β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination

Journal of Controlled Release

Volumn 172, Issue 3, 2013, Pages 671-678

  De Smet, Rebecca ^a   Demoor, Tine ^b   Verschuere, Stephanie ^a   Dullaers, Melissa ^a   Ostroff, Gary R ^c   Leclercq, Georges ^a   Allais, Liesbeth ^a   Pilette, Charles ^d   Dierendonck, Marijke ^a   De Geest, Bruno G ^a   Cuvelier, Claude A ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Antigen delivery; beta; glucan microparticles; Oral vaccination; Peyer's patches; Vaccines

Indexed keywords

ANTIGEN DELIVERY; ANTIGEN DELIVERY SYSTEM; HUMORAL IMMUNE RESPONSE; INTESTINAL EPITHELIAL CELLS; MICRO-PARTICLES; ORAL VACCINATIONS; PEYER'S PATCHES; PRO-INFLAMMATORY CYTOKINES;

CELL CULTURE; CELLS; MAMMALS; T-CELLS; VACCINES;

ANTIGENS;

BETA GLUCAN; DECTIN 1; DRUG CARRIER; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 23P19; INTERLEUKIN 8; OVALBUMIN; SECRETORY COMPONENT; SECRETORY IMMUNOGLOBULIN; TRANSFORMING GROWTH FACTOR BETA;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL STRAIN HT29; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SCREENING; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; INTESTINE FLUID; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH17 CELL; VACCINATION;

ANTIGEN DELIVERY; GP; MESENTERIC LYMPH NODES; MLN; ORAL VACCINATION; PATTERN RECOGNITION RECEPTOR; PEYER'S PATCHES; PIGR; POLYMERIC IMMUNOGLOBULIN RECEPTOR; PP; PRR; S-IGA; SC; SECRETORY COMPONENT; SECRETORY-IMMUNOGLOBULIN A; VACCINES; Β-GLUCAN MICROPARTICLES;

ADMINISTRATION, ORAL; ANIMALS; ANTIGENS; BETA-GLUCANS; CACO-2 CELLS; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; HT29 CELLS; HUMANS; IMMUNOGLOBULIN A; MALE; MICE; MICE, INBRED C57BL; OVALBUMIN; VACCINATION; VACCINES;

EID: 84887178385     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.09.007     Document Type: Article

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