Improved functional characteristics of whey protein hydrolysates in food industry

Korean Journal for Food Science of Animal Resources

Volumn 35, Issue 3, 2015, Pages 350-359

  Jeewanthi, Renda Kankanamge Chaturika ^a   Lee, Na Kyoung ^a   Paik, Hyun Dong ^a  

^a Konkuk University   (South Korea)

Author keywords

Enzymatic hydrolysis; Food application; Functionality; Whey protein; Whey protein hydrolysate

Indexed keywords

EID: 84941651166     PISSN: 12258563     EISSN: None     Source Type: Journal    
DOI: 10.5851/kosfa.2015.35.3.350     Document Type: Article

References (95)

1. Adler-Nissen, J. (1986) A Review of Food Protein Hydrolysis Specific Areas. In: Enzymatic hydrolysis of food proteins, Elsevier, London, England, pp. 57-109.
2. Agboola, S. O., Singh, H., Munro, P., Dalglesh, D. G., and Singh, A. M. (1998) Destabilization of oil-in-water emulsions formed using highly hydrolysed whey proteins. J. Agric. Food Chem. 46, 84-90.
3. Athira, S., Mann, B., Saini, P., Sharma, R., Kumar, R., and Singh, A. K. (2014) Production and characterisation of whey protein hydrolysates having antioxidant activity from cheese whey. J. Sci. Food Agri. DOI 10.1002/jsfa.7032.
4. Barbut, S. (2007) Effect of hydrolyzed and regular dairy proteins on the texture, colour and microstructure of poultry meat emulsions. Br. Poult. Sci. 48, 655-660.
5. Bouaouina, H., Desrumaux, A., Loisel, C., and Legrand, J. (2006) Functional properties of whey proteins as affected by dynamic high pressure treatment. Int. Dairy J. 16, 275-284.
6. Bryant, C. and McClements, D. J. (1998) Molecular basis of cold-setting whey protein ingredients. Trends Food Sci. Technol. 9, 143-151.
7. Burrington, K. (1999) Whey products in baked goods applications monograph - Bakery. U.S. Dairy Export Council. USA. eA2.1- eA2.8.
8. Creusot, N. and Gruppen, H. (2007a) Enzyme-induced aggregation and gelation of proteins. Biotech. Adv. 25, 597-601.
9. Creusot, N. and Gruppen, H. (2007b) Protein peptide interactions in mixtures of whey peptides and whey proteins. J. Agric. Food Chem. 55, 2474-2481.
10. Creusot, N. and Gruppen, H. (2008) Hydrolysis of whey protein isolate with Bacillus licheniformis protease: Aggregating capacities of peptide fractions. J. Agric. Food Chem. 56, 10332-10339.
11. Creusot, N., Gruppen, H., Van Koningsveld, G. A., De Kruif, C. G., and Vorgen, A. G. J. (2006) Peptide-peptide and protein- peptide interactions in mixtures of whey protein isolate and whey protein isolate hydrolysates. Int. Dairy J. 16, 840-849.
12. Davis, J. P., Doucet, D., and Foegeding, E. A. (2005) Foaming and interfacial properties of hydrolyzed β-lactoglobulin. J. Colloid Interface Sci. 288, 412-422.
13. de Wit, J. N. (1998) Nutritional and functional characteristics of whey protein in food products. J. Dairy Sci. 81, 597-608.
14. Decher, G. (1997) Fuzzy nanoassemblies: Toward layered polymeric multi-composites. Science 277, 1232-1237.
15. Doucet, D. and Foegeding, E. A. (2005) Gel formation of peptides produced by extensive enzymatic hydrolysis of β- lactoglobulin. Biomacromolecules 6, 1140-1148.
16. Doucet, D., Gauthier, S. F., and Foegeding, E. A. (2001) Rheological characterization of a gel formed during extensive enzymatic hydrolysis. J. Food Sci. 66, 711-715.
17. Doucet, D., Gauthier, S. F., Otter, D. E., and Foegeding, E. A. (2003a) Enzyme-induced gelation of extensively hydrolyzed whey proteins by alcalase: Comparison with the plastein reaction and characterization interactions. J. Agric. Food Chem. 51, 6036-6042.
18. Doucet, D., Otter, D. E., Gauthier, S. F., and Foegeding, E. A. (2003b) Enzyme-induced gelation of extensively hydrolyzed whey proteins by alcalase: Peptide identification and determination of enzyme specificity. J. Agric. Food Chem. 51, 6300-6308.
19. Drake, M. A., Miracle, R. E., and Wright, J. M. (2009) Sensory Properties of Dairy Proteins. In: Milk proteins from expression to food. Thompson, A., Boland, M., and Singh, H. (eds) Elsevier, Amsterdam, The Netherlands. pp. 429-448.
20. Flanagan, J. and FitzGerald, R. J. (2002) Physicochemical and nitrogen solubility properties of Bacillus proteinase hydrolysates of sodium caseinate incubated with transglutaminase preand post-hydrolysis. J. Agric. Food Chem. 50, 5429-5436.
21. Foegeding, E. A., Davis, J. P., Doucet, D., and McGuffey, M. K. (2002) Advances in modifying and understanding whey protein functionally. Trends Food Sci. Tech.13, 151-159.
22. Francis, F. J. and Wiley R. H. (2000) Whey: Composition, Properties, Processing and Uses. In: Wiley encyclopedia of food science and technology. 2nd Edition. New York, NY. pp. 2652-2661.
23. Gauthier, S. F., Paquin, P., Pouliot, Y., and Turgeon, S. (1993) Surface activity and related functional properties of peptides obtained from whey proteins. J. Dairy Sci. 76, 321-328.
24. Goode, K. R., Bowen, J., Akhtar, N., Robbins, P. T., and Fryer, P. J. (2013) The effect of temperature on adhesion forces between surfaces and model foods containing whey protein and sugar. J. Food Eng. 118, 371-379.
25. Groleau, P. E., Gauthier, S. F., and Pouliot, Y. (2003a) Effect of residual chymotryptic activity in a trypsin preparation on peptide aggregation in a β-lactoglobulin hydrolysate. Int. Dairy J. 13, 887-895.
26. Groleau, P. E., Morin, P., Gauthier, S. F., and Pouliot, Y. (2003b) Effect of physicochemical conditions on peptide-peptide interactions in a tryptic hydrolysate of β-lactoglobulin and intensification of aggregating peptides. J. Agric. Food Chem. 51, 4370-4375.
27. Guzey, D. and McClements, D. J. (2006) Formation, stability and properties of multilayer emulsions for application in the food industry. Adv. Colloid Interface Sci. 128, 227-248.
28. Huang, X. L., Catignani, G. L., and Swaisgood, H. E. (1999) Modication of rheological properties of whey protein isolates by limited proteolysis. Nahrung 43, 79-85.
29. Innocente, N., Corradini, C., Blecker, C., and Paquot, M. (1998) Dynamic surface tension properties of the proteosepeptone fraction of bovine milk. J. Dairy Sci. 81, 1833-1839.
30. Ipsen, R., Otte, J., Lomholt, S. T., and Qvist, K. B. (2000) Standardized reaction times used to describe the mechanism of enzyme-induced gelation in whey protein systems. J. Dairy Res. 67, 403-413.
31. Ipsen, R., Otte, J., and Schumacher, E. (1997) Controlled stress rheometry compared with Formagraph measurements for characterization of the enzyme induced gelation of whey proteins at various pH. Ann. Trans. Nordic Rheology Society 5, 48-50.
32. Jeewanthi, R. K. C., Paik, H. D., Kim, M. H., Lee, N. K., Kim, S. Y., and Yoon, Y. C. (2014) Characteristics of whey protein hydrolysates from cheese whey, favors on various food applications. Chem. Ind. Chem. Eng. Q. 20, 503-509.
33. Ju, Z. Y. and Kilara, A. (1998) Gelation of pH-aggregated whey protein isolate solution induced by heat, protease, calcium salt, and acidulant. J. Agric. Food Chem. 46, 1830-1835.
34. Ju, Z. Y., Otte, J., Madsen, J. S., and Qvist, K. B. (1995) Effects of limited proteolysis on gelation and gel properties of whey protein isolate. J. Dairy Sci. 78, 2119-2128.
35. Kang, I. J., Matsumura, Y., Ikura, K., Motoki, M., Sakamoto, H., and Mori, T. (1994) Gelation and gel properties of soybean glycinin in a transglutaminase-catalyzed system. J. Agric. Food Chem. 42, 159-165.
36. Keaton, J. (1999) Whey protein and lactose products in processed meats, Applications monograph - Meat, Published by U.S. Dairy Export Council, eD2.1-eD2.8.
37. Kilara, A. and Panyam, D. (2003) Peptides from milk proteins and their properties. Crit. Rev. Food Sci. Nutr. 43, 607-633.
38. Kim, S. B., Seo, I. S., Khan, M. A., Ki, K. S., Lee, W. S., Lee, H. J., Shin, H. S., and Kim, H. S. (2007) Enzymatic hydrolysis of heated whey: Iron-binding ability of peptides and antigenic protein fractions. J. Dairy Sci. 90, 4033-4042.
39. Konrad, G., Kleinschmidt, T., Rohenkohl, H., and Reimerdes, E. H. (2005) Peptic partial hydrolysis of whey protein concentrate for modifying the surface properties of whey protein. II. Effects on the emulsifying and foaming properties. Milchwissenschaft 60, 195-198.
40. Kosikowski, F. V. (1979) Whey utilization and whey products. J. Dairy Sci. 62, 1149-1160.
41. Kresic, G. and Lelas, V. Herceg, Z., and Rezek, A. (2006) Effects of high pressure on functionality of whey protein concentrate and whey protein isolate. Lait 86, 303-315.
42. Kumar, S. K., Jayaprakasha, Manjappa H., Paik, H. D., Kim, S. K., Han, S. E., Jeong, A. R., and Yoon, Y. C. (2010) Production of ready-to-reconstitute functional beverages by utilizing whey protein hydrolysates and probiotics. Korean J. Food Sci. An. 30, 575-578.
43. Madsen, J. S., Ahmt, T. O., Otte, J., Halkier, T., and Qvist, K. B. (1997) Hydrolysis of β-lactoglobulin by four different proteinases monitored by capillary electrophoresis and high performance liquid chromatography. Int. Dairy J. 7, 399-409.
44. Mahmoud, M. I. (1994) Physicochemical and functional, properties of protein hydrolysates in nutritional products. Food Technol. 48, 89-95.
45. Majhi, P. R., Ganta, R. R., Vanam, R. P., Seyrek, E., Giger, K., and Dubin, P. L. (2006) Electrostatically driven protein aggregation: β-lactoglobulin at low ionic strength. Langmuir 22, 9150-9159.
46. Mann, E. J. (2000) Whey products and their uses. Dairy Ind. Int. 65, 13-14.
47. Mate, J. I. and Krochta, J. M. (1996) Comparison of oxygen and water vapor permeabilities of whey protein isolate and β- lactoglobulin edible films. J. Agric. Food Chem. 44, 3001-3004.
48. Matoba, T. and Hata, T. (1972) Relationship between bitterness of peptides and their chemical structures. Agric. Biol. Chem. 36, 1423-1431.
49. McHugh, T. H. and Krochta, J. M. (1994) Sorbitol-plasticized vs. glycerol-plasticized whey-protein edible films: Integrated oxygen permeability and tensile property evaluation. J. Agric. Food Chem. 42, 841-845.
50. Mehalebi, S., Nicolai, T., and Durand, D. (2008) Light scattering study of heat-denatured globular protein aggregates. Int. J. Biol. Macromol. 43, 129-135.
51. Miller, K. S., Chiang, M. T., and Krochta, J. M. (1997) Heat curing of edible whey protein films. J. Food Sci. 62, 1189-1193.
52. Morr, C. V. and Ha, E. Y. (1993) Whey protein concentrates and isolates: Processing and functional properties. Crit. Rev. Food Sci. Nutr. 33, 431-476.
53. Mutilangi, W. A. M., Panyam, D., and Kilara, A. (1996) Functional properties of hydrolysates from proteolysis of heat-denatured whey protein isolate. J. Food Sci. 61, 270-275.
54. Nakamura, T., Sado, H., Syukunobe, Y., and Hirata, T. (1993) Antigenicity of whey protein hydrolysates prepared by combination of two proteinases. Milchwissenschaft 48, 667-670.
55. Otte, J., Ju, Z. Y., Faergemand, M., Lomholt, S. B., and Qvist, K. B. (1996a) Protease-induced aggregation and gelation of whey proteins. J. Food Sci. 61, 911-923.
56. Otte, J., Ju, Z. Y., Skriver, A., and Qvist, K. B. (1996b) Effect of limited proteolysis on the microstructure of heat-induced whey protein gels at varying pH. J. Dairy Sci. 79, 782-790.
57. Otte, J., Schumacher, E., Ipsen, R., Ju, Z. Y., and Qvist, K. B. (1999) Protease-induced gelation of unheated and heated whey proteins: Effect of pH, temperature and concentrations of protein, enzyme and salts. Int. Dairy J. 9, 801-812.
58. Pelegrine, D. H. G. and Gasparetto, C. A. (2005) Whey proteins solubility as function of temperature and pH. LWT-Food Sci. Technol. 38, 77-80.
59. Pelegrine, D. H. G. and Gomes, M. T. M. S. (2012) Analysis of whey proteins solubility at high temperatures. Int. J. Food Eng. 3, 1556-3758.
60. Perea, A., Ugalde, U., Rodriguez, I., and Serra, J. L. (1993) Preparation and characterization of whey protein hydrolysates: Applications in industrial whey bioconversion processes. Enzyme Microb. Technol. 15, 418-423.
61. Perez-Gago, M. B. and Krochta, J. M. (2002) Formation and Properties of Whey Protein Films and Coatings. In: Protein-based films and coatings. Gennadios, A. (ed) CRC Press, Boca Raton, FL. pp.159-180.
62. Perez-Gago, M. B., Serra, M., and Del Río, M. A. (2006) Color change of fresh-cut apples coated with whey protein concentrate- based edible coatings. Postharvest Biol. Technol. 39, 84-92.
63. Pinterits, A. and Arnteld, S. D. (2007) The effect of limited proteolysis on canola protein gelation. Food Chem. 102, 1337-1343.
64. Pouliot, Y., Guy, M. M., Tremblay, M., Gaonac'h, A. C., Ting, B. P. C. P., Gauthier, S. F., and Voyer, N. (2009) Isolation and characterization of an aggregating peptide from a tryptic hydrolysate of whey proteins. J. Agric. Food Chem. 57, 3760-3764.
65. Prabhu, G. (2006) U.S. Whey protein in processed meats. Application monograph processed meats, U.S. Dairy Export Council. e-3-6-1- e-3-6-12.
66. Rabiey, L. and Britten, M. (2009a) Effect of protein composition on the rheological properties acid-induced whey protein gels. Food Hydrocolloids 23, 973-979.
67. Rabiey, L. and Britten, M. (2009b) Effect of whey protein enzymatic hydrolysis on the rheological properties acid-of acid induced whey protein gels. Food Hydrocolloids 23, 2302-2308.
68. Rinn, J. C., Morr, C. V., Seo, A., and Surak, J. G. (1990) Evaluation of nine semi-pilot scale whey protein pre-treatment modifications for providing whey protein concentrates. J. Food Sci. 55, 510-515.
69. Rios, G. M., Belleville, M. P., Paolucci, D., and Sanchez, J. (2004) Progress in enzymatic membrane reactors: A review. J. Membr. Sci. 242, 189-196.
70. Rocha, C., Teixeria, J. A., Hilliou, L., Sampaio, P., and Goncalves, M. P. (2009) Rheological and structural characterization of gels from whey protein hydrolysates/locust bean gum mixed systems. Food Hydrocolloids 23, 1734-1745.
71. Rullier, B., Axelos, M. A. V., Langevin, D., and Novales, B. (2010) β-lactoglobulin aggregates in foam films: Effect of the concentration and size of the protein aggregates. J. Colloid Interface Sci. 343, 330-337.
72. Schmid, M. (2013) Properties of cast films made from different ratios of whey protein isolate, hydrolysed whey protein isolate and glycerol, Materials 6, 3254-3269.
73. Schmid, M., Hinz, L. V., Wild, F., and Noller, K. (2013) Effects of hydrolysed whey proteins on the techno-functional characteristics of whey protein-based films. Materials 6, 927-940.
74. Schmitt, C., Bovay, C., Vuilliomenet, A., Rouvet, M., Bovetto, L., Barbar, R., and Sanchez, C. (2009) Multi-scale characterization of individualized β-lactoglobulin micro gels formed upon heat treatment under narrow pH range conditions. Langmuir 25, 7899-7909.
75. Sharma, S., Singh, R., and Rana, S. (2011) Bioactive peptides: Review, Int. J. Bioautomation 15, 223-250.
76. Sinha, R., Radha, C., Prakash, J., and Kaul, P. (2007) Whey protein hydrolysate: Functional properties, nutritional quality and utilization in beverage formulation. Food Chem. 101, 1484-1491.
77. Smith, K. (2004) Whey processing CDR technical review: Bleaching. Wisconsin Center for Dairy Research, Madison. pp. 1-17.
78. Smithers, G. W. (2008) Whey and whey proteins-from 'gutter- to-gold'. Int. Dairy J. 18, 695-704.
79. Sothornvit, R. and Krochta, J. M. (2000a) Oxygen permeability and mechanical properties of films from hydrolyzed whey protein. J. Agric. Food Chem. 48, 3913-3916.
80. Sothornvit, R. and Krochta, J. M. (2000b) Water vapor permeability and solubility of films from hydrolyzed whey protein. J. Food Sci. 65, 700-703.
81. Sousa, J. R. R., Lopes, G. P., Tardioli, P. W., Giordano, R. L. C., Almeida, P. I. F., and Giordano, R. C. (2004) Kinetic model for whey protein hydrolysis by alcalase multipoint-immobilized on agarose gel particles. Braz. J. Chem. Eng. 21, 147-153.
82. Spellman, D., Kenny, P., O'Cuinn, G., and FitzGerald, R. J. (2005) Aggregation properties of whey protein hydrolysates generated with Bacillus licheniformis proteinase activities. J. Agric. Food Chem. 5, 1258-1265.
83. Spellman, D., O'Cuinn, G., and FitzGerald, R. J. (2009) Bitterness in Bacillus proteinase hydrolysates of whey proteins. Food Chem.114, 440-446.
84. Suarez, E., San Martin, F., Alvarez, R., and Coca, J. (1992) Reverse osmosis of whey. Determination of mass transfer coefficients. J. Membr. Sci. 68, 301-305.
85. Tomaino, R. M., Turner, L. G., and Larick, D. K. (2004) The effect of Lactococcus lactis starter cultures on the oxidative stability of liquid whey. J. Dairy Sci. 87, 300-307.
86. Tsai, S. J., Unklesbay, N., Unklesbay, K., and Clarke, A. (1998) Water and absorption properties of restructured beef products with five binders at four isothermal temperatures. LWT-Food Sci. Technol. 31, 78-83.
87. Turgeon, S. L., Gauthier, S. F., and Paquin, P. (1991) Interfacial and emulsifying properties of whey fractions obtained with a two-step ultrafiltration process. J. Agric. Food Chem. 39, 673-676.
88. van der Ven, C., Gruppen, H., De Bont, D. B. A., and Voragen, A. G. J. (2002) Correlations between biochemical characteristics and foam-forming and stabilizing ability of whey and casein hydrolysates. J. Agric. Food Chem. 50, 2938-2946.
89. Voutsinas, L. P. and Nakai, S. (1983) A simple turbidimetric method for determining the fat binding capacity of proteins. J. Agric. Food Chem. 31, 58-59.
90. Wright, B. J., Zevchak, S. E., Wright, J. M., and Drake, M. A. (2009) The impact of agglomeration and storage on flavor and flavor stability of whey protein 80% and whey protein isolate. J. Food Sci. 74, 17-29.
91. Ye, A., Hemar, Y., and Singh, H. (2004) Flocculation and coalescence of droplets in oil-in-water emulsions formed with highly hydrolysed whey proteins as influenced by starch. Colloid. Surface. B. 38, 1-9.
92. Ye, A. and Singh, H. (2006) Heat stability of oil-in-water emulsions formed with intact or hydrolysed whey proteins: Influence of polysaccharides. Food Hydrocolloids 20, 269-276.
93. Yi, J. and Ding, Y. (2014) Dual effects of whey protein isolates on the inhibition of enzymatic browning and clarification of apple juice. Czech J. Food Sci. 32, 601-609.
94. Yoon, Y. C., An, S. I., Jeong, A. R., Han, S. E., Kim, M. H., and Lee, C. K. (2010) Characteristics of whey protein (WPC- 30) hydrolysates from cheese whey. J. Animal Sci. Tech. 52, 435-440.
95. Zhu, H. and Damodaran, S. (1994) Proteose-peptones and physical factors affect foaming properties of whey protein isolate. J. Food Sci. 59, 554-560.