RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy

International Immunopharmacology

Volumn 14, Issue 4, 2012, Pages 674-682

  Ye, Yuan Chao ^a   Wang, Hong Ju ^a   Yu, Lu ^a   Tashiro, Shin Ichi ^b   Onodera, Satoshi ^b   Ikejima, Takashi ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Autophagy; Cytochrome c; Mitochondrial dysfunction; Necroptosis; Reactive oxygen species; TNF

Indexed keywords

3 METHYLADENINE; ADAPTOR PROTEIN; ANTIMYCIN A1; CYTOCHROME C; REACTIVE OXYGEN METABOLITE; ROTENONE; SERINE THREONINE KINASE RECEPTOR INTERACTING PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FIBROSARCOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR MECHANICS; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANTIMYCIN A; AUTOPHAGY; CELL LINE, TUMOR; CYTOCHROMES C; FIBROBLASTS; GENE EXPRESSION REGULATION; GTPASE-ACTIVATING PROTEINS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; ROTENONE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84868236208     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.08.003     Document Type: Article

References (36)

1. A. Degterev, Z. Huang, M. Boyce, Y. Li, P. Jagtap, and N. Mizushima Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury Nat Chem Biol 1 2 2005 112 119
2. W. Declercq, T. Vanden Berghe, and P. Vandenabeele RIP kinases at the crossroads of cell death and survival Cell 138 2 2009 229 232
3. A. Degterev, J. Hitomi, M. Germscheid, I.L. Ch'en, O. Korkina, and X. Teng Identification of RIP1 kinase as a specific cellular target of necrostatins Nat Chem Biol 4 5 2008 313 321
4. C. Gunther, E. Martini, N. Wittkopf, K. Amann, B. Weigmann, and H. Neumann Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis Nature 477 7338 2011 335 339
5. A. Oberst, C.P. Dillon, R. Weinlich, L.L. McCormick, P. Fitzgerald, and C. Pop Catalytic activity of caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis Nature 471 7338 2011 363 367
6. M.E. Peter Programmed cell death: apoptosis meets necrosis Nature 471 7338 2011 310 312
7. P.S. Welz, A. Wullaert, K. Vlantis, V. Kondylis, V. Fernandez-Majada, and M. Ermolaeva FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation Nature 477 7338 2011 330 334
8. B. Levine, and J. Yuan Autophagy in cell death: an innocent convict? J Clin Invest 115 10 2005 2679-2288
9. W. Martinet, P. Agostinis, B. Vanhoecke, M. Dewaele, and G.R. De Meyer Autophagy in disease: a double-edged sword with therapeutic potential Clin Sci (Lond) 116 9 2009 697 712
10. A. Lleo, P. Invernizzi, C. Selmi, R.L. Coppel, G. Alpini, and M. Podda Autophagy: highlighting a novel player in the autoimmunity scenario J Autoimmun 29 2-3 2007 61 68
11. Y. Kabeya, N. Mizushima, T. Ueno, A. Yamamoto, T. Kirisako, and T. Noda LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing EMBO J 19 21 2000 5720 5728
12. G. Chen, F. Wang, D. Trachootham, and P. Huang Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds Mitochondrion 10 6 2010 514 625
13. A.K. Camara, E.J. Lesnefsky, and D.F. Stowe Potential therapeutic benefits of strategies directed to mitochondria Antioxid Redox Signal 13 3 2010 279 347
14. D. Trachootham, W. Lu, M.A. Ogasawara, R.D. Nilsa, and P. Huang Redox regulation of cell survival Antioxid Redox Signal 10 8 2008 1343 1374
15. V. Goossens, G. Stange, K. Moens, D. Pipeleers, and J. Grooten Regulation of tumor necrosis factor-induced, mitochondria- and reactive oxygen species-dependent cell death by the electron flux through the electron transport chain complex I Antioxid Redox Signal 1 3 1999 285 295
16. Y.C. Ye, L. Yu, H.J. Wang, S. Tashiro, S. Onodera, and T. Ikejima TNFα-induced necroptosis and autophagy via supression of p38-NF-κB survival pathway in L929 cells J Pharmacol Sci 117 3 2011 160 169
17. E. Eruslanov, and S. Kusmartsev Identification of ROS using oxidized DCFDA and flow-cytometry Methods Mol Biol 594 2010 57 72
18. R. Zhou, A.S. Yazdi, P. Menu, and J. Tschopp A role for mitochondria in NLRP3 inflammasome activation Nature 469 7329 2011 221 225
19. A.C. Rego, S. Vesce, and D.G. Nicholls The mechanism of mitochondrial membrane potential retention following release of cytochrome c in apoptotic GT1-7 neural cells Cell Death Differ 8 10 2001 995 1003
20. D.F. Stowe, and A.K. Camara Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function Antioxid Redox Signal 11 6 2009 1373 1414
21. P. Vandenabeele, L. Galluzzi, T. Vanden Berghe, and G. Kroemer Molecular mechanisms of necroptosis: an ordered cellular explosion Nat Rev Mol Cell Biol 11 10 2010 700 714
22. M. Bras, V.J. Yuste, G. Roue, S. Barbier, P. Sancho, and C. Virely Drp1 mediates caspase-independent type III cell death in normal and leukemic cells Mol Cell Biol 27 20 2007 7073 7088
23. A. Laurent, C. Nicco, C. Chereau, C. Goulvestre, J. Alexandre, and A. Alves Controlling tumor growth by modulating endogenous production of reactive oxygen species Cancer Res 65 3 2005 948 956
24. R.J. Thapa, S.H. Basagoudanavar, S. Nogusa, K. Irrinki, K. Mallilankaraman, and M.J. Slifker NF-kappaB protects cells from gamma interferon-induced RIP1-dependent necroptosis Mol Cell Biol 31 14 2011 2934 2946
25. P. Vanlangenakker, T. Vanden Berghe, P. Bogaert, B. Laukens, K. Zobel, and K. Deshayes cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production Cell Death Differ 18 4 2011 656 665
26. L. Moretti, K.W. Kim, D.K. Jung, C.D. Willey, and B. Lu Radiosensitization of solid tumors by Z-VAD, a pan-caspase inhibitor Mol Cancer Ther 8 5 2009 1270 1279
27. A.R. King, S.E. Francis, C.J. Bridgeman, H. Bird, M.K. Whyte, and D.C. Crossman A role for caspase-1 in serum withdrawal-induced apoptosis of endothelial cells Lab Invest 83 10 2003 1497 1508
28. N. Mori, A. Yasutake, M. Marumoto, and K. Hirayama Methylmercury inhibits electron transport chain activity and induces cytochrome c release in cerebellum mitochondria J Toxicol Sci 36 3 2011 253 259
29. J. Radhakrishnan, S. Wang, I.M. Ayoub, J.D. Kolarova, R.F. Levine, and R.J. Gazmuri Circulating levels of cytochrome c after resuscitation from cardiac arrest: a marker of mitochondrial injury and predictor of survival Am J Physiol Heart Circ Physiol 292 2 2007 H767 H775
30. G. Yang, L. Wu, S. Chen, L. Zhu, P. Huang, and L. Tong Mitochondrial dysfunction resulting from loss of cytochrome c impairs radiation-induced bystander effect Br J Cancer 100 12 2009 1912 1916
31. R.A. Zager, A.C. Johnson, and S.Y. Hanson Proximal tubular cytochrome c efflux: determinant, and potential marker, of mitochondrial injury Kidney Int 65 6 2004 2123 2134
32. J.C. Martinou, and D.R. Green Breaking the mitochondrial barrier Nat Rev Mol Cell Biol 2 1 2001 63 67
33. V. Temkin, Q.Q. Huang, H.T. Liu, H. Osada, and R.M. Pope Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis Mol Cell Biol 26 6 2006 2215 2225
34. A.K. Samraj, D. Sohn, K. Schulze-Osthoff, and I. Schmitz Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization Mol Biol Cell 18 1 2007 84 93
35. H. Endo, H. Kamada, C. Nito, T. Nishi, and P.H. Chan Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats J Neurosci 26 30 2006 7974 7983
36. H.C. Tu, D. Ren, G.X. Wang, D.Y. Chen, T.D. Westergard, and H. Kim The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage Proc Natl Acad Sci U S A 106 4 2009 1093 1098