-
1
-
-
85047692172
-
Therapeutic vaccines for cancer: An overview of clinical trials
-
Melero I, et al. Therapeutic vaccines for cancer: an overview of clinical trials. Nat Rev Clin Oncol. 2014;11(9):509-524.
-
(2014)
Nat Rev Clin Oncol
, vol.11
, Issue.9
, pp. 509-524
-
-
Melero, I.1
-
2
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366(26):2455-2465.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
-
3
-
-
45549092607
-
Cancer immunology
-
Finn OJ. Cancer immunology. N Engl J Med. 2008;358(25):2704-2715.
-
(2008)
N Engl J Med
, vol.358
, Issue.25
, pp. 2704-2715
-
-
Finn, O.J.1
-
4
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711-723.
-
(2011)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
-
5
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366(26):2443-2454.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
-
6
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med. 2013;369(2):122-133.
-
(2013)
N Engl J Med
, vol.369
, Issue.2
, pp. 122-133
-
-
Wolchok, J.D.1
-
7
-
-
80455179612
-
Safety and persistence of adoptively transferred autologous CD19-Targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
-
Brentjens RJ, et al. Safety and persistence of adoptively transferred autologous CD19-Targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood. 2011;118(18):4817-4828.
-
(2011)
Blood
, vol.118
, Issue.18
, pp. 4817-4828
-
-
Brentjens, R.J.1
-
8
-
-
84876005284
-
CD19-Targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
-
Brentjens RJ, et al. CD19-Targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med. 2013;5(177):177ra38.
-
(2013)
Sci Transl Med
, vol.5
, Issue.177
, pp. 177ra38
-
-
Brentjens, R.J.1
-
9
-
-
84908073316
-
Chimeric antigen receptor T cells for sustained remissions in leukemia
-
Maude SL, et al. Chimeric antigen receptor T cells for sustained remissions in leukemia. N Engl J Med. 2014;371(16):1507-1517.
-
(2014)
N Engl J Med
, vol.371
, Issue.16
, pp. 1507-1517
-
-
Maude, S.L.1
-
10
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med. 2011;365(8):725-733.
-
(2011)
N Engl J Med
, vol.365
, Issue.8
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
Bagg, A.4
June, C.H.5
-
11
-
-
77649221824
-
Long-Term outcome of EBVspecific T-cell infusions to prevent or treat EBVrelated lymphoproliferative disease in transplant recipients
-
Heslop HE, et al. Long-Term outcome of EBVspecific T-cell infusions to prevent or treat EBVrelated lymphoproliferative disease in transplant recipients. Blood. 2010;115(5):925-935.
-
(2011)
Blood
, vol.115
, Issue.5
, pp. 925-935
-
-
Heslop, H.E.1
-
12
-
-
84928912377
-
A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: Long-Term follow-up and correlates with response
-
Robbins PF, et al. A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-Term follow-up and correlates with response. Clin Cancer Res. 2014;21(5):1019-1027.
-
(2014)
Clin Cancer Res
, vol.21
, Issue.5
, pp. 1019-1027
-
-
Robbins, P.F.1
-
13
-
-
84879066944
-
Cancer vaccines targeting carcinoembryonic antigen: State-of-The-art and future promise
-
Gameiro SR, Jammeh ML, Hodge JW. Cancer vaccines targeting carcinoembryonic antigen: state-of-The-art and future promise. Expert Rev Vaccines. 2013;12(6):617-629.
-
(2013)
Expert Rev Vaccines
, vol.12
, Issue.6
, pp. 617-629
-
-
Gameiro, S.R.1
Jammeh, M.L.2
Hodge, J.W.3
-
14
-
-
84904621154
-
Engineering α-fetoprotein-based gene vaccines to prevent and treat hepatocellular carcinoma: Review and future prospects
-
He Y, Hong Y, Mizejewski GJ. Engineering α-fetoprotein-based gene vaccines to prevent and treat hepatocellular carcinoma: review and future prospects. Immunotherapy. 2014;6(6):725-736.
-
(2014)
Immunotherapy
, vol.6
, Issue.6
, pp. 725-736
-
-
He, Y.1
Hong, Y.2
Mizejewski, G.J.3
-
15
-
-
84863215164
-
Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients
-
Ohue Y, et al. Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients. Int J Cancer. 2012;131(5):E649-E658.
-
(2012)
Int J Cancer
, vol.131
, Issue.5
, pp. E649-E658
-
-
Ohue, Y.1
-
16
-
-
84902124061
-
Discovery of mesothelin and exploiting it as a target for immunotherapy
-
Pastan I, Hassan R. Discovery of mesothelin and exploiting it as a target for immunotherapy. Cancer Res. 2014;74(11):2907-2912.
-
(2014)
Cancer Res
, vol.74
, Issue.11
, pp. 2907-2912
-
-
Pastan, I.1
Hassan, R.2
-
17
-
-
0035182192
-
Efficient identification of novel HLA-A()0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis
-
Kessler JH, et al. Efficient identification of novel HLA-A()0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis. J Exp Med. 2001;193(1):73-88.
-
(2001)
J Exp Med
, vol.193
, Issue.1
, pp. 73-88
-
-
Kessler, J.H.1
-
18
-
-
84864935156
-
Vaccines in non-small cell lung cancer: Rationale, combination strategies and update on clinical trials
-
De Pas T, et al. Vaccines in non-small cell lung cancer: rationale, combination strategies and update on clinical trials. Crit Rev Oncol Hematol. 2012;83(3):432-443.
-
(2012)
Crit Rev Oncol Hematol
, vol.83
, Issue.3
, pp. 432-443
-
-
De Pas, T.1
-
19
-
-
84892461172
-
Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells
-
Church SE, Jensen SM, Antony PA, Restifo NP, Fox BA. Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells. Eur J Immunol. 2014;44(1):69-79.
-
(2014)
Eur J Immunol
, vol.44
, Issue.1
, pp. 69-79
-
-
Church, S.E.1
Jensen, S.M.2
Antony, P.A.3
Restifo, N.P.4
Fox, B.A.5
-
20
-
-
84885102010
-
Comparison of vaccineinduced effector CD8 T cell responses directed against self-and non-self-Tumor antigens: Implications for cancer immunotherapy
-
Pedersen SR, Sorensen MR, Buus S, Christensen JP, Thomsen AR. Comparison of vaccineinduced effector CD8 T cell responses directed against self-and non-self-Tumor antigens: implications for cancer immunotherapy. J Immunol. 2013;191(7):3955-3967.
-
(2013)
J Immunol
, vol.191
, Issue.7
, pp. 3955-3967
-
-
Pedersen, S.R.1
Sorensen, M.R.2
Buus, S.3
Christensen, J.P.4
Thomsen, A.R.5
-
21
-
-
77949895922
-
Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-Targeted immunotherapy in metastatic castration-resistant prostate cancer
-
Kantoff PW, et al. Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-Targeted immunotherapy in metastatic castration-resistant prostate cancer. J Clin Oncol. 2010;28(7):1099-1105.
-
(2011)
J Clin Oncol
, vol.28
, Issue.7
, pp. 1099-1105
-
-
Kantoff, P.W.1
-
22
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med. 2010;363(5):411-422.
-
(2011)
N Engl J Med
, vol.363
, Issue.5
, pp. 411-422
-
-
Kantoff, P.W.1
-
23
-
-
84936885250
-
Survivin and PSMA loaded dendritic cell vaccine for the treatment of prostate cancer
-
Xi HB, Wang GX, Fu B, Liu WP, Li Y. Survivin and PSMA loaded dendritic cell vaccine for the treatment of prostate cancer. Biol Pharm Bull. 2015;38(6):827-835.
-
(2015)
Biol Pharm Bull
, vol.38
, Issue.6
, pp. 827-835
-
-
Xi, H.B.1
Wang, G.X.2
Fu, B.3
Liu, W.P.4
Li, Y.5
-
24
-
-
84864472497
-
IGKV3 proteins as candidate "off-The-shelf " vaccines for κ-light chain-restricted B-cell non-Hodgkin lymphomas
-
Martorelli D, et al. IGKV3 proteins as candidate "off-The-shelf " vaccines for κ-light chain-restricted B-cell non-Hodgkin lymphomas. Clin Cancer Res. 2012;18(15):4080-4091.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.15
, pp. 4080-4091
-
-
Martorelli, D.1
-
25
-
-
73149115486
-
Aires partners in the molecular control of immunological tolerance
-
Abramson J, Giraud M, Benoist C, Mathis D. Aires partners in the molecular control of immunological tolerance. Cell. 2010;140(1):123-135.
-
(2011)
Cell
, vol.140
, Issue.1
, pp. 123-135
-
-
Abramson, J.1
Giraud, M.2
Benoist, C.3
Mathis, D.4
-
26
-
-
0036812718
-
Antigens derived from melanocyte differentiation proteins: Self-Tolerance, autoimmunity, and use for cancer immunotherapy
-
Engelhard VH, Bullock TN, Colella TA, Sheasley SL, Mullins DW. Antigens derived from melanocyte differentiation proteins: self-Tolerance, autoimmunity, and use for cancer immunotherapy. Immunol Rev. 2002;188:136-146.
-
(2002)
Immunol Rev
, vol.188
, pp. 136-146
-
-
Engelhard, V.H.1
Bullock, T.N.2
Colella, T.A.3
Sheasley, S.L.4
Mullins, D.W.5
-
27
-
-
72949104779
-
Antigen presentation in the thymus for positive selection and central tolerance induction
-
Klein L, Hinterberger M, Wirnsberger G, Kyewski B. Antigen presentation in the thymus for positive selection and central tolerance induction. Nat Rev Immunol. 2009;9(12):833-844.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.12
, pp. 833-844
-
-
Klein, L.1
Hinterberger, M.2
Wirnsberger, G.3
Kyewski, B.4
-
28
-
-
22244447452
-
Expression of a natural tumor antigen by thymic epithelial cells impairs the tumor-protective CD4+ T-cell repertoire
-
Bos R, et al. Expression of a natural tumor antigen by thymic epithelial cells impairs the tumor-protective CD4+ T-cell repertoire. Cancer Res. 2005;65(14):6443-6449.
-
(2005)
Cancer Res
, vol.65
, Issue.14
, pp. 6443-6449
-
-
Bos, R.1
-
29
-
-
84907830964
-
Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells
-
Pinto S, et al. Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells. Eur J Immunol. 2014;44(9):2811-2821.
-
(2014)
Eur J Immunol
, vol.44
, Issue.9
, pp. 2811-2821
-
-
Pinto, S.1
-
30
-
-
84919662329
-
Activated lymphocyte recruitment into the tumor microenvironment following preoperative sipuleucel-T for localized prostate cancer
-
dju268
-
Fong L, et al. Activated lymphocyte recruitment into the tumor microenvironment following preoperative sipuleucel-T for localized prostate cancer. J Natl Cancer Inst. 2014;106(11):dju268.
-
(2014)
J Natl Cancer Inst
, vol.106
, Issue.11
-
-
Fong, L.1
-
31
-
-
84940607297
-
A national multicenter phase 2 study of prostate-specific antigen (PSA) pox virus vaccine with sequential androgen ablation therapy in patients with PSA Progression: ECOG 9802
-
14. 01265-2
-
DiPaola RS, et al. A National Multicenter Phase 2 Study of Prostate-specific Antigen (PSA) Pox Virus Vaccine with Sequential Androgen Ablation Therapy in Patients with PSA Progression: ECOG 9802. Eur Urol. 2014;S0302-2838(14):01265-2.
-
(2014)
Eur Urol
, pp. S0302-2838
-
-
Dipaola, R.S.1
-
32
-
-
84996548609
-
Immune impact induced by PROSTVAC (PSA-TRICOM), a therapeutic vaccine for prostate cancer
-
Gulley JL, et al. Immune impact induced by PROSTVAC (PSA-TRICOM), a therapeutic vaccine for prostate cancer. Cancer Immunol Res. 2014;2(2):133-141.
-
(2014)
Cancer Immunol Res
, vol.2
, Issue.2
, pp. 133-141
-
-
Gulley, J.L.1
-
33
-
-
84864662070
-
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
-
Walter S, et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med. 2012;18(8):1254-1261.
-
(2012)
Nat Med
, vol.18
, Issue.8
, pp. 1254-1261
-
-
Walter, S.1
-
34
-
-
79957831345
-
Gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
-
Schwartzentruber DJ, et al. gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. N Engl J Med. 2011;364(22):2119-2127.
-
(2011)
N Engl J Med
, vol.364
, Issue.22
, pp. 2119-2127
-
-
Schwartzentruber, D.J.1
-
35
-
-
84929431322
-
Safety and survival with gvax pancreas prime and listeria monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer
-
Le DT, et al. Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes-Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer. J Clin Oncol. 2015;33(12):1325-1333.
-
(2015)
J Clin Oncol
, vol.33
, Issue.12
, pp. 1325-1333
-
-
Le, D.T.1
-
36
-
-
84879066269
-
An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma
-
Reardon DA, et al. An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma. Expert Rev Vaccines. 2013;12(6):597-615.
-
(2013)
Expert Rev Vaccines
, vol.12
, Issue.6
, pp. 597-615
-
-
Reardon, D.A.1
-
37
-
-
84893153864
-
Tumor lysate-loaded biodegradable microparticles as cancer vaccines
-
Joshi VB, Geary SM, Gross BP, Wongrakpanich A, Norian LA, Salem AK. Tumor lysate-loaded biodegradable microparticles as cancer vaccines. Expert Rev Vaccines. 2014;13(1):9-15.
-
(2014)
Expert Rev Vaccines
, vol.13
, Issue.1
, pp. 9-15
-
-
Joshi, V.B.1
Geary, S.M.2
Gross, B.P.3
Wongrakpanich, A.4
Norian, L.A.5
Salem, A.K.6
-
38
-
-
84861126779
-
Lymphoma vaccine therapy: Next steps after a positive, controlled phase III clinical trial
-
Thomas SK, Kwak LW. Lymphoma vaccine therapy: next steps after a positive, controlled phase III clinical trial. Semin Oncol. 2012;39(3):253-262.
-
(2012)
Semin Oncol
, vol.39
, Issue.3
, pp. 253-262
-
-
Thomas, S.K.1
Kwak, L.W.2
-
39
-
-
84878931351
-
Targeting T cells to tumor cells using bispecific antibodies
-
Frankel SR, Baeuerle PA. Targeting T cells to tumor cells using bispecific antibodies. Curr Opin Chem Biol. 2013;17(3):385-392.
-
(2013)
Curr Opin Chem Biol
, vol.17
, Issue.3
, pp. 385-392
-
-
Frankel, S.R.1
Baeuerle, P.A.2
-
40
-
-
78650653451
-
Wilms Tumor Protein 1" (WT1) peptide vaccination-induced complete remission in a patient with acute myeloid leukemia is accompanied by the emergence of a predominant T-cell clone both in blood and bone marrow
-
Ochsenreither S, et al. "Wilms Tumor Protein 1" (WT1) peptide vaccination-induced complete remission in a patient with acute myeloid leukemia is accompanied by the emergence of a predominant T-cell clone both in blood and bone marrow. J Immunother. 2011;34(1):85-91.
-
(2011)
J Immunother
, vol.34
, Issue.1
, pp. 85-91
-
-
Ochsenreither, S.1
-
41
-
-
84860798495
-
Wilms tumor protein 1 (WT1) peptide vaccination in AML patients: Predominant TCR CDR3beta sequence associated with remission in one patient is detectable in other vaccinated patients
-
Ochsenreither S, et al. Wilms tumor protein 1 (WT1) peptide vaccination in AML patients: predominant TCR CDR3beta sequence associated with remission in one patient is detectable in other vaccinated patients. Cancer Immunol Immunother. 2012;61(3):313-322.
-
(2012)
Cancer Immunol Immunother
, vol.61
, Issue.3
, pp. 313-322
-
-
Ochsenreither, S.1
-
42
-
-
77956384935
-
Induction of complete and molecular remissions in acute myeloid leukemia by Wilms tumor 1 antigen-Targeted dendritic cell vaccination
-
Van Tendeloo VF, et al. Induction of complete and molecular remissions in acute myeloid leukemia by Wilms tumor 1 antigen-Targeted dendritic cell vaccination. Proc Natl Acad Sci U S A. 2010;107(31):13824-13829.
-
(2011)
Proc Natl Acad Sci U S A
, vol.107
, Issue.31
, pp. 13824-13829
-
-
Van Tendeloo, V.F.1
-
43
-
-
84900869746
-
Paradigm shift in dendritic cell-based immunotherapy: From in vitro generated monocyte-derived DCs to naturally circulating DC subsets
-
Wimmers F, Schreibelt G, Skold AE, Figdor CG, de Vries IJ. Paradigm shift in dendritic cell-based immunotherapy: from in vitro generated monocyte-derived DCs to naturally circulating DC subsets. Front Immunol. 2014;5:165.
-
(2014)
Front Immunol
, vol.5
, pp. 165
-
-
Wimmers, F.1
Schreibelt, G.2
Skold, A.E.3
Figdor, C.G.4
De Vries, I.J.5
-
44
-
-
84871943629
-
Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination
-
Aarntzen EH, et al. Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination. Cancer Res. 2013;73(1):19-29.
-
(2013)
Cancer Res
, vol.73
, Issue.1
, pp. 19-29
-
-
Aarntzen, E.H.1
-
45
-
-
84907803841
-
Concurrent interaction of DCs with CD4(+) and CD8(+) T cells improves secondary CTL expansion: It takes three to tango
-
Hoyer S, et al. Concurrent interaction of DCs with CD4(+) and CD8(+) T cells improves secondary CTL expansion: It takes three to tango. Eur J Immunol. 2014;44(12):3543-3559.
-
(2014)
Eur J Immunol
, vol.44
, Issue.12
, pp. 3543-3559
-
-
Hoyer, S.1
-
46
-
-
84870312427
-
Skin-Test infiltrating lymphocytes early predict clinical outcome of dendritic cell-based vaccination in metastatic melanoma
-
Aarntzen EH, et al. Skin-Test infiltrating lymphocytes early predict clinical outcome of dendritic cell-based vaccination in metastatic melanoma. Cancer Res. 2012;72(23):6102-6110.
-
(2012)
Cancer Res
, vol.72
, Issue.23
, pp. 6102-6110
-
-
Aarntzen, E.H.1
-
47
-
-
84925493908
-
Long-Term clinical outcome of melanoma patients treated with messenger RNA-electroporated dendritic cell therapy following complete resection of metastases
-
Wilgenhof S, et al. Long-Term clinical outcome of melanoma patients treated with messenger RNA-electroporated dendritic cell therapy following complete resection of metastases. Cancer Immunol Immunother. 2015;64(3):381-388.
-
(2015)
Cancer Immunol Immunother
, vol.64
, Issue.3
, pp. 381-388
-
-
Wilgenhof, S.1
-
48
-
-
84883251918
-
Targeting the tumor mutanome for personalized vaccination therapy
-
Kreiter S, Castle JC, Tureci O, Sahin U. Targeting the tumor mutanome for personalized vaccination therapy. Oncoimmunology. 2012;1(5):768-769.
-
(2012)
Oncoimmunology
, vol.1
, Issue.5
, pp. 768-769
-
-
Kreiter, S.1
Castle, J.C.2
Tureci, O.3
Sahin, U.4
-
49
-
-
84857725402
-
Exploiting the mutanome for tumor vaccination
-
Castle JC, et al. Exploiting the mutanome for tumor vaccination. Cancer Res. 2012;72(5):1081-1091.
-
(2012)
Cancer Res
, vol.72
, Issue.5
, pp. 1081-1091
-
-
Castle, J.C.1
-
50
-
-
84920921528
-
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
-
Gubin MM, et al. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature. 2014;515(7528):577-581.
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 577-581
-
-
Gubin, M.M.1
-
51
-
-
84920956731
-
Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
-
Yadav M, et al. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature. 2014;515(7528):572-576.
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 572-576
-
-
Yadav, M.1
-
52
-
-
84918828514
-
Genetic basis for clinical response to CTLA-4 blockade in melanoma
-
Snyder A, et al. Genetic basis for clinical response to CTLA-4 blockade in melanoma. N Engl J Med. 2014;371(23):2189-2199.
-
(2014)
N Engl J Med
, vol.371
, Issue.23
, pp. 2189-2199
-
-
Snyder, A.1
-
53
-
-
84872841412
-
Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma
-
van Rooij N, et al. Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma. J Clin Oncol. 2013;31(32):e439-e442.
-
(2013)
J Clin Oncol
, vol.31
, Issue.32
, pp. e439-e442
-
-
Van Rooij, N.1
-
54
-
-
84907284200
-
Anti-CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response
-
254ra128
-
Kvistborg P, et al. Anti-CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response. Sci Transl Med. 2014;6(254):254ra128.
-
(2014)
Sci Transl Med
, vol.6
, Issue.254
-
-
Kvistborg, P.1
-
55
-
-
84900301377
-
Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer
-
Tran E, et al. Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer. Science. 2014;344(6184):641-645.
-
(2014)
Science
, vol.344
, Issue.6184
, pp. 641-645
-
-
Tran, E.1
-
56
-
-
84961323160
-
High-Throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
-
Linnemann C, et al. High-Throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma. Nat Med. 2015;21(1):81-85.
-
(2015)
Nat Med
, vol.21
, Issue.1
, pp. 81-85
-
-
Linnemann, C.1
-
57
-
-
84903846565
-
Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions
-
Lu YC, et al. Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions. Clin Cancer Res. 2014;20(13):3401-3410.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.13
, pp. 3401-3410
-
-
Lu, Y.C.1
-
58
-
-
84861648384
-
Global burden of cancers attributable to infections in 2008: A review and syn-Thetic analysis
-
de Martel C, et al. Global burden of cancers attributable to infections in 2008: a review and syn-Thetic analysis. Lancet Oncol. 2012;13(6):607-615.
-
(2012)
Lancet Oncol
, vol.13
, Issue.6
, pp. 607-615
-
-
De Martel, C.1
-
59
-
-
84921986200
-
Pathogen-driven cancers and emerging immune therapeutic strategies
-
Vandeven N, Nghiem P. Pathogen-driven cancers and emerging immune therapeutic strategies. Cancer Immunol Res. 2014;2(1):9-14.
-
(2014)
Cancer Immunol Res
, vol.2
, Issue.1
, pp. 9-14
-
-
Vandeven, N.1
Nghiem, P.2
-
60
-
-
84911921975
-
The global burden of liver disease: The major impact of China
-
Wang FS, Fan JG, Zhang Z, Gao B, Wang HY. The global burden of liver disease: the major impact of China. Hepatology. 2014;60(6):2099-2108.
-
(2014)
Hepatology
, vol.60
, Issue.6
, pp. 2099-2108
-
-
Wang, F.S.1
Fan, J.G.2
Zhang, Z.3
Gao, B.4
Wang, H.Y.5
-
61
-
-
84905258651
-
Strategies to eliminate HBV infection
-
Kapoor R, Kottilil S. Strategies to eliminate HBV infection. Future Virol. 2014;9(6):565-585.
-
(2014)
Future Virol
, vol.9
, Issue.6
, pp. 565-585
-
-
Kapoor, R.1
Kottilil, S.2
-
62
-
-
50149120755
-
A randomized controlled phase IIb trial of antigen-antibody immunogenic complex therapeutic vaccine in chronic hepatitis B patients
-
Xu DZ, et al. A randomized controlled phase IIb trial of antigen-antibody immunogenic complex therapeutic vaccine in chronic hepatitis B patients. PLoS One. 2008;3(7):e2565.
-
(2008)
PLoS One
, vol.3
, Issue.7
, pp. e2565
-
-
Xu, D.Z.1
-
63
-
-
84882811237
-
Results of a phase III clinical trial with an HBsAg-HBIG immunogenic complex therapeutic vaccine for chronic hepatitis B patients: Experiences and findings
-
Xu DZ, et al. Results of a phase III clinical trial with an HBsAg-HBIG immunogenic complex therapeutic vaccine for chronic hepatitis B patients: experiences and findings. J Hepatol. 2013;59(3):450-456.
-
(2013)
J Hepatol
, vol.59
, Issue.3
, pp. 450-456
-
-
Xu, D.Z.1
-
64
-
-
84896739014
-
Therapeutic vaccines against hepatitis C virus
-
Xue J, Zhu H, Chen Z. Therapeutic vaccines against hepatitis C virus. Infect Genet Evol. 2014;22:120-129.
-
(2014)
Infect Genet Evol
, vol.22
, pp. 120-129
-
-
Xue, J.1
Zhu, H.2
Chen, Z.3
-
65
-
-
0348230938
-
Dual stimulation of Epstein-Barr Virus (EBV)-specific CD4+-and CD8+-T-cell responses by a chimeric antigen construct: Potential therapeutic vaccine for EBV-positive nasopharyngeal carcinoma
-
Taylor GS, et al. Dual stimulation of Epstein-Barr Virus (EBV)-specific CD4+-and CD8+-T-cell responses by a chimeric antigen construct: potential therapeutic vaccine for EBV-positive nasopharyngeal carcinoma. J Virol. 2004;78(2):768-778.
-
(2004)
J Virol
, vol.78
, Issue.2
, pp. 768-778
-
-
Taylor, G.S.1
-
66
-
-
84875451942
-
Phase i trial of recombinant modified vaccinia ankara encoding Epstein-Barr viral tumor antigens in nasopharyngeal carcinoma patients
-
Hui EP, et al. Phase I trial of recombinant modified vaccinia ankara encoding Epstein-Barr viral tumor antigens in nasopharyngeal carcinoma patients. Cancer Res. 2013;73(6):1676-1688.
-
(2013)
Cancer Res
, vol.73
, Issue.6
, pp. 1676-1688
-
-
Hui, E.P.1
-
67
-
-
84908517914
-
A recombinant modified vaccinia ankara vaccine encoding Epstein-Barr Virus (EBV) target antigens: A phase i trial in UK patients with EBV-positive cancer
-
Taylor GS, et al. A recombinant modified vaccinia ankara vaccine encoding Epstein-Barr Virus (EBV) target antigens: a phase I trial in UK patients with EBV-positive cancer. Clin Cancer Res. 2014;20(19):5009-5022.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.19
, pp. 5009-5022
-
-
Taylor, G.S.1
-
68
-
-
84876696649
-
The need and challenges for development of an Epstein-Barr virus vaccine
-
Cohen JI, Mocarski ES, Raab-Traub N, Corey L, Nabel GJ. The need and challenges for development of an Epstein-Barr virus vaccine. Vaccine. 2013;31(suppl 2):B194-B196.
-
(2013)
Vaccine
, vol.31
, pp. B194-B196
-
-
Cohen, J.I.1
Mocarski, E.S.2
Raab-Traub, N.3
Corey, L.4
Nabel, G.J.5
-
69
-
-
84927694937
-
Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study
-
Suehiro Y, et al. Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study. Br J Haematol. 2015;169(3):356-367.
-
(2015)
Br J Haematol
, vol.169
, Issue.3
, pp. 356-367
-
-
Suehiro, Y.1
-
70
-
-
39749113080
-
Clonal integration of a polyomavirus in human Merkel cell carcinoma
-
Feng H, Shuda M, Chang Y, Moore PS. Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science. 2008;319(5866):1096-1100.
-
(2008)
Science
, vol.319
, Issue.5866
, pp. 1096-1100
-
-
Feng, H.1
Shuda, M.2
Chang, Y.3
Moore, P.S.4
-
71
-
-
84870662318
-
Merkel cell polyomavirus: A newly discovered human virus with oncogenic potential
-
Spurgeon ME, Lambert PF. Merkel cell polyomavirus: a newly discovered human virus with oncogenic potential. Virology. 2013;435(1):118-130.
-
(2013)
Virology
, vol.435
, Issue.1
, pp. 118-130
-
-
Spurgeon, M.E.1
Lambert, P.F.2
-
72
-
-
84910620489
-
Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I
-
Chapuis AG, et al. Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I. Cancer Immunol Res. 2014;2(1):27-36.
-
(2014)
Cancer Immunol Res
, vol.2
, Issue.1
, pp. 27-36
-
-
Chapuis, A.G.1
-
73
-
-
84880121159
-
Creation of a Merkel cell polyomavirus small T antigen-expressing murine tumor model and a DNA vaccine targeting small T antigen
-
Gomez B, He L, Tsai YC, Wu TC, Viscidi RP, Hung CF. Creation of a Merkel cell polyomavirus small T antigen-expressing murine tumor model and a DNA vaccine targeting small T antigen. Cell Biosci. 2013;3(1):29.
-
(2013)
Cell Biosci
, vol.3
, Issue.1
, pp. 29
-
-
Gomez, B.1
He, L.2
Tsai, Y.C.3
Wu, T.C.4
Viscidi, R.P.5
Hung, C.F.6
-
74
-
-
84887601556
-
Comprehensive control of human papillomavirus infections and related diseases
-
Bosch FX, et al. Comprehensive control of human papillomavirus infections and related diseases. Vaccine. 2013;31(suppl 8):I1-I31.
-
(2013)
Vaccine
, vol.31
, pp. I1-I31
-
-
Bosch, F.X.1
-
75
-
-
84881028424
-
Epidemiology of oralcavity and oropharyngeal carcinomas: Controlling a tobacco epidemic while a human papillomavirus epidemic emerges
-
Hashibe M, Sturgis EM. Epidemiology of oralcavity and oropharyngeal carcinomas: controlling a tobacco epidemic while a human papillomavirus epidemic emerges. Otolaryngol Clin North Am. 2013;46(4):507-520.
-
(2013)
Otolaryngol Clin North Am
, vol.46
, Issue.4
, pp. 507-520
-
-
Hashibe, M.1
Sturgis, E.M.2
-
76
-
-
84892750822
-
Barriers to human papillomavirus vaccination among US adolescents: A systematic review of the literature
-
Holman DM, Benard V, Roland KB, Watson M, Liddon N, Stokley S. Barriers to human papillomavirus vaccination among US adolescents: a systematic review of the literature. JAMA Pediatr. 2014;168(1):76-82.
-
(2014)
JAMA Pediatr
, vol.168
, Issue.1
, pp. 76-82
-
-
Holman, D.M.1
Benard, V.2
Roland, K.B.3
Watson, M.4
Liddon, N.5
Stokley, S.6
-
77
-
-
84882284393
-
Prospects of combinatorial synthetic peptide vaccine-based immunotherapy against cancer
-
Arens R, van Hall T, van der Burg SH, Ossendorp F, Melief CJ. Prospects of combinatorial synthetic peptide vaccine-based immunotherapy against cancer. Semin Immunol. 2013;25(2):182-190.
-
(2013)
Semin Immunol
, vol.25
, Issue.2
, pp. 182-190
-
-
Arens, R.1
Van Hall, T.2
Van Der Burg, S.H.3
Ossendorp, F.4
Melief, C.J.5
-
78
-
-
84858776559
-
Experience with synthetic vaccines for cancer and persistent virus infections in nonhuman primates and patients
-
Quakkelaar ED, Melief CJ. Experience with synthetic vaccines for cancer and persistent virus infections in nonhuman primates and patients. Adv Immunol. 2012;114:77-106.
-
(2012)
Adv Immunol
, vol.114
, pp. 77-106
-
-
Quakkelaar, E.D.1
Melief, C.J.2
-
79
-
-
84858776331
-
Mechanisms of peptide vaccination in mouse models: Tolerance, immunity, and hyperreactivity
-
van Hall T, van der Burg SH. Mechanisms of peptide vaccination in mouse models: tolerance, immunity, and hyperreactivity. Adv Immunol. 2012;114:51-76.
-
(2012)
Adv Immunol
, vol.114
, pp. 51-76
-
-
Van Hall, T.1
Van Der Burg, S.H.2
-
80
-
-
42549138499
-
Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines
-
Melief CJ, van der Burg SH. Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines. Nat Rev Cancer. 2008;8(5):351-360.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.5
, pp. 351-360
-
-
Melief, C.J.1
Van Der Burg, S.H.2
-
81
-
-
79953113656
-
Therapeutic vaccination against human papilloma virus induced malignancies
-
van der Burg SH, Melief CJ. Therapeutic vaccination against human papilloma virus induced malignancies. Curr Opin Immunol. 2011;23(2):252-257.
-
(2011)
Curr Opin Immunol
, vol.23
, Issue.2
, pp. 252-257
-
-
Van Der Burg, S.H.1
Melief, C.J.2
-
82
-
-
84902261184
-
Immunologic treatments for precancerous lesions and uterine cervical cancer
-
Vici P, et al. Immunologic treatments for precancerous lesions and uterine cervical cancer. J Exp Clin Cancer Res. 2014;33(1):29.
-
(2014)
J Exp Clin Cancer Res
, vol.33
, Issue.1
, pp. 29
-
-
Vici, P.1
-
83
-
-
70350772293
-
Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia
-
Kenter GG, et al. Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. N Engl J Med. 2009;361(19):1838-1847.
-
(2009)
N Engl J Med
, vol.361
, Issue.19
, pp. 1838-1847
-
-
Kenter, G.G.1
-
84
-
-
77955411096
-
Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses
-
Welters MJ, et al. Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses. Proc Natl Acad Sci U S A. 2010;107(26):11895-11899.
-
(2011)
Proc Natl Acad Sci U S A
, vol.107
, Issue.26
, pp. 11895-11899
-
-
Welters, M.J.1
-
85
-
-
84875689800
-
HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial
-
van Poelgeest MI, et al. HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial. J Transl Med. 2013;11:88.
-
(2013)
J Transl Med
, vol.11
, pp. 88
-
-
Van Poelgeest, M.I.1
-
86
-
-
77950370339
-
Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia
-
Daayana S, et al. Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia. Br J Cancer. 2010;102(7):1129-1136.
-
(2011)
Br J Cancer
, vol.102
, Issue.7
, pp. 1129-1136
-
-
Daayana, S.1
-
87
-
-
84867437406
-
Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses
-
Bagarazzi ML, et al. Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses. Sci Transl Med. 2012;4(155):155ra138.
-
(2012)
Sci Transl Med
, vol.4
, Issue.155
, pp. 155ra138
-
-
Bagarazzi, M.L.1
-
88
-
-
84921357729
-
Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients
-
Kim TJ, et al. Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients. Nat Commun. 2014;5:5317.
-
(2014)
Nat Commun
, vol.5
, pp. 5317
-
-
Kim, T.J.1
-
89
-
-
84921710069
-
ADXS-HPV: A therapeutic Listeria vaccination targeting cervical cancers expressing the HPV E7 antigen
-
Cory L, Chu C. ADXS-HPV: a therapeutic Listeria vaccination targeting cervical cancers expressing the HPV E7 antigen. Hum Vaccin Immunother. 2014;10(11):3190-3195.
-
(2014)
Hum Vaccin Immunother
, vol.10
, Issue.11
, pp. 3190-3195
-
-
Cory, L.1
Chu, C.2
-
90
-
-
84915805617
-
Human cytomegalovirus antigens in malignant gliomas as targets for adoptive cellular therapy
-
Landi D, Hegde M, Ahmed N. Human cytomegalovirus antigens in malignant gliomas as targets for adoptive cellular therapy. Front Oncol. 2014;4:338.
-
(2014)
Front Oncol
, vol.4
, pp. 338
-
-
Landi, D.1
Hegde, M.2
Ahmed, N.3
-
91
-
-
84925045090
-
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
-
Mitchell DA, et al. Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients. Nature. 2015;519(7543):366-369.
-
(2015)
Nature
, vol.519
, Issue.7543
, pp. 366-369
-
-
Mitchell, D.A.1
-
92
-
-
84907541219
-
Immune control and failure in HCV infection -Tipping the balance
-
Dustin LB, Cashman SB, Laidlaw SM. Immune control and failure in HCV infection -Tipping the balance. J Leukoc Biol. 2014;96(4):535-548.
-
(2014)
J Leukoc Biol
, vol.96
, Issue.4
, pp. 535-548
-
-
Dustin, L.B.1
Cashman, S.B.2
Laidlaw, S.M.3
-
93
-
-
85056058886
-
The invisible enemy -how human papillomaviruses avoid recognition and clearance by the host immune system
-
Grabowska AK, Riemer AB. The invisible enemy -how human papillomaviruses avoid recognition and clearance by the host immune system. Open Virol J. 2012;6:249-256.
-
(2012)
Open Virol J
, vol.6
, pp. 249-256
-
-
Grabowska, A.K.1
Riemer, A.B.2
-
94
-
-
84926197178
-
Immune escape of γ-herpesviruses from adaptive immunity
-
Hu Z, Usherwood EJ. Immune escape of γ-herpesviruses from adaptive immunity. Rev Med Virol. 2014;24(6):365-378.
-
(2014)
Rev Med Virol
, vol.24
, Issue.6
, pp. 365-378
-
-
Hu, Z.1
Usherwood, E.J.2
-
95
-
-
78650182082
-
Immunopathogenesis of lymphoma: Focus on CCR4
-
Ishida T, Ueda R. Immunopathogenesis of lymphoma: focus on CCR4. Cancer Sci. 2011;102(1):44-50.
-
(2011)
Cancer Sci
, vol.102
, Issue.1
, pp. 44-50
-
-
Ishida, T.1
Ueda, R.2
-
96
-
-
84878509069
-
Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocytes innate immune response
-
Karim R, et al. Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocytes innate immune response. PLoS Pathog. 2013;9(5):e1003384.
-
(2013)
PLoS Pathog
, vol.9
, Issue.5
, pp. e1003384
-
-
Karim, R.1
-
97
-
-
84927783847
-
Human hepatitis B virus S and e antigens inhibit major vault protein signaling in interferon induction pathways
-
Liu S, et al. Human hepatitis B virus S and E antigens inhibit major vault protein signaling in interferon induction pathways. J Hepatol. 2015;62(5):1015-1023.
-
(2015)
J Hepatol
, vol.62
, Issue.5
, pp. 1015-1023
-
-
Liu, S.1
-
98
-
-
84921638462
-
Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways
-
Liu Y, et al. Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways. J Virol. 2015;89(4):2287-2300.
-
(2015)
J Virol
, vol.89
, Issue.4
, pp. 2287-2300
-
-
Liu, Y.1
-
99
-
-
84893965118
-
Immune modulation in cancer with antibodies
-
Page DB, Postow MA, Callahan MK, Allison JP, Wolchok JD. Immune modulation in cancer with antibodies. Annu Rev Med. 2014;65:185-202.
-
(2014)
Annu Rev Med
, vol.65
, pp. 185-202
-
-
Page, D.B.1
Postow, M.A.2
Callahan, M.K.3
Allison, J.P.4
Wolchok, J.D.5
-
100
-
-
0035903324
-
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
-
Sutmuller RP, et al. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med. 2001;194(6):823-832.
-
(2001)
J Exp Med
, vol.194
, Issue.6
, pp. 823-832
-
-
Sutmuller, R.P.1
-
101
-
-
0033517152
-
Combination immunotherapy of B16 melanoma using anticytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colonystimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
-
van Elsas A, Hurwitz AA, Allison JP. Combination immunotherapy of B16 melanoma using anticytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colonystimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med. 1999;190(3):355-366.
-
(1999)
J Exp Med
, vol.190
, Issue.3
, pp. 355-366
-
-
Van Elsas, A.1
Hurwitz, A.A.2
Allison, J.P.3
-
102
-
-
84892448554
-
Regulatory T cells in cancer immunotherapy
-
Nishikawa H, Sakaguchi S. Regulatory T cells in cancer immunotherapy. Curr Opin Immunol. 2014;27:1-7.
-
(2014)
Curr Opin Immunol
, vol.27
, pp. 1-7
-
-
Nishikawa, H.1
Sakaguchi, S.2
-
104
-
-
84923692138
-
Complexity and challenges in defining myeloid-derived suppressor cells
-
[Published online ahead of print November 26, 2014]
-
Damuzzo V, et al. Complexity and challenges in defining myeloid-derived suppressor cells [published online ahead of print November 26, 2014]. Cytometry B Clin Cytom. doi:10.1002/cytob.21206.
-
Cytometry B Clin Cytom
-
-
Damuzzo, V.1
-
105
-
-
84904338340
-
Tumour-induced immune suppression: Role of inflammatory mediators released by myelomonocytic cells
-
Mao Y, Poschke I, Kiessling R. Tumour-induced immune suppression: role of inflammatory mediators released by myelomonocytic cells. J Intern Med. 2014;276(2):154-170.
-
(2014)
J Intern Med
, vol.276
, Issue.2
, pp. 154-170
-
-
Mao, Y.1
Poschke, I.2
Kiessling, R.3
-
106
-
-
84885457151
-
TGF-β: Guardian of T cell function
-
Oh SA, Li MO. TGF-β: guardian of T cell function. J Immunol. 2013;191(8):3973-3979.
-
(2013)
J Immunol
, vol.191
, Issue.8
, pp. 3973-3979
-
-
Oh, S.A.1
Li, M.O.2
-
107
-
-
84885433913
-
Current status of interleukin-10 and regulatory T-cells in cancer
-
Dennis KL, Blatner NR, Gounari F, Khazaie K. Current status of interleukin-10 and regulatory T-cells in cancer. Curr Opin Oncol. 2013;25(6):637-645.
-
(2013)
Curr Opin Oncol
, vol.25
, Issue.6
, pp. 637-645
-
-
Dennis, K.L.1
Blatner, N.R.2
Gounari, F.3
Khazaie, K.4
-
108
-
-
84877004454
-
Cytokine patterns in patients with cancer: A systematic review
-
Lippitz BE. Cytokine patterns in patients with cancer: a systematic review. Lancet Oncol. 2013;14(6):e218-e228.
-
(2013)
Lancet Oncol
, vol.14
, Issue.6
, pp. e218-e228
-
-
Lippitz, B.E.1
-
109
-
-
84921291171
-
Suppression of antigen presentation by IL-10
-
Mittal SK, Roche PA. Suppression of antigen presentation by IL-10. Curr Opin Immunol. 2015;34:22-27.
-
(2015)
Curr Opin Immunol
, vol.34
, pp. 22-27
-
-
Mittal, S.K.1
Roche, P.A.2
-
110
-
-
84918831332
-
Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA
-
Lemos H, Huang L, McGaha TL, Mellor AL. Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA. Eur J Immunol. 2014;44(10):2847-2853.
-
(2014)
Eur J Immunol
, vol.44
, Issue.10
, pp. 2847-2853
-
-
Lemos, H.1
Huang, L.2
McGaha, T.L.3
Mellor, A.L.4
-
111
-
-
84875261622
-
Indoleamine 2, 3 dioxygenase and metabolic control of immune responses
-
Munn DH, Mellor AL. Indoleamine 2, 3 dioxygenase and metabolic control of immune responses. Trends Immunol. 2013;34(3):137-143.
-
(2013)
Trends Immunol
, vol.34
, Issue.3
, pp. 137-143
-
-
Munn, D.H.1
Mellor, A.L.2
-
112
-
-
85015356291
-
Cancer immunotherapy by targeting IDO1/TDO and their downstream effectors
-
Platten M, von Knebel DN, Oezen I, Wick W, Ochs K. Cancer immunotherapy by targeting IDO1/TDO and their downstream effectors. Front Immunol. 2014;5:673.
-
(2014)
Front Immunol
, vol.5
, pp. 673
-
-
Platten, M.1
Von Knebel, D.N.2
Oezen, I.3
Wick, W.4
Ochs, K.5
-
114
-
-
84886698315
-
Innate and adaptive immune cells in the tumor microenvironment
-
Gajewski TF, Schreiber H, Fu YX. Innate and adaptive immune cells in the tumor microenvironment. Nat Immunol. 2013;14(10):1014-1022.
-
(2013)
Nat Immunol
, vol.14
, Issue.10
, pp. 1014-1022
-
-
Gajewski, T.F.1
Schreiber, H.2
Fu, Y.X.3
-
115
-
-
84897513740
-
Regulation of chemokine expression in the tumor microenvironment
-
Gorbachev AV, Fairchild RL. Regulation of chemokine expression in the tumor microenvironment. Crit Rev Immunol. 2014;34(2):103-120.
-
(2014)
Crit Rev Immunol
, vol.34
, Issue.2
, pp. 103-120
-
-
Gorbachev, A.V.1
Fairchild, R.L.2
-
116
-
-
84923311842
-
Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration
-
Zumwalt TJ, Arnold M, Goel A, Boland CR. Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration. Oncotarget. 2015;6(5):2981-2991.
-
(2015)
Oncotarget
, vol.6
, Issue.5
, pp. 2981-2991
-
-
Zumwalt, T.J.1
Arnold, M.2
Goel, A.3
Boland, C.R.4
-
117
-
-
84963952313
-
Versatile functions for IL-6 in metabolism and cancer
-
Mauer J, Denson JL, Bruning JC. Versatile functions for IL-6 in metabolism and cancer. Trends Immunol. 2015;36(2):92-101.
-
(2015)
Trends Immunol
, vol.36
, Issue.2
, pp. 92-101
-
-
Mauer, J.1
Denson, J.L.2
Bruning, J.C.3
-
118
-
-
84896494013
-
IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
-
Taniguchi K, Karin M. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer. Semin Immunol. 2014;26(1):54-74.
-
(2014)
Semin Immunol
, vol.26
, Issue.1
, pp. 54-74
-
-
Taniguchi, K.1
Karin, M.2
-
119
-
-
84908161000
-
Revisiting STAT3 signalling in cancer: New and unexpected biological functions
-
Yu H, Lee H, Herrmann A, Buettner R, Jove R. Revisiting STAT3 signalling in cancer: new and unexpected biological functions. Nat Rev Cancer. 2014;14(11):736-746.
-
(2014)
Nat Rev Cancer
, vol.14
, Issue.11
, pp. 736-746
-
-
Yu, H.1
Lee, H.2
Herrmann, A.3
Buettner, R.4
Jove, R.5
-
120
-
-
0032482356
-
Help for cytotoxic-Tcell responses is mediated by CD40 signalling
-
Bennett SR, Carbone FR, Karamalis F, Flavell RA, Miller JF, Heath WR. Help for cytotoxic-Tcell responses is mediated by CD40 signalling. Nature. 1998;393(6684):478-480.
-
(1998)
Nature
, vol.393
, Issue.6684
, pp. 478-480
-
-
Bennett, S.R.1
Carbone, F.R.2
Karamalis, F.3
Flavell, R.A.4
Miller, J.F.5
Heath, W.R.6
-
121
-
-
0022456451
-
Cooperation between cytotoxic and helper T lymphocytes in protection against lethal Sendai virus infection. Protection by T cells is MHC-restricted and MHC-regulated; A model for MHC-disease associations
-
Kast WM, Bronkhorst AM, de Waal LP, Melief CJ. Cooperation between cytotoxic and helper T lymphocytes in protection against lethal Sendai virus infection. Protection by T cells is MHC-restricted and MHC-regulated; a model for MHC-disease associations. J Exp Med. 1986;164(3):723-738.
-
(1986)
J Exp Med
, vol.164
, Issue.3
, pp. 723-738
-
-
Kast, W.M.1
Bronkhorst, A.M.2
De Waal, L.P.3
Melief, C.J.4
-
122
-
-
0032473562
-
Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors
-
Ossendorp F, Mengede E, Camps M, Filius R, Melief CJ. Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors. J Exp Med. 1998;187(5):693-702.
-
(1998)
J Exp Med
, vol.187
, Issue.5
, pp. 693-702
-
-
Ossendorp, F.1
Mengede, E.2
Camps, M.3
Filius, R.4
Melief, C.J.5
-
123
-
-
0032482337
-
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
-
Ridge JP, Di RF, Matzinger P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature. 1998;393(6684):474-478.
-
(1998)
Nature
, vol.393
, Issue.6684
, pp. 474-478
-
-
Ridge, J.P.1
Di Matzinger, R.F.P.2
-
124
-
-
0032482474
-
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
-
Schoenberger SP, Toes RE, van der Voort EI, Offringa R, Melief CJ. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature. 1998;393(6684):480-483.
-
(1998)
Nature
, vol.393
, Issue.6684
, pp. 480-483
-
-
Schoenberger, S.P.1
Toes, R.E.2
Van Der Voort, E.I.3
Offringa, R.4
Melief, C.J.5
-
125
-
-
0037456367
-
CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
-
Janssen EM, Lemmens EE, Wolfe T, Christen U, von Herrath MG, Schoenberger SP. CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature. 2003;421(6925):852-856.
-
(2003)
Nature
, vol.421
, Issue.6925
, pp. 852-856
-
-
Janssen, E.M.1
Lemmens, E.E.2
Wolfe, T.3
Christen, U.4
Von Herrath, M.G.5
Schoenberger, S.P.6
-
126
-
-
14544288632
-
CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death
-
Janssen EM, et al. CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature. 2005;434(7029):88-93.
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 88-93
-
-
Janssen, E.M.1
-
127
-
-
77949522803
-
Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
-
Quezada SA, et al. Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J Exp Med. 2010;207(3):637-650.
-
(2011)
J Exp Med
, vol.207
, Issue.3
, pp. 637-650
-
-
Quezada, S.A.1
-
128
-
-
38449106129
-
CD8+ CTL priming by exact peptide epitopes in incomplete Freunds adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity
-
Bijker MS, van den Eeden SJ, Franken KL, Melief CJ, Offringa R, van der Burg SH. CD8+ CTL priming by exact peptide epitopes in incomplete Freunds adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity. J Immunol. 2007;179(8):5033-5040.
-
(2007)
J Immunol
, vol.179
, Issue.8
, pp. 5033-5040
-
-
Bijker, M.S.1
Van Den Eeden, S.J.2
Franken, K.L.3
Melief, C.J.4
Offringa, R.5
Van Der Burg, S.H.6
-
129
-
-
0029798058
-
Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction
-
Toes RE, Offringa R, Blom RJ, Melief CJ, Kast WM. Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction. Proc Natl Acad Sci U S A. 1996;93(15):7855-7860.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.15
, pp. 7855-7860
-
-
Toes, R.E.1
Offringa, R.2
Blom, R.J.3
Melief, C.J.4
Kast, W.M.5
-
130
-
-
0029935569
-
Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors
-
Toes RE, Blom RJ, Offringa R, Kast WM, Melief CJ. Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors. J Immunol. 1996;156(10):3911-3918.
-
(1996)
J Immunol
, vol.156
, Issue.10
, pp. 3911-3918
-
-
Toes, R.E.1
Blom, R.J.2
Offringa, R.3
Kast, W.M.4
Melief, C.J.5
-
131
-
-
84878469107
-
Persistent antigen at vaccination sites induces tumor-specific CD8(+) T cell sequestration, dysfunction and deletion
-
Hailemichael Y, et al. Persistent antigen at vaccination sites induces tumor-specific CD8(+) T cell sequestration, dysfunction and deletion. Nat Med. 2013;19(4):465-472.
-
(2013)
Nat Med
, vol.19
, Issue.4
, pp. 465-472
-
-
Hailemichael, Y.1
-
132
-
-
0036644556
-
Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides
-
Zwaveling S, et al. Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J Immunol. 2002;169(1):350-358.
-
(2002)
J Immunol
, vol.169
, Issue.1
, pp. 350-358
-
-
Zwaveling, S.1
-
133
-
-
84870359509
-
Phase i trial of overlapping long peptides from a tumor self-antigen and poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients
-
Sabbatini P, et al. Phase I trial of overlapping long peptides from a tumor self-antigen and poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients. Clin Cancer Res. 2012;18(23):6497-6508.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.23
, pp. 6497-6508
-
-
Sabbatini, P.1
-
134
-
-
84921305177
-
Effect of Montanide and poly-ICLC adjuvant on human self/tumor antigen-specific CD4+ T cells in phase i overlapping long peptide vaccine trial
-
Tsuji T, et al. Effect of Montanide and poly-ICLC adjuvant on human self/tumor antigen-specific CD4+ T cells in phase I overlapping long peptide vaccine trial. Cancer Immunol Res. 2013;1(5):340-350.
-
(2013)
Cancer Immunol Res
, vol.1
, Issue.5
, pp. 340-350
-
-
Tsuji, T.1
-
135
-
-
84866551579
-
Vaccine-induced effector-memory CD8+ T cell responses predict therapeutic efficacy against tumors
-
van Duikeren S, et al. Vaccine-induced effector-memory CD8+ T cell responses predict therapeutic efficacy against tumors. J Immunol. 2012;189(7):3397-3403.
-
(2012)
J Immunol
, vol.189
, Issue.7
, pp. 3397-3403
-
-
Van Duikeren, S.1
-
136
-
-
0032080385
-
Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells
-
Toes RE, et al. Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells. J Immunol. 1998;160(9):4449-4456.
-
(1998)
J Immunol
, vol.160
, Issue.9
, pp. 4449-4456
-
-
Toes, R.E.1
-
137
-
-
84877825063
-
BiVax: A peptide/poly-IC subunit vaccine that mimics an acute infection elicits vast and effective anti-Tumor CD8 T-cell responses
-
Cho HI, Barrios K, Lee YR, Linowski AK, Celis E. BiVax: a peptide/poly-IC subunit vaccine that mimics an acute infection elicits vast and effective anti-Tumor CD8 T-cell responses. Cancer Immunol Immunother. 2013;62(4):787-799.
-
(2013)
Cancer Immunol Immunother
, vol.62
, Issue.4
, pp. 787-799
-
-
Cho, H.I.1
Barrios, K.2
Lee, Y.R.3
Linowski, A.K.4
Celis, E.5
-
138
-
-
0032984496
-
CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-Tumor vaccine efficacy
-
Diehl L, et al. CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-Tumor vaccine efficacy. Nat Med. 1999;5(7):774-779.
-
(1999)
Nat Med
, vol.5
, Issue.7
, pp. 774-779
-
-
Diehl, L.1
-
139
-
-
14644390867
-
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
-
Speiser DE, et al. Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J Clin Invest. 2005;115(3):739-746.
-
(2005)
J Clin Invest
, vol.115
, Issue.3
, pp. 739-746
-
-
Speiser, D.E.1
-
140
-
-
44849109375
-
Superior induction of anti-Tumor CTL immunity by extended peptide vaccines involves prolonged, DCfocused antigen presentation
-
Bijker MS, van den Eeden SJ, Franken KL, Melief CJ, van der Burg SH, Offringa R. Superior induction of anti-Tumor CTL immunity by extended peptide vaccines involves prolonged, DCfocused antigen presentation. Eur J Immunol. 2008;38(4):1033-1042.
-
(2008)
Eur J Immunol
, vol.38
, Issue.4
, pp. 1033-1042
-
-
Bijker, M.S.1
Van Den Eeden, S.J.2
Franken, K.L.3
Melief, C.J.4
Van Der Burg, S.H.5
Offringa, R.6
-
141
-
-
84885723472
-
Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation
-
Rosalia RA, et al. Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation. Eur J Immunol. 2013;43(10):2554-2565.
-
(2013)
Eur J Immunol
, vol.43
, Issue.10
, pp. 2554-2565
-
-
Rosalia, R.A.1
-
142
-
-
66149119372
-
Comparing pooled peptides with intact protein for accessing cross-presentation pathways for protective CD8+ and CD4+ T cells
-
Zhang H, et al. Comparing pooled peptides with intact protein for accessing cross-presentation pathways for protective CD8+ and CD4+ T cells. J Biol Chem. 2009;284(14):9184-9191.
-
(2009)
J Biol Chem
, vol.284
, Issue.14
, pp. 9184-9191
-
-
Zhang, H.1
-
143
-
-
84877945468
-
Immune system targeting by biodegradable nanoparticles for cancer vaccines
-
Silva JM, Videira M, Gaspar R, Preat V, Florindo HF. Immune system targeting by biodegradable nanoparticles for cancer vaccines. J Control Release. 2013;168(2):179-199.
-
(2013)
J Control Release
, vol.168
, Issue.2
, pp. 179-199
-
-
Silva, J.M.1
Videira, M.2
Gaspar, R.3
Preat, V.4
Florindo, H.F.5
-
144
-
-
84875493408
-
Memory T cell subsets, migration patterns, and tissue residence
-
Mueller SN, Gebhardt T, Carbone FR, Heath WR. Memory T cell subsets, migration patterns, and tissue residence. Annu Rev Immunol. 2013;31:137-161.
-
(2013)
Annu Rev Immunol
, vol.31
, pp. 137-161
-
-
Mueller, S.N.1
Gebhardt, T.2
Carbone, F.R.3
Heath, W.R.4
-
145
-
-
84895818551
-
Immune adjuvants as critical guides directing immunity triggered by therapeutic cancer vaccines
-
Schijns V, Tartour E, Michalek J, Stathopoulos A, Dobrovolskiene NT, Strioga MM. Immune adjuvants as critical guides directing immunity triggered by therapeutic cancer vaccines. Cytotherapy. 2014;16(4):427-439.
-
(2014)
Cytotherapy
, vol.16
, Issue.4
, pp. 427-439
-
-
Schijns, V.1
Tartour, E.2
Michalek, J.3
Stathopoulos, A.4
Dobrovolskiene, N.T.5
Strioga, M.M.6
-
146
-
-
33846090134
-
Multiple CD4 and CD8 T-cell activation parameters predict vaccine efficacy in vivo mediated by individual DC-activating agonists
-
Welters MJ, et al. Multiple CD4 and CD8 T-cell activation parameters predict vaccine efficacy in vivo mediated by individual DC-activating agonists. Vaccine. 2007;25(8):1379-1389.
-
(2007)
Vaccine
, vol.25
, Issue.8
, pp. 1379-1389
-
-
Welters, M.J.1
-
147
-
-
84903383252
-
Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants
-
Dubensky TW, Dubensky TW Jr, Kanne DB, Leong ML. Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants. Ther Adv Vaccines. 2013;1(4):131-143.
-
(2013)
Ther Adv Vaccines
, vol.1
, Issue.4
, pp. 131-143
-
-
Dubensky, T.W.1
Dubensky, T.W.2
Kanne, D.B.3
Leong, M.L.4
-
148
-
-
34547094098
-
Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells
-
Khan S, et al. Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells. J Biol Chem. 2007;282(29):21145-21159.
-
(2007)
J Biol Chem
, vol.282
, Issue.29
, pp. 21145-21159
-
-
Khan, S.1
-
149
-
-
84912075633
-
Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates
-
Zom GG, et al. Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates. Cancer Immunol Res. 2014;2(8):756-764.
-
(2014)
Cancer Immunol Res
, vol.2
, Issue.8
, pp. 756-764
-
-
Zom, G.G.1
-
150
-
-
84858767031
-
TLR ligand-peptide conjugate vaccines: Toward clinical application
-
Zom GG, Khan S, Filippov DV, Ossendorp F. TLR ligand-peptide conjugate vaccines: toward clinical application. Adv Immunol. 2012;114:177-201.
-
(2012)
Adv Immunol
, vol.114
, pp. 177-201
-
-
Zom, G.G.1
Khan, S.2
Filippov, D.V.3
Ossendorp, F.4
-
151
-
-
84921794613
-
MRNA-based therapeutics -developing a new class of drugs
-
Sahin U, Kariko K, Tureci O. mRNA-based therapeutics -developing a new class of drugs. Nat Rev Drug Discov. 2014;13(10):759-780.
-
(2014)
Nat Rev Drug Discov
, vol.13
, Issue.10
, pp. 759-780
-
-
Sahin, U.1
Kariko, K.2
Tureci, O.3
-
153
-
-
38449085650
-
Characterization of antigen-specific immune responses induced by canarypox virus vaccines
-
Bos R, et al. Characterization of antigen-specific immune responses induced by canarypox virus vaccines. J Immunol. 2007;179(9):6115-6122.
-
(2007)
J Immunol
, vol.179
, Issue.9
, pp. 6115-6122
-
-
Bos, R.1
-
154
-
-
84880730418
-
Selection of immunostimulant AS15 for active immunization with MAGE-A3 protein: Results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma
-
Kruit WH, et al. Selection of immunostimulant AS15 for active immunization with MAGE-A3 protein: results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma. J Clin Oncol. 2013;31(19):2413-2420.
-
(2013)
J Clin Oncol
, vol.31
, Issue.19
, pp. 2413-2420
-
-
Kruit, W.H.1
-
155
-
-
84880755387
-
Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: Phase II randomized study results
-
Vansteenkiste J, et al. Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results. J Clin Oncol. 2013;31(19):2396-2403.
-
(2013)
J Clin Oncol
, vol.31
, Issue.19
, pp. 2396-2403
-
-
Vansteenkiste, J.1
-
159
-
-
2442647551
-
Dendritic cell immunotherapy: Mapping the way
-
Figdor CG, de Vries IJ, Lesterhuis WJ, Melief CJ. Dendritic cell immunotherapy: mapping the way. Nat Med. 2004;10(5):475-480.
-
(2004)
Nat Med
, vol.10
, Issue.5
, pp. 475-480
-
-
Figdor, C.G.1
De Vries, I.J.2
Lesterhuis, W.J.3
Melief, C.J.4
-
160
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat Med. 2004;10(9):909-915.
-
(2004)
Nat Med
, vol.10
, Issue.9
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
161
-
-
84961291217
-
Persistence of CTL clones targeting melanocyte differentiation antigens was insufficient to mediate significant melanoma regression in humans
-
Chandran SS, et al. Persistence of CTL clones targeting melanocyte differentiation antigens was insufficient to mediate significant melanoma regression in humans. Clin Cancer Res. 2015;21(3):534-543.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.3
, pp. 534-543
-
-
Chandran, S.S.1
-
162
-
-
79957732443
-
Tumor vaccination using messenger RNA: Prospects of a future therapy
-
Kreiter S, Diken M, Selmi A, Tureci O, Sahin U. Tumor vaccination using messenger RNA: prospects of a future therapy. Curr Opin Immunol. 2011;23(3):399-406.
-
(2011)
Curr Opin Immunol
, vol.23
, Issue.3
, pp. 399-406
-
-
Kreiter, S.1
Diken, M.2
Selmi, A.3
Tureci, O.4
Sahin, U.5
-
163
-
-
84890147150
-
Exploiting the curative potential of adoptive T-cell therapy for cancer
-
Hinrichs CS, Rosenberg SA. Exploiting the curative potential of adoptive T-cell therapy for cancer. Immunol Rev. 2014;257(1):56-71.
-
(2014)
Immunol Rev
, vol.257
, Issue.1
, pp. 56-71
-
-
Hinrichs, C.S.1
Rosenberg, S.A.2
-
164
-
-
79959761214
-
Successful treatment of metastatic melanoma by adoptive transfer of blood-derived polyclonal tumor-specific CD4+ and CD8+ T cells in combination with low-dose interferon-α
-
Verdegaal EM, et al. Successful treatment of metastatic melanoma by adoptive transfer of blood-derived polyclonal tumor-specific CD4+ and CD8+ T cells in combination with low-dose interferon-α. Cancer Immunol Immunother. 2011;60(7):953-963.
-
(2011)
Cancer Immunol Immunother
, vol.60
, Issue.7
, pp. 953-963
-
-
Verdegaal, E.M.1
-
165
-
-
84901281224
-
Chemotherapeutic targeting of cancer-induced immunosuppressive cells
-
Alizadeh D, Larmonier N. Chemotherapeutic targeting of cancer-induced immunosuppressive cells. Cancer Res. 2014;74(10):2663-2668.
-
(2014)
Cancer Res
, vol.74
, Issue.10
, pp. 2663-2668
-
-
Alizadeh, D.1
Larmonier, N.2
-
166
-
-
84923138991
-
Vaccine-induced tumor necrosis factor-producing T cells synergize with Cisplatin to promote tumor cell death
-
van der Sluis TC, et al. Vaccine-induced tumor necrosis factor-producing T cells synergize with Cisplatin to promote tumor cell death. Clin Cancer Res. 2015;21(4):781-794.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.4
, pp. 781-794
-
-
Van Der Sluis, T.C.1
-
167
-
-
84905457466
-
Preclinical evidence that PD1 blockade cooperates with cancer vaccine TEGVAX to elicit regression of established tumors
-
Fu J, Malm IJ, Kadayakkara DK, Levitsky H, Pardoll D, Kim YJ. Preclinical evidence that PD1 blockade cooperates with cancer vaccine TEGVAX to elicit regression of established tumors. Cancer Res. 2014;74(15):4042-4052.
-
(2014)
Cancer Res
, vol.74
, Issue.15
, pp. 4042-4052
-
-
Fu, J.1
Malm, I.J.2
Kadayakkara, D.K.3
Levitsky, H.4
Pardoll, D.5
Kim, Y.J.6
-
168
-
-
84991038640
-
Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy
-
Mkrtichyan M, et al. Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy. J Immunother Cancer. 2013;1:15.
-
(2013)
J Immunother Cancer
, vol.1
, pp. 15
-
-
Mkrtichyan, M.1
-
169
-
-
84875689651
-
Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer
-
Wada S, et al. Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer. J Transl Med. 2013;11:89.
-
(2013)
J Transl Med
, vol.11
, pp. 89
-
-
Wada, S.1
-
170
-
-
79954579274
-
Local activation of CD8 T cells and systemic tumor eradication without toxicity via slow release and local delivery of agonistic CD40 antibody
-
Fransen MF, Sluijter M, Morreau H, Arens R, Melief CJ. Local activation of CD8 T cells and systemic tumor eradication without toxicity via slow release and local delivery of agonistic CD40 antibody. Clin Cancer Res. 2011;17(8):2270-2280.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.8
, pp. 2270-2280
-
-
Fransen, M.F.1
Sluijter, M.2
Morreau, H.3
Arens, R.4
Melief, C.J.5
-
171
-
-
84874845333
-
Agonistic CD40 antibodies and cancer therapy
-
Vonderheide RH, Glennie MJ. Agonistic CD40 antibodies and cancer therapy. Clin Cancer Res. 2013;19(5):1035-1043.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.5
, pp. 1035-1043
-
-
Vonderheide, R.H.1
Glennie, M.J.2
-
172
-
-
23944461007
-
Vaccination with dendritic cells pulsed with apoptotic tumors in combination with anti-OX40 and anti-4-1BB monoclonal antibodies induces T cell-mediated protective immunity in Her-2/neu transgenic mice
-
Cuadros C, et al. Vaccination with dendritic cells pulsed with apoptotic tumors in combination with anti-OX40 and anti-4-1BB monoclonal antibodies induces T cell-mediated protective immunity in Her-2/neu transgenic mice. Int J Cancer. 2005;116(6):934-943.
-
(2005)
Int J Cancer
, vol.116
, Issue.6
, pp. 934-943
-
-
Cuadros, C.1
-
173
-
-
8544249166
-
Anti-CD137 monoclonal antibody administration augments the antitumor efficacy of dendritic cell-based vaccines
-
Ito F, et al. Anti-CD137 monoclonal antibody administration augments the antitumor efficacy of dendritic cell-based vaccines. Cancer Res. 2004;64(22):8411-8419.
-
(2004)
Cancer Res
, vol.64
, Issue.22
, pp. 8411-8419
-
-
Ito, F.1
-
174
-
-
63449088194
-
Palettes of vaccines and immunostimulatory monoclonal antibodies for combination
-
Melero I, Martinez-Forero I, Dubrot J, Suarez N, Palazon A, Chen L. Palettes of vaccines and immunostimulatory monoclonal antibodies for combination. Clin Cancer Res. 2009;15(5):1507-1509.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.5
, pp. 1507-1509
-
-
Melero, I.1
Martinez-Forero, I.2
Dubrot, J.3
Suarez, N.4
Palazon, A.5
Chen, L.6
-
175
-
-
84874830056
-
Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types
-
Ascierto PA, Kalos M, Schaer DA, Callahan MK, Wolchok JD. Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types. Clin Cancer Res. 2013;19(5):1009-1020.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.5
, pp. 1009-1020
-
-
Ascierto, P.A.1
Kalos, M.2
Schaer, D.A.3
Callahan, M.K.4
Wolchok, J.D.5
-
176
-
-
84891275907
-
OX40 is a potent immune-stimulating target in late-stage cancer patients
-
Curti BD, et al. OX40 is a potent immune-stimulating target in late-stage cancer patients. Cancer Res. 2013;73(24):7189-7198.
-
(2013)
Cancer Res
, vol.73
, Issue.24
, pp. 7189-7198
-
-
Curti, B.D.1
-
177
-
-
84885466006
-
Agonist anti-human CD27 monoclonal antibody induces T cell activation and tumor immunity in human CD27-Transgenic mice
-
He LZ, et al. Agonist anti-human CD27 monoclonal antibody induces T cell activation and tumor immunity in human CD27-Transgenic mice. J Immunol. 2013;191(8):4174-4183.
-
(2013)
J Immunol
, vol.191
, Issue.8
, pp. 4174-4183
-
-
He, L.Z.1
-
178
-
-
84975070417
-
Anti-CD27 antibody potentiates antitumor effect of dendritic cell-based vaccine in prostate cancer-bearing mice
-
Wei SM, et al. Anti-CD27 antibody potentiates antitumor effect of dendritic cell-based vaccine in prostate cancer-bearing mice. Int Surg. 2015;100(1):155-163.
-
(2015)
Int Surg
, vol.100
, Issue.1
, pp. 155-163
-
-
Wei, S.M.1
-
179
-
-
54249148553
-
Balancing between antitumor efficacy and autoimmune pathology in T-cellmediated targeting of carcinoembryonic antigen
-
Bos R, et al. Balancing between antitumor efficacy and autoimmune pathology in T-cellmediated targeting of carcinoembryonic antigen. Cancer Res. 2008;68(20):8446-8455.
-
(2008)
Cancer Res
, vol.68
, Issue.20
, pp. 8446-8455
-
-
Bos, R.1
-
180
-
-
84904241508
-
Anti-interleukin-10R1 monoclonal antibody in combination with bacillus Calmette -Guerin is protective against bladder cancer metastasis in a murine orthotopic tumour model and demonstrates systemic specific anti-Tumour immunity
-
Newton MR, et al. Anti-interleukin-10R1 monoclonal antibody in combination with bacillus Calmette -Guerin is protective against bladder cancer metastasis in a murine orthotopic tumour model and demonstrates systemic specific anti-Tumour immunity. Clin Exp Immunol. 2014;177(1):261-268.
-
(2014)
Clin Exp Immunol
, vol.177
, Issue.1
, pp. 261-268
-
-
Newton, M.R.1
-
181
-
-
84883493454
-
Tumors as organs: Biologically augmenting radiation therapy by inhibiting transforming growth factor beta activity in carcinomas
-
Du S, Barcellos-Hoff MH. Tumors as organs: biologically augmenting radiation therapy by inhibiting transforming growth factor beta activity in carcinomas. Semin Radiat Oncol. 2013;23(4):242-251.
-
(2013)
Semin Radiat Oncol
, vol.23
, Issue.4
, pp. 242-251
-
-
Du, S.1
Barcellos-Hoff, M.H.2
-
182
-
-
84903712933
-
TGF-β signaling in cancer treatment
-
Fabregat I, Fernando J, Mainez J, Sancho P. TGF-β signaling in cancer treatment. Curr Pharm Des. 2014;20(17):2934-2947.
-
(2014)
Curr Pharm des
, vol.20
, Issue.17
, pp. 2934-2947
-
-
Fabregat, I.1
Fernando, J.2
Mainez, J.3
Sancho, P.4
-
183
-
-
77954951446
-
The polarization of immune cells in the tumour environment by TGFβ
-
Flavell RA, Sanjabi S, Wrzesinski SH, Licona-Limon P. The polarization of immune cells in the tumour environment by TGFβ. Nat Rev Immunol. 2010;10(8):554-567.
-
(2011)
Nat Rev Immunol
, vol.10
, Issue.8
, pp. 554-567
-
-
Flavell, R.A.1
Sanjabi, S.2
Wrzesinski, S.H.3
Licona-Limon, P.4
-
184
-
-
84941653574
-
Adaptive upregulation of EGFR limits attenuation of tumor growth by neutralizing IL-6 antibodies with implications for combined therapy in ovarian cancer
-
Milagre CS, et al. Adaptive upregulation of EGFR limits attenuation of tumor growth by neutralizing IL-6 antibodies with implications for combined therapy in ovarian cancer. Cancer Res. 2015;75(7):1255-1264.
-
(2015)
Cancer Res
, vol.75
, Issue.7
, pp. 1255-1264
-
-
Milagre, C.S.1
-
185
-
-
84904617950
-
The biology and medical implications of interleukin-6
-
Tanaka T, Kishimoto T. The biology and medical implications of interleukin-6. Cancer Immunol Res. 2014;2(4):288-294.
-
(2014)
Cancer Immunol Res
, vol.2
, Issue.4
, pp. 288-294
-
-
Tanaka, T.1
Kishimoto, T.2
-
186
-
-
84907979458
-
The IL-2 cytokine family in cancer immunotherapy
-
Sim GC, Radvanyi L. The IL-2 cytokine family in cancer immunotherapy. Cytokine Growth Factor Rev. 2014;25(4):377-390.
-
(2014)
Cytokine Growth Factor Rev
, vol.25
, Issue.4
, pp. 377-390
-
-
Sim, G.C.1
Radvanyi, L.2
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