Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues

Developmental Biology

Volumn 184, Issue 2, 1997, Pages 385-401

  Rajan, Jayant V ^a   Marquis, Sandra T ^a   Gardner, Heather Perry ^a   Chodosh, Lewis A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; MESSENGER RNA; PROGESTERONE; SEX HORMONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; FETUS DEVELOPMENT; GENE EXPRESSION REGULATION; MALE; MOUSE; NONHUMAN; OVARIECTOMY; PHENOTYPE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; TISSUE INDUCTION; TUMOR SUPPRESSOR GENE;

ANIMALIA; MURINAE;

EID: 0031569873     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1997.8526     Document Type: Article

References (54)

1. Boice J. D. Jr., Monson R. R. Breast cancer in women after repeated fluoroscopic examinations of the chest. J. Natl. Cancer Inst. 59:1977;823-832.
2. Buhler T. A., Dale T. C., Kieback C., Humphreys R. C., Rosen J. M. Localization and quantification of Wnt-2 gene expression in mouse mammary development. Dev. Biol. 155:1993;87-96.
3. Chen Y., Farmer A., Chen C.-F., Jones D., Chen P.-L., Lee W.-H. BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner. Cancer Res. 56:1996;3168-3172.
4. Chirgwin J. M., Przybyla A. E., MacDonald R. J., Rutter W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
5. Claus E. B., Risch N., Thompson W. D. Genetic analysis of breast cancer in the cancer and steroid hormone study. Am. J. Hum. Genet. 48:1991;232-241.
6. Colditz G. A., Rosner B. A., Speizer F. E. Risk factors for breast cancer according to family history of breast cancer. J. Natl. Cancer Inst. 88:1996;365-371.
7. Collins N., McManus R., Wooster R., Mangion J., Seal S., Lakhani S. R. Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13. Oncogene. 10:1995;1673-1675.
8. Couch F. J., Rommens J., Neuhausen S., Belanger C., Dumont M., Abel K. Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13. Genomics. 36:1996a;86-99.
9. Couch F. J., Farid L. M., DeShano M. L., Tavtigian S. V., Calzone K., Campeau L. BRCA2 germline mutations in male breast cancer cases and breast cancer families. Nature Genet. 13:1996b;123-125.
10. Crichlow R. W. Carcinoma of the male breast. Surg. Gynecol. Obstet. 134:1972;1011-1019.
11. Easton D. F., Bishop D. T., Ford D., Crockford G. P. The Breast Cancer Linkage consortium. Genetic linkage analysis in familial breast and ovarian cancer. Results from 214 families. Am. J. Hum. Genet. 52:1993;678-701.
12. Gavin B. J., McMahon A. P. Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland. Mol. Cell. Biol. 12:1992;2418-2423.
13. Gowen L. C., Johnson B. L., Latour A. M., Sulik K. K., Koller B. Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities. Nature Genet. 12:1996;191-194.
14. Gudas J., Li T., Nguyen H., Jensen D., Rauscher F. I., Cowan K. Cell cycle regulation of BRCA1 messenger RNA in human breast epithelial cells. Cell Growth Differ. 7:1996;717-723.
15. Gudmundsson J., Johannesdottir G., Bergthorsson J. T., Arason A., Ingvarsson S., Egilsson V. Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12q13. Cancer Res. 55:1995;4830-4832.
16. Hakem R., de la Pompa J., Sirard C., Mo R., Woo M., Hakem A. The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. Cell. 85:1996;1009-1024.
17. Hall J., Lee M., Newman B., Morrow J., Anderson L., Huey B., King M.-C. Linkage of early-onset familial breast cancer to chromosome 17q21. Science. 250:1990;1684-1689.
18. Holt J., Thompson M., Szabo C., Robinson-Benion C., Arteaga C., King M.-C., Jensen R. Growth retardation and tumour inhibition by BRCA1. Nature Genet. 12:1996;298-302.
19. Janca F. C., Jost L. K., Evenson D. P. Mouse testicular and sperm cell development characterized from birth to adulthood by dual parameter flow cytometry. Biol. Reprod. 34:1986;613-623.
20. Knudson A. G. Antioncogenes and human cancer. Proc. Natl. Acad. Sci. USA. 90:1993;10914-10921.
21. Lambe M., Hsieh C.-C., Tricholpoulos D., Ekbom A., Pavia M., Adami H.-O. Transient increase in the risk of breast cancer after giving birth. N. Engl. J. Med. 331:1994;5-9.
22. Lancaster J. M., Wooster R., Mangion J., Phelan C. M., Cochran C., Gumbs C. BRCA2 mutations in primary breast and ovarian cancers. Nature Genet. 13:1996;238-240.
23. Lane T. F., Deng C. X., Elson A., Lyu M. S., Kozak C. A., Leder P. Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice. Genes Dev. 9:1995;2712-2722.
24. Liu C.-Y., Flesken-Nikitin A., Li S., Zeng Y., Lee W.-H. Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development. Genes Dev. 10:1996;1835-1843.
25. MacMahon B., Cole P., Lin T. M., Lowe C. R., Mirra A. P., Ravnihar B. Age at first birth and breast cancer risk. Bull. WHO. 43:1970;209-221.
26. Marquis S. T., Rajan J. V., Wynshaw-Boris A., Xu J., Yin G.-Y., Abel K. J., Weber B. L., Chodosh L. A. The developmental pattern ofBrca1. Nature Genet. 11:1995;17-26.
27. McGregor H., Land C. E., Choi K., Tokuoka S., Liu P. I., Wakabayashi T., Beebe G. W. Breast cancer incidence among atomic bomb survivors, Hiroshima and Nagasaki, 1950-69. J. Natl. Cancer Inst. 59:1977;799-811.
28. Meyskens F. L. J., Tormey D. C., Neifeld J. P. Male breast cancer: A review. Cancer Treat. Rev. 3:1976;83-93.
29. Miki Y., Katagiri T., Kasumi F., Yoshimoto T., Nakamura Y. Mutation analysis in the BRCA2 gene in primary breast cancers. Nature Genet. 13:1996;245-247.
30. Miki Y., Swensen J., Shattuck-Eidens D., Futreal P. A., Harshman K., Tavtigian S. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science. 266:1994;66-71.
31. Nebel B. R., Amarose A. P., Hackett E. M. Calendar of gametogenic development in the prepubertal male mouse. Science. 134:1961;832-833.
32. Neuhausen S., Gilewski T., Norton L., Tran T., McGuire P., Swensen J. Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer. Nature Genet. 13:1996;126-128.
33. Newman B., Austin M. A., Lee M., King M.-C. Inheritance of breast cancer: evidence for autosomal dominant transmission in high risk families. Proc. Natl. Acad. Sci. USA. 85:1988;1-5.
34. Parker S. B., Eichele G., Zhang P., Rawls A., Sands A. T., Bradley A. p53-independent expression of p21/CIP1 in muscle and other terminally differentiating cells. Science. 267:1995;1024-1027.
35. Phelan C. M., Lancaster J. M., Tonin P., Grumbs C., Cochran C., Carter R. Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families. Nature Genet. 13:1996;120-122.
36. Rajan J. V., Wang M., Marquis S. T., Chodosh L. A. Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells. Proc. Natl. Acad. Sci. USA. 93:1996;13078-13083.
37. Rao V. N., Shao N. S., Ahmad M., Reddy R. S. P. Antisense RNA to the putative tumor suppressor gene BRCA1 transforms mouse fibroblasts. Oncogene. 12:1996;523-528.
38. Russo J., Rivera R., Russo I. H. Influence of age and parity on the development of the human breast. Breast Cancer Res. Treat. 23:1992;211-218.
39. Russo J., Russo I. H. Development pattern of human breast and susceptibility to carcinogenesis. Eur. J. Cancer Prevent. 2:1993.
40. Russo J., Tay L. K., Russo I. H. Differentiation of the mammary gland and susceptibility to carcinogenesis. Breast Cancer Res. Treat. 2:1982;5-73.
41. Smith S. A., Easton D. G., Evans D. G. R., Ponder B. A. J. Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome. Nature Genet. 2:1992;128-131.
42. Stratton M. R., Ford D., Neuhasen S., Seal S., Wooster R., Friedman L. S. Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q. Nature Genet. 7:1994;103-107.
43. Tavtigian S. V., Simard J., Rommens J., Couch F., Sharluck-Eidens D., Neuhausen S. The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. Nature Genet. 12:1996;333-337.
44. Teng D. H.-F., Bogden R., Mitchell J., Baumgard M., Bell R., Berry S. Low incidence of BRCA2 mutations in breast carcinoma and other cancers. Nature Genet. 13:1996;241-244.
45. Thomas D. B., Jimenez L. M., McTiernan A., Rosenblatt K., Stalsberg H., Stemhagen A. Breast cancer in men: Risk factors with hormonal implications. Am. J. Epidemiol. 135:1992;734-748.
46. Thompson M. E., Jensen R. A., Obermiller P. S., Page D. L., Holt J. T. Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nature Genet. 9:1995;444-450.
47. Thorlacius S., Olafsdottir G., Tryggvadottir L., Neuhausen S., Jonasson J. G., Tavtigian S. V. A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes. Nature Genet. 13:1996;117-119.
48. Thorlacius S., Tryggvodorttir L., Olafsdottir G. H., Jonasson J. G., Ogmundsdottir H. M., Tulinius H. Linkage to BRCA1 region in hereditary male breast cancer. Lancet. 346:1995;544-545.
49. van Leeuwen F. E., Klokman W. J., Hagenbeck A., Noyon R., van den Belt-Dusebout A. W., van Kerkhoff E. H. Second cancer risk following Hodgkin's Disease: A 20-year follow-up study. J. Clin. Oncol. 12:1994;312-325.
50. Vaughn J., Cirisano F., Huper G., Berchuck A., Futreal P., Marks J., Iglehart J. Cell cycle control of BRCA2. Cancer Res. 56:1996a;4590-4594.
51. Vaughn J., Davis P., Jarboe M., Huper G., Evans A., Wiseman R. BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells. Cell Growth Differ. 7:1996b;711-715.
52. Wooster R., Bignell G., Lancaster J., Swift S., Seal S., Mangion J. Identification of the breast cancer susceptibility gene BRCA2. Nature. 378:1995;789-792.
53. Wooster R., Mangion J., Eeles R., Smith S., Dowsett M., Averill D. A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome. Nature Genet. 2:1992;132-134.
54. Wooster R., Neuhausen S. L., Mangion J., Quirk Y., Ford D., Collins N. Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science. 265:1994;2088-2090.