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Volumn 290, Issue 37, 2015, Pages 22805-22817

Dual role of superoxide dismutase 2 induced in activated microglia: Oxidative stress tolerance and convergence of inflammatory responses

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; OLIGONUCLEOTIDES; OXYGEN;

EID: 84941584670     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.659151     Document Type: Article
Times cited : (80)

References (56)
  • 1
    • 67650432423 scopus 로고    scopus 로고
    • Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: A time course study in a 6-hydroxydopamine model of Parkinson's disease
    • Marinova-Mutafchieva, L., Sadeghian, M., Broom, L., Davis, J. B., Medhurst, A. D., and Dexter, D. T. (2009) Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson's disease. J. Neurochem. 110, 966-975
    • (2009) J. Neurochem. , vol.110 , pp. 966-975
    • Marinova-Mutafchieva, L.1    Sadeghian, M.2    Broom, L.3    Davis, J.B.4    Medhurst, A.D.5    Dexter, D.T.6
  • 2
    • 51149120624 scopus 로고    scopus 로고
    • Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice
    • Hickman, S. E., Allison, E. K., and El Khoury, J. (2008) Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice. J. Neurosci. 28, 8354-8360
    • (2008) J. Neurosci. , vol.28 , pp. 8354-8360
    • Hickman, S.E.1    Allison, E.K.2    El Khoury, J.3
  • 3
    • 80053606159 scopus 로고    scopus 로고
    • Toll-like receptors in cerebral ischemic inflammatory injury
    • Wang, Y. C., Lin, S., and Yang, Q. W. (2011) Toll-like receptors in cerebral ischemic inflammatory injury. J. Neuroinflammation 8, 134
    • (2011) J. Neuroinflammation , vol.8 , pp. 134
    • Wang, Y.C.1    Lin, S.2    Yang, Q.W.3
  • 5
    • 84890986568 scopus 로고    scopus 로고
    • Neurogenic neuroinflammation: Inflammatory CNS reactions in response to neuronal activity
    • Xanthos, D. N., and Sandkühler, J. (2014) Neurogenic neuroinflammation: inflammatory CNS reactions in response to neuronal activity. Nat. Rev. Neurosci. 15, 43-53
    • (2014) Nat. Rev. Neurosci. , vol.15 , pp. 43-53
    • Xanthos, D.N.1    Sandkühler, J.2
  • 6
    • 24144453087 scopus 로고    scopus 로고
    • Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
    • Block, M. L., and Hong, J. S. (2005) Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog. Neurobiol. 76, 77-98
    • (2005) Prog. Neurobiol. , vol.76 , pp. 77-98
    • Block, M.L.1    Hong, J.S.2
  • 7
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • Bedard, K., and Krause, K. H. (2007) The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 87, 245-313
    • (2007) Physiol. Rev. , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 9
    • 0016641412 scopus 로고
    • An isotopic assay for NADPH oxidase activity and some characteristics of the enzyme from human polymorphonuclear leukocytes
    • DeChatelet, L. R., McPhail, L. C., Mullikin, D., and McCall, C. E. (1975) An isotopic assay for NADPH oxidase activity and some characteristics of the enzyme from human polymorphonuclear leukocytes. J. Clin. Invest. 55, 714-721
    • (1975) J. Clin. Invest. , vol.55 , pp. 714-721
    • DeChatelet, L.R.1    McPhail, L.C.2    Mullikin, D.3    McCall, C.E.4
  • 10
    • 84898056697 scopus 로고    scopus 로고
    • Subneurotoxic copper (II)-induced NF-κB-dependent microglial activation is associated with mitochondrial ROS
    • Hu, Z., Yu, F., Gong, P., Qiu, Y., Zhou, W., Cui, Y., Li, J., and Chen, H. (2014) Subneurotoxic copper (II)-induced NF-κB-dependent microglial activation is associated with mitochondrial ROS. Toxicol. Appl. Pharmacol. 276, 95-103
    • (2014) Toxicol. Appl. Pharmacol. , vol.276 , pp. 95-103
    • Hu, Z.1    Yu, F.2    Gong, P.3    Qiu, Y.4    Zhou, W.5    Cui, Y.6    Li, J.7    Chen, H.8
  • 11
    • 84875211266 scopus 로고    scopus 로고
    • Inflammatory response of microglial BV-2 cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein 75/mortalin
    • Voloboueva, L. A., Emery, J. F., Sun, X., and Giffard, R. G. (2013) Inflammatory response of microglial BV-2 cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein 75/mortalin. FEBS Lett. 587, 756-762
    • (2013) FEBS Lett. , vol.587 , pp. 756-762
    • Voloboueva, L.A.1    Emery, J.F.2    Sun, X.3    Giffard, R.G.4
  • 12
    • 79952712223 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species drive proinflammatory cytokine production
    • Naik, E., and Dixit, V. M. (2011) Mitochondrial reactive oxygen species drive proinflammatory cytokine production. J. Exp. Med. 208, 417-420
    • (2011) J. Exp. Med. , vol.208 , pp. 417-420
    • Naik, E.1    Dixit, V.M.2
  • 14
    • 3442888512 scopus 로고    scopus 로고
    • Redox regulation of glial inflammatory response to lipopolysaccharide and interferongamma
    • Pawate, S., Shen, Q., Fan, F., and Bhat, N. R. (2004) Redox regulation of glial inflammatory response to lipopolysaccharide and interferongamma. J. Neurosci. Res. 77, 540-551
    • (2004) J. Neurosci. Res. , vol.77 , pp. 540-551
    • Pawate, S.1    Shen, Q.2    Fan, F.3    Bhat, N.R.4
  • 15
    • 0346463000 scopus 로고    scopus 로고
    • NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia
    • Qin, L., Liu, Y., Wang, T., Wei, S. J., Block, M. L., Wilson, B., Liu, B., and Hong, J. S. (2004) NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. J. Biol. Chem. 279, 1415-1421
    • (2004) J. Biol. Chem. , vol.279 , pp. 1415-1421
    • Qin, L.1    Liu, Y.2    Wang, T.3    Wei, S.J.4    Block, M.L.5    Wilson, B.6    Liu, B.7    Hong, J.S.8
  • 17
    • 4644350365 scopus 로고    scopus 로고
    • Cutting edge: Direct interaction of TLR4 with NAD (P) H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-κB
    • Park, H. S., Jung, H. Y., Park, E. Y., Kim, J., Lee, W. J., and Bae, Y. S. (2004) Cutting edge: direct interaction of TLR4 with NAD (P) H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-κB. J. Immunol. 173, 3589-3593
    • (2004) J. Immunol. , vol.173 , pp. 3589-3593
    • Park, H.S.1    Jung, H.Y.2    Park, E.Y.3    Kim, J.4    Lee, W.J.5    Bae, Y.S.6
  • 18
    • 84876463910 scopus 로고    scopus 로고
    • NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration
    • Qin, L., Liu, Y., Hong, J. S., and Crews, F. T. (2013) NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration. Glia 61, 855-868
    • (2013) Glia , vol.61 , pp. 855-868
    • Qin, L.1    Liu, Y.2    Hong, J.S.3    Crews, F.T.4
  • 19
    • 0037338145 scopus 로고    scopus 로고
    • Vitamin E (α-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia
    • Egger, T., Schuligoi, R., Wintersperger, A., Amann, R., Malle, E., and Sattler, W. (2003) Vitamin E (α-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia. Biochem. J. 370, 459-467
    • (2003) Biochem. J. , vol.370 , pp. 459-467
    • Egger, T.1    Schuligoi, R.2    Wintersperger, A.3    Amann, R.4    Malle, E.5    Sattler, W.6
  • 20
    • 0032006643 scopus 로고    scopus 로고
    • Vitamin E induces ramification and downregulation of adhesion molecules in cultured microglial cells
    • Heppner, F. L., Roth, K., Nitsch, R., and Hailer, N. P. (1998) Vitamin E induces ramification and downregulation of adhesion molecules in cultured microglial cells. Glia 22, 180-188
    • (1998) Glia , vol.22 , pp. 180-188
    • Heppner, F.L.1    Roth, K.2    Nitsch, R.3    Hailer, N.P.4
  • 21
    • 1542710617 scopus 로고    scopus 로고
    • α-Tocopherol reduces lipopolysaccharide-induced peroxide radical formation and interleukin-6 secretion in primary murine microglia and in brain
    • Godbout, J. P., Berg, B. M., Kelley, K. W., and Johnson, R. W. (2004) α-Tocopherol reduces lipopolysaccharide-induced peroxide radical formation and interleukin-6 secretion in primary murine microglia and in brain. J. Neuroimmunol. 149, 101-109
    • (2004) J. Neuroimmunol. , vol.149 , pp. 101-109
    • Godbout, J.P.1    Berg, B.M.2    Kelley, K.W.3    Johnson, R.W.4
  • 22
    • 0035888177 scopus 로고    scopus 로고
    • Vitamin E suppression of microglial activation is neuroprotective
    • Li, Y., Liu, L., Barger, S. W., Mrak, R. E., and Griffin, W. S. (2001) Vitamin E suppression of microglial activation is neuroprotective. J. Neurosci. Res. 66, 163-170
    • (2001) J. Neurosci. Res. , vol.66 , pp. 163-170
    • Li, Y.1    Liu, L.2    Barger, S.W.3    Mrak, R.E.4    Griffin, W.S.5
  • 23
    • 0032528291 scopus 로고    scopus 로고
    • Indicators of glial activation and brain oxidative stress after intraventricular infusion of endotoxin
    • Sugaya, K., Chou, S., Xu, S. J., and McKinney, M. (1998) Indicators of glial activation and brain oxidative stress after intraventricular infusion of endotoxin. Brain Res. Mol. Brain Res. 58, 1-9
    • (1998) Brain Res. Mol. Brain Res. , vol.58 , pp. 1-9
    • Sugaya, K.1    Chou, S.2    Xu, S.J.3    McKinney, M.4
  • 24
    • 0036775636 scopus 로고    scopus 로고
    • Lipopolysaccharide prevents cell death caused by glutathione depletion: Possible mechanisms of protection
    • Kramer, B. C., Yabut, J. A., Cheong, J., JnoBaptiste, R., Robakis, T., Olanow, C. W., and Mytilineou, C. (2002) Lipopolysaccharide prevents cell death caused by glutathione depletion: possible mechanisms of protection. Neuroscience 114, 361-372
    • (2002) Neuroscience , vol.114 , pp. 361-372
    • Kramer, B.C.1    Yabut, J.A.2    Cheong, J.3    JnoBaptiste, R.4    Robakis, T.5    Olanow, C.W.6    Mytilineou, C.7
  • 26
    • 0030697544 scopus 로고    scopus 로고
    • Induction of manganese superoxide dismutase in BV-2 microglial cells
    • Sugaya, K., Chouinard, M. L., and McKinney, M. (1997) Induction of manganese superoxide dismutase in BV-2 microglial cells. Neuroreport 8, 3547-3551
    • (1997) Neuroreport , vol.8 , pp. 3547-3551
    • Sugaya, K.1    Chouinard, M.L.2    McKinney, M.3
  • 27
    • 63049085420 scopus 로고    scopus 로고
    • Pretreatment with interferon-γ protects microglia from oxidative stress via up-regulation of Mn-SOD
    • Chen, X., Choi, I. Y., Chang, T. S., Noh, Y. H., Shin, C. Y., Wu, C. F., Ko, K. H., and Kim, W. K. (2009) Pretreatment with interferon-γ protects microglia from oxidative stress via up-regulation of Mn-SOD. Free Radic. Biol. Med. 46, 1204-1210
    • (2009) Free Radic. Biol. Med. , vol.46 , pp. 1204-1210
    • Chen, X.1    Choi, I.Y.2    Chang, T.S.3    Noh, Y.H.4    Shin, C.Y.5    Wu, C.F.6    Ko, K.H.7    Kim, W.K.8
  • 28
    • 84908454946 scopus 로고    scopus 로고
    • Selective estrogenreceptor modulators suppress microglial activation and neuronal cell death via an estrogen receptor-dependent pathway
    • Ishihara, Y., Itoh, K., Ishida, A., and Yamazaki, T. (2015) Selective estrogenreceptor modulators suppress microglial activation and neuronal cell death via an estrogen receptor-dependent pathway. J. Steroid Biochem. Mol. Biol. 145, 85-93
    • (2015) J. Steroid Biochem. Mol. Biol. , vol.145 , pp. 85-93
    • Ishihara, Y.1    Itoh, K.2    Ishida, A.3    Yamazaki, T.4
  • 29
    • 84861122953 scopus 로고    scopus 로고
    • Tributyltin induces oxidative stress and neuronal injury by inhibiting glutathione Stransferase in rat organotypic hippocampal slice cultures
    • Ishihara, Y., Kawami, T., Ishida, A., and Yamazaki, T. (2012) Tributyltin induces oxidative stress and neuronal injury by inhibiting glutathione Stransferase in rat organotypic hippocampal slice cultures. Neurochem. Int. 60, 782-790
    • (2012) Neurochem. Int. , vol.60 , pp. 782-790
    • Ishihara, Y.1    Kawami, T.2    Ishida, A.3    Yamazaki, T.4
  • 30
    • 0026653470 scopus 로고
    • Anovel monoclonal antibody against carbohydrates of L1 cell adhesion molecule causes an influx of calcium in cultured cortical neurons
    • Itoh, K., Kawamura, H., and Asou, H. (1992) Anovel monoclonal antibody against carbohydrates of L1 cell adhesion molecule causes an influx of calcium in cultured cortical neurons. Brain Res. 580, 233-240
    • (1992) Brain Res. , vol.580 , pp. 233-240
    • Itoh, K.1    Kawamura, H.2    Asou, H.3
  • 31
    • 84941562905 scopus 로고    scopus 로고
    • Neuroprotection elicited by nerve growth factor and brain-derived neurotrophic factor released from astrocytes in response to methylmercury
    • Takemoto, T., Ishihara, Y., Ishida, A., and Yamazaki, T. (2015) Neuroprotection elicited by nerve growth factor and brain-derived neurotrophic factor released from astrocytes in response to methylmercury. Environ. Toxicol. Pharmacol. 40, 199-205
    • (2015) Environ. Toxicol. Pharmacol. , vol.40 , pp. 199-205
    • Takemoto, T.1    Ishihara, Y.2    Ishida, A.3    Yamazaki, T.4
  • 32
    • 84896728912 scopus 로고    scopus 로고
    • Suppressive effects of 17β-estradiol on tributyltin-induced neuronal injury via Akt activation and subsequent attenuation of oxidative stress
    • Ishihara, Y., Fujitani, N., Kawami, T., Adachi, C., Ishida, A., and Yamazaki, T. (2014) Suppressive effects of 17β-estradiol on tributyltin-induced neuronal injury via Akt activation and subsequent attenuation of oxidative stress. Life Sci. 99, 24-30
    • (2014) Life Sci. , vol.99 , pp. 24-30
    • Ishihara, Y.1    Fujitani, N.2    Kawami, T.3    Adachi, C.4    Ishida, A.5    Yamazaki, T.6
  • 33
    • 33745864853 scopus 로고    scopus 로고
    • Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition
    • Ishihara, Y., Shiba, D., and Shimamoto, N. (2006) Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition. Toxicol. Appl. Pharmacol. 214, 109-117
    • (2006) Toxicol. Appl. Pharmacol. , vol.214 , pp. 109-117
    • Ishihara, Y.1    Shiba, D.2    Shimamoto, N.3
  • 34
    • 79956187997 scopus 로고    scopus 로고
    • Increased expression of c-Fos by extracellular signal-regulated kinase activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis
    • Ishihara, Y., Ito, F., and Shimamoto, N. (2011) Increased expression of c-Fos by extracellular signal-regulated kinase activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis. FEBS J. 278, 1873-1881
    • (2011) FEBS J. , vol.278 , pp. 1873-1881
    • Ishihara, Y.1    Ito, F.2    Shimamoto, N.3
  • 35
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai, T., and Akira, S. (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11, 373-384
    • (2010) Nat. Immunol. , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 36
    • 85047677305 scopus 로고    scopus 로고
    • Nuclear factor κB-dependent mechanisms coordinate the synergistic effect of PMA and cytokines on the induction of superoxide dismutase 2
    • Kiningham, K. K., Xu, Y., Daosukho, C., Popova, B., and St Clair, D. K. (2001) Nuclear factor κB-dependent mechanisms coordinate the synergistic effect of PMA and cytokines on the induction of superoxide dismutase 2. Biochem. J. 353, 147-156
    • (2001) Biochem. J. , vol.353 , pp. 147-156
    • Kiningham, K.K.1    Xu, Y.2    Daosukho, C.3    Popova, B.4    St Clair, D.K.5
  • 37
    • 0032588841 scopus 로고    scopus 로고
    • An intronic NF-κB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-α and interleukin-1β
    • Xu, Y., Kiningham, K. K., Devalaraja, M. N., Yeh, C. C., Majima, H., Kasarskis, E. J., and St Clair, D. K. (1999) An intronic NF-κB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-α and interleukin-1β. DNA Cell Biol. 18, 709-722
    • (1999) DNA Cell Biol. , vol.18 , pp. 709-722
    • Xu, Y.1    Kiningham, K.K.2    Devalaraja, M.N.3    Yeh, C.C.4    Majima, H.5    Kasarskis, E.J.6    St Clair, D.K.7
  • 38
    • 35348960414 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-κB activation
    • Kairisalo, M., Korhonen, L., Blomgren, K., and Lindholm, D. (2007) X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-κB activation. Biochem. Biophys. Res. Commun. 364, 138-144
    • (2007) Biochem. Biophys. Res. Commun. , vol.364 , pp. 138-144
    • Kairisalo, M.1    Korhonen, L.2    Blomgren, K.3    Lindholm, D.4
  • 40
    • 0031574131 scopus 로고    scopus 로고
    • NF kappa B-independent transcriptional induction of the human manganous superoxide dismutase gene
    • Borrello, S., and Demple, B. (1997) NF kappa B-independent transcriptional induction of the human manganous superoxide dismutase gene. Arch. Biochem. Biophys. 348, 289-294
    • (1997) Arch. Biochem. Biophys. , vol.348 , pp. 289-294
    • Borrello, S.1    Demple, B.2
  • 41
    • 16644379342 scopus 로고    scopus 로고
    • Manganese superoxide dismutase is induced by endoplasmic reticulum stress through IRE1-mediated nuclear factor (NF)-κB and AP-1 activation
    • Kaneko, M., Takahashi, T., Niinuma, Y., and Nomura, Y. (2004) Manganese superoxide dismutase is induced by endoplasmic reticulum stress through IRE1-mediated nuclear factor (NF)-κB and AP-1 activation. Biol. Pharm. Bull. 27, 1202-1206
    • (2004) Biol. Pharm. Bull. , vol.27 , pp. 1202-1206
    • Kaneko, M.1    Takahashi, T.2    Niinuma, Y.3    Nomura, Y.4
  • 42
    • 28644441753 scopus 로고    scopus 로고
    • Redox regulation of manganese superoxide dismutase
    • Warner, B. B., Stuart, L., Gebb, S., and Wispé, J. R. (1996) Redox regulation of manganese superoxide dismutase. Am. J. Physiol. 271, L150-L158
    • (1996) Am. J. Physiol. , vol.271 , pp. L150-L158
    • Warner, B.B.1    Stuart, L.2    Gebb, S.3    Wispé, J.R.4
  • 43
    • 0028829574 scopus 로고
    • Activation of NF-κB and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells
    • Das, K. C., Lewis-Molock, Y., and White, C. W. (1995) Activation of NF-κB and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells. Am. J. Physiol. 269, L588-L602
    • (1995) Am. J. Physiol. , vol.269 , pp. L588-L602
    • Das, K.C.1    Lewis-Molock, Y.2    White, C.W.3
  • 44
    • 14044279966 scopus 로고    scopus 로고
    • Toll-like receptor 4 on nonhematopoieticcellssustainsCNSinflammationduringendotoxemia, independent of systemic cytokines
    • Chakravarty, S., and Herkenham, M. (2005) Toll-like receptor 4 on nonhematopoieticcellssustainsCNSinflammationduringendotoxemia, independent of systemic cytokines. J. Neurosci. 25, 1788-1796
    • (2005) J. Neurosci. , vol.25 , pp. 1788-1796
    • Chakravarty, S.1    Herkenham, M.2
  • 46
    • 84903649897 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release
    • Zorov, D. B., Juhaszova, M., and Sollott, S. J. (2014) Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiol. Rev. 94, 909-950
    • (2014) Physiol. Rev. , vol.94 , pp. 909-950
    • Zorov, D.B.1    Juhaszova, M.2    Sollott, S.J.3
  • 49
    • 84877662957 scopus 로고    scopus 로고
    • Oxidative stress induces inactivation of protein phosphatase 2A, promoting proinflammatory NF-κB in aged rat kidney
    • Jin Jung, K., Hyun Kim, D., Kyeong Lee, E., Woo Song, C., Pal Yu, B., and Young Chung, H. (2013) Oxidative stress induces inactivation of protein phosphatase 2A, promoting proinflammatory NF-κB in aged rat kidney. Free Radic. Biol. Med. 61, 206-217
    • (2013) Free Radic. Biol. Med. , vol.61 , pp. 206-217
    • Jin Jung, K.1    Hyun Kim, D.2    Kyeong Lee, E.3    Woo Song, C.4    Pal Yu, B.5    Young Chung, H.6
  • 51
    • 35748948033 scopus 로고    scopus 로고
    • A polymorphism in SOD2 is associated with development of Alzheimer's disease
    • Wiener, H. W., Perry, R. T., Chen, Z., Harrell, L. E., and Go, R. C. (2007) A polymorphism in SOD2 is associated with development of Alzheimer's disease. Genes Brain Behav. 6, 770-775
    • (2007) Genes Brain Behav. , vol.6 , pp. 770-775
    • Wiener, H.W.1    Perry, R.T.2    Chen, Z.3    Harrell, L.E.4    Go, R.C.5
  • 52
    • 77954315710 scopus 로고    scopus 로고
    • Val-9Ala and Ile 58Thr polymorphism of MnSOD in Parkinson's disease
    • Wang, V., Chen, S. Y., Chuang, T. C., Shan, D. E., Soong, B. W., and Kao, M. C. (2010) Val-9Ala and Ile 58Thr polymorphism of MnSOD in Parkinson's disease. Clin. Biochem. 43, 979-982
    • (2010) Clin. Biochem. , vol.43 , pp. 979-982
    • Wang, V.1    Chen, S.Y.2    Chuang, T.C.3    Shan, D.E.4    Soong, B.W.5    Kao, M.C.6
  • 53
    • 0030582372 scopus 로고    scopus 로고
    • Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene: A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease
    • Shimoda-Matsubayashi, S., Matsumine, H., Kobayashi, T., Nakagawa-Hattori, Y., Shimizu, Y., and Mizuno, Y. (1996) Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene: a predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease. Biochem. Biophys. Res. Commun. 226, 561-565
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , pp. 561-565
    • Shimoda-Matsubayashi, S.1    Matsumine, H.2    Kobayashi, T.3    Nakagawa-Hattori, Y.4    Shimizu, Y.5    Mizuno, Y.6
  • 55
    • 77955418350 scopus 로고    scopus 로고
    • Analysis of two polymorphisms of the manganese superoxide dismutase gene (Ile-58Thr and Ala-9Val) in patients with recurrent depressive disorder
    • Gałecki, P., Smigielski, J., Florkowski, A., Bobińska, K., Pietras, T., and Szemraj, J. (2010) Analysis of two polymorphisms of the manganese superoxide dismutase gene (Ile-58Thr and Ala-9Val) in patients with recurrent depressive disorder. Psychiatry Res. 179, 43-46
    • (2010) Psychiatry Res. , vol.179 , pp. 43-46
    • Gałecki, P.1    Smigielski, J.2    Florkowski, A.3    Bobińska, K.4    Pietras, T.5    Szemraj, J.6


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