▵F508 CFTR surface stability is regulated by DAB2 and CHIP-mediated ubiquitination in post-endocytic compartments

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Fu, Lianwu ^a,c   Rab, Andras ^a,c   Tang, Li Ping ^b,c   Bebok, Zsuzsa ^a,c   Rowe, Steven M ^b,c   Bartoszewski, Rafal ^d   Collawn, James F ^a,c  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CBL PROTEIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; LUMACAFTOR; PROTEIN CHIP; PROTEIN DAB2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 2; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE NEDD4; UBIQUITIN PROTEIN LIGASE NEDD4-2; UNCLASSIFIED DRUG; CFTR PROTEIN, HUMAN; CHI PROTEIN, DROSOPHILA; DAB2 PROTEIN, HUMAN; DROSOPHILA PROTEIN; NUCLEAR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BIOTINYLATION; CELL SURFACE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTERNALIZATION; LOW TEMPERATURE; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN STABILITY; RESPIRATORY EPITHELIUM; UBIQUITINATION; WESTERN BLOTTING; CELL CULTURE; CHEMISTRY; GENETICS; METABOLISM; PHYSIOLOGY; SURFACE PROPERTY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELLS, CULTURED; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DROSOPHILA PROTEINS; ENDOCYTOSIS; HUMANS; NUCLEAR PROTEINS; RNA, SMALL INTERFERING; SURFACE PROPERTIES; TUMOR SUPPRESSOR PROTEINS; UBIQUITINATION;

EID: 84928494186     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0123131     Document Type: Article

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