Oxidative stress induces inactivation of protein phosphatase 2A, promoting proinflammatory NF-κB in aged rat kidney

Free Radical Biology and Medicine

Volumn 61, Issue , 2013, Pages 206-217

  Jung, Kyung Jin ^a,b   Kim, Dae Hyun ^b   Lee, Eun Kyeong ^b,c   Song, Chang Woo ^a   Yu, Byung Pal ^b,d   Chung, Hae Young ^b  

^a Korea Institute of Toxicology   (South Korea)

^b Pusan National University   (South Korea)

^c Korea Institute of Radiation and Medical Science   (South Korea)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Aging; Free radicals; Molecular inflammation; NF B; Oxidative stress; PP2A

Indexed keywords

2,2 AZOBIS( 2 AMIDINO PROPANE); 3 (4 TERT BUTYLPHENYLSULFONYL) 2 PROPENENITRILE; ACETYLCYSTEINE; CALYCULIN A; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; SMALL INTERFERING RNA; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG; VANADATE SODIUM;

AGED; AGING; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CALORIC RESTRICTION; CATALYSIS; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; FOOD INTAKE; HUMAN; HUMAN CELL; KIDNEY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR UPREGULATION;

MUS; RATTUS;

EID: 84877662957     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.04.005     Document Type: Article

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