Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins

Journal of Controlled Release

Volumn 61, Issue 1-2, 1999, Pages 233-240

  Nakanishi, Tsuyoshi ^a   Kunisawa, Jun ^a   Hayashi, Akira ^a   Tsutsumi, Yasuo ^a   Kubo, Kazuyoshi ^a   Nakagawa, Shinsaku ^a   Nakanishi, Mahito ^b   Tanaka, Keiichi ^a   Mayumi, Tadanori ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Antigen presenting cell; Cell mediated immune response; Immunoadjuvant; Positively charged liposome

Indexed keywords

IMMUNOLOGICAL ADJUVANT; LEPROSY VACCINE; LIPOSOME; PROTEIN; VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; ELECTRIC POTENTIAL; HUMAN IMMUNODEFICIENCY VIRUS; LEISHMANIA; MOUSE; MYCOBACTERIUM LEPRAE; NONHUMAN; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGEN PRESENTATION; FEMALE; LIPOSOMES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED DBA; OVALBUMIN; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0032816878     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(99)00097-8     Document Type: Article

References (38)

1. Clerici M., Shearer G.M. A TH1→TH2 switch is a critical step in the etiology of HIV infection. Immunol. Today. 14:(3):1993;107-111.
2. Bretscher P.A., Wei G., Menon J.N., Bielefeldt-Ohmann H. Establishment of stable, cell-mediated immunity that makes 'susceptible' mice resistant to Leishmania major. Science. 257:(5069):1992;539-542.
3. Turk J.L., Bryceson A.D.M. Immunological phenomena in leprosy and related diseases. Adv. Immunol. 13:1971;209-266.
4. Shimizu J., Suda T., Yoshioka T., Kosugi A., Fujiwara H., Hamaoka T. Induction of tumor-specific in vivo protective immunity by immunization with tumor antigen-pulsed antigen-presenting cells. J. Immunol. 142:(3):1989;1053-1059.
5. Mayordomo J.I., Zorina T., Storkus W.J., Zitvogel L., Celluzzi C., Falo L.D., Melief C.J., Ildstad S.T., MartinKast W., Deleo A.B., Lotze M.T. Bone marrow-derived dendritic cells pulsed with synthetic tumor peptides elicit protective and therapeutic antitumor immunity. Nat. Med. 1:(12):1995;1297-1302.
6. Hsu F.J., Benike C., Fagnoni F., Liles T.M., Czerwinski D., Taidi B., Engleman E.G., Levy R. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat. Med. 2:(1):1996;52-58.
7. Bohm W., Schirmbeck R., Elbe A., Melber K., Diminky D., Kraal G., van-Rooijen N., Barenholz Y., Reimann J. Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo. J. Immunol. 155:(7):1995;3313-3321.
8. Schwendener R.A., Lagocki P.A., Rahman Y.E. The effects of charge and size on the interaction of unilamellar liposomes with macrophages. Biochim. Biophys. Acta. 772:(1):1984;93-101.
9. Mutsaers S.E., Papadimitriou J.M. Surface charge of macrophages and their interaction with charged particles. J. Leukocyte Biol. 44:(1):1988;17-26.
10. Aramaki Y., Akiyama K., Hara T., Tsuchiya S. Recognition of charged liposomes by rat peritoneal and splenic macrophages: effects of fibronectin on the uptake of charged liposomes. Eur. J. Pharm. Sci. 3:1995;63-70.
11. Mizuguchi H., Nakanishi M., Nakanishi T., Nakagawa T., Nakagawa S., Mayumi T. Application of fusogenic liposomes containing fragment A of diphtheria toxin to cancer therapy. Br. J. Cancer. 73:(4):1996;472-476.
12. Carbone F.R., Bevan M.J. Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo. J. Exp. Med. 171:(2):1990;377-387.
13. Harding C.V., Song R. Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules. J. Immunol. 153:(11):1994;4925-4933.
14. Titus R.G., Chiller J.M. A simple and effective method to assess murine delayed type hypersensitivity to proteins. J. Immunol. Methods. 45:(1):1981;65-78.
15. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods. 65:(1-2):1983;55-63.
16. Harding C.V., Collins D.S., Kanagawa O., Unanue E.R. Liposome-encapsulated antigens engender lysosomal processing for class II MHC presentation and cytosolic processing for class I presentation. J. Immunol. 147:(9):1991;2860-2863.
17. Nair S., Zhou F., Reddy R., Huang L., Rouse B.T. Soluble proteins delivered to dendritic cells via pH-sensitive liposomes induce primary cytotoxic T lymphocyte responses in vitro. J. Exp. Med. 175:(2):1992;609-612.
18. Lee K.D., Oh Y.K., Portnoy D.A., Swanson J.A. Delivery of macromolecules into cytosol using liposomes containing hemolysin from Listeria monocytogenes. J. Biol. Chem. 271:(13):1996;7249-7252.
19. Pfeifer J.D., Wick M.J., Roberts R.L., Findlay K., Normark S.J., Harding C.V. Phagocytic processing of bacterial antigens for class I MHC presentation to T cells. Nature. 361:(6410):1993;359-362.
20. Kovacsovics-Bankowski M., Clark K., Benacerraf B., Rock K.L. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc. Natl. Acad. Sci. USA. 90:(11):1993;4942-4946.
21. + cytolytic T cell responses. J. Exp. Med. 182:(6):1995;1663-1671.
22. Uchida T. Diphtheria toxin; biological activity. Cohen P., Heyningen S.V. Molecular Action of Toxins and Viruses. 1982;1-31 Elsevier, Amsterdam.
23. Yamaizumi M., Mekada E., Uchida T., Okada Y. One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell. 15:(1):1978;245-250.
24. Hsu M.J., Juliano R.L. Interactions of liposomes with the reticuloendothelial system. II: Nonspecific and receptor-mediated uptake of liposomes by mouse peritoneal macrophages. Biochim. Biophys. Acta. 720:(4):1982;411-419.
25. Nishikawa K., Arai H., Inoue K. Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages. J. Biol. Chem. 265:(9):1990;5226-5231.
26. Monastra G., Bruni A. Decreased serum level of tumor necrosis factor in animals treated with lipopolysaccharide and liposomes containing phosphatidylserine. Lymphokine Cytokine Res. 11:(1):1992;39-43.
27. Daemen T., Regts J., Scherphof G.L. Liposomal phosphatidylserine inhibits tumor cytotoxicity of liver macrophages induced by muramyl dipeptide and lipopolysaccharide. Biochim. Biophys. Acta. 1285:(2):1996;219-228.
28. Carr D.J., Guarcello V., Blalock J.E. Phosphatidylserine suppresses antigen-specific IgM production by mice orally administered sheep red blood cells. Proc. Soc. Exp. Biol. Med. 200:(4):1992;548-554.
29. Mizuguchi H., Nakanishi T., Nakanishi M., Nakagawa T., Nakagawa S., Mayumi T. Intratumor administration of fusogenic liposomes containing fragment A of diphtheria toxin suppresses tumor growth. Cancer Lett. 100:(1-2):1996;63-69.
30. Mizuguchi H., Nakagawa T., Nakanishi M., Imazu S., Nakagawa S., Mayumi T. Efficient gene transfer into mammalian cells using fusogenic liposome. Biochem. Biophys. Res. Commun. 218:(1):1996;402-407.
31. Alving C.R. Liposomes as carriers of antigens and adjuvants. J. Immunol. Methods. 140:(1):1991;1-13.
32. Alving C.R., Banerji B., Shiba T., Kotani S., Clements J.D., Richards R.L. Liposomes as vehicles for vaccines. Prog. Clin. Biol. Res. 47:1980;339-355.
33. Oxford J.S., Hockley D.J., Heath T.D., Patterson S. The interaction of influenza virus haemagglutinin with phospholipid vesicles-morphological and immunological studies. J. Gen. Virol. 52:(Pt 2):1981;329-343.
34. Naylor P.T., Larsen H.S., Huang L., Rouse B.T. In vivo induction of anti-herpes simplex virus immune response by type 1 antigens and lipid A incorporated into liposomes. Infect. Immun. 36:(3):1982;1209-1216.
35. Abraham E., Shah S. Intranasal immunization with liposomes containing IL-2 enhances bacterial polysaccharide antigen-specific pulmonary secretory antibody response. J. Immunol. 149:(11):1992;3719-3725.
36. Noguchi Y., Noguchi T., Sato T., Yokoo Y., Itoh S., Yoshida M., Yoshiki T., Akiyoshi K., Sunamoto J., Nakayama E., Shiku H. Priming for in vitro and in vivo anti-human T lymphotropic virus type 1 cellular immunity by virus-related protein reconstituted into liposome. J. Immunol. 146:(10):1991;3599-3603.
37. + cytotoxic T lymphocytes. J. Exp. Med. 176:(6):1992;1739-1744.
38. Collins D.S., Findlay K., Harding C.V. Processing of exogenous liposome-encapsulated antigens in vivo generates class I MHC-restricted T cell responses. J. Immunol. 148:(11):1992;3336-3341.