메뉴 건너뛰기




Volumn 15, Issue 9, 2013, Pages 741-746

Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression

Author keywords

Apoptosis; BCL 2; miR 21; Pancreatic cancer; Resveratrol

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; MICRORNA 21; PROTEIN BCL 2; RESVERATROL;

EID: 84883297845     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-012-0999-4     Document Type: Article
Times cited : (116)

References (22)
  • 1
    • 30544442177 scopus 로고    scopus 로고
    • Front-line therapy of advanced pancreatic cancer
    • 16399428 10.1053/j.seminoncol.2005.06.007 1:CAS:528:DC%2BD28XhtFChurs%3D
    • Kindler HL (2005) Front-line therapy of advanced pancreatic cancer. Semin Oncol 32:S33-S36
    • (2005) Semin Oncol , vol.32
    • Kindler, H.L.1
  • 2
    • 43549088782 scopus 로고    scopus 로고
    • Resveratrol: A multitargeted agent for age-associated chronic diseases
    • 18414053 10.4161/cc.7.8.5740 1:CAS:528:DC%2BD1cXnvVSrsLY%3D
    • Harikumar KB, Aggarwal BB (2008) Resveratrol: a multitargeted agent for age-associated chronic diseases. Cell Cycle 7:1020-1035
    • (2008) Cell Cycle , vol.7 , pp. 1020-1035
    • Harikumar, K.B.1    Aggarwal, B.B.2
  • 3
    • 77956716582 scopus 로고    scopus 로고
    • Dietary polyphenols: Focus on resveratrol, a promising agent in the prevention of cardiovascular diseases and control of glucose homeostasis
    • 20850033 10.1016/j.numecd.2010.07.004 1:CAS:528:DC%2BC3cXhtFyis7bO
    • Borriello A, Cucciolla V, Della Raqione F, Galletti P (2010) Dietary polyphenols: focus on resveratrol, a promising agent in the prevention of cardiovascular diseases and control of glucose homeostasis. Nutr Metab Cardiovasc Dis 20:618-625
    • (2010) Nutr Metab Cardiovasc Dis , vol.20 , pp. 618-625
    • Borriello, A.1    Cucciolla, V.2    Della Raqione, F.3    Galletti, P.4
  • 4
    • 75149192820 scopus 로고    scopus 로고
    • Sirtuins as novel targets for Alzheimer's disease and other neurodegenerative disorders: Experimental and genetic evidence
    • 20061622
    • Albani D, Polito L, Forloni G (2010) Sirtuins as novel targets for Alzheimer's disease and other neurodegenerative disorders: experimental and genetic evidence. J Alzheimers Dis 19:11-26
    • (2010) J Alzheimers Dis , vol.19 , pp. 11-26
    • Albani, D.1    Polito, L.2    Forloni, G.3
  • 5
    • 80053199541 scopus 로고    scopus 로고
    • Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors
    • 21980390 10.1371/journal.pone.0025166 1:CAS:528:DC%2BC3MXhtlCjsr%2FF
    • Roy SK, Chen Q, Fu J, Shankar S, Srivastava RK (2011) Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors. PLoS One 6(9):e25166
    • (2011) PLoS One , vol.6 , Issue.9 , pp. 25166
    • Roy, S.K.1    Chen, Q.2    Fu, J.3    Shankar, S.4    Srivastava, R.K.5
  • 6
    • 79957880105 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis in pancreatic cancer cells
    • 1:CAS:528:DC%2BC3MXps1Ontr8%3D
    • Zhou JH, Cheng HY, Yu ZQ, He DW, Pan Z, Yang DT (2011) Resveratrol induces apoptosis in pancreatic cancer cells. Chin Med J (Engl) 124(11):1695-1699
    • (2011) Chin Med J (Engl) , vol.124 , Issue.11 , pp. 1695-1699
    • Zhou, J.H.1    Cheng, H.Y.2    Yu, Z.Q.3    He, D.W.4    Pan, Z.5    Yang, D.T.6
  • 7
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • 14744438 10.1016/S0092-8674(04)00045-5 1:CAS:528:DC%2BD2cXhtVals7o%3D
    • Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 8
    • 61849137222 scopus 로고    scopus 로고
    • Many roads to maturity: MicroRNA biogenesis pathways and their regulation
    • 19255566 10.1038/ncb0309-228 1:CAS:528:DC%2BD1MXisVOltrg%3D
    • Winter J, Jung S, Keller S, Gregory RI, Diederich S (2009) Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol 11(3):228-234
    • (2009) Nat Cell Biol , vol.11 , Issue.3 , pp. 228-234
    • Winter, J.1    Jung, S.2    Keller, S.3    Gregory, R.I.4    Diederich, S.5
  • 9
    • 77957721534 scopus 로고    scopus 로고
    • Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cells
    • 20637737 10.1016/j.bcp.2010.07.003 1:CAS:528:DC%2BC3cXhtlKrs7zM
    • Tili E, Michaille JJ, Alder H, Volinia S, Delmas D, Latruffe N, Croce CM (2010) Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cells. Biochem Pharmacol 80(12):2057-2065
    • (2010) Biochem Pharmacol , vol.80 , Issue.12 , pp. 2057-2065
    • Tili, E.1    Michaille, J.J.2    Alder, H.3    Volinia, S.4    Delmas, D.5    Latruffe, N.6    Croce, C.M.7
  • 10
    • 84864686727 scopus 로고    scopus 로고
    • Feasibility of fecal MicroRNAs as novel biomarkers for pancreatic cancer
    • 22905187 10.1371/journal.pone.0042933 1:CAS:528:DC%2BC38Xht1SnsLvK
    • Link A, Becker V, Goel A, Wex T, Malfertheiner P (2012) Feasibility of fecal MicroRNAs as novel biomarkers for pancreatic cancer. PLoS One 7(8):e42933
    • (2012) PLoS One , vol.7 , Issue.8 , pp. 42933
    • Link, A.1    Becker, V.2    Goel, A.3    Wex, T.4    Malfertheiner, P.5
  • 12
    • 77954668084 scopus 로고    scopus 로고
    • Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis
    • 20646298 10.1186/1471-2407-10-379
    • Rückert F, Samm N, Lehner AK, Saeger HD, Grützmann R, Pilarsky C (2010) Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis. BMC Cancer 10:379
    • (2010) BMC Cancer , vol.10 , pp. 379
    • Rückert, F.1    Samm, N.2    Lehner, A.K.3    Saeger, H.D.4    Grützmann, R.5    Pilarsky, C.6
  • 13
    • 79952075732 scopus 로고    scopus 로고
    • Bcl-2 upregulation induced by miR-21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa-2 pancreatic cancer cells
    • 21376256 10.1016/j.arcmed.2011.01.006 1:CAS:528:DC%2BC3MXjs1Wlt7Y%3D
    • Dong J, Zhao YP, Zhou L, Zhang TP, Chen G (2011) Bcl-2 upregulation induced by miR-21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa-2 pancreatic cancer cells. Arch Med Res 42(1):8-14
    • (2011) Arch Med Res , vol.42 , Issue.1 , pp. 8-14
    • Dong, J.1    Zhao, Y.P.2    Zhou, L.3    Zhang, T.P.4    Chen, G.5
  • 14
    • 70449631049 scopus 로고    scopus 로고
    • Islet neogenesis-associated protein-related pentadeca peptide enhances the differentiation of islet-like clusters from human pancreatic duct cells
    • 19747955 10.1016/j.peptides.2009.09.003 1:CAS:528:DC%2BD1MXhsVKntL3J
    • Li J, Wang Y, Yu X, Chen H, Wu Y, Han X, Guo X, Zhang C, Chen Q, Chen J, Yang T (2009) Islet neogenesis-associated protein-related pentadeca peptide enhances the differentiation of islet-like clusters from human pancreatic duct cells. Peptides 30:2242-2249
    • (2009) Peptides , vol.30 , pp. 2242-2249
    • Li, J.1    Wang, Y.2    Yu, X.3    Chen, H.4    Wu, Y.5    Han, X.6    Guo, X.7    Zhang, C.8    Chen, Q.9    Chen, J.10    Yang, T.11
  • 15
    • 1042304324 scopus 로고    scopus 로고
    • Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2¢-deoxyuridine
    • 14716816 1:CAS:528:DC%2BD2cXhsVOku7o%3D
    • Ma T, Zhu ZG, Ji YB et al (2004) Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2¢- deoxyuridine. World J Gastroenterol 10:172-176
    • (2004) World J Gastroenterol , vol.10 , pp. 172-176
    • Ma, T.1    Zhu, Z.G.2    Ji, Y.B.3
  • 16
    • 0034699433 scopus 로고    scopus 로고
    • Flow cytometry of apoptotic cell death
    • 10986414 10.1016/S0022-1759(00)00233-7 1:CAS:528:DC%2BD3cXmtlGlu7k%3D
    • Vermes I, Haanen C, Reutelingsperger C (2000) Flow cytometry of apoptotic cell death. J Immunol Methods 243:167-190
    • (2000) J Immunol Methods , vol.243 , pp. 167-190
    • Vermes, I.1    Haanen, C.2    Reutelingsperger, C.3
  • 18
    • 84862781019 scopus 로고    scopus 로고
    • Resveratrol inhibits proliferation and induces apoptosis through the hedgehog signaling pathway in pancreatic cancer cell
    • 22301921 10.1159/000333542 1:CAS:528:DC%2BC38XivVClsbY%3D
    • Mo W, Xu X, Xu L, Wang F, Ke A, Wang X, Guo C (2011) Resveratrol inhibits proliferation and induces apoptosis through the hedgehog signaling pathway in pancreatic cancer cell. Pancreatology 11(6):601-609
    • (2011) Pancreatology , vol.11 , Issue.6 , pp. 601-609
    • Mo, W.1    Xu, X.2    Xu, L.3    Wang, F.4    Ke, A.5    Wang, X.6    Guo, C.7
  • 19
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • 16732220 10.1038/nrd2060 1:CAS:528:DC%2BD28XlsV2jur8%3D
    • Baur JA, Sinclair DA (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5(6):493-506
    • (2006) Nat Rev Drug Discov , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 20
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • 20098459 10.1038/nri2708
    • O'Connell RM, Rao DS, Chaudhuri AA, Baltimore D (2010) Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol 10(2):111-122
    • (2010) Nat Rev Immunol , vol.10 , Issue.2 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 21
    • 79959315095 scopus 로고    scopus 로고
    • Apoptosis and the target genes of microRNA-21
    • 21627859
    • Buscaglia LE, Li Y (2011) Apoptosis and the target genes of microRNA-21. Chin J Cancer 30(6):371-380
    • (2011) Chin J Cancer , vol.30 , Issue.6 , pp. 371-380
    • Buscaglia, L.E.1    Li, Y.2
  • 22
    • 77956178738 scopus 로고    scopus 로고
    • MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity
    • 20633539 10.1016/j.brainres.2010.07.009 1:CAS:528:DC%2BC3cXhtVKisLnE
    • Shi L, Chen J, Yang J, Pan T, Zhang S, Wang Z (2010) MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity. Brain Res 1352:255-264
    • (2010) Brain Res , vol.1352 , pp. 255-264
    • Shi, L.1    Chen, J.2    Yang, J.3    Pan, T.4    Zhang, S.5    Wang, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.