Regulation of oxidative stress in long-lived lipopolysaccharide-activated microglia

Clinical and Experimental Pharmacology and Physiology

Volumn 39, Issue 7, 2012, Pages 599-607

  Kaneko, Yoko S ^a   Ota, Akira ^a   Nakashima, Akira ^a   Mori, Keiji ^a,b   Nagatsu, Ikuko ^a   Nagatsu, Toshiharu ^a,c  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KINJO UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

Lipopolysaccharide; Microglia; Superoxide dismutase; Toll like receptor 4

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; MICROGLIA; MOUSE; NERVE DEGENERATION; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN EXPRESSION;

ANIMALS; CATALASE; CELL SEPARATION; FREE RADICALS; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C3H; MICROGLIA; NEURODEGENERATIVE DISEASES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TOLL-LIKE RECEPTOR 4;

EID: 84862895328     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2012.05716.x     Document Type: Article

References (27)

1. Aloisi F. Immune function of microglia. Glia 2001; 36: 165-79.
2. Nagatsu T, Sawada M. Cellular and molecular mechanisms of Parkinson's disease: Neurotoxins, causative genes, and inflammatory cytokines. Cell. Mol. Neurobiol. 2006; 26: 781-802.
3. Lee JA, Song HY, Ju SM et al. Suppression of inducible nitric oxide synthase and cyclooxygenase-2 by cell-permeable superoxide dismutase in lipopolysaccharide-stimulated BV-2 microglial cells. Mol. Cell 2010; 29: 245-50.
4. McGeer PL, Yasojima K, McGeer EC. Inflammation in Parkinson's disease. Adv. Neurol. 2001; 86: 83-9.
5. Block ML, Hong JS. Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism. Prog. Neurobiol. 2005; 76: 77-98.
6. Lee P, Lee J, Kim S et al. NO as an autocrine mediator in the apoptosis of activated microglial cells: Correlation between activation and apoptosis of microglial cells. Brain Res. 2001; 892: 380-5.
7. Liu BL, Hong JS. Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide. J. Pharmacol. Exp. Ther. 2000; 293: 607-17.
8. Gao HM, Jiang J, Wilson B, Zhang W, Hong JS, Liu B. Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: Relevance to Parkinson's disease. J. Neurochem. 2002; 81: 1285-97.
9. Gonzalez-Zulueta M, Ensz LM, Mukhina G et al. Manganese superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity. J. Neurosci. 1998; 18: 2040-55.
10. Kaneko YS, Mori K, Nakashima A, Sawada M, Nagatsu I, Ota A. Peripheral injection of lipopolysaccharide enhances expression of inflammatory cytokines in murine locus coeruleus: Possible role of increased norepinephrine turnover. J. Neurochem. 2005; 94: 393-404.
11. Kaneko YS, Nakashima A, Mori K, Nagatsu T, Nagatsu I, Ota A. Lipopolysaccharide extends the lifespan of mouse primary-cultured microglia. Brain Res. 2009; 1279: 9-20.
12. Cho BP, Song DY, Sugama S et al. Pathological dynamics of activated microglia following medial forebrain bundle transection. Glia 2006; 53: 92-102.
13. Hwang KY, Oh YT, Yoon H et al. Baicalein suppresses hypoxia-induced HIF-1α protein accumulation and activation through inhibition of reactive oxygen species and PI 3-kinase/Akt pathway in BV2 murine microglial cells. Neurosci. Lett. 2008; 444: 264-9.
14. Poltorak A, He X, Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 1998; 282: 2085-8.
15. Qureshi ST, Larivière L, Leveque G et al. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 1999; 189: 615-25.
16. Oh YT, Lee JY, Lee J et al. Oleic acid reduces lipopolysaccharide-induced expression of iNOS and COX-2 in BV2 murine microglial cells: Possible involvement of reactive oxygen species, p38 MAPK, and IKK/NF-κB signaling pathways. Neurosci. Lett. 2009; 464: 93-7.
17. Almeida A, Cidad P, Delgado-Esteban M, Fernández E, García-Nogales P, Bolaños JP. Inhibition of mitochondrial respiration by nitric oxide: Its role in glucose metabolism and neuroprotection. J. Neurosci. Res. 2005; 79: 166-71.
18. Sugaya K, Chouinard ML, McKinney M. Induction of manganese superoxide dismutase in BV-2 microglial cells. NeuroReport 1997; 8: 3547-51.
19. Horvath TL, Andrews ZB, Diano S. Fuel utilization by hypothalamic neurons: Roles for ROS. Trends Endocrinol. Metab. 2009; 20: 78-87.
20. Speranza L, Franceschelli S, Pesce M et al. Antiinflammatory effects in THP-1 cells treated with verbascoside. Phytother. Res. 2010; 24: 1398-404.
21. Aly HA, Lightfoot DA, El-Shemy HA. Bacterial lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro. Toxicol. In Vitro 2010; 24: 1266-72.
22. Lehnardt SL, Massillon L, Follet P et al. Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway. Proc. Natl Acad. Sci. USA 2003; 100: 8514-9.
23. Qin L, Li G, Qian X et al. Interactive role of the Toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation. Glia 2005; 52: 78-84.
24. Chang SC, Kao MC, Fu MT, Lin CT. Modulation of NO and cytokines in microglial cells by Cu/Zn-superoxide dismutase. Free Radic. Biol. Med. 2001; 31: 1084-9.
25. Bordet R, Deplanque D, Maboudou P et al. Increase in endogenous brain superoxide dismutase as a potential mechanism of lipopolysaccharide-induced brain ischemic tolerance. J. Cereb. Blood Flow Metab. 2000; 20: 1190-6.
26. Hinerfeld D, Traini MD, Weinberger RP et al. Endogenous mitochondrial oxidative stress: Neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice. J. Neurochem. 2004; 88: 657-67.
27. Esposito L, Raber J, Kekonius L et al. Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. J. Neurosci. 2006; 26:5167-79.