Risk of cancer other than breast or ovarian in individuals with BRCA1 and BRCA2 mutations

Familial Cancer

Volumn 11, Issue 2, 2012, Pages 235-242

  Moran, A ^a   O'Hara, C ^a   Khan, S ^a   Shack, L ^b   Woodward, E ^c,d   Maher, E R ^c,d   Lalloo, F ^e   Evans, D G R ^e  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^d BIRMINGHAM WOMEN S HOSPITAL   (United Kingdom)

^e ST MARY S HOSPITAL   (United Kingdom)

Author keywords

BRCA1; BRCA2; Oesophageal cancer; Pancreatic cancer; Prostate cancer; Uveal melanoma

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADOLESCENT; ADULT; AGED; ARTICLE; BILE DUCT CANCER; BLADDER CANCER; BRAIN CANCER; BREAST CANCER; BRONCHUS CANCER; CANCER RISK; COLORECTAL CANCER; CUTANEOUS MELANOMA; ESOPHAGUS CANCER; FAMILY STUDY; FEMALE; GALLBLADDER CANCER; GENE MUTATION; HEMATOLOGIC MALIGNANCY; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MELANOMA; OVARY CANCER; PANCREAS CANCER; PRIORITY JOURNAL; PROSTATE CANCER; RISK ASSESSMENT; STOMACH CANCER; TRACHEA CANCER; UTERUS CANCER; UVEA MELANOMA;

ADOLESCENT; ADULT; AGED; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MELANOMA; MIDDLE AGED; MUTATION; NEOPLASMS; OVARIAN NEOPLASMS; PANCREATIC NEOPLASMS; PEDIGREE; PROSTATIC NEOPLASMS; RISK FACTORS; UVEAL NEOPLASMS; YOUNG ADULT;

EID: 84864360055     PISSN: 13899600     EISSN: 15737292     Source Type: Journal    
DOI: 10.1007/s10689-011-9506-2     Document Type: Article

References (27)

1. Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S et al (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266(5182): 66-71
2. Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J et al (1995) Identification of the breast cancer susceptibility gene BRCA2. Nature 378(6559):789-792
3. Ford D, Easton DF, Stratton M, Narod S, Goldgar D, Devilee P et al (1998) Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The breast cancer linkage consortium. Am J Hum Genet 62(3):676-689
4. Struewing JP, Hartge P, Wacholder S, Baker SM, Berlin M, McAdams M et al (1997) The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N Engl J Med 336(20):1401-1408
5. Warner E, Foulkes W, Goodwin P, Meschino W, Blondal J, Paterson C et al (1999) Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer. J Natl Cancer Inst 91(14):1241-1247
6. Hopper JL, Southey MC, Dite GS, Jolley DJ, Giles GG, McCredie MR et al (1999) Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein-Truncating mutations in BRCA1 and BRCA2. Australian breast cancer family study. Cancer Epidemiol Biomarkers Prev 8(9):741-747
7. Antoniou A, Pharoah PDP, Narod S, Risch HA, Eyfjord JE, Hopper J, Loman N, Olsson H, Johannsson O, Borg A, Pasini B, Radice P, Manoukian S, Eccles D, Tang N, Olah E, Anton-Culver H, Warner E, Lubinski J, Gronwald J, Gorski B, Tulinius H, Thorlacius S, Eerola H, Nevanlinna H, Syrjakoski K, Kallionemi O-P, Thompson D, Evans C, Peto J, Lalloo F, Evans DG, Easton DF (2005) Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: A combined analysis of 22 population based studies. J Med Genet 42(7):602-603
8. Chen S, Iversen ES, Friebel T, Finkelstein D, Weber BL, Eisen A, Peterson LE, Schildkraut JM, Isaacs C, Peshkin BN, Corio C, Leondaridis L, Tomlinson G, Dutson D, Kerber R, Amos CI, Strong LC, Berry DA, Euhus DM, Parmigiani G (2006) Characterization of BRCA1 and BRCA2 mutations in a large United States sample. J Clin Oncol 24(6):863-871
9. King MC, Marks JH, Mandell JB (2003) Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science 302(5645):643-646
10. Evans DG, Shenton A, Woodward E, Lalloo F, Howell A, Maher ER (2008) Penetrance estimates for BRCA1 and BRCA2 based on genetic testing in a clinical cancer genetics service setting. BMC Cancer 8(1):155
11. Easton DF, Steele L, Fields P, Ormiston W, Averill D, Daly PA et al (1997) Cancer risks in two large breast cancer families linked to BRCA2 on chromosome 13q12-13. Am J Hum Genet 61(1):120-128
12. The breast cancer linkage consortium (1999) Cancer risks in BRCA2 mutation carriers. The breast cancer linkage consortium. J Natl Cancer Inst 91(15):1310-1316
13. Thompson D, Easton DF (2002) Breast cancer linkage consortium. Cancer incidence in BRCA1 mutation carriers. J Natl Cancer Inst 94(18):1358-1365
14. Ford D, Easton DF, Bishop DT, Narod SA, Goldgar DE (1994) Risks of cancer in BRCA1-mutation carriers. Breast cancer linkage consortium. Lancet 343(8899):692-695
15. van Asperen CJ, Brohet RM, Meijers-Heijboer EJ, Hoogerbrugge N, Verhoef S, Vasen HF, Ausems MG, Menko FH, Gomez Garcia EB, Klijn JG, Hogervorst FB, van Houwelingen JC, van't Veer LJ, Rookus MA, van Leeuwen FE (2005) Netherlands collaborative group on hereditary breast cancer (HEBON). Cancer risks in BRCA2 families: Estimates for sites other than breast and ovary. J Med Genet 42(9):711-719
16. Gruber SB, Petersen GM (2002) Cancer risks in BRCA1 carriers: Time for the next generation of studies. J Natl Cancer Inst 94(18):1344-1345
17. Breslow NE, Day NE (1987) Statistical methods in cancer research vol II. the design and analysis of cohort studies (IARC Scientific Publication No 82). International Agency for Research on Cancer, Lyon.
18. Liede A, Karlan BY, Narod SA (2004) Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: A review of the literature. J Clin Oncol 22(4):735-742
19. Dite GS, Whittemore AS, Knight JA, John EM, Milne RL, Andrulis IL, Southey MC, McCredie MR, Giles GG, Miron A, Phipps AI, West DW, Hopper JL (2010) Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutations. Br J Cancer 103(7): 1103-1108
20. Cybulski C, Górski B, Gronwald J, Huzarski T, Byrski T, Debniak T, Jakubowska A, Wokolorczyk D, Gliniewicz B, Sikorski A, Stawicka M, Godlewski D, Kwias Z, Antczak A, Krajka K, Lauer W, Sosnowski M, Sikorska-Radek P, Bar K, Klijer R, Romuald Z, Malkiewicz B, Borkowski A, Borkowski T, Szwiec M, Posmyk M, Narod SA, Lubiński J (2008) BRCA1 mutations and prostate cancer in Poland. Eur J Cancer Prev 17(1):62-66
21. Lawniczak M, Gawin A, Bialek A, Lubiński J, Starzyńska T (2008) Is there any relationship between BRCA1 gene mutation and pancreatic cancer development? Pol Arch Med Wewn 118(11):645-649
22. Ferrone CR, Levine DA, Tang LH, Allen PJ, Jarnagin W, Brennan MF, Offit K, Robson ME (2009) BRCA germline mutations in Jewish patients with pancreatic adenocarcinoma. J Clin Oncol 27(3):433-438
23. Niell BL, Rennert G, Bonner JD, Almog R, Tomsho LP, Gruber SB (2004) BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer. J Natl Cancer Inst 96(1):15-21
24. Hearle N, Damato BE, Humphreys J, Wixey J, Green H, Stone J, Easton DF, Houlston RS (2003) Contribution of germline mutations in BRCA2, P16(INK4A), P14(ARF) and P15 to uveal melanoma. Invest Ophthalmol Vis Sci 44(2):458-462
25. Ginsburg OM, Kim-Sing C, Foulkes WD, Ghadirian P, Lynch HT, Sun P, Narod SA (2010) Hereditary breast cancer clinical study group. BRCA1 and BRCA2 families and the risk of skin cancer. Fam Cancer [Epub ahead of print]
26. Douglas FS, O'Dair LCO, Robinson M, Evans DGR, Lynch SA (1999) The accuracy of diagnosis as reported by the proband in families with cancer: A retrospective study. J Med Genet 36: 309-312
27. Akbari MR, Malekzadeh R, Nasrollahzadeh D, Amanian D, Islami F, Li S, Zandvakili I, Shakeri R, Sotoudeh M, Aghcheli K, Salahi R, Pourshams A, Semnani S, Boffetta P, Dawsey SM, Ghadirian P, Narod SA (2008) Germline BRCA2 mutations and the risk of esophageal squamous cell carcinoma. Oncogene 27(9):1290-1296