Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 6, 2012, Pages

  Wang, Yanyan ^a   Huang, Gonghua ^a   Vogel, Peter ^a   Neale, Geoffrey ^a   Reizis, Boris ^b   Chi, Hongbo ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Immune tolerance; Innate immunity

Indexed keywords

CD103 ANTIGEN; CD40 ANTIGEN; CD8 ANTIGEN; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE B; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR FOXO; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CD8+ T LYMPHOCYTE; CELL CYCLE CHECKPOINT; CELL EXPANSION; CELL MATURATION; CELL PROLIFERATION; CELL SUBPOPULATION; CELL SURVIVAL; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVATION; GENE EXPRESSION; HOMEOSTASIS; IMMUNOREGULATION; INTRACELLULAR SIGNALING; LYMPHOID CELL; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; STEM CELL; T LYMPHOCYTE ACTIVATION;

ANIMALS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELL SURVIVAL; CROSS-PRIMING; DENDRITIC CELLS; GENE DELETION; HOMEOSTASIS; MAP KINASE KINASE KINASES; MICE; MICE, INBRED C57BL; MYELOID CELLS; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY;

EID: 84863119109     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115635109     Document Type: Article

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