메뉴 건너뛰기




Volumn 91, Issue , 2015, Pages 52-69

Delivery strategies to enhance oral vaccination against enteric infections

Author keywords

Adjuvant; Delivery system; Gastrointestinal; Mucosal; Nanoparticle; Oral; Vaccine

Indexed keywords

ANTIGENS; DISEASES; NANOPARTICLES; SALMONELLA;

EID: 84940953399     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2015.03.007     Document Type: Review
Times cited : (127)

References (259)
  • 2
    • 84861926839 scopus 로고    scopus 로고
    • W.H.O. Child Health Epidemiology Reference Group of, Unicef, Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000
    • Liu L., Johnson H.L., Cousens S., Perin J., Scott S., Lawn J.E., Rudan I., Campbell H., Cibulskis R., Li M., Mathers C., Black R.E. W.H.O. Child Health Epidemiology Reference Group of, Unicef, Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet 2012, 379:2151-2161.
    • (2012) Lancet , vol.379 , pp. 2151-2161
    • Liu, L.1    Johnson, H.L.2    Cousens, S.3    Perin, J.4    Scott, S.5    Lawn, J.E.6    Rudan, I.7    Campbell, H.8    Cibulskis, R.9    Li, M.10    Mathers, C.11    Black, R.E.12
  • 5
    • 79952929452 scopus 로고    scopus 로고
    • From cholera to enterotoxigenic Escherichia coli (ETEC) vaccine development
    • Svennerholm A.M. From cholera to enterotoxigenic Escherichia coli (ETEC) vaccine development. Indian J. Med. Res. 2011, 133:188-196.
    • (2011) Indian J. Med. Res. , vol.133 , pp. 188-196
    • Svennerholm, A.M.1
  • 6
    • 84862278742 scopus 로고    scopus 로고
    • Strategies to overexpress enterotoxigenic Escherichia coli (ETEC) colonization factors for the construction of oral whole-cell inactivated ETEC vaccine candidates
    • Tobias J., Svennerholm A.M. Strategies to overexpress enterotoxigenic Escherichia coli (ETEC) colonization factors for the construction of oral whole-cell inactivated ETEC vaccine candidates. Appl. Microbiol. Biotechnol. 2012, 93:2291-2300.
    • (2012) Appl. Microbiol. Biotechnol. , vol.93 , pp. 2291-2300
    • Tobias, J.1    Svennerholm, A.M.2
  • 9
    • 80052015820 scopus 로고    scopus 로고
    • Live attenuated influenza vaccine (FluMist(R); Fluenz): a review of its use in the prevention of seasonal influenza in children and adults
    • Carter N.J., Curran M.P. Live attenuated influenza vaccine (FluMist(R); Fluenz): a review of its use in the prevention of seasonal influenza in children and adults. Drugs 2011, 71:1591-1622.
    • (2011) Drugs , vol.71 , pp. 1591-1622
    • Carter, N.J.1    Curran, M.P.2
  • 13
    • 33846816853 scopus 로고    scopus 로고
    • Edward Jenner and the history of smallpox and vaccination
    • Riedel S. Edward Jenner and the history of smallpox and vaccination. Proc. (Baylor Univ. Med. Cent.) 2005, 18:21-25.
    • (2005) Proc. (Baylor Univ. Med. Cent.) , vol.18 , pp. 21-25
    • Riedel, S.1
  • 15
    • 84908079915 scopus 로고    scopus 로고
    • Achieving and maintaining polio eradication-new strategies
    • Modlin J., Wenger J. Achieving and maintaining polio eradication-new strategies. N. Engl. J. Med. 2014, 371:1476-1479.
    • (2014) N. Engl. J. Med. , vol.371 , pp. 1476-1479
    • Modlin, J.1    Wenger, J.2
  • 17
    • 77957375946 scopus 로고    scopus 로고
    • Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine
    • Levine M.M. Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine. BMC Biol. 2010, 8:129.
    • (2010) BMC Biol. , vol.8 , pp. 129
    • Levine, M.M.1
  • 18
    • 17144390274 scopus 로고    scopus 로고
    • Considerations for development of whole cell bacterial vaccines to prevent diarrheal diseases in children in developing countries
    • Walker R.I. Considerations for development of whole cell bacterial vaccines to prevent diarrheal diseases in children in developing countries. Vaccine 2005, 23:3369-3385.
    • (2005) Vaccine , vol.23 , pp. 3369-3385
    • Walker, R.I.1
  • 19
    • 84864338756 scopus 로고    scopus 로고
    • Recent progress in mucosal vaccine development: potential and limitations
    • Lycke N. Recent progress in mucosal vaccine development: potential and limitations. Nat. Rev. Immunol. 2012, 12:592-605.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 592-605
    • Lycke, N.1
  • 20
    • 0032499485 scopus 로고    scopus 로고
    • Optimism over vaccines administered via mucosal surfaces
    • Levine M.M., Dougan G. Optimism over vaccines administered via mucosal surfaces. Lancet 1998, 351:1375-1376.
    • (1998) Lancet , vol.351 , pp. 1375-1376
    • Levine, M.M.1    Dougan, G.2
  • 21
    • 68049124726 scopus 로고    scopus 로고
    • Mucosal vaccines: novel advances in technology and delivery
    • Yuki Y., Kiyono H. Mucosal vaccines: novel advances in technology and delivery. Expert Rev. Vaccines 2009, 8:1083-1097.
    • (2009) Expert Rev. Vaccines , vol.8 , pp. 1083-1097
    • Yuki, Y.1    Kiyono, H.2
  • 23
    • 84875957998 scopus 로고    scopus 로고
    • An approach to a cold chain free oral cholera vaccine: in vitro and in vivo characterization of Vibrio cholerae gastro-resistant microparticles
    • Pastor M., Esquisabel A., Talavera A., Ano G., Fernandez S., Cedre B., Infante J.F., Callico A., Pedraz J.L. An approach to a cold chain free oral cholera vaccine: in vitro and in vivo characterization of Vibrio cholerae gastro-resistant microparticles. Int. J. Pharm. 2013, 448:247-258.
    • (2013) Int. J. Pharm. , vol.448 , pp. 247-258
    • Pastor, M.1    Esquisabel, A.2    Talavera, A.3    Ano, G.4    Fernandez, S.5    Cedre, B.6    Infante, J.F.7    Callico, A.8    Pedraz, J.L.9
  • 24
    • 0030000550 scopus 로고    scopus 로고
    • Antigen sampling across epithelial barriers and induction of mucosal immune responses
    • Neutra M.R., Pringault E., Kraehenbuhl J.P. Antigen sampling across epithelial barriers and induction of mucosal immune responses. Annu. Rev. Immunol. 1996, 14:275-300.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 275-300
    • Neutra, M.R.1    Pringault, E.2    Kraehenbuhl, J.P.3
  • 25
    • 17644371966 scopus 로고    scopus 로고
    • Mucosal immunity and vaccines
    • Holmgren J., Czerkinsky C. Mucosal immunity and vaccines. Nat. Med. 2005, 11:S45-S53.
    • (2005) Nat. Med. , vol.11 , pp. S45-S53
    • Holmgren, J.1    Czerkinsky, C.2
  • 27
    • 84908336634 scopus 로고    scopus 로고
    • Effect of a single inactivated poliovirus vaccine dose on intestinal immunity against poliovirus in children previously given oral vaccine: an open-label, randomised controlled trial
    • John J., Giri S., Karthikeyan A.S., Iturriza-Gomara M., Muliyil J., Abraham A., Grassly N.C., Kang G. Effect of a single inactivated poliovirus vaccine dose on intestinal immunity against poliovirus in children previously given oral vaccine: an open-label, randomised controlled trial. Lancet 2014, 384:1505-1512.
    • (2014) Lancet , vol.384 , pp. 1505-1512
    • John, J.1    Giri, S.2    Karthikeyan, A.S.3    Iturriza-Gomara, M.4    Muliyil, J.5    Abraham, A.6    Grassly, N.C.7    Kang, G.8
  • 29
    • 43549117511 scopus 로고    scopus 로고
    • The mucosal immune system at the gastrointestinal barrier
    • Schenk M., Mueller C. The mucosal immune system at the gastrointestinal barrier. Best Pract. Res. Clin. Gastroenterol. 2008, 22:391-409.
    • (2008) Best Pract. Res. Clin. Gastroenterol. , vol.22 , pp. 391-409
    • Schenk, M.1    Mueller, C.2
  • 31
    • 60149089459 scopus 로고    scopus 로고
    • Barrier properties of mucus
    • Cone R.A. Barrier properties of mucus. Adv. Drug Deliv. Rev. 2009, 61:75-85.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 75-85
    • Cone, R.A.1
  • 33
    • 60149111908 scopus 로고    scopus 로고
    • Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
    • Lai S.K., Wang Y.Y., Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv. Drug Deliv. Rev. 2009, 61:158-171.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 158-171
    • Lai, S.K.1    Wang, Y.Y.2    Hanes, J.3
  • 34
    • 84921786777 scopus 로고    scopus 로고
    • Regional specialization within the intestinal immune system
    • Mowat A.M., Agace W.W. Regional specialization within the intestinal immune system. Nat. Rev. Immunol. 2014, 14:667-685.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 667-685
    • Mowat, A.M.1    Agace, W.W.2
  • 35
    • 70350306659 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus
    • Lai S.K., Hida K., Shukair S., Wang Y.Y., Figueiredo A., Cone R., Hope T.J., Hanes J. Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus. J. Virol. 2009, 83:11196-11200.
    • (2009) J. Virol. , vol.83 , pp. 11196-11200
    • Lai, S.K.1    Hida, K.2    Shukair, S.3    Wang, Y.Y.4    Figueiredo, A.5    Cone, R.6    Hope, T.J.7    Hanes, J.8
  • 36
    • 33644836224 scopus 로고    scopus 로고
    • Mucosal vaccines: the promise and the challenge
    • Neutra M.R., Kozlowski P.A. Mucosal vaccines: the promise and the challenge. Nat. Rev. Immunol. 2006, 6:148-158.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 148-158
    • Neutra, M.R.1    Kozlowski, P.A.2
  • 37
    • 84883319282 scopus 로고    scopus 로고
    • Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches
    • Ermund A., Schutte A., Johansson M.E., Gustafsson J.K., Hansson G.C. Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches. Am. J. Physiol. Gastrointest. Liver Physiol. 2013, 305:G341-G347.
    • (2013) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.305 , pp. G341-G347
    • Ermund, A.1    Schutte, A.2    Johansson, M.E.3    Gustafsson, J.K.4    Hansson, G.C.5
  • 38
    • 0029055473 scopus 로고
    • Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals
    • Kararli T.T. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. Biopharm. Drug Dispos. 1995, 16:351-380.
    • (1995) Biopharm. Drug Dispos. , vol.16 , pp. 351-380
    • Kararli, T.T.1
  • 39
    • 47549117914 scopus 로고    scopus 로고
    • Determinants of responses to oral vaccines in developing countries
    • Sack D.A., Qadri F., Svennerholm A.M. Determinants of responses to oral vaccines in developing countries. Ann. Nestle Eng. 2008, 66:71-79.
    • (2008) Ann. Nestle Eng. , vol.66 , pp. 71-79
    • Sack, D.A.1    Qadri, F.2    Svennerholm, A.M.3
  • 41
    • 84927695047 scopus 로고    scopus 로고
    • Influence of the microbiota on vaccine effectiveness
    • Valdez Y., Brown E.M., Finlay B.B. Influence of the microbiota on vaccine effectiveness. Trends Immunol. 2014, 35:526-537.
    • (2014) Trends Immunol. , vol.35 , pp. 526-537
    • Valdez, Y.1    Brown, E.M.2    Finlay, B.B.3
  • 45
    • 0031824696 scopus 로고    scopus 로고
    • Interactions of the invasive pathogens Salmonella typhimurium, Listeria monocytogenes, and Shigella flexneri with M cells and murine Peyer's patches
    • Jensen V.B., Harty J.T., Jones B.D. Interactions of the invasive pathogens Salmonella typhimurium, Listeria monocytogenes, and Shigella flexneri with M cells and murine Peyer's patches. Infect. Immun. 1998, 66:3758-3766.
    • (1998) Infect. Immun. , vol.66 , pp. 3758-3766
    • Jensen, V.B.1    Harty, J.T.2    Jones, B.D.3
  • 47
    • 0030576516 scopus 로고    scopus 로고
    • Epithelial M cells: gateways for mucosal infection and immunization
    • Neutra M.R., Frey A., Kraehenbuhl J.P. Epithelial M cells: gateways for mucosal infection and immunization. Cell 1996, 86:345-348.
    • (1996) Cell , vol.86 , pp. 345-348
    • Neutra, M.R.1    Frey, A.2    Kraehenbuhl, J.P.3
  • 48
    • 84879336857 scopus 로고    scopus 로고
    • Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium
    • Mabbott N.A., Donaldson D.S., Ohno H., Williams I.R., Mahajan A. Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium. Mucosal Immunol. 2013, 6:666-677.
    • (2013) Mucosal Immunol. , vol.6 , pp. 666-677
    • Mabbott, N.A.1    Donaldson, D.S.2    Ohno, H.3    Williams, I.R.4    Mahajan, A.5
  • 49
    • 77949742766 scopus 로고    scopus 로고
    • Microencapsulation of vaccine antigens and adjuvants for mucosal targeting
    • Thejani D.D.L., Rajapaksa E. Microencapsulation of vaccine antigens and adjuvants for mucosal targeting. Curr. Immunol. Rev. 2010, 6:29-37.
    • (2010) Curr. Immunol. Rev. , vol.6 , pp. 29-37
    • Thejani, D.D.L.1    Rajapaksa, E.2
  • 51
    • 0015097333 scopus 로고
    • Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit
    • Craig S.W., Cebra J.J. Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit. J. Exp. Med. 1971, 134:188-200.
    • (1971) J. Exp. Med. , vol.134 , pp. 188-200
    • Craig, S.W.1    Cebra, J.J.2
  • 52
    • 2442479518 scopus 로고    scopus 로고
    • IgA class switch occurs in the organized nasopharynx- and gut-associated lymphoid tissue, but not in the diffuse lamina propria of airways and gut
    • Shikina T., Hiroi T., Iwatani K., Jang M.H., Fukuyama S., Tamura M., Kubo T., Ishikawa H., Kiyono H. IgA class switch occurs in the organized nasopharynx- and gut-associated lymphoid tissue, but not in the diffuse lamina propria of airways and gut. J. Immunol. 2004, 172:6259-6264.
    • (2004) J. Immunol. , vol.172 , pp. 6259-6264
    • Shikina, T.1    Hiroi, T.2    Iwatani, K.3    Jang, M.H.4    Fukuyama, S.5    Tamura, M.6    Kubo, T.7    Ishikawa, H.8    Kiyono, H.9
  • 55
    • 84857635052 scopus 로고    scopus 로고
    • Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores
    • Lelouard H., Fallet M., de Bovis B., Meresse S., Gorvel J.P. Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores. Gastroenterology 2012, 142:592-601.e593.
    • (2012) Gastroenterology , vol.142 , pp. 592-601.e593
    • Lelouard, H.1    Fallet, M.2    de Bovis, B.3    Meresse, S.4    Gorvel, J.P.5
  • 61
    • 38849145753 scopus 로고    scopus 로고
    • Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment
    • Kadaoui K.A., Corthesy B. Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment. J. Immunol. 2007, 179:7751-7757.
    • (2007) J. Immunol. , vol.179 , pp. 7751-7757
    • Kadaoui, K.A.1    Corthesy, B.2
  • 62
    • 1342303390 scopus 로고    scopus 로고
    • Targeting of secretory IgA to Peyer's patch dendritic and T cells after transport by intestinal M cells
    • Rey J., Garin N., Spertini F., Corthesy B. Targeting of secretory IgA to Peyer's patch dendritic and T cells after transport by intestinal M cells. J. Immunol. 2004, 172:3026-3033.
    • (2004) J. Immunol. , vol.172 , pp. 3026-3033
    • Rey, J.1    Garin, N.2    Spertini, F.3    Corthesy, B.4
  • 64
    • 34147165044 scopus 로고    scopus 로고
    • Solitary intestinal lymphoid tissue provides a productive port of entry for Salmonella enterica serovar Typhimurium
    • Halle S., Bumann D., Herbrand H., Willer Y., Dahne S., Forster R., Pabst O. Solitary intestinal lymphoid tissue provides a productive port of entry for Salmonella enterica serovar Typhimurium. Infect. Immun. 2007, 75:1577-1585.
    • (2007) Infect. Immun. , vol.75 , pp. 1577-1585
    • Halle, S.1    Bumann, D.2    Herbrand, H.3    Willer, Y.4    Dahne, S.5    Forster, R.6    Pabst, O.7
  • 65
    • 37049033289 scopus 로고    scopus 로고
    • Entry route of Salmonella typhimurium directs the type of induced immune response
    • Martinoli C., Chiavelli A., Rescigno M. Entry route of Salmonella typhimurium directs the type of induced immune response. Immunity 2007, 27:975-984.
    • (2007) Immunity , vol.27 , pp. 975-984
    • Martinoli, C.1    Chiavelli, A.2    Rescigno, M.3
  • 66
    • 14044262308 scopus 로고    scopus 로고
    • Two distinctive pathways for recruitment of naive and primed IgM+ B cells to the gut lamina propria
    • Suzuki K., Meek B., Doi Y., Honjo T., Fagarasan S. Two distinctive pathways for recruitment of naive and primed IgM+ B cells to the gut lamina propria. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:2482-2486.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 2482-2486
    • Suzuki, K.1    Meek, B.2    Doi, Y.3    Honjo, T.4    Fagarasan, S.5
  • 67
    • 48749091530 scopus 로고    scopus 로고
    • Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut
    • Tsuji M., Suzuki K., Kitamura H., Maruya M., Kinoshita K., Ivanov I.I., Itoh K., Littman D.R., Fagarasan S. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity 2008, 29:261-271.
    • (2008) Immunity , vol.29 , pp. 261-271
    • Tsuji, M.1    Suzuki, K.2    Kitamura, H.3    Maruya, M.4    Kinoshita, K.5    Ivanov, I.I.6    Itoh, K.7    Littman, D.R.8    Fagarasan, S.9
  • 68
    • 41549131849 scopus 로고    scopus 로고
    • T follicular helper (TFH) cells in normal and dysregulated immune responses
    • King C., Tangye S.G., Mackay C.R. T follicular helper (TFH) cells in normal and dysregulated immune responses. Annu. Rev. Immunol. 2008, 26:741-766.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 741-766
    • King, C.1    Tangye, S.G.2    Mackay, C.R.3
  • 69
    • 1542618118 scopus 로고    scopus 로고
    • Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria
    • Macpherson A.J., Uhr T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 2004, 303:1662-1665.
    • (2004) Science , vol.303 , pp. 1662-1665
    • Macpherson, A.J.1    Uhr, T.2
  • 70
    • 0033584234 scopus 로고    scopus 로고
    • Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells
    • Iwasaki A., Kelsall B.L. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J. Exp. Med. 1999, 190:229-239.
    • (1999) J. Exp. Med. , vol.190 , pp. 229-239
    • Iwasaki, A.1    Kelsall, B.L.2
  • 72
    • 0141886178 scopus 로고    scopus 로고
    • CD11b+ Peyer's patch dendritic cells secrete IL-6 and induce IgA secretion from naive B cells
    • Sato A., Hashiguchi M., Toda E., Iwasaki A., Hachimura S., Kaminogawa S. CD11b+ Peyer's patch dendritic cells secrete IL-6 and induce IgA secretion from naive B cells. J. Immunol. 2003, 171:3684-3690.
    • (2003) J. Immunol. , vol.171 , pp. 3684-3690
    • Sato, A.1    Hashiguchi, M.2    Toda, E.3    Iwasaki, A.4    Hachimura, S.5    Kaminogawa, S.6
  • 73
    • 84874042768 scopus 로고    scopus 로고
    • The role of CD103(+) dendritic cells in the intestinal mucosal immune system
    • Ruane D.T., Lavelle E.C. The role of CD103(+) dendritic cells in the intestinal mucosal immune system. Front. Immunol. 2011, 2:25.
    • (2011) Front. Immunol. , vol.2 , pp. 25
    • Ruane, D.T.1    Lavelle, E.C.2
  • 74
    • 73949107838 scopus 로고    scopus 로고
    • Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions
    • Schulz O., Jaensson E., Persson E.K., Liu X., Worbs T., Agace W.W., Pabst O. Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions. J. Exp. Med. 2009, 206:3101-3114.
    • (2009) J. Exp. Med. , vol.206 , pp. 3101-3114
    • Schulz, O.1    Jaensson, E.2    Persson, E.K.3    Liu, X.4    Worbs, T.5    Agace, W.W.6    Pabst, O.7
  • 76
    • 80053061293 scopus 로고    scopus 로고
    • Mucosa-associated epithelial chemokine/CCL28 expression in the uterus attracts CCR10+ IgA plasma cells following mucosal vaccination via estrogen control
    • Cha H.R., Ko H.J., Kim E.D., Chang S.Y., Seo S.U., Cuburu N., Ryu S., Kim S., Kweon M.N. Mucosa-associated epithelial chemokine/CCL28 expression in the uterus attracts CCR10+ IgA plasma cells following mucosal vaccination via estrogen control. J. Immunol. 2011, 187:3044-3052.
    • (2011) J. Immunol. , vol.187 , pp. 3044-3052
    • Cha, H.R.1    Ko, H.J.2    Kim, E.D.3    Chang, S.Y.4    Seo, S.U.5    Cuburu, N.6    Ryu, S.7    Kim, S.8    Kweon, M.N.9
  • 77
    • 80051925503 scopus 로고    scopus 로고
    • Intestinal CD103+ dendritic cells: master regulators of tolerance?
    • Scott C.L., Aumeunier A.M., Mowat A.M. Intestinal CD103+ dendritic cells: master regulators of tolerance?. Trends Immunol. 2011, 32:412-419.
    • (2011) Trends Immunol. , vol.32 , pp. 412-419
    • Scott, C.L.1    Aumeunier, A.M.2    Mowat, A.M.3
  • 81
    • 48849115839 scopus 로고    scopus 로고
    • Differentiation and homing of IgA-secreting cells
    • Mora J.R., von Andrian U.H. Differentiation and homing of IgA-secreting cells. Mucosal Immunol. 2008, 1:96-109.
    • (2008) Mucosal Immunol. , vol.1 , pp. 96-109
    • Mora, J.R.1    von Andrian, U.H.2
  • 82
    • 33646483489 scopus 로고    scopus 로고
    • Redundant role of chemokines CCL25/TECK and CCL28/MEC in IgA+ plasmablast recruitment to the intestinal lamina propria after rotavirus infection
    • Feng N., Jaimes M.C., Lazarus N.H., Monak D., Zhang C., Butcher E.C., Greenberg H.B. Redundant role of chemokines CCL25/TECK and CCL28/MEC in IgA+ plasmablast recruitment to the intestinal lamina propria after rotavirus infection. J. Immunol. 2006, 176:5749-5759.
    • (2006) J. Immunol. , vol.176 , pp. 5749-5759
    • Feng, N.1    Jaimes, M.C.2    Lazarus, N.H.3    Monak, D.4    Zhang, C.5    Butcher, E.C.6    Greenberg, H.B.7
  • 83
    • 79956119017 scopus 로고    scopus 로고
    • Regional and mucosal memory T cells
    • Sheridan B.S., Lefrancois L. Regional and mucosal memory T cells. Nat. Immunol. 2011, 12:485-491.
    • (2011) Nat. Immunol. , vol.12 , pp. 485-491
    • Sheridan, B.S.1    Lefrancois, L.2
  • 84
    • 56249112586 scopus 로고    scopus 로고
    • Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells
    • Mora J.R., von Andrian U.H. Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells. Semin. Immunol. 2009, 21:28-35.
    • (2009) Semin. Immunol. , vol.21 , pp. 28-35
    • Mora, J.R.1    von Andrian, U.H.2
  • 85
    • 4544258068 scopus 로고    scopus 로고
    • NALT- versus Peyer's-patch-mediated mucosal immunity
    • Kiyono H., Fukuyama S. NALT- versus Peyer's-patch-mediated mucosal immunity. Nat. Rev. Immunol. 2004, 4:699-710.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 699-710
    • Kiyono, H.1    Fukuyama, S.2
  • 86
    • 77952203545 scopus 로고    scopus 로고
    • Function of mucosa-associated lymphoid tissue in antibody formation
    • Brandtzaeg P. Function of mucosa-associated lymphoid tissue in antibody formation. Immunol. Invest. 2010, 39:303-355.
    • (2010) Immunol. Invest. , vol.39 , pp. 303-355
    • Brandtzaeg, P.1
  • 87
    • 79955156446 scopus 로고    scopus 로고
    • Memory T cells as an occupying force
    • Bevan M.J. Memory T cells as an occupying force. Eur. J. Immunol. 2011, 41:1192-1195.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 1192-1195
    • Bevan, M.J.1
  • 88
    • 77953537389 scopus 로고    scopus 로고
    • Th17 cytokines and the gut mucosal barrier
    • Blaschitz C., Raffatellu M. Th17 cytokines and the gut mucosal barrier. J. Clin. Immunol. 2010, 30:196-203.
    • (2010) J. Clin. Immunol. , vol.30 , pp. 196-203
    • Blaschitz, C.1    Raffatellu, M.2
  • 89
    • 78650840359 scopus 로고    scopus 로고
    • Adaptive immunity in the host-microbiota dialog
    • Feng T., Elson C.O. Adaptive immunity in the host-microbiota dialog. Mucosal Immunol. 2011, 4:15-21.
    • (2011) Mucosal Immunol. , vol.4 , pp. 15-21
    • Feng, T.1    Elson, C.O.2
  • 91
    • 23344433145 scopus 로고    scopus 로고
    • The polymeric immunoglobulin receptor: bridging innate and adaptive immune responses at mucosal surfaces
    • Kaetzel C.S. The polymeric immunoglobulin receptor: bridging innate and adaptive immune responses at mucosal surfaces. Immunol. Rev. 2005, 206:83-99.
    • (2005) Immunol. Rev. , vol.206 , pp. 83-99
    • Kaetzel, C.S.1
  • 92
    • 0030014069 scopus 로고    scopus 로고
    • Biological significance of IgA1 proteases in bacterial colonization and pathogenesis: critical evaluation of experimental evidence
    • Kilian M., Reinholdt J., Lomholt H., Poulsen K., Frandsen E.V. Biological significance of IgA1 proteases in bacterial colonization and pathogenesis: critical evaluation of experimental evidence. APMIS 1996, 104:321-338.
    • (1996) APMIS , vol.104 , pp. 321-338
    • Kilian, M.1    Reinholdt, J.2    Lomholt, H.3    Poulsen, K.4    Frandsen, E.V.5
  • 93
    • 77952149753 scopus 로고    scopus 로고
    • Secretory IgA: arresting microbial pathogens at epithelial borders
    • Mantis N.J., Forbes S.J. Secretory IgA: arresting microbial pathogens at epithelial borders. Immunol. Invest. 2010, 39:383-406.
    • (2010) Immunol. Invest. , vol.39 , pp. 383-406
    • Mantis, N.J.1    Forbes, S.J.2
  • 94
    • 34447099136 scopus 로고    scopus 로고
    • Induction of secretory immunity and memory at mucosal surfaces
    • Brandtzaeg P. Induction of secretory immunity and memory at mucosal surfaces. Vaccine 2007, 25:5467-5484.
    • (2007) Vaccine , vol.25 , pp. 5467-5484
    • Brandtzaeg, P.1
  • 95
    • 84870252354 scopus 로고    scopus 로고
    • New concepts in the generation and functions of IgA
    • Pabst O. New concepts in the generation and functions of IgA. Nat. Rev. Immunol. 2012, 12:821-832.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 821-832
    • Pabst, O.1
  • 99
    • 20544472058 scopus 로고    scopus 로고
    • Virulence factors, pathogenesis and vaccine protection in cholera and ETEC diarrhea
    • Sanchez J., Holmgren J. Virulence factors, pathogenesis and vaccine protection in cholera and ETEC diarrhea. Curr. Opin. Immunol. 2005, 17:388-398.
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 388-398
    • Sanchez, J.1    Holmgren, J.2
  • 100
    • 0035074535 scopus 로고    scopus 로고
    • Vaccination strategies for mucosal immune responses
    • Ogra P.L., Faden H., Welliver R.C. Vaccination strategies for mucosal immune responses. Clin. Microbiol. Rev. 2001, 14:430-445.
    • (2001) Clin. Microbiol. Rev. , vol.14 , pp. 430-445
    • Ogra, P.L.1    Faden, H.2    Welliver, R.C.3
  • 101
    • 84877034427 scopus 로고    scopus 로고
    • Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant
    • Holmgren J., Bourgeois L., Carlin N., Clements J., Gustafsson B., Lundgren A., Nygren E., Tobias J., Walker R., Svennerholm A.M. Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant. Vaccine 2013, 31:2457-2464.
    • (2013) Vaccine , vol.31 , pp. 2457-2464
    • Holmgren, J.1    Bourgeois, L.2    Carlin, N.3    Clements, J.4    Gustafsson, B.5    Lundgren, A.6    Nygren, E.7    Tobias, J.8    Walker, R.9    Svennerholm, A.M.10
  • 102
    • 84873100213 scopus 로고    scopus 로고
    • Clinical trial to evaluate safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli prototype vaccine containing CFA/I overexpressing bacteria and recombinantly produced LTB/CTB hybrid protein
    • Lundgren A., Leach S., Tobias J., Carlin N., Gustafsson B., Jertborn M., Bourgeois L., Walker R., Holmgren J., Svennerholm A.M. Clinical trial to evaluate safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli prototype vaccine containing CFA/I overexpressing bacteria and recombinantly produced LTB/CTB hybrid protein. Vaccine 2013, 31:1163-1170.
    • (2013) Vaccine , vol.31 , pp. 1163-1170
    • Lundgren, A.1    Leach, S.2    Tobias, J.3    Carlin, N.4    Gustafsson, B.5    Jertborn, M.6    Bourgeois, L.7    Walker, R.8    Holmgren, J.9    Svennerholm, A.M.10
  • 103
    • 38349049215 scopus 로고    scopus 로고
    • Construction of non-toxic Escherichia coli and Vibrio cholerae strains expressing high and immunogenic levels of enterotoxigenic E. coli colonization factor I fimbriae
    • Tobias J., Lebens M., Bolin I., Wiklund G., Svennerholm A.M. Construction of non-toxic Escherichia coli and Vibrio cholerae strains expressing high and immunogenic levels of enterotoxigenic E. coli colonization factor I fimbriae. Vaccine 2008, 26:743-752.
    • (2008) Vaccine , vol.26 , pp. 743-752
    • Tobias, J.1    Lebens, M.2    Bolin, I.3    Wiklund, G.4    Svennerholm, A.M.5
  • 104
    • 84915745692 scopus 로고    scopus 로고
    • Development of Stable Vibrio cholerae O1 Hikojima Type Vaccine Strains Co-Expressing the Inaba and Ogawa Lipopolysaccharide Antigens
    • Karlsson S.L., Ax E., Nygren E., Kallgard S., Blomquist M., Ekman A., Benktander J., Holmgren J., Lebens M. Development of Stable Vibrio cholerae O1 Hikojima Type Vaccine Strains Co-Expressing the Inaba and Ogawa Lipopolysaccharide Antigens. PLoS ONE 2014, 9:e108521.
    • (2014) PLoS ONE , vol.9 , pp. e108521
    • Karlsson, S.L.1    Ax, E.2    Nygren, E.3    Kallgard, S.4    Blomquist, M.5    Ekman, A.6    Benktander, J.7    Holmgren, J.8    Lebens, M.9
  • 109
    • 84940956928 scopus 로고    scopus 로고
    • New approaches in oral rotavirus vaccines
    • Kuate Defo Z., Lee B. New approaches in oral rotavirus vaccines. Crit. Rev. Microbiol. 2014, 1-11.
    • (2014) Crit. Rev. Microbiol. , pp. 1-11
    • Kuate Defo, Z.1    Lee, B.2
  • 111
    • 0033055636 scopus 로고    scopus 로고
    • Membrane traffic and the cellular uptake of cholera toxin
    • Lencer W.I., Hirst T.R., Holmes R.K. Membrane traffic and the cellular uptake of cholera toxin. Biochim. Biophys. Acta 1999, 1450:177-190.
    • (1999) Biochim. Biophys. Acta , vol.1450 , pp. 177-190
    • Lencer, W.I.1    Hirst, T.R.2    Holmes, R.K.3
  • 113
    • 77958155475 scopus 로고    scopus 로고
    • Use of genetically or chemically detoxified mutants of cholera and Escherichia coli heat-labile enterotoxins as mucosal adjuvants
    • Freytag L.C., Clements J.D., Eliasson D.G., Lycke N. Use of genetically or chemically detoxified mutants of cholera and Escherichia coli heat-labile enterotoxins as mucosal adjuvants. New generation vaccines 2010, 273-283.
    • (2010) New generation vaccines , pp. 273-283
    • Freytag, L.C.1    Clements, J.D.2    Eliasson, D.G.3    Lycke, N.4
  • 114
    • 0026458260 scopus 로고
    • Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
    • Spangler B.D. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol. Rev. 1992, 56:622-647.
    • (1992) Microbiol. Rev. , vol.56 , pp. 622-647
    • Spangler, B.D.1
  • 115
    • 0029493562 scopus 로고
    • The mucosal adjuvant activities of ADP-ribosylating bacterial enterotoxins
    • Snider D.P. The mucosal adjuvant activities of ADP-ribosylating bacterial enterotoxins. Crit. Rev. Immunol. 1995, 15:317-348.
    • (1995) Crit. Rev. Immunol. , vol.15 , pp. 317-348
    • Snider, D.P.1
  • 116
  • 119
    • 0035888201 scopus 로고    scopus 로고
    • Pre-clinical and clinical investigation of the safety of a novel adjuvant for intranasal immunization
    • Glueck R. Pre-clinical and clinical investigation of the safety of a novel adjuvant for intranasal immunization. Vaccine 2001, 20(Suppl. 1):S42-S44.
    • (2001) Vaccine , vol.20 , pp. S42-S44
    • Glueck, R.1
  • 120
    • 0037035853 scopus 로고    scopus 로고
    • A dilemma for mucosal vaccination: efficacy versus toxicity using enterotoxin-based adjuvants
    • Fujihashi K., Koga T., van Ginkel F.W., Hagiwara Y., McGhee J.R. A dilemma for mucosal vaccination: efficacy versus toxicity using enterotoxin-based adjuvants. Vaccine 2002, 20:2431-2438.
    • (2002) Vaccine , vol.20 , pp. 2431-2438
    • Fujihashi, K.1    Koga, T.2    van Ginkel, F.W.3    Hagiwara, Y.4    McGhee, J.R.5
  • 121
  • 123
    • 79956215858 scopus 로고    scopus 로고
    • Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production
    • Brereton C.F., Sutton C.E., Ross P.J., Iwakura Y., Pizza M., Rappuoli R., Lavelle E.C., Mills K.H. Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production. J. Immunol. 2011, 186:5896-5906.
    • (2011) J. Immunol. , vol.186 , pp. 5896-5906
    • Brereton, C.F.1    Sutton, C.E.2    Ross, P.J.3    Iwakura, Y.4    Pizza, M.5    Rappuoli, R.6    Lavelle, E.C.7    Mills, K.H.8
  • 124
    • 0032728547 scopus 로고    scopus 로고
    • Mutants of Escherichia coli heat-labile toxin act as effective mucosal adjuvants for nasal delivery of an acellular pertussis vaccine: differential effects of the nontoxic AB complex and enzyme activity on Th1 and Th2 cells
    • Ryan E.J., McNeela E., Murphy G.A., Stewart H., O'Hagan D., Pizza M., Rappuoli R., Mills K.H. Mutants of Escherichia coli heat-labile toxin act as effective mucosal adjuvants for nasal delivery of an acellular pertussis vaccine: differential effects of the nontoxic AB complex and enzyme activity on Th1 and Th2 cells. Infect. Immun. 1999, 67:6270-6280.
    • (1999) Infect. Immun. , vol.67 , pp. 6270-6280
    • Ryan, E.J.1    McNeela, E.2    Murphy, G.A.3    Stewart, H.4    O'Hagan, D.5    Pizza, M.6    Rappuoli, R.7    Mills, K.H.8
  • 125
    • 0032755492 scopus 로고    scopus 로고
    • Intranasal immunization with pneumococcal polysaccharide conjugate vaccines with nontoxic mutants of Escherichia coli heat-labile enterotoxins as adjuvants protects mice against invasive pneumococcal infections
    • Jakobsen H., Schulz D., Pizza M., Rappuoli R., Jonsdottir I. Intranasal immunization with pneumococcal polysaccharide conjugate vaccines with nontoxic mutants of Escherichia coli heat-labile enterotoxins as adjuvants protects mice against invasive pneumococcal infections. Infect. Immun. 1999, 67:5892-5897.
    • (1999) Infect. Immun. , vol.67 , pp. 5892-5897
    • Jakobsen, H.1    Schulz, D.2    Pizza, M.3    Rappuoli, R.4    Jonsdottir, I.5
  • 126
    • 0033797049 scopus 로고    scopus 로고
    • Genetically detoxified mutants of heat-labile enterotoxin from Escherichia coli are effective adjuvants for induction of cytotoxic T-cell responses against HIV-1 gag-p55
    • Neidleman J.A., Vajdy M., Ugozzoli M., Ott G., O'Hagan D. Genetically detoxified mutants of heat-labile enterotoxin from Escherichia coli are effective adjuvants for induction of cytotoxic T-cell responses against HIV-1 gag-p55. Immunology 2000, 101:154-160.
    • (2000) Immunology , vol.101 , pp. 154-160
    • Neidleman, J.A.1    Vajdy, M.2    Ugozzoli, M.3    Ott, G.4    O'Hagan, D.5
  • 128
    • 84871417768 scopus 로고    scopus 로고
    • The adjuvant double mutant Escherichia coli heat labile toxin enhances IL-17A production in human T cells specific for bacterial vaccine antigens
    • Leach S., Clements J.D., Kaim J., Lundgren A. The adjuvant double mutant Escherichia coli heat labile toxin enhances IL-17A production in human T cells specific for bacterial vaccine antigens. PLoS ONE 2012, 7:e51718.
    • (2012) PLoS ONE , vol.7 , pp. e51718
    • Leach, S.1    Clements, J.D.2    Kaim, J.3    Lundgren, A.4
  • 129
    • 84877795556 scopus 로고    scopus 로고
    • A double mutant heat-labile toxin from Escherichia coli, LT(R192G/L211A), is an effective mucosal adjuvant for vaccination against Helicobacter pylori infection
    • Sjokvist Ottsjo L., Flach C.F., Clements J., Holmgren J., Raghavan S. A double mutant heat-labile toxin from Escherichia coli, LT(R192G/L211A), is an effective mucosal adjuvant for vaccination against Helicobacter pylori infection. Infect. Immun. 2013, 81:1532-1540.
    • (2013) Infect. Immun. , vol.81 , pp. 1532-1540
    • Sjokvist Ottsjo, L.1    Flach, C.F.2    Clements, J.3    Holmgren, J.4    Raghavan, S.5
  • 130
    • 84915775542 scopus 로고    scopus 로고
    • Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I study
    • Lundgren A., Bourgeois L., Carlin N., Clements J., Gustafsson B., Hartford M., Holmgren J., Petzold M., Walker R., Svennerholm A.M. Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I study. Vaccine 2014, 32:7077-7084.
    • (2014) Vaccine , vol.32 , pp. 7077-7084
    • Lundgren, A.1    Bourgeois, L.2    Carlin, N.3    Clements, J.4    Gustafsson, B.5    Hartford, M.6    Holmgren, J.7    Petzold, M.8    Walker, R.9    Svennerholm, A.M.10
  • 131
    • 0031569528 scopus 로고    scopus 로고
    • Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit
    • Agren L.C., Ekman L., Lowenadler B., Lycke N.Y. Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit. J. Immunol. 1997, 158:3936-3946.
    • (1997) J. Immunol. , vol.158 , pp. 3936-3946
    • Agren, L.C.1    Ekman, L.2    Lowenadler, B.3    Lycke, N.Y.4
  • 132
    • 77958195796 scopus 로고    scopus 로고
    • Mucosal adjuvants and long-term memory development with special focus on CTA1-DD and other ADP-ribosylating toxins
    • Lycke N., Bemark M. Mucosal adjuvants and long-term memory development with special focus on CTA1-DD and other ADP-ribosylating toxins. Mucosal Immunol. 2010, 3:556-566.
    • (2010) Mucosal Immunol. , vol.3 , pp. 556-566
    • Lycke, N.1    Bemark, M.2
  • 133
    • 4344665014 scopus 로고    scopus 로고
    • The cholera toxin-derived CTA1-DD vaccine adjuvant administered intranasally does not cause inflammation or accumulate in the nervous tissues
    • Eriksson A.M., Schon K.M., Lycke N.Y. The cholera toxin-derived CTA1-DD vaccine adjuvant administered intranasally does not cause inflammation or accumulate in the nervous tissues. J. Immunol. 2004, 173:3310-3319.
    • (2004) J. Immunol. , vol.173 , pp. 3310-3319
    • Eriksson, A.M.1    Schon, K.M.2    Lycke, N.Y.3
  • 134
    • 58149401439 scopus 로고    scopus 로고
    • CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization
    • Sundling C., Schon K., Morner A., Forsell M.N., Wyatt R.T., Thorstensson R., Karlsson Hedestam G.B., Lycke N.Y. CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization. J. Gen. Virol. 2008, 89:2954-2964.
    • (2008) J. Gen. Virol. , vol.89 , pp. 2954-2964
    • Sundling, C.1    Schon, K.2    Morner, A.3    Forsell, M.N.4    Wyatt, R.T.5    Thorstensson, R.6    Karlsson Hedestam, G.B.7    Lycke, N.Y.8
  • 135
    • 84908341893 scopus 로고    scopus 로고
    • Harnessing the antibacterial and immunological properties of Mucosal-associated invariant T cells in the development of novel oral vaccines against enteric infections
    • Abautret-Daly A.E., Davitt C.J., Lavelle E.C. Harnessing the antibacterial and immunological properties of Mucosal-associated invariant T cells in the development of novel oral vaccines against enteric infections. Biochem. Pharmacol. 2014, 92:173-183.
    • (2014) Biochem. Pharmacol. , vol.92 , pp. 173-183
    • Abautret-Daly, A.E.1    Davitt, C.J.2    Lavelle, E.C.3
  • 136
    • 77953539101 scopus 로고    scopus 로고
    • Synthetic iNKT cell-agonists as vaccine adjuvants-finding the balance
    • Cerundolo V., Barral P., Batista F.D. Synthetic iNKT cell-agonists as vaccine adjuvants-finding the balance. Curr. Opin. Immunol. 2010, 22:417-424.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 417-424
    • Cerundolo, V.1    Barral, P.2    Batista, F.D.3
  • 137
    • 84871718854 scopus 로고    scopus 로고
    • Induction of CD8+ regulatory T cells protects macaques against SIV challenge
    • Lu W., Chen S., Lai C., Guo W., Fu L., Andrieu J.M. Induction of CD8+ regulatory T cells protects macaques against SIV challenge. Cell Rep. 2012, 2:1736-1746.
    • (2012) Cell Rep. , vol.2 , pp. 1736-1746
    • Lu, W.1    Chen, S.2    Lai, C.3    Guo, W.4    Fu, L.5    Andrieu, J.M.6
  • 138
    • 84861963478 scopus 로고    scopus 로고
    • The mechanism of action of MF59 - an innately attractive adjuvant formulation
    • O'Hagan D.T., Ott G.S., De Gregorio E., Seubert A. The mechanism of action of MF59 - an innately attractive adjuvant formulation. Vaccine 2012, 30:4341-4348.
    • (2012) Vaccine , vol.30 , pp. 4341-4348
    • O'Hagan, D.T.1    Ott, G.S.2    De Gregorio, E.3    Seubert, A.4
  • 139
    • 0035937592 scopus 로고    scopus 로고
    • Block copolymer micelles for drug delivery: design, characterization and biological significance
    • Kataoka K., Harada A., Nagasaki Y. Block copolymer micelles for drug delivery: design, characterization and biological significance. Adv. Drug Deliv. Rev. 2001, 47:113-131.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 113-131
    • Kataoka, K.1    Harada, A.2    Nagasaki, Y.3
  • 143
    • 84865758788 scopus 로고    scopus 로고
    • Lipid-based nanocarriers as an alternative for oral delivery of poorly water- soluble drugs: peroral and mucosal routes
    • Silva A.C., Santos D., Ferreira D., Lopes C.M. Lipid-based nanocarriers as an alternative for oral delivery of poorly water- soluble drugs: peroral and mucosal routes. Curr. Med. Chem. 2012, 19:4495-4510.
    • (2012) Curr. Med. Chem. , vol.19 , pp. 4495-4510
    • Silva, A.C.1    Santos, D.2    Ferreira, D.3    Lopes, C.M.4
  • 145
    • 2342625401 scopus 로고    scopus 로고
    • Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition
    • Foged C., Arigita C., Sundblad A., Jiskoot W., Storm G., Frokjaer S. Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition. Vaccine 2004, 22:1903-1913.
    • (2004) Vaccine , vol.22 , pp. 1903-1913
    • Foged, C.1    Arigita, C.2    Sundblad, A.3    Jiskoot, W.4    Storm, G.5    Frokjaer, S.6
  • 148
    • 70349188458 scopus 로고    scopus 로고
    • A novel liposome-based adjuvant CAF01 for induction of CD8(+) cytotoxic T-lymphocytes (CTL) to HIV-1 minimal CTL peptides in HLA-A*0201 transgenic mice
    • Gram G.J., Karlsson I., Agger E.M., Andersen P., Fomsgaard A. A novel liposome-based adjuvant CAF01 for induction of CD8(+) cytotoxic T-lymphocytes (CTL) to HIV-1 minimal CTL peptides in HLA-A*0201 transgenic mice. PLoS ONE 2009, 4:e6950.
    • (2009) PLoS ONE , vol.4 , pp. e6950
    • Gram, G.J.1    Karlsson, I.2    Agger, E.M.3    Andersen, P.4    Fomsgaard, A.5
  • 149
    • 66749092107 scopus 로고    scopus 로고
    • A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells
    • Kamath A.T., Rochat A.F., Christensen D., Agger E.M., Andersen P., Lambert P.H., Siegrist C.A. A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells. PLoS ONE 2009, 4:e5771.
    • (2009) PLoS ONE , vol.4 , pp. e5771
    • Kamath, A.T.1    Rochat, A.F.2    Christensen, D.3    Agger, E.M.4    Andersen, P.5    Lambert, P.H.6    Siegrist, C.A.7
  • 150
    • 50949133667 scopus 로고    scopus 로고
    • Liposome delivery of Chlamydia muridarum major outer membrane protein primes a Th1 response that protects against genital chlamydial infection in a mouse model
    • Hansen J., Jensen K.T., Follmann F., Agger E.M., Theisen M., Andersen P. Liposome delivery of Chlamydia muridarum major outer membrane protein primes a Th1 response that protects against genital chlamydial infection in a mouse model. J. Infect. Dis. 2008, 198:758-767.
    • (2008) J. Infect. Dis. , vol.198 , pp. 758-767
    • Hansen, J.1    Jensen, K.T.2    Follmann, F.3    Agger, E.M.4    Theisen, M.5    Andersen, P.6
  • 152
    • 80955177124 scopus 로고    scopus 로고
    • Mucosal immunization with liposome-nucleic acid adjuvants generates effective humoral and cellular immunity
    • Henderson A., Propst K., Kedl R., Dow S. Mucosal immunization with liposome-nucleic acid adjuvants generates effective humoral and cellular immunity. Vaccine 2011, 29:5304-5312.
    • (2011) Vaccine , vol.29 , pp. 5304-5312
    • Henderson, A.1    Propst, K.2    Kedl, R.3    Dow, S.4
  • 154
    • 78650756605 scopus 로고    scopus 로고
    • Liposome-coupled antigens are internalized by antigen-presenting cells via pinocytosis and cross-presented to CD8 T cells
    • Tanaka Y., Taneichi M., Kasai M., Kakiuchi T., Uchida T. Liposome-coupled antigens are internalized by antigen-presenting cells via pinocytosis and cross-presented to CD8 T cells. PLoS ONE 2010, 5:e15225.
    • (2010) PLoS ONE , vol.5 , pp. e15225
    • Tanaka, Y.1    Taneichi, M.2    Kasai, M.3    Kakiuchi, T.4    Uchida, T.5
  • 155
    • 0029905843 scopus 로고    scopus 로고
    • Lectin-bearing polymerized liposomes as potential oral vaccine carriers
    • Chen H., Torchilin V., Langer R. Lectin-bearing polymerized liposomes as potential oral vaccine carriers. Pharm. Res. 1996, 13:1378-1383.
    • (1996) Pharm. Res. , vol.13 , pp. 1378-1383
    • Chen, H.1    Torchilin, V.2    Langer, R.3
  • 156
    • 0034255536 scopus 로고    scopus 로고
    • Polysaccharide coated liposomes for oral immunization-development and characterization
    • Venkatesan N., Vyas S.P. Polysaccharide coated liposomes for oral immunization-development and characterization. Int. J. Pharm. 2000, 203:169-177.
    • (2000) Int. J. Pharm. , vol.203 , pp. 169-177
    • Venkatesan, N.1    Vyas, S.P.2
  • 157
    • 67349087922 scopus 로고    scopus 로고
    • The path to a successful vaccine adjuvant-'the long and winding road'
    • O'Hagan D.T., De Gregorio E. The path to a successful vaccine adjuvant-'the long and winding road'. Drug Discov. Today 2009, 14:541-551.
    • (2009) Drug Discov. Today , vol.14 , pp. 541-551
    • O'Hagan, D.T.1    De Gregorio, E.2
  • 159
    • 0031730080 scopus 로고    scopus 로고
    • ISCOMs: an adjuvant with multiple functions
    • Sjolander A., Cox J.C., Barr I.G. ISCOMs: an adjuvant with multiple functions. J. Leukoc. Biol. 1998, 64:713-723.
    • (1998) J. Leukoc. Biol. , vol.64 , pp. 713-723
    • Sjolander, A.1    Cox, J.C.2    Barr, I.G.3
  • 163
    • 33744515008 scopus 로고    scopus 로고
    • Induction of protective and mucosal immunity against diphtheria by a immune stimulating complex (ISCOMS) based vaccine
    • Aguila A., Donachie A.M., Peyre M., McSharry C.P., Sesardic D., Mowat A.M. Induction of protective and mucosal immunity against diphtheria by a immune stimulating complex (ISCOMS) based vaccine. Vaccine 2006, 24:5201-5210.
    • (2006) Vaccine , vol.24 , pp. 5201-5210
    • Aguila, A.1    Donachie, A.M.2    Peyre, M.3    McSharry, C.P.4    Sesardic, D.5    Mowat, A.M.6
  • 164
    • 33845989506 scopus 로고    scopus 로고
    • The combined CTA1-DD/ISCOMs vector is an effective intranasal adjuvant for boosting prior Mycobacterium bovis BCG immunity to Mycobacterium tuberculosis
    • Andersen C.S., Dietrich J., Agger E.M., Lycke N.Y., Lovgren K., Andersen P. The combined CTA1-DD/ISCOMs vector is an effective intranasal adjuvant for boosting prior Mycobacterium bovis BCG immunity to Mycobacterium tuberculosis. Infect. Immun. 2007, 75:408-416.
    • (2007) Infect. Immun. , vol.75 , pp. 408-416
    • Andersen, C.S.1    Dietrich, J.2    Agger, E.M.3    Lycke, N.Y.4    Lovgren, K.5    Andersen, P.6
  • 166
    • 0023681347 scopus 로고
    • Polyvalent recombinant antigens: a new vaccine strategy
    • Kingsman S.M., Kingsman A.J. Polyvalent recombinant antigens: a new vaccine strategy. Vaccine 1988, 6:304-306.
    • (1988) Vaccine , vol.6 , pp. 304-306
    • Kingsman, S.M.1    Kingsman, A.J.2
  • 167
    • 84871650149 scopus 로고    scopus 로고
    • Construction and characterization of virus-like particles: a review
    • Zeltins A. Construction and characterization of virus-like particles: a review. Mol. Biotechnol. 2013, 53:92-107.
    • (2013) Mol. Biotechnol. , vol.53 , pp. 92-107
    • Zeltins, A.1
  • 168
    • 33748801527 scopus 로고    scopus 로고
    • Virus-like particles: designing an effective AIDS vaccine
    • Young K.R., McBurney S.P., Karkhanis L.U., Ross T.M. Virus-like particles: designing an effective AIDS vaccine. Methods 2006, 40:98-117.
    • (2006) Methods , vol.40 , pp. 98-117
    • Young, K.R.1    McBurney, S.P.2    Karkhanis, L.U.3    Ross, T.M.4
  • 170
    • 79952809503 scopus 로고    scopus 로고
    • Surface functionalization of virus-like particles by direct conjugation using azide-alkyne click chemistry
    • Patel K.G., Swartz J.R. Surface functionalization of virus-like particles by direct conjugation using azide-alkyne click chemistry. Bioconjug. Chem. 2011, 22:376-387.
    • (2011) Bioconjug. Chem. , vol.22 , pp. 376-387
    • Patel, K.G.1    Swartz, J.R.2
  • 171
    • 58349083892 scopus 로고    scopus 로고
    • Chemical modification of viruses and virus-like particles
    • Strable E., Finn M.G. Chemical modification of viruses and virus-like particles. Curr. Top. Microbiol. Immunol. 2009, 327:1-21.
    • (2009) Curr. Top. Microbiol. Immunol. , vol.327 , pp. 1-21
    • Strable, E.1    Finn, M.G.2
  • 174
    • 1542358952 scopus 로고    scopus 로고
    • Human papillomavirus vaccines and prevention of cervical cancer
    • Jansen K.U., Shaw A.R. Human papillomavirus vaccines and prevention of cervical cancer. Annu. Rev. Med. 2004, 55:319-331.
    • (2004) Annu. Rev. Med. , vol.55 , pp. 319-331
    • Jansen, K.U.1    Shaw, A.R.2
  • 175
    • 33747892383 scopus 로고    scopus 로고
    • Chapter 12: Prophylactic HPV vaccines: underlying mechanisms
    • (S3)
    • Stanley M., Lowy D.R., Frazer I. Chapter 12: Prophylactic HPV vaccines: underlying mechanisms. Vaccine 2006, 24(Suppl. 3):106-113. (S3).
    • (2006) Vaccine , vol.24 , pp. 106-113
    • Stanley, M.1    Lowy, D.R.2    Frazer, I.3
  • 176
    • 9244234954 scopus 로고    scopus 로고
    • Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs
    • Felnerova D., Viret J.F., Gluck R., Moser C. Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs. Curr. Opin. Biotechnol. 2004, 15:518-529.
    • (2004) Curr. Opin. Biotechnol. , vol.15 , pp. 518-529
    • Felnerova, D.1    Viret, J.F.2    Gluck, R.3    Moser, C.4
  • 177
    • 0026808892 scopus 로고
    • Immunopotentiating reconstituted influenza virosomes (IRIVs) and other adjuvants for improved presentation of small antigens
    • Gluck R. Immunopotentiating reconstituted influenza virosomes (IRIVs) and other adjuvants for improved presentation of small antigens. Vaccine 1992, 10:915-919.
    • (1992) Vaccine , vol.10 , pp. 915-919
    • Gluck, R.1
  • 178
    • 0028244249 scopus 로고
    • Immunogenicity of new virosome influenza vaccine in elderly people
    • Gluck R., Mischler R., Finkel B., Que J.U., Scarpa B., Cryz S.J. Immunogenicity of new virosome influenza vaccine in elderly people. Lancet 1994, 344:160-163.
    • (1994) Lancet , vol.344 , pp. 160-163
    • Gluck, R.1    Mischler, R.2    Finkel, B.3    Que, J.U.4    Scarpa, B.5    Cryz, S.J.6
  • 179
    • 0037146955 scopus 로고    scopus 로고
    • Inflexal V a trivalent virosome subunit influenza vaccine: production
    • Mischler R., Metcalfe I.C. Inflexal V a trivalent virosome subunit influenza vaccine: production. Vaccine 2002, 20(Suppl. 5):B17-B23.
    • (2002) Vaccine , vol.20 , pp. B17-B23
    • Mischler, R.1    Metcalfe, I.C.2
  • 180
    • 0034014999 scopus 로고    scopus 로고
    • IRIV-adjuvanted hepatitis A vaccine: in vivo absorption and biophysical characterization
    • Zurbriggen R., Novak-Hofer I., Seelig A., Gluck R. IRIV-adjuvanted hepatitis A vaccine: in vivo absorption and biophysical characterization. Prog. Lipid Res. 2000, 39:3-18.
    • (2000) Prog. Lipid Res. , vol.39 , pp. 3-18
    • Zurbriggen, R.1    Novak-Hofer, I.2    Seelig, A.3    Gluck, R.4
  • 182
    • 84907859073 scopus 로고    scopus 로고
    • Overcoming barriers in the mucosal delivery of virus-like particle-based vaccines
    • Herbst-Kralovetz M.M. Overcoming barriers in the mucosal delivery of virus-like particle-based vaccines. Ther. Deliv. 2014, 5:741-744.
    • (2014) Ther. Deliv. , vol.5 , pp. 741-744
    • Herbst-Kralovetz, M.M.1
  • 183
    • 35348998498 scopus 로고    scopus 로고
    • Influenza virosomes as a combined vaccine carrier and adjuvant system for prophylactic and therapeutic immunizations
    • Moser C., Amacker M., Kammer A.R., Rasi S., Westerfeld N., Zurbriggen R. Influenza virosomes as a combined vaccine carrier and adjuvant system for prophylactic and therapeutic immunizations. Expert Rev. Vaccines 2007, 6:711-721.
    • (2007) Expert Rev. Vaccines , vol.6 , pp. 711-721
    • Moser, C.1    Amacker, M.2    Kammer, A.R.3    Rasi, S.4    Westerfeld, N.5    Zurbriggen, R.6
  • 184
    • 84896903153 scopus 로고    scopus 로고
    • TLR7 and 9 agonists are highly effective mucosal adjuvants for norovirus virus-like particle vaccines
    • Hjelm B.E., Kilbourne J., Herbst-Kralovetz M.M. TLR7 and 9 agonists are highly effective mucosal adjuvants for norovirus virus-like particle vaccines. Hum. Vaccines Immunother. 2014, 10:410-416.
    • (2014) Hum. Vaccines Immunother. , vol.10 , pp. 410-416
    • Hjelm, B.E.1    Kilbourne, J.2    Herbst-Kralovetz, M.M.3
  • 185
    • 84864340558 scopus 로고    scopus 로고
    • Intranasal vaccination with murabutide enhances humoral and mucosal immune responses to a virus-like particle vaccine
    • Jackson E.M., Herbst-Kralovetz M.M. Intranasal vaccination with murabutide enhances humoral and mucosal immune responses to a virus-like particle vaccine. PLoS ONE 2012, 7:e41529.
    • (2012) PLoS ONE , vol.7 , pp. e41529
    • Jackson, E.M.1    Herbst-Kralovetz, M.M.2
  • 186
    • 33751253462 scopus 로고    scopus 로고
    • Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach
    • des Rieux A., Fievez V., Garinot M., Schneider Y.J., Preat V. Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach. J. Control. Release 2006, 116:1-27.
    • (2006) J. Control. Release , vol.116 , pp. 1-27
    • des Rieux, A.1    Fievez, V.2    Garinot, M.3    Schneider, Y.J.4    Preat, V.5
  • 187
    • 84859719708 scopus 로고    scopus 로고
    • Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers
    • Ensign L.M., Cone R., Hanes J. Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers. Adv. Drug Deliv. Rev. 2012, 64:557-570.
    • (2012) Adv. Drug Deliv. Rev. , vol.64 , pp. 557-570
    • Ensign, L.M.1    Cone, R.2    Hanes, J.3
  • 189
    • 0034125081 scopus 로고    scopus 로고
    • Immunological concepts of vaccine adjuvant activity
    • Schijns V.E. Immunological concepts of vaccine adjuvant activity. Curr. Opin. Immunol. 2000, 12:456-463.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 456-463
    • Schijns, V.E.1
  • 190
    • 0034806367 scopus 로고    scopus 로고
    • Microparticle vaccine approaches to stimulate mucosal immunisation
    • Brayden D.J., Baird A.W. Microparticle vaccine approaches to stimulate mucosal immunisation. Microbes Infect. 2001, 3:867-876.
    • (2001) Microbes Infect. , vol.3 , pp. 867-876
    • Brayden, D.J.1    Baird, A.W.2
  • 191
    • 76249115874 scopus 로고    scopus 로고
    • Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses
    • Lai S.K., Wang Y.Y., Hida K., Cone R., Hanes J. Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:598-603.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 598-603
    • Lai, S.K.1    Wang, Y.Y.2    Hida, K.3    Cone, R.4    Hanes, J.5
  • 193
    • 0034580371 scopus 로고    scopus 로고
    • The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices
    • Jain R.A. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 2000, 21:2475-2490.
    • (2000) Biomaterials , vol.21 , pp. 2475-2490
    • Jain, R.A.1
  • 194
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • Shive M.S., Anderson J.M. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv. Drug Deliv. Rev. 1997, 28:5-24.
    • (1997) Adv. Drug Deliv. Rev. , vol.28 , pp. 5-24
    • Shive, M.S.1    Anderson, J.M.2
  • 195
    • 66249134291 scopus 로고    scopus 로고
    • Biodegradable meshes printed with extracellular matrix proteins support micropatterned hepatocyte cultures
    • Woodrow K.A., Wood M.J., Saucier-Sawyer J.K., Solbrig C., Saltzman W.M. Biodegradable meshes printed with extracellular matrix proteins support micropatterned hepatocyte cultures. Tissue Eng. Part A 2009, 15:1169-1179.
    • (2009) Tissue Eng. Part A , vol.15 , pp. 1169-1179
    • Woodrow, K.A.1    Wood, M.J.2    Saucier-Sawyer, J.K.3    Solbrig, C.4    Saltzman, W.M.5
  • 196
    • 0034601281 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake?
    • Jung T., Kamm W., Breitenbach A., Kaiserling E., Xiao J.X., Kissel T. Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake?. Eur. J. Pharm. Biopharm. 2000, 50:147-160.
    • (2000) Eur. J. Pharm. Biopharm. , vol.50 , pp. 147-160
    • Jung, T.1    Kamm, W.2    Breitenbach, A.3    Kaiserling, E.4    Xiao, J.X.5    Kissel, T.6
  • 197
    • 77954902656 scopus 로고    scopus 로고
    • Intranasal M cell uptake of nanoparticles is independently influenced by targeting ligands and buffer ionic strength
    • Rajapaksa T.E., Bennett K.M., Hamer M., Lytle C., Rodgers V.G., Lo D.D. Intranasal M cell uptake of nanoparticles is independently influenced by targeting ligands and buffer ionic strength. J. Biol. Chem. 2010, 285:23739-23746.
    • (2010) J. Biol. Chem. , vol.285 , pp. 23739-23746
    • Rajapaksa, T.E.1    Bennett, K.M.2    Hamer, M.3    Lytle, C.4    Rodgers, V.G.5    Lo, D.D.6
  • 199
    • 84902277294 scopus 로고    scopus 로고
    • Cellulose acetate phthalate microparticles containing Vibrio cholerae: steps toward an oral cholera vaccine
    • Pastor M., Esquisabel A., Marquinez I., Talavera A., Pedraz J.L. Cellulose acetate phthalate microparticles containing Vibrio cholerae: steps toward an oral cholera vaccine. J. Drug Target. 2014, 22:478-487.
    • (2014) J. Drug Target. , vol.22 , pp. 478-487
    • Pastor, M.1    Esquisabel, A.2    Marquinez, I.3    Talavera, A.4    Pedraz, J.L.5
  • 200
    • 0028916964 scopus 로고
    • Immune responses and protection against Bordetella pertussis infection after intranasal immunization of mice with filamentous haemagglutinin in solution or incorporated in biodegradable microparticles
    • Cahill E.S., O'Hagan D.T., Illum L., Barnard A., Mills K.H., Redhead K. Immune responses and protection against Bordetella pertussis infection after intranasal immunization of mice with filamentous haemagglutinin in solution or incorporated in biodegradable microparticles. Vaccine 1995, 13:455-462.
    • (1995) Vaccine , vol.13 , pp. 455-462
    • Cahill, E.S.1    O'Hagan, D.T.2    Illum, L.3    Barnard, A.4    Mills, K.H.5    Redhead, K.6
  • 202
    • 0030218606 scopus 로고    scopus 로고
    • Intranasal stimulation of long-lasting immunity against aerosol ricin challenge with ricin toxoid vaccine encapsulated in polymeric microspheres
    • Yan C., Rill W.L., Malli R., Hewetson J., Naseem H., Tammariello R., Kende M. Intranasal stimulation of long-lasting immunity against aerosol ricin challenge with ricin toxoid vaccine encapsulated in polymeric microspheres. Vaccine 1996, 14:1031-1038.
    • (1996) Vaccine , vol.14 , pp. 1031-1038
    • Yan, C.1    Rill, W.L.2    Malli, R.3    Hewetson, J.4    Naseem, H.5    Tammariello, R.6    Kende, M.7
  • 207
    • 2942627626 scopus 로고    scopus 로고
    • Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses
    • Seong S.Y., Matzinger P. Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat. Rev. Immunol. 2004, 4:469-478.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 469-478
    • Seong, S.Y.1    Matzinger, P.2
  • 210
    • 65449166078 scopus 로고    scopus 로고
    • Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists
    • Huang H., Ostroff G.R., Lee C.K., Wang J.P., Specht C.A., Levitz S.M. Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists. Infect. Immun. 2009, 77:1774-1781.
    • (2009) Infect. Immun. , vol.77 , pp. 1774-1781
    • Huang, H.1    Ostroff, G.R.2    Lee, C.K.3    Wang, J.P.4    Specht, C.A.5    Levitz, S.M.6
  • 211
    • 42949139254 scopus 로고    scopus 로고
    • Characterization of multilayered nanoparticles encapsulated in yeast cell wall particles for DNA delivery
    • Soto E.R., Ostroff G.R. Characterization of multilayered nanoparticles encapsulated in yeast cell wall particles for DNA delivery. Bioconjug. Chem. 2008, 19:840-848.
    • (2008) Bioconjug. Chem. , vol.19 , pp. 840-848
    • Soto, E.R.1    Ostroff, G.R.2
  • 212
    • 0035817818 scopus 로고    scopus 로고
    • Immune recognition. A new receptor for beta-glucans
    • Brown G.D., Gordon S. Immune recognition. A new receptor for beta-glucans. Nature 2001, 413:36-37.
    • (2001) Nature , vol.413 , pp. 36-37
    • Brown, G.D.1    Gordon, S.2
  • 213
    • 84940960915 scopus 로고    scopus 로고
    • http://www.accessdata.fda.gov/scripts/fcn/gras_notices/grn000239.PDF.
  • 214
    • 84898470940 scopus 로고    scopus 로고
    • A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling beta-glucan microparticles
    • De Jesus M., Ostroff G.R., Levitz S.M., Bartling T.R., Mantis N.J. A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling beta-glucan microparticles. PLoS ONE 2014, 9:e91002.
    • (2014) PLoS ONE , vol.9 , pp. e91002
    • De Jesus, M.1    Ostroff, G.R.2    Levitz, S.M.3    Bartling, T.R.4    Mantis, N.J.5
  • 215
    • 0025731293 scopus 로고
    • Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres
    • Cohen S., Yoshioka T., Lucarelli M., Hwang L.H., Langer R. Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres. Pharm. Res. 1991, 8:713-720.
    • (1991) Pharm. Res. , vol.8 , pp. 713-720
    • Cohen, S.1    Yoshioka, T.2    Lucarelli, M.3    Hwang, L.H.4    Langer, R.5
  • 216
    • 0035859983 scopus 로고    scopus 로고
    • Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A
    • De Campos A.M., Sanchez A., Alonso M.J. Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A. Int. J. Pharm. 2001, 224:159-168.
    • (2001) Int. J. Pharm. , vol.224 , pp. 159-168
    • De Campos, A.M.1    Sanchez, A.2    Alonso, M.J.3
  • 217
    • 0017536083 scopus 로고
    • Degradation rates of oral resorbable implants (polylactates and polyglycolates): rate modification with changes in PLA/PGA copolymer ratios
    • Miller R.A., Brady J.M., Cutright D.E. Degradation rates of oral resorbable implants (polylactates and polyglycolates): rate modification with changes in PLA/PGA copolymer ratios. J. Biomed. Mater. Res. 1977, 11:711-719.
    • (1977) J. Biomed. Mater. Res. , vol.11 , pp. 711-719
    • Miller, R.A.1    Brady, J.M.2    Cutright, D.E.3
  • 218
    • 84875259359 scopus 로고    scopus 로고
    • Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-gamma T cell responses in humans
    • Peters W., Brandl J.R., Lindbloom J.D., Martinez C.J., Scallan C.D., Trager G.R., Tingley D.W., Kabongo M.L., Tucker S.N. Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-gamma T cell responses in humans. Vaccine 2013, 31:1752-1758.
    • (2013) Vaccine , vol.31 , pp. 1752-1758
    • Peters, W.1    Brandl, J.R.2    Lindbloom, J.D.3    Martinez, C.J.4    Scallan, C.D.5    Trager, G.R.6    Tingley, D.W.7    Kabongo, M.L.8    Tucker, S.N.9
  • 224
    • 26444444081 scopus 로고    scopus 로고
    • Development of an enteric-coated, layered multi-particulate formulation for ileal delivery of viable recombinant Lactococcus lactis
    • Huyghebaert N., Vermeire A., Rottiers P., Remaut E., Remon J.P. Development of an enteric-coated, layered multi-particulate formulation for ileal delivery of viable recombinant Lactococcus lactis. Eur. J. Pharm. Biopharm. 2005, 61:134-141.
    • (2005) Eur. J. Pharm. Biopharm. , vol.61 , pp. 134-141
    • Huyghebaert, N.1    Vermeire, A.2    Rottiers, P.3    Remaut, E.4    Remon, J.P.5
  • 226
    • 0027259027 scopus 로고
    • Stability of liposomes in vitro and their uptake by rat Peyer's patches following oral administration
    • Aramaki Y., Tomizawa H., Hara T., Yachi K., Kikuchi H., Tsuchiya S. Stability of liposomes in vitro and their uptake by rat Peyer's patches following oral administration. Pharm. Res. 1993, 10:1228-1231.
    • (1993) Pharm. Res. , vol.10 , pp. 1228-1231
    • Aramaki, Y.1    Tomizawa, H.2    Hara, T.3    Yachi, K.4    Kikuchi, H.5    Tsuchiya, S.6
  • 227
    • 0031307162 scopus 로고    scopus 로고
    • Application of liposomes for development of oral vaccines: study of in vitro stability of liposomes and antibody response to antigen associated with liposomes after oral immunization
    • Han M., Watarai S., Kobayashi K., Yasuda T. Application of liposomes for development of oral vaccines: study of in vitro stability of liposomes and antibody response to antigen associated with liposomes after oral immunization. J. Vet. Med. Sci. 1997, 59:1109-1114.
    • (1997) J. Vet. Med. Sci. , vol.59 , pp. 1109-1114
    • Han, M.1    Watarai, S.2    Kobayashi, K.3    Yasuda, T.4
  • 228
    • 0033575434 scopus 로고    scopus 로고
    • PLG microparticles stabilised using enteric coating polymers as oral vaccine delivery systems
    • Delgado A., Lavelle E.C., Hartshorne M., Davis S.S. PLG microparticles stabilised using enteric coating polymers as oral vaccine delivery systems. Vaccine 1999, 17:2927-2938.
    • (1999) Vaccine , vol.17 , pp. 2927-2938
    • Delgado, A.1    Lavelle, E.C.2    Hartshorne, M.3    Davis, S.S.4
  • 229
    • 4043088519 scopus 로고    scopus 로고
    • Anatomical and cellular basis of immunity and tolerance in the intestine
    • Mowat A.M., Millington O.R., Chirdo F.G. Anatomical and cellular basis of immunity and tolerance in the intestine. J. Pediatr. Gastroenterol. Nutr. 2004, 39(Suppl. 3):S723-S724.
    • (2004) J. Pediatr. Gastroenterol. Nutr. , vol.39 , pp. S723-S724
    • Mowat, A.M.1    Millington, O.R.2    Chirdo, F.G.3
  • 230
    • 0033949608 scopus 로고    scopus 로고
    • New insights into oral tolerance
    • Whitacre C.C. New insights into oral tolerance. Gastroenterology 2000, 119:260-263.
    • (2000) Gastroenterology , vol.119 , pp. 260-263
    • Whitacre, C.C.1
  • 232
    • 0032033578 scopus 로고    scopus 로고
    • Ulex europaeus 1 lectin targets microspheres to mouse Peyer's patch M-cells in vivo
    • Foster N., Clark M.A., Jepson M.A., Hirst B.H. Ulex europaeus 1 lectin targets microspheres to mouse Peyer's patch M-cells in vivo. Vaccine 1998, 16:536-541.
    • (1998) Vaccine , vol.16 , pp. 536-541
    • Foster, N.1    Clark, M.A.2    Jepson, M.A.3    Hirst, B.H.4
  • 233
    • 0034797445 scopus 로고    scopus 로고
    • Targeted delivery of drugs to the gastrointestinal tract
    • Lavelle E.C. Targeted delivery of drugs to the gastrointestinal tract. Crit. Rev. Ther. Drug Carrier Syst. 2001, 18:341-386.
    • (2001) Crit. Rev. Ther. Drug Carrier Syst. , vol.18 , pp. 341-386
    • Lavelle, E.C.1
  • 235
    • 27744548806 scopus 로고    scopus 로고
    • Enhanced mucosal and systemic immune response with intranasal immunization of mice with HIV peptides entrapped in PLG microparticles in combination with Ulex Europaeus-I lectin as M cell target
    • Manocha M., Pal P.C., Chitralekha K.T., Thomas B.E., Tripathi V., Gupta S.D., Paranjape R., Kulkarni S., Rao D.N. Enhanced mucosal and systemic immune response with intranasal immunization of mice with HIV peptides entrapped in PLG microparticles in combination with Ulex Europaeus-I lectin as M cell target. Vaccine 2005, 23:5599-5617.
    • (2005) Vaccine , vol.23 , pp. 5599-5617
    • Manocha, M.1    Pal, P.C.2    Chitralekha, K.T.3    Thomas, B.E.4    Tripathi, V.5    Gupta, S.D.6    Paranjape, R.7    Kulkarni, S.8    Rao, D.N.9
  • 238
    • 0025908008 scopus 로고
    • Monoclonal antibody-directed targeting of fluorescent polystyrene microspheres to Peyer's patch M cells
    • Pappo J., Ermak T.H., Steger H.J. Monoclonal antibody-directed targeting of fluorescent polystyrene microspheres to Peyer's patch M cells. Immunology 1991, 73:277-280.
    • (1991) Immunology , vol.73 , pp. 277-280
    • Pappo, J.1    Ermak, T.H.2    Steger, H.J.3
  • 239
    • 0029063450 scopus 로고
    • Mucosal IgA response to rectally administered antigen formulated in IgA-coated liposomes
    • Zhou F., Kraehenbuhl J.P., Neutra M.R. Mucosal IgA response to rectally administered antigen formulated in IgA-coated liposomes. Vaccine 1995, 13:637-644.
    • (1995) Vaccine , vol.13 , pp. 637-644
    • Zhou, F.1    Kraehenbuhl, J.P.2    Neutra, M.R.3
  • 240
    • 0031939292 scopus 로고    scopus 로고
    • Utilizing bacterial mechanisms of epithelial cell entry: invasin-induced oral uptake of latex nanoparticles
    • Hussain N., Florence A.T. Utilizing bacterial mechanisms of epithelial cell entry: invasin-induced oral uptake of latex nanoparticles. Pharm. Res. 1998, 15:153-156.
    • (1998) Pharm. Res. , vol.15 , pp. 153-156
    • Hussain, N.1    Florence, A.T.2
  • 242
    • 0015619335 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution
    • Steinman R.M., Cohn Z.A. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med. 1973, 137:1142-1162.
    • (1973) J. Exp. Med. , vol.137 , pp. 1142-1162
    • Steinman, R.M.1    Cohn, Z.A.2
  • 243
    • 0018966159 scopus 로고
    • Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes
    • Nussenzweig M.C., Steinman R.M., Gutchinov B., Cohn Z.A. Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes. J. Exp. Med. 1980, 152:1070-1084.
    • (1980) J. Exp. Med. , vol.152 , pp. 1070-1084
    • Nussenzweig, M.C.1    Steinman, R.M.2    Gutchinov, B.3    Cohn, Z.A.4
  • 244
    • 34748886192 scopus 로고    scopus 로고
    • Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting
    • Tacken P.J., de Vries I.J., Torensma R., Figdor C.G. Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat. Rev. Immunol. 2007, 7:790-802.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 790-802
    • Tacken, P.J.1    de Vries, I.J.2    Torensma, R.3    Figdor, C.G.4
  • 245
    • 77954759581 scopus 로고    scopus 로고
    • Recognition of secretory IgA by DC-SIGN: implications for immune surveillance in the intestine
    • Baumann J., Park C.G., Mantis N.J. Recognition of secretory IgA by DC-SIGN: implications for immune surveillance in the intestine. Immunol. Lett. 2010, 131:59-66.
    • (2010) Immunol. Lett. , vol.131 , pp. 59-66
    • Baumann, J.1    Park, C.G.2    Mantis, N.J.3
  • 247
    • 34247877512 scopus 로고    scopus 로고
    • Mucosal dendritic cells
    • Iwasaki A. Mucosal dendritic cells. Annu. Rev. Immunol. 2007, 25:381-418.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 381-418
    • Iwasaki, A.1
  • 248
    • 26644454810 scopus 로고    scopus 로고
    • The basics and underlying mechanisms of mucoadhesion
    • Smart J.D. The basics and underlying mechanisms of mucoadhesion. Adv. Drug Deliv. Rev. 2005, 57:1556-1568.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 1556-1568
    • Smart, J.D.1
  • 252
    • 84940955499 scopus 로고    scopus 로고
    • Kazunari A., Kiyono H., Yoshikazu Y., Tomonori N. Mucosal vaccine using cationic +nanogel 2010, (https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2010050578&recNum=212&docAn=JP2009068647&queryString=%28%28et/adjuvant%29%20or%20%28ABE/adjuvant%29%29%20AND%20%28%28ET/vaccine%29%20or%20%28ET/immunogenic%29%20or%20%28ET/antigen%29%20OR%20%28ABE/vaccine%29%20or%20%28ABE/immunogenic%29%20or%20%28ABE/antigen%29%29&maxRec=1307).
    • (2010) Mucosal vaccine using cationic +nanogel
    • Kazunari, A.1    Kiyono, H.2    Yoshikazu, Y.3    Tomonori, N.4
  • 254
    • 0034668160 scopus 로고    scopus 로고
    • Characterization of mucoadhesive microspheres for the induction of mucosal and systemic immune responses
    • Kunisawa J., Okudaira A., Tsutusmi Y., Takahashi I., Nakanishi T., Kiyono H., Mayumi T. Characterization of mucoadhesive microspheres for the induction of mucosal and systemic immune responses. Vaccine 2000, 19:589-594.
    • (2000) Vaccine , vol.19 , pp. 589-594
    • Kunisawa, J.1    Okudaira, A.2    Tsutusmi, Y.3    Takahashi, I.4    Nakanishi, T.5    Kiyono, H.6    Mayumi, T.7
  • 256
    • 0035478758 scopus 로고    scopus 로고
    • Chitosan and its derivatives as intestinal absorption enhancers
    • Thanou M., Verhoef J.C., Junginger H.E. Chitosan and its derivatives as intestinal absorption enhancers. Adv. Drug Deliv. Rev. 2001, 50(Suppl. 1):S91-S101.
    • (2001) Adv. Drug Deliv. Rev. , vol.50 , pp. S91-S101
    • Thanou, M.1    Verhoef, J.C.2    Junginger, H.E.3
  • 258
    • 84904403397 scopus 로고    scopus 로고
    • When, how, and where can oral cholera vaccines be used to interrupt cholera outbreaks?
    • Clemens J., Holmgren J. When, how, and where can oral cholera vaccines be used to interrupt cholera outbreaks?. Curr. Top. Microbiol. Immunol. 2014, 379:231-258.
    • (2014) Curr. Top. Microbiol. Immunol. , vol.379 , pp. 231-258
    • Clemens, J.1    Holmgren, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.