Brca2 deficiency leads to T cell loss and immune dysfunction

Molecules and Cells

Volumn 38, Issue 3, 2015, Pages 251-258

  Jeong, Jun Hyeon ^c   Jo, Areum ^a,b   Park, Pilgu ^c   Lee, Hyunsook ^c   Lee, Hae Ock ^a,b  

^a Samsung Medical Center   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Breast cancer type 2 susceptibility gene (BRCA2); Knockout mouse; T cell

Indexed keywords

BRCA2 PROTEIN; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN M; INTERLEUKIN 4; PROTEIN P53; T LYMPHOCYTE RECEPTOR; BRCA2 PROTEIN, MOUSE;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRTH; CELL COUNT; CELL LOSS; CELL POPULATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE MUTATION; HAPLOINSUFFICIENCY; HETEROZYGOTE; IMMUNE DEFICIENCY; IMMUNE RESPONSE; KNOCKOUT MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE; THYMUS LYMPHOMA; ANIMAL; CELLULAR IMMUNITY; DEFICIENCY; FANCONI ANEMIA; GENETICS; IMMUNOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; SPLEEN; THYMUS; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; BRCA2 PROTEIN; FANCONI ANEMIA; IMMUNITY, CELLULAR; MICE, TRANSGENIC; SPLEEN; T-LYMPHOCYTES; THYMUS GLAND; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84941296540     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.14348/molcells.2015.2302     Document Type: Article

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