Deletion of TAK1 in the Myeloid Lineage Results in the Spontaneous Development of Myelomonocytic Leukemia in Mice

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Lamothe, Betty ^a   Lai, YunJu ^a   Hur, Lana ^a   Orozco, Natalia Martin ^a   Wang, Jing ^a   Campos, Alejandro D ^a   Xie, Min ^b   Schneider, Michael D ^c   Lockworth, Cynthia R ^a   Jakacky, Jared ^a   Tran, Diep ^a   Ho, Michael ^a   Dawud, Sity ^a   Dong, Chen ^a   Lin, Hui Kuan ^a   Hu, Peter ^a   Estrov, Zeev ^a   Bueso Ramos, Carlos E ^a   Darnay, Bryant G ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR 1;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL EXPANSION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE; GENE DELETION; GENOMIC INSTABILITY; HUMAN; LEUKEMOGENESIS; MALE; MOUSE; MYELOMONOCYTIC LEUKEMIA; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; TAK1 GENE;

ANIMALS; CYTOKINES; FLOW CYTOMETRY; GENE DELETION; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LEUKEMIA, MYELOMONOCYTIC, ACUTE; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SPLENOMEGALY;

MUS;

EID: 84870922929     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051228     Document Type: Article

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