TAK1 inhibition-induced RIP1-dependent apoptosis in murine macrophages relies on constitutive TNF-α signaling and ROS production

Journal of Biomedical Science

Volumn 22, Issue 1, 2015, Pages

  Wang, Jang Shiun ^a,b   Wu, Dean ^c   Huang, Duen Yi ^a   Lin, Wan Wan ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Macrophages; RIP1; ROS; TAK1; TNF

Indexed keywords

7 OXOZEAENOL; CASPASE; ETANERCEPT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; NATURAL PRODUCT; NECROSTATIN 1; NEUTRALIZING ANTIBODY; PROTEIN INHIBITOR; PROTEIN RIP1; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; UNCLASSIFIED DRUG; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; RALBP1 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; BONE MARROW DERIVED MACROPHAGE; CANCER CELL LINE; CAPILLARY ENDOTHELIAL CELL; CELL DEATH; CELL FATE; CELL MEDIATED CYTOTOXICITY; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; EPIDERMIS CELL; HUMAN; HUMAN CELL; KERATINOCYTE; MACROPHAGE; MICROGLIA; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MONOCYTE; MTT ASSAY; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RETINA PIGMENT CELL; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; GENETICS; HELA CELL LINE; IMMUNOLOGY; MOUSE;

ANIMALS; APOPTOSIS; GTPASE-ACTIVATING PROTEINS; HELA CELLS; HUMANS; MACROPHAGES; MAP KINASE KINASE KINASES; MICE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84941911317     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/s12929-015-0182-7     Document Type: Article

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