Circletail, a new mouse mutant with severe neural tube defects: Chromosomal localization and interaction with the loop-tail mutation

Genomics

Volumn 78, Issue 1-2, 2001, Pages 55-63

  Murdoch, Jennifer N ^a   Rachel, Rivka A ^b   Shah, Saima ^a   Beermann, Friedrich ^c   Stanier, Philip ^d   Mason, Carol A ^b   Copp, Andrew J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Columbia University ^*  (United States)

^c SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^d IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Chromosome 15; Craniorachischisis; Crc; Gene interactions; Linkage analysis; Lp; Ltap; Neurulation; NTD

Indexed keywords

GENE PRODUCT;

ALLELE; ANIMAL MODEL; ARTICLE; CHROMOSOMAL LOCALIZATION; CONTROLLED STUDY; DISEASE SEVERITY; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GENETIC COMPLEMENTATION; GENETIC LINKAGE; HETEROZYGOSITY; MARKER GENE; MOUSE; MOUSE MUTANT; NEURAL TUBE DEFECT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANIMALIA;

EID: 0034756121     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2001.6638     Document Type: Article

References (25)

1. Intermittent pattern of neural tube closure in two strains of mice
2. Etiology and pathogenesis of human neural tube defects: Insights from mouse models
3. The embryonic development of mammalian neural tube defects
4. Developmental basis of severe neural tube defects in the loop-tail (Lp) mutant mouse: Use of microsatellite DNA markers to identify embryonic genotype
5. Mechanisms of normal and abnormal neurulation: Evidence from embryo culture studies
6. Genetic landmarks for defects in mouse neural tube closure
7. Mini-review: Toward understanding mechanisms of genetic neural tube defects in mice
8. Mouse models for neural tube closure defects
9. Hereditary, loop-tail in the house mouse
10. Genetic basis of neural tube defects: The mouse gene loop-tail maps to a region of chromosome 1 syntenic with human 1q21-q23
11. High-resolution linkage map in the vicinity of the Lp locus
12. Physical and transcriptional map of a three megabase region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp)
13. Physical delineation of a 700-kb region overlapping the Looptail mutation on mouse chromosome 1
14. Comparative physical and transcript maps of -1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23
15. Ltap, a mammalian homologue of Drosophila Stabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail
16. Retinal axon misrouting at the optic chiasm in mice with neural tube closure defects
17. A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic mice
18. A comprehensive genetic map of the mouse genome
19. A high resolution map of the mouse genome
20. A genetic map of the mouse suitable for typing intraspecific crosses
21. Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: A model of severe neural tube defects
22. Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B
23. Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand