Integrated isotope-assisted metabolomics and 13C metabolic flux analysis reveals metabolic flux redistribution for high glucoamylase production by Aspergillus niger

Microbial Cell Factories

Volumn 14, Issue 1, 2015, Pages

  Lu, Hongzhong ^a   Liu, Xiaoyun ^a   Huang, Mingzhi ^a   Xia, Jianye ^a   Chu, Ju ^a   Zhuang, Yingping ^a   Zhang, Siliang ^a   Noorman, Henk ^b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b DSM BIOTECHNOLOGY CENTER   (Netherlands)

Author keywords

13C metabolic flux analysis; Aspergillus niger; Cofactor metabolism; Glucoamylase; Metabolomics

Indexed keywords

CARBON 13; CITRIC ACID; GLUCAN 1,4 ALPHA GLUCOSIDASE; OXALIC ACID; PENTOSE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; AMINO ACID; CARBON;

ARTICLE; ASPERGILLUS NIGER; CARBON METABOLISM; CELL GROWTH; CONTROLLED STUDY; ENZYME LOCALIZATION; ENZYME SYNTHESIS; FUNGAL STRAIN; GLUCOSE TRANSPORT; METABOLIC FLUX ANALYSIS; METABOLITE; METABOLOMICS; NONHUMAN; OXIDATION REDUCTION STATE; PHENOTYPE; SIGNAL TRANSDUCTION; WILD TYPE; BIOMASS; CHEMISTRY; CITRIC ACID CYCLE; ENERGY METABOLISM; GENETICS; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION;

AMINO ACIDS; ASPERGILLUS NIGER; BIOMASS; CARBON ISOTOPES; CITRIC ACID CYCLE; ENERGY METABOLISM; GLUCAN 1,4-ALPHA-GLUCOSIDASE; KINETICS; METABOLIC FLUX ANALYSIS; METABOLOMICS; OXIDATION-REDUCTION;

EID: 84942022940     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-015-0329-y     Document Type: Article

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