
-
Sirtinol inhibits neutrophil elastase activity and attenuates lipopolysaccharide-mediated acute lung injury in mice
-
Tsai YF, Yu HP, Chang WY, et al. Sirtinol inhibits neutrophil elastase activity and attenuates lipopolysaccharide-mediated acute lung injury in mice. Scientific Reports 2015;5:8347
-
(2015)
Scientific Reports
, vol.5
, pp. 8347
-
-
Tsai, Y.F.1
Yu, H.P.2
Chang, W.Y.3
-
54
-
-
0036800045
-
Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in Guinea pigs
-
Wright JL, Farmer SG, Churg A. Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs. Am J Respir Crit Care Med 2002;166(7):954-60
-
(2002)
Am J Respir Crit Care Med
, vol.166
, Issue.7
, pp. 954-960
-
-
Wright, J.L.1
Farmer, S.G.2
Churg, A.3
-
55
-
-
78650096176
-
Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases
-
Korkmaz B, Horwitz MS, Jenne DE, Gauthier F. Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases. Pharmacol Rev 2010;62(4):726-59.
-
(2010)
Pharmacol Rev
, vol.62
, Issue.4
, pp. 726-759
-
-
Korkmaz, B.1
Horwitz, M.S.2
Jenne, D.E.3
Gauthier, F.4
-
58
-
-
70350059832
-
Potent inhibitors of beta-tryptase and human leukocyte elastase based on the MCoTIII scaffold
-
Thongyoo P, Bonomelli C, Leatherbarrow RJ, Tate EW. Potent inhibitors of beta-tryptase and human leukocyte elastase based on the MCoTIII scaffold. J Med Chem 2009;52(20):6197-200
-
(2009)
J Med Chem
, vol.52
, Issue.20
, pp. 6197-6200
-
-
Thongyoo, P.1
Bonomelli, C.2
Leatherbarrow, R.J.3
Tate, E.W.4
-
59
-
-
0022404962
-
Plasminogen activation and regulation of pericellular proteolysis
-
Saksela O. Plasminogen activation and regulation of pericellular proteolysis. Biochimica et Biophysica Acta 1985;823(1):35-65
-
(1985)
Biochimica et Biophysica Acta
, vol.823
, Issue.1
, pp. 35-65
-
-
Saksela, O.1
-
61
-
-
0030780354
-
Biochemical and pharmacological characterization of FK706, a novel elastase inhibitor
-
Shinguh Y, Imai K, Yamazaki A, et al. Biochemical and pharmacological characterization of FK706, a novel elastase inhibitor. Eur J Pharmacol 1997;337(1):63-71
-
(1997)
Eur J Pharmacol
, vol.337
, Issue.1
, pp. 63-71
-
-
Shinguh, Y.1
Imai, K.2
Yamazaki, A.3
-
62
-
-
0025767185
-
ONO-5046, a novel inhibitor of human neutrophil elastase
-
Kawabata K, Suzuki M, Sugitani M, et al. ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem Biophys Res Commun 1991;177(2):814-20
-
(1991)
Biochem Biophys Res Commun
, vol.177
, Issue.2
, pp. 814-820
-
-
Kawabata, K.1
Suzuki, M.2
Sugitani, M.3
-
63
-
-
9244264382
-
Impaired activity of protease inhibitors towards neutrophil elastase bound to human articular cartilage
-
Kawabata K, Moore AR, Willoughby DA. Impaired activity of protease inhibitors towards neutrophil elastase bound to human articular cartilage. Ann Rheum Dis 1996;55(4):248-52
-
(1996)
Ann Rheum Dis
, vol.55
, Issue.4
, pp. 248-252
-
-
Kawabata, K.1
Moore, A.R.2
Willoughby, D.A.3
-
64
-
-
33747172257
-
Pretreatment of sivelestat sodium hydrate improves the lung microcirculation and alveolar damage in lipopolysaccharideinduced acute lung inflammation in hamsters
-
Iba T, Kidokoro A, Fukunaga M, et al. Pretreatment of sivelestat sodium hydrate improves the lung microcirculation and alveolar damage in lipopolysaccharideinduced acute lung inflammation in hamsters. Shock 2006;26(1):95-8
-
(2006)
Shock
, vol.26
, Issue.1
, pp. 95-98
-
-
Iba, T.1
Kidokoro, A.2
Fukunaga, M.3
-
65
-
-
84942088426
-
A greener chemistry approach for synthesis of 4-(4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4 tetrahydropyrimidine-5-carboxylic acid ethyl ester
-
Jagwani D, Joshi P. A greener chemistry approach for synthesis of 4-(4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4 tetrahydropyrimidine-5-carboxylic acid ethyl ester. Int J Pharmaceut Sci Res 2015;6(2):783-90
-
(2015)
Int J Pharmaceut Sci Res
, vol.6
, Issue.2
, pp. 783-790
-
-
Jagwani, D.1
Joshi, P.2
-
66
-
-
79958071674
-
Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor
-
Hansen G, Gielen-Haertwig H, Reinemer P, et al. Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor. J Mol Biol 2011;409(5):681-91
-
(2011)
J Mol Biol
, vol.409
, Issue.5
, pp. 681-691
-
-
Hansen, G.1
Gielen-Haertwig, H.2
Reinemer, P.3
-
81
-
-
77954349203
-
Synthesis and evaluation of benzoxazinone derivatives on activity of human neutrophil elastase and on hemorrhagic shock-induced lung injury in rats
-
Hsieh PW, Yu HP, Chang YJ, Hwang TL. Synthesis and evaluation of benzoxazinone derivatives on activity of human neutrophil elastase and on hemorrhagic shock-induced lung injury in rats. Eur J Med Chem 2010;45(7):3111-15
-
(2010)
Eur J Med Chem
, vol.45
, Issue.7
, pp. 3111-3115
-
-
Hsieh, P.W.1
Yu, H.P.2
Chang, Y.J.3
Hwang, T.L.4
-
82
-
-
67651102823
-
Synthesis and optimization of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase
-
Shreder KR, Cajica J, Du L, et al. Synthesis and optimization of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase. Bioor Med Chem Let 2009;19(16):4743-6
-
(2009)
Bioor Med Chem Let
, vol.19
, Issue.16
, pp. 4743-4746
-
-
Shreder, K.R.1
Cajica, J.2
Du, L.3
-
83
-
-
19544363236
-
The evaluation of 2,8-disubstituted benzoxazinone derivatives as antiinflammatory and anti-platelet aggregation agents
-
Hsieh PW, Hwang TL, Wu CC, et al. The evaluation of 2,8-disubstituted benzoxazinone derivatives as antiinflammatory and anti-platelet aggregation agents. Bioor Med Chem Let 2005;15(11):2786-9
-
(2005)
Bioor Med Chem Let
, vol.15
, Issue.11
, pp. 2786-2789
-
-
Hsieh, P.W.1
Hwang, T.L.2
Wu, C.C.3
-
84
-
-
14744287476
-
1,2,5-Thiadiazolidin-3-one 1,1-dioxidebased heterocyclic sulfides are potent inhibitors of human tryptase
-
Wong T, Groutas CS, Mohan S, et al. 1,2,5-Thiadiazolidin-3-one 1,1-dioxidebased heterocyclic sulfides are potent inhibitors of human tryptase. Arch Biochem Biophys 2005;436(1):1-7
-
(2005)
Arch Biochem Biophys
, vol.436
, Issue.1
, pp. 1-7
-
-
Wong, T.1
Groutas, C.S.2
Mohan, S.3
-
86
-
-
0028137226
-
Mechanism-based inhibition of human leukocyte elastase and cathepsin G by substituted dihydrouracils
-
Groutas WC, Huang H, Epp JB, et al. Mechanism-based inhibition of human leukocyte elastase and cathepsin G by substituted dihydrouracils. Biochim Biophys Acta 1994;1227(3):130-6
-
(1994)
Biochim Biophys Acta
, vol.1227
, Issue.3
, pp. 130-136
-
-
Groutas, W.C.1
Huang, H.2
Epp, J.B.3
-
88
-
-
0242329796
-
Structure and activity relationships of novel uracil derivatives as topical antiinflammatory agents
-
Isobe Y, Tobe M, Inoue Y, et al. Structure and activity relationships of novel uracil derivatives as topical antiinflammatory agents. Bioor Med Chem 2003;11(23):4933-40
-
(2003)
Bioor Med Chem
, vol.11
, Issue.23
, pp. 4933-4940
-
-
Isobe, Y.1
Tobe, M.2
Inoue, Y.3
-
89
-
-
0019245596
-
The synthesis and properties of some 5-substituted uracil derivatives
-
Walker RT, Jones AS, De Clercq E, et al. The synthesis and properties of some 5-substituted uracil derivatives. Nucleic Acids Symp Ser 1980(8):s95-102
-
(1980)
Nucleic Acids Symp ser
, Issue.8
, pp. s95-102
-
-
Walker, R.T.1
Jones, A.S.2
De Clercq, E.3
-
91
-
-
0028914722
-
Structural basis of substrate specificity in the serine proteases
-
Perona JJ, Craik CS. Structural basis of substrate specificity in the serine proteases. Protein Sci 1995;4(3):337-60
-
(1995)
Protein Sci
, vol.4
, Issue.3
, pp. 337-360
-
-
Perona, J.J.1
Craik, C.S.2
-
92
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann V, Reichard U, Goosmann C, et al. Neutrophil extracellular traps kill bacteria. Science 2004;303(5663):1532-5
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1532-1535
-
-
Brinkmann, V.1
Reichard, U.2
Goosmann, C.3
-
93
-
-
79955647642
-
Neutrophil extracellular traps
-
Amulic B, Hayes G. Neutrophil extracellular traps. Cur Biol 2011;21(9):R297-8
-
(2011)
Cur Biol
, vol.21
, Issue.9
, pp. R297-R298
-
-
Amulic, B.1
Hayes, G.2
-
94
-
-
84885430741
-
Neutrophil extracellular traps (NETs)-formation and implications
-
Zawrotniak M, Rapala-Kozik M. Neutrophil extracellular traps (NETs)-formation and implications. Acta Biochim Pol 2013;60(3):277-84
-
(2013)
Acta Biochim Pol
, vol.60
, Issue.3
, pp. 277-284
-
-
Zawrotniak, M.1
Rapala-Kozik, M.2
-
95
-
-
78049496216
-
Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps
-
Papayannopoulos V, Metzler KD, Hakkim A, Zychlinsky A. Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps. J Cell Biol 2010;191(3):677-91
-
(2010)
J Cell Biol
, vol.191
, Issue.3
, pp. 677-691
-
-
Papayannopoulos, V.1
Metzler, K.D.2
Hakkim, A.3
Zychlinsky, A.4
-
96
-
-
84908135568
-
Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens
-
Branzk N, Lubojemska A, Hardison SE, et al. Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. Nat Immunol 2014;15(11):1017-25
-
(2014)
Nat Immunol
, vol.15
, Issue.11
, pp. 1017-1025
-
-
Branzk, N.1
Lubojemska, A.2
Hardison, S.E.3
-
97
-
-
78449308457
-
Epidemiology of invasive candidiasis
-
Arendrup MC. Epidemiology of invasive candidiasis. Curr Opin Crit Care 2010;16(5):445-52
-
(2010)
Curr Opin Crit Care
, vol.16
, Issue.5
, pp. 445-452
-
-
Arendrup, M.C.1
-
98
-
-
79960088199
-
Emerging fungal infections in immunocompromised patients
-
Low CY, Rotstein C. Emerging fungal infections in immunocompromised patients. F1000 Med Repor 2011;3:14
-
(2011)
F1000 Med Repor
, vol.3
, pp. 14
-
-
Low, C.Y.1
Rotstein, C.2
-
99
-
-
84879081253
-
NETosis and NADPH oxidase: At the intersection of host defense, inflammation, and injury
-
Almyroudis NG, Grimm MJ, Davidson BA, et al. NETosis and NADPH oxidase: at the intersection of host defense, inflammation, and injury. Front Immunol 2013;4:45
-
(2013)
Front Immunol
, vol.4
, pp. 45
-
-
Almyroudis, N.G.1
Grimm, M.J.2
Davidson, B.A.3
-
100
-
-
84879687648
-
Modulation of neutrophil NETosis: Interplay between infectious agents and underlying host physiology
-
Hahn S, Giaglis S, Chowdhury CS, et al. Modulation of neutrophil NETosis: interplay between infectious agents and underlying host physiology. Semin Immunopathol 2013;35(4):439-53
-
(2013)
Semin Immunopathol
, vol.35
, Issue.4
, pp. 439-453
-
-
Hahn, S.1
Giaglis, S.2
Chowdhury, C.S.3
-
102
-
-
84901336172
-
New aspects on the structure of neutrophil extracellular traps from chronic obstructive pulmonary disease and in vitro generation
-
Obermayer A, Stoiber W, Krautgartner WD, et al. New aspects on the structure of neutrophil extracellular traps from chronic obstructive pulmonary disease and in vitro generation. PLoS One 2014;9(5):e97784
-
(2014)
PLoS One
, vol.9
, Issue.5
-
-
Obermayer, A.1
Stoiber, W.2
Krautgartner, W.D.3
-
103
-
-
84902536600
-
NET formation induced by Pseudomonas aeruginosa cystic fibrosis isolates measured as release of myeloperoxidase-DNA and neutrophil elastase-DNA complexes
-
Yoo DG, Floyd M, Winn M, et al. NET formation induced by Pseudomonas aeruginosa cystic fibrosis isolates measured as release of myeloperoxidase-DNA and neutrophil elastase-DNA complexes. Immunol Lett 2014;160(2):186-94
-
(2014)
Immunol Lett
, vol.160
, Issue.2
, pp. 186-194
-
-
Yoo, D.G.1
Floyd, M.2
Winn, M.3
-
104
-
-
84879688494
-
Molecular mechanisms regulating NETosis in infection and disease
-
Branzk N, Papayannopoulos V. Molecular mechanisms regulating NETosis in infection and disease. Semin Immunopathol 2013;35(4):513-30
-
(2013)
Semin Immunopathol
, vol.35
, Issue.4
, pp. 513-530
-
-
Branzk, N.1
Papayannopoulos, V.2
-
105
-
-
84903755667
-
Interplay of infections, autoimmunity, and immunosuppression in systemic lupus erythematosus
-
Caza T, Oaks Z, Perl A. Interplay of infections, autoimmunity, and immunosuppression in systemic lupus erythematosus. Int Rev Immunol 2014;33(4):330-63
-
(2014)
Int Rev Immunol
, vol.33
, Issue.4
, pp. 330-363
-
-
Caza, T.1
Oaks, Z.2
Perl, A.3
|