Increased expression of c-Fos by extracellular signal-regulated kinase activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis

FEBS Journal

Volumn 278, Issue 11, 2011, Pages 1873-1881

  Ishihara, Yasuhiro ^a   Ito, Fumiaki ^b   Shimamoto, Norio ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b SETSUNAN UNIVERSITY   (Japan)

Author keywords

apoptosis; Bim; c Fos; extracellular signal regulated kinase (ERK); reactive oxygen species

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; AMITROLE; ASCORBIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C FOS; PROTEIN C JUN; THIOMALIC ACID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR BIMEL; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE LOCATION; GENE MUTATION; GENE REPRESSION; GENE VECTOR; LIVER CELL; MALE; MOLECULAR CLONING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; DNA PRIMERS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEPATOCYTES; MUTAGENESIS, SITE-DIRECTED; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RNA INTERFERENCE; UP-REGULATION;

RATTUS;

EID: 79956187997     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08105.x     Document Type: Article

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