The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Pearson, Helen B ^a,b   McGlinn, Edwina ^c   Phesse, Toby J ^d,e   Schlüter, Holger ^a,f   Srikumar, Anuratha ^a   Gödde, Nathan J ^a   Woelwer, Christina B ^a   Ryan, Andrew ^g   Phillips, Wayne A ^a,b   Ernst, Matthias ^d,e   Kaur, Pritinder ^a,b   Humbert, Patrick ^a,b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c Monash University   (Australia)

^d WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e LA TROBE UNIVERSITY   (Australia)

^f GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^g Tissupath Pty Ltd   (Australia)

Author keywords

Carcinogenesis; Permeability barrier; Polarity; Scrib; Skin

Indexed keywords

ALCIAN BLUE; ALIZARIN; PROTEIN; SCRIB PROTEIN; TOLUIDINE DERIVATIVE; UNCLASSIFIED DRUG; CRE RECOMBINASE; INTEGRASE; SCRIBBLE PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL MATURATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EMBRYO; EMBRYO DEVELOPMENT; EPIDERMAL DEVELOPMENT; HETEROZYGOSITY; HOMEOSTASIS; IN VIVO STUDY; KERATINOCYTE; MORPHOGENESIS; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PROTEIN FUNCTION; SKIN CARCINOGENESIS; SKIN PERMEABILITY; WILD TYPE; ANIMAL; CELL DIFFERENTIATION; CELL POLARITY; DISEASE MODEL; EPIDERMIS; EPITHELIUM CELL; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; KNOCKOUT MOUSE; MAMMALIAN EMBRYO; METABOLISM; PATHOLOGY; SKIN TUMOR; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOGENESIS; CELL DIFFERENTIATION; CELL POLARITY; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; EPIDERMIS; EPITHELIAL CELLS; GENES, TUMOR SUPPRESSOR; HUMANS; INTEGRASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATINOCYTES; MICE; MICE, KNOCKOUT; SKIN NEOPLASMS;

EID: 84941632980     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0440-z     Document Type: Article

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