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Volumn 34, Issue 2, 2011, Pages 269-280

Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges

(19)  Bomsel, Morgane a,b,c   Tudor, Daniela a,b,c   Drillet, Anne Sophie a,b,c   Alfsen, Annette a,b,c   Ganor, Yonatan a,b,c   Roger, Marie Gaëlle d   Mouz, Nicolas d   Amacker, Mario e   Chalifour, Anick f   Diomede, Lorenzo g   Devillier, Gilles h   Cong, Zhe i   Wei, Qiang i   Gao, Hong i   Qin, Chuan i   Yang, Gui Bo j   Zurbriggen, Rinaldo e,k   Lopalco, Lucia g   Fleury, Sylvain f  

a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; NEUTRALIZING ANTIBODY; PLACEBO; VIROSOME; VIRUS ANTIBODY;

EID: 79951754740     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2011.01.015     Document Type: Article
Times cited : (260)

References (56)
  • 1
    • 0037067741 scopus 로고    scopus 로고
    • HIV-1 gp41 envelope residues 650-685 exposed on native virus act as a lectin to bind epithelial cell galactosyl ceramide
    • Alfsen A., Bomsel M. HIV-1 gp41 envelope residues 650-685 exposed on native virus act as a lectin to bind epithelial cell galactosyl ceramide. J. Biol. Chem. 2002, 277:25649-25659.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25649-25659
    • Alfsen, A.1    Bomsel, M.2
  • 2
    • 0035873475 scopus 로고    scopus 로고
    • Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1
    • Alfsen A., Iniguez P., Bouguyon E., Bomsel M. Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1. J. Immunol. 2001, 166:6257-6265.
    • (2001) J. Immunol. , vol.166 , pp. 6257-6265
    • Alfsen, A.1    Iniguez, P.2    Bouguyon, E.3    Bomsel, M.4
  • 5
    • 0031023496 scopus 로고    scopus 로고
    • Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier
    • Bomsel M. Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier. Nat. Med. 1997, 3:42-47.
    • (1997) Nat. Med. , vol.3 , pp. 42-47
    • Bomsel, M.1
  • 6
    • 18844470061 scopus 로고    scopus 로고
    • Intracellular neutralization of HIV transcytosis across tight epithelial barriers by anti-HIV envelope protein dIgA or IgM
    • Bomsel M., Heyman M., Hocini H., Lagaye S., Belec L., Dupont C., Desgranges C. Intracellular neutralization of HIV transcytosis across tight epithelial barriers by anti-HIV envelope protein dIgA or IgM. Immunity 1998, 9:277-287.
    • (1998) Immunity , vol.9 , pp. 277-287
    • Bomsel, M.1    Heyman, M.2    Hocini, H.3    Lagaye, S.4    Belec, L.5    Dupont, C.6    Desgranges, C.7
  • 7
    • 33845496088 scopus 로고    scopus 로고
    • Natural mucosal antibodies reactive with first extracellular loop of CCR5 inhibit HIV-1 transport across human epithelial cells
    • Bomsel M., Pastori C., Tudor D., Alberti C., Garcia S., Ferrari D., Lazzarin A., Lopalco L. Natural mucosal antibodies reactive with first extracellular loop of CCR5 inhibit HIV-1 transport across human epithelial cells. AIDS 2007, 21:13-22.
    • (2007) AIDS , vol.21 , pp. 13-22
    • Bomsel, M.1    Pastori, C.2    Tudor, D.3    Alberti, C.4    Garcia, S.5    Ferrari, D.6    Lazzarin, A.7    Lopalco, L.8
  • 8
    • 0033017269 scopus 로고    scopus 로고
    • Diversity of antibody-mediated immunity at the mucosal barrier
    • Bouvet J.P., Fischetti V.A. Diversity of antibody-mediated immunity at the mucosal barrier. Infect. Immun. 1999, 67:2687-2691.
    • (1999) Infect. Immun. , vol.67 , pp. 2687-2691
    • Bouvet, J.P.1    Fischetti, V.A.2
  • 9
    • 0036533644 scopus 로고    scopus 로고
    • Stimulation of local antibody production: Parenteral or mucosal vaccination?
    • Bouvet J.P., Decroix N., Pamonsinlapatham P. Stimulation of local antibody production: Parenteral or mucosal vaccination?. Trends Immunol. 2002, 23:209-213.
    • (2002) Trends Immunol. , vol.23 , pp. 209-213
    • Bouvet, J.P.1    Decroix, N.2    Pamonsinlapatham, P.3
  • 10
    • 70450064812 scopus 로고    scopus 로고
    • Mucosal immunity: Induction, dissemination, and effector functions
    • Brandtzaeg P. Mucosal immunity: Induction, dissemination, and effector functions. Scand. J. Immunol. 2009, 70:505-515.
    • (2009) Scand. J. Immunol. , vol.70 , pp. 505-515
    • Brandtzaeg, P.1
  • 12
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
    • Step Study Protocol Team
    • Buchbinder S.P., Mehrotra D.V., Duerr A., Fitzgerald D.W., Mogg R., Li D., Gilbert P.B., Lama J.R., Marmor M., Del Rio C., et al. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 2008, 372:1881-1893. Step Study Protocol Team.
    • (2008) Lancet , vol.372 , pp. 1881-1893
    • Buchbinder, S.P.1    Mehrotra, D.V.2    Duerr, A.3    Fitzgerald, D.W.4    Mogg, R.5    Li, D.6    Gilbert, P.B.7    Lama, J.R.8    Marmor, M.9    Del Rio, C.10
  • 13
    • 33845956481 scopus 로고    scopus 로고
    • Roundtrip ticket for secretory IgA: Role in mucosal homeostasis?
    • Corthésy B. Roundtrip ticket for secretory IgA: Role in mucosal homeostasis?. J. Immunol. 2007, 178:27-32.
    • (2007) J. Immunol. , vol.178 , pp. 27-32
    • Corthésy, B.1
  • 14
    • 57349170319 scopus 로고    scopus 로고
    • Both lipid environment and pH are critical for determining physiological solution structure of 3-D-conserved epitopes of the HIV-1 gp41-MPER peptide P1
    • Coutant J., Yu H., Clément M.J., Alfsen A., Toma F., Curmi P.A., Bomsel M. Both lipid environment and pH are critical for determining physiological solution structure of 3-D-conserved epitopes of the HIV-1 gp41-MPER peptide P1. FASEB J. 2008, 22:4338-4351.
    • (2008) FASEB J. , vol.22 , pp. 4338-4351
    • Coutant, J.1    Yu, H.2    Clément, M.J.3    Alfsen, A.4    Toma, F.5    Curmi, P.A.6    Bomsel, M.7
  • 15
    • 0036237286 scopus 로고    scopus 로고
    • Comprehensive screening for human immunodeficiency virus type 1 subtype-specific CD8 cytotoxic T lymphocytes and definition of degenerate epitopes restricted by HLA-A0207 and -C(W)0304 alleles
    • Currier J.R., deSouza M., Chanbancherd P., Bernstein W., Birx D.L., Cox J.H. Comprehensive screening for human immunodeficiency virus type 1 subtype-specific CD8 cytotoxic T lymphocytes and definition of degenerate epitopes restricted by HLA-A0207 and -C(W)0304 alleles. J. Virol. 2002, 76:4971-4986.
    • (2002) J. Virol. , vol.76 , pp. 4971-4986
    • Currier, J.R.1    deSouza, M.2    Chanbancherd, P.3    Bernstein, W.4    Birx, D.L.5    Cox, J.H.6
  • 17
    • 60949098815 scopus 로고    scopus 로고
    • Mucosal immunity and protection against HIV/SIV infection: Strategies and challenges for vaccine design
    • Demberg T., Robert-Guroff M. Mucosal immunity and protection against HIV/SIV infection: Strategies and challenges for vaccine design. Int. Rev. Immunol. 2009, 28:20-48.
    • (2009) Int. Rev. Immunol. , vol.28 , pp. 20-48
    • Demberg, T.1    Robert-Guroff, M.2
  • 19
    • 0034622980 scopus 로고    scopus 로고
    • Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate
    • Devito C., Hinkula J., Kaul R., Lopalco L., Bwayo J.J., Plummer F., Clerici M., Broliden K. Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate. AIDS 2000, 14:1917-1920.
    • (2000) AIDS , vol.14 , pp. 1917-1920
    • Devito, C.1    Hinkula, J.2    Kaul, R.3    Lopalco, L.4    Bwayo, J.J.5    Plummer, F.6    Clerici, M.7    Broliden, K.8
  • 21
    • 79951774122 scopus 로고    scopus 로고
    • Setting of methods for analysis of mucosal antibodies in seminal and vaginal fluids of HIV seropositive subjects from Cambodian and Italian cohorts
    • Donadoni C., Bisighini C., Scotti L., Diomede L., Ngyen M., Nouhin J., DeSantis L., Zambon A., Ferrari D., Gallotta G., et al. Setting of methods for analysis of mucosal antibodies in seminal and vaginal fluids of HIV seropositive subjects from Cambodian and Italian cohorts. PLoS ONE 2010, 5:e9920.
    • (2010) PLoS ONE , vol.5
    • Donadoni, C.1    Bisighini, C.2    Scotti, L.3    Diomede, L.4    Ngyen, M.5    Nouhin, J.6    DeSantis, L.7    Zambon, A.8    Ferrari, D.9    Gallotta, G.10
  • 22
    • 69549103041 scopus 로고    scopus 로고
    • Fc receptor-mediated antiviral antibodies
    • Forthal D.N., Moog C. Fc receptor-mediated antiviral antibodies. Curr Opin HIV AIDS 2009, 4:388-393.
    • (2009) Curr Opin HIV AIDS , vol.4 , pp. 388-393
    • Forthal, D.N.1    Moog, C.2
  • 24
    • 0035132287 scopus 로고    scopus 로고
    • Mucosal transmission and induction of simian AIDS by CCR5-specific simian/human immunodeficiency virus SHIV(SF162P3)
    • Harouse J.M., Gettie A., Eshetu T., Tan R.C., Bohm R., Blanchard J., Baskin G., Cheng-Mayer C. Mucosal transmission and induction of simian AIDS by CCR5-specific simian/human immunodeficiency virus SHIV(SF162P3). J. Virol. 2001, 75:1990-1995.
    • (2001) J. Virol. , vol.75 , pp. 1990-1995
    • Harouse, J.M.1    Gettie, A.2    Eshetu, T.3    Tan, R.C.4    Bohm, R.5    Blanchard, J.6    Baskin, G.7    Cheng-Mayer, C.8
  • 27
    • 73949154006 scopus 로고    scopus 로고
    • Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L
    • Hessell A.J., Rakasz E.G., Tehrani D.M., Huber M., Weisgrau K.L., Landucci G., Forthal D.N., Koff W.C., Poignard P., Watkins D.I., Burton D.R. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L. J. Virol. 2010, 84:1302-1313.
    • (2010) J. Virol. , vol.84 , pp. 1302-1313
    • Hessell, A.J.1    Rakasz, E.G.2    Tehrani, D.M.3    Huber, M.4    Weisgrau, K.L.5    Landucci, G.6    Forthal, D.N.7    Koff, W.C.8    Poignard, P.9    Watkins, D.I.10    Burton, D.R.11
  • 28
    • 44349159423 scopus 로고    scopus 로고
    • Setting the stage: Host invasion by HIV
    • Hladik F., McElrath M.J. Setting the stage: Host invasion by HIV. Nat. Rev. Immunol. 2008, 8:447-457.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 447-457
    • Hladik, F.1    McElrath, M.J.2
  • 29
    • 8544258110 scopus 로고    scopus 로고
    • The caveolin-1 binding domain of HIV-1 glycoprotein gp41 is an efficient B cell epitope vaccine candidate against virus infection
    • Hovanessian A.G., Briand J.P., Said E.A., Svab J., Ferris S., Dali H., Muller S., Desgranges C., Krust B. The caveolin-1 binding domain of HIV-1 glycoprotein gp41 is an efficient B cell epitope vaccine candidate against virus infection. Immunity 2004, 21:617-627.
    • (2004) Immunity , vol.21 , pp. 617-627
    • Hovanessian, A.G.1    Briand, J.P.2    Said, E.A.3    Svab, J.4    Ferris, S.5    Dali, H.6    Muller, S.7    Desgranges, C.8    Krust, B.9
  • 30
    • 34648837301 scopus 로고    scopus 로고
    • A new and versatile virosomal antigen delivery system to induce cellular and humoral immune responses
    • Kammer A.R., Amacker M., Rasi S., Westerfeld N., Gremion C., Neuhaus D., Zurbriggen R. A new and versatile virosomal antigen delivery system to induce cellular and humoral immune responses. Vaccine 2007, 25:7065-7074.
    • (2007) Vaccine , vol.25 , pp. 7065-7074
    • Kammer, A.R.1    Amacker, M.2    Rasi, S.3    Westerfeld, N.4    Gremion, C.5    Neuhaus, D.6    Zurbriggen, R.7
  • 31
    • 74549172907 scopus 로고    scopus 로고
    • Construction and characterization of a new simian/human immunodeficiency viruses clone carrying an env gene derived from a CRF07_BC strain
    • Li Y., Yang G.B., Chen Q.M., Liu Q., Meng Z.F., Geng Y.Q., Qiao W.T., Shao Y.M. Construction and characterization of a new simian/human immunodeficiency viruses clone carrying an env gene derived from a CRF07_BC strain. Chin. Med. J. (Engl.) 2009, 122:2874-2879.
    • (2009) Chin. Med. J. (Engl.) , vol.122 , pp. 2874-2879
    • Li, Y.1    Yang, G.B.2    Chen, Q.M.3    Liu, Q.4    Meng, Z.F.5    Geng, Y.Q.6    Qiao, W.T.7    Shao, Y.M.8
  • 34
    • 34247341369 scopus 로고    scopus 로고
    • Galactosyl ceramide expressed on dendritic cells can mediate HIV-1 transfer from monocyte derived dendritic cells to autologous T cells
    • Magérus-Chatinet A., Yu H., Garcia S., Ducloux E., Terris B., Bomsel M. Galactosyl ceramide expressed on dendritic cells can mediate HIV-1 transfer from monocyte derived dendritic cells to autologous T cells. Virology 2007, 362:67-74.
    • (2007) Virology , vol.362 , pp. 67-74
    • Magérus-Chatinet, A.1    Yu, H.2    Garcia, S.3    Ducloux, E.4    Terris, B.5    Bomsel, M.6
  • 35
    • 58949097921 scopus 로고    scopus 로고
    • The 'immunologic advantage' of HIV-exposed seronegative individuals
    • ESN Study Group
    • Miyazawa M., Lopalco L., Mazzotta F., Lo Caputo S., Veas F., Clerici M. The 'immunologic advantage' of HIV-exposed seronegative individuals. AIDS 2009, 23:161-175. ESN Study Group.
    • (2009) AIDS , vol.23 , pp. 161-175
    • Miyazawa, M.1    Lopalco, L.2    Mazzotta, F.3    Lo Caputo, S.4    Veas, F.5    Clerici, M.6
  • 36
    • 40849136223 scopus 로고    scopus 로고
    • The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: Dominant site of antibody neutralization and target for vaccine design
    • Montero M., van Houten N.E., Wang X., Scott J.K. The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: Dominant site of antibody neutralization and target for vaccine design. Microbiol. Mol. Biol. Rev. 2008, 72:54-84.
    • (2008) Microbiol. Mol. Biol. Rev. , vol.72 , pp. 54-84
    • Montero, M.1    van Houten, N.E.2    Wang, X.3    Scott, J.K.4
  • 37
    • 35348998498 scopus 로고    scopus 로고
    • Influenza virosomes as a combined vaccine carrier and adjuvant system for prophylactic and therapeutic immunizations
    • Moser C., Amacker M., Kammer A.R., Rasi S., Westerfeld N., Zurbriggen R. Influenza virosomes as a combined vaccine carrier and adjuvant system for prophylactic and therapeutic immunizations. Expert Rev. Vaccines 2007, 6:711-721.
    • (2007) Expert Rev. Vaccines , vol.6 , pp. 711-721
    • Moser, C.1    Amacker, M.2    Kammer, A.R.3    Rasi, S.4    Westerfeld, N.5    Zurbriggen, R.6
  • 40
    • 0036784572 scopus 로고    scopus 로고
    • Magnitude and frequency of cytotoxic T-lymphocyte responses: Identification of immunodominant regions of human immunodeficiency virus type 1 subtype C
    • Novitsky V., Cao H., Rybak N., Gilbert P., McLane M.F., Gaolekwe S., Peter T., Thior I., Ndung'u T., Marlink R., et al. Magnitude and frequency of cytotoxic T-lymphocyte responses: Identification of immunodominant regions of human immunodeficiency virus type 1 subtype C. J. Virol. 2002, 76:10155-10168.
    • (2002) J. Virol. , vol.76 , pp. 10155-10168
    • Novitsky, V.1    Cao, H.2    Rybak, N.3    Gilbert, P.4    McLane, M.F.5    Gaolekwe, S.6    Peter, T.7    Thior, I.8    Ndung'u, T.9    Marlink, R.10
  • 41
    • 0015621886 scopus 로고
    • Local antibody response to poliovaccine in the human female genital tract
    • Ogra P.L., Ogra S.S. Local antibody response to poliovaccine in the human female genital tract. J. Immunol. 1973, 110:1307-1311.
    • (1973) J. Immunol. , vol.110 , pp. 1307-1311
    • Ogra, P.L.1    Ogra, S.S.2
  • 42
    • 41949120129 scopus 로고    scopus 로고
    • Two amino acid substitutions within the first external loop of CCR5 induce human immunodeficiency virus-blocking antibodies in mice and chickens
    • Pastori C., Clivio A., Diomede L., Consonni R., De Mori G.M., Longhi R., Colombo G., Lopalco L. Two amino acid substitutions within the first external loop of CCR5 induce human immunodeficiency virus-blocking antibodies in mice and chickens. J. Virol. 2008, 82:4125-4134.
    • (2008) J. Virol. , vol.82 , pp. 4125-4134
    • Pastori, C.1    Clivio, A.2    Diomede, L.3    Consonni, R.4    De Mori, G.M.5    Longhi, R.6    Colombo, G.7    Lopalco, L.8
  • 44
    • 0034988648 scopus 로고    scopus 로고
    • AIDS: An immune response against the immune system. Role of a precise tridimensional molecular mimicry
    • Serres P.F. AIDS: An immune response against the immune system. Role of a precise tridimensional molecular mimicry. J. Autoimmun. 2001, 16:287-291.
    • (2001) J. Autoimmun. , vol.16 , pp. 287-291
    • Serres, P.F.1
  • 46
    • 0035701421 scopus 로고    scopus 로고
    • A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1
    • Stiegler G., Kunert R., Purtscher M., Wolbank S., Voglauer R., Steindl F., Katinger H. A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1. AIDS Res. Hum. Retroviruses 2001, 17:1757-1765.
    • (2001) AIDS Res. Hum. Retroviruses , vol.17 , pp. 1757-1765
    • Stiegler, G.1    Kunert, R.2    Purtscher, M.3    Wolbank, S.4    Voglauer, R.5    Steindl, F.6    Katinger, H.7
  • 47
    • 37849000389 scopus 로고    scopus 로고
    • HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
    • Sun Z.Y., Oh K.J., Kim M., Yu J., Brusic V., Song L., Qiao Z., Wang J.H., Wagner G., Reinherz E.L. HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane. Immunity 2008, 28:52-63.
    • (2008) Immunity , vol.28 , pp. 52-63
    • Sun, Z.Y.1    Oh, K.J.2    Kim, M.3    Yu, J.4    Brusic, V.5    Song, L.6    Qiao, Z.7    Wang, J.H.8    Wagner, G.9    Reinherz, E.L.10
  • 49
    • 69249086612 scopus 로고    scopus 로고
    • HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: An IgA gene and functional analysis
    • Tudor D., Derrien M., Diomede L., Drillet A.S., Houimel M., Moog C., Reynes J.M., Lopalco L., Bomsel M. HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: An IgA gene and functional analysis. Mucosal Immunol. 2009, 2:412-426.
    • (2009) Mucosal Immunol. , vol.2 , pp. 412-426
    • Tudor, D.1    Derrien, M.2    Diomede, L.3    Drillet, A.S.4    Houimel, M.5    Moog, C.6    Reynes, J.M.7    Lopalco, L.8    Bomsel, M.9
  • 50
    • 33747892494 scopus 로고    scopus 로고
    • Current efforts on generation of optimal immune responses against HIV through mucosal immunisations
    • Vajdy M. Current efforts on generation of optimal immune responses against HIV through mucosal immunisations. Drugs R D. 2006, 7:267-288.
    • (2006) Drugs R D. , vol.7 , pp. 267-288
    • Vajdy, M.1
  • 52
    • 73349125483 scopus 로고    scopus 로고
    • Influenza vaccS200ines: The virosome concept
    • Wilschut J. Influenza vaccS200ines: The virosome concept. Immunol. Lett. 2009, 122:118-121.
    • (2009) Immunol. Lett. , vol.122 , pp. 118-121
    • Wilschut, J.1
  • 54
    • 77953756732 scopus 로고    scopus 로고
    • Multiple vaccine-elicited nonneutralizing antienvelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques
    • Xiao P., Zhao J., Patterson L.J., Brocca-Cofano E., Venzon D., Kozlowski P.A., Hidajat R., Demberg T., Robert-Guroff M. Multiple vaccine-elicited nonneutralizing antienvelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques. J. Virol. 2010, 84:7161-7173.
    • (2010) J. Virol. , vol.84 , pp. 7161-7173
    • Xiao, P.1    Zhao, J.2    Patterson, L.J.3    Brocca-Cofano, E.4    Venzon, D.5    Kozlowski, P.A.6    Hidajat, R.7    Demberg, T.8    Robert-Guroff, M.9
  • 55
    • 38049031709 scopus 로고    scopus 로고
    • The binding of HIV-1 gp41 membrane proximal domain to its mucosal receptor, galactosyl ceramide, is structure-dependent
    • Yu H., Alfsen A., Tudor D., Bomsel M. The binding of HIV-1 gp41 membrane proximal domain to its mucosal receptor, galactosyl ceramide, is structure-dependent. Cell Calcium 2008, 43:73-82.
    • (2008) Cell Calcium , vol.43 , pp. 73-82
    • Yu, H.1    Alfsen, A.2    Tudor, D.3    Bomsel, M.4
  • 56
    • 64549126021 scopus 로고    scopus 로고
    • Prolonged protection against Intranasal challenge with influenza virus following systemic immunization or combinations of mucosal and systemic immunizations with a heat-labile toxin mutant
    • Zhou F., Goodsell A., Uematsu Y., Vajdy M. Prolonged protection against Intranasal challenge with influenza virus following systemic immunization or combinations of mucosal and systemic immunizations with a heat-labile toxin mutant. Clin. Vaccine Immunol. 2009, 16:471-478.
    • (2009) Clin. Vaccine Immunol. , vol.16 , pp. 471-478
    • Zhou, F.1    Goodsell, A.2    Uematsu, Y.3    Vajdy, M.4


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