CD11b+ Peyer's patch dendritic cells secrete IL-6 and induce IgA secretion from naive B cells

Journal of Immunology

Volumn 171, Issue 7, 2003, Pages 3684-3690

  Sato, Ayuko ^a,b   Hashiguchi, Masaaki ^a,d   Toda, Etsuko ^a   Iwasaki, Akiko ^b   Hachimura, Satoshi ^a   Kaminogawa, Shuichi ^a,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NIHON UNIVERSITY   (Japan)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; IMMUNOGLOBULIN A; INTERLEUKIN 6;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; IMMUNOGLOBULIN PRODUCTION; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN FUNCTION; SPLEEN; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

EID: 0141886178     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.7.3684     Document Type: Article

References (40)

1. Mayrhofer, G., C. W. Pugh, and A. N. Barclay. 1983. The distribution, ontogeny and origin in the rat of Ia-positive cells with dendritic morphology and of Ia antigen in epithelia, with special reference to the intestine. Eur. J. Immunol. 13:112.
2. Spencer, I., T. Finn, and P. G. Isaacson. 1986. Human Peyer's patches: an immunohistochemical study. Gut 27:405.
3. Witmer-Pack, M. D., D. A. Hughes, G. Schuler, L. Lawson, A. McWilliam, K. Inaba, R. M. Steinman, and S. Gordon. 1993. Identification of macrophages and dendritic cells in the osteopetrotic (op/op) mouse. J. Cell Sci. 104:1021.
4. Pavli, P., C. E. Woodhams, W. F. Doe, and D. A. Hume. 1990. Isolation and characterization of antigen-presenting dendritic cells from the mouse intestinal lamina propria. Immunology 70:40.
5. Iwasaki, A., and B. L. Kelsall. 1999. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J. Exp. Med, 190:229.
6. Spalding, D. M., W. J. Koopman, J. H. Eldridge, J. R. McGhee, and R. M. Steinman. 1983. Accessory cells in murine Peyer's patch. I. Identification and enrichment of a functional dendritic cell. J. Exp. Med. 157:1646.
7. Spalding, D. M., S. I. Williamson, W. J. Koopman, and J. R. McGhee. 1984. Preferential induction of polyclonal IgA secretion by murine Peyer's patch dendritic cell-T cell mixtures. J. Exp. Med. 160:941.
8. Spalding, D. M., and J. A. Griffin. 1986. Different pathways of differentiation of pre-B cell lines are induced by dendritic cells and T cells from different lymphoid tissues. Cell 44:507.
9. George, A., and J. J. Cebra. 1991. Responses of single germinal-center B cells in T-cell-dependent microculture. Proc. Natl. Acad. Sci. USA 88:11.
10. Iwasaki, A., and B. L. Kelsall. 2000. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3α, MIP-3β, and secondary lymphoid organ chemokine. J. Exp. Med. 191:1381.
11. +, and double-negative Peyer's patch dendritic cells. J. Immunol. 166:4884.
12. Sonoda, E., R. Matsumoto, Y. Hitoshi, T. Ishii, M. Sugimoto, S. Araki, A. Tominaga, N. Yamaguchi, and K. Takatsu. 1989. Transforming growth factor β induces IgA production and acts additively with interleukin 5 for IgA production. J. Exp. Med. 170:1415.
13. Coffman, R. L., D. A. Lebman, and B. Shrader. 1989. Transforming growth factor β specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes. J. Exp. Med. 170:1039.
14. van Ginkel, F. W., S. M. Wahl, J. F. Kearney, M. N. Kweon, K. Fujihashi, P. D. Burrows, H. Kiyono, and J. R. McGhee. 1999. Partial IgA-deficiency with increased Th2-type cytokines in TGF-β1 knockout mice. J. Immunol. 163:1951.
15. Beagley, K. W., J. H. Eldridge, H. Kiyono, M. P. Everson, W. J. Koopman, T. Honjo, and J. R. McGhee. 1988. Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cells. J. Immunol. 141:2035.
16. Harriman, G. R., D. Y. Kunimoto, J. F. Elliott, V. Paetkau, and W. Strober. 1988. The role of IL-5 in IgA B cell differentiation. J. Immunol. 140:3033.
17. Lebman, D. A., and R. L. Coffman. 1988. The effects of IL-4 and IL-5 on the IgA response by murine Peyer's patch B cell subpopulations. J. Immunol. 141:2050.
18. Schoenbeck, S., D. T. McKenzie, and M. F. Kagnoff. 1989. Interleukin 5 is a differentiation factor for IgA B cells. Eur. J. Immunol. 19:965.
19. Kunimoto, D. Y., R. P. Nordan, and W. Strober. 1989. IL-6 is a potent cofactor of IL-1 in IgM synthesis and of IL-5 in IgA synthesis. J. Immunol. 143:2230.
20. + B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 4:15.
21. Beagley, K. W., J. H. Eldridge, F. Lee, H. Kiyono. M. P. Everson, W. J. Koopman, T. Hirano, T. Kishimoto, and J. R. McGhee. 1989. Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells. J. Exp. Med. 169:2133.
22. Ramsay, A. J., A. J. Husband, I. A. Ramshaw, S. Bao, K. I. Matthaei, G. Koehler, and M. Kopf. 1994. The role of interleukin-6 in mucosal IgA antibody responses in vivo. Science 264:561.
23. Kroese, F. G., E. C. Butcher, A. M. Stall, P. A. Lalor, S. Adams, and L. A. Herzenberg. 1989. Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity. Int. Immunol. 1:75.
24. Herzenberg, L. A., A. M. Stall, P. A. Lalor, C. Sidman, W. A. Moore, and D. R. Parks. 1986. The Ly-1 B cell lineage. Immunol. Rev. 93:81.
25. Staal, F. J., M. Roederer, and L. A. Herzenberg. 1992. Glutathione and immunophenotypes of T and B lymphocytes in HIV-infected individuals. Ann. NY Acad. Sci. 651:453.
26. Beagley, K. W., S. Bao, A. J. Ramsay, J. H. Eldridge, and A. J. Husband. 1995. IgA production by peritoneal cavity B cells is IL-6 independent: implications for intestinal IgA responses. Eur. J. Immunol. 25:2123.
27. Sato, T., T. Sasahara, Y. Nakamura, T. Osaki, T. Hasegawa, T. Tadakuma, Y. Arata, Y. Kumagai, M. Katsuki, and S. Habu. 1994. Naive T cells can mediate delayed-type hypersensitivity response in T cell receptor transgenic mice. Eur. J. Immunol. 24:1512.
28. lo thymocytes in vivo. Science 250:1720.
29. Fujihashi, K., J. R. McGhee, C. Lue, K. W. Beagley, T. Taga, T. Hirano, T. Kishimoto, J. Mestecky, and H. Kiyono. 1991. Human appendix B cells naturally express receptors for and respond to interleukin 6 with selective IgA1 and IgA2 synthesis. J. Clin. Invest. 88:248.
30. Bromander, A. K., L. Ekman, M. Kopf, J. G. Nedrud, and N. Y. Lyck. 1996. IL-6-deficient mice exhibit normal mucosal IgA responses to local immunizations and Helicobacter felis infection. J. Immunol. 156:4290.
31. 2-interferon/hepatocyte-stimulating factor/interleukin 6" promoter by cytokines, viruses, and second messenger agonists. Proc. Natl. Acad. Sci. USA 85:6701.
32. Zhang, Y. H., J. X. Lin, Y. K. Yip, and J. Vilcek. 1988. Enhancement of cAMP levels and of protein kinase activity by tumor necrosis factor and interleukin 1 in human fibroblasts: role in the induction of interleukin 6. Proc. Natl. Acad. Sci. USA 85:6802.
33. 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP. J. Biol. Chem. 263:6177.
34. Zhang, Y. H., J. X. Lin, and J. Vilcek. 1990. Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a κB-like sequence. Mol. Cell. Biol. 10:3818.
35. 2-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187. Proc. Natl. Acad. Sci. USA 84:3663.
36. Kang, S. H., D. A. Brown, I. Kitajima, X. Xu, O. Heidenreich, S. Gryaznov, and M. Nerenberg, 1996. Binding and functional effects of transcriptional factor Sp1 on the murine interleukin-6 promotor. J. Biol. Chem. 271:7330.
37. Faggioli, L., M. Merola, J. Hiscott, A. Furia, R. Monese, M. Tovey, and M. Palmieri. 1997. Molecular mechanisms regulating induction of interleukin-6 gene transcription by interferon-γ. Eur. J. Immunol. 27:3022.
38. London, S. D., D. H. Rubin, and J. J. Cebra. 1987. Gut mucosal immunization with reovirus serotype 1/L stimulates virus-specific cytotoxic T cell precursors as well as IgA memory cells in Peyer's patches. J. Exp. Med. 165:830.
39. London, S. D., D. H. Rubin, and J. J. Cebra. 1987. Murine Peyer's patches are capable of generating a cytotoxic T cell (CTL) response to nominal antigens. Adv. Exp. Med. Biol. 216A:267.
40. Okada, M., M. Kitahara, S. Kishimoto, T. Matsuda, T. Hirano, and T. Kishimoto. 1988. IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells. J. Immunol. 141:1543.