메뉴 건너뛰기




Volumn 37, Issue 5, 2015, Pages 443-451

Genetics of systemic sclerosis

Author keywords

Genetics; HLA; Polymorphism; Scleroderma; SNP; Systemic sclerosis

Indexed keywords

HLA ANTIGEN; INTERFERON; INTERLEUKIN 12; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

EID: 84940893399     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-015-0499-z     Document Type: Review
Times cited : (35)

References (83)
  • 1
    • 0038004795 scopus 로고    scopus 로고
    • Analysis of systemic sclerosis in twins reveals low concordance for disease and high concordance for the presence of antinuclear antibodies
    • PID: 12847690
    • Feghali-Bostwick C, Medsger TA Jr, Wright TM (2003) Analysis of systemic sclerosis in twins reveals low concordance for disease and high concordance for the presence of antinuclear antibodies. Arthritis Rheum 48:1956–1963
    • (2003) Arthritis Rheum , vol.48 , pp. 1956-1963
    • Feghali-Bostwick, C.1    Medsger, T.A.2    Wright, T.M.3
  • 2
    • 0034965980 scopus 로고    scopus 로고
    • Familial occurrence frequencies and relative risks for systemic sclerosis (scleroderma) in three United States cohorts
    • COI: 1:STN:280:DC%2BD3MzksVOnsA%3D%3D, PID: 11407695
    • Arnett FC, Cho M, Chatterjee S, Aguilar MB, Reveille JD, Mayes MD (2001) Familial occurrence frequencies and relative risks for systemic sclerosis (scleroderma) in three United States cohorts. Arthritis Rheum 44:1359–1362
    • (2001) Arthritis Rheum , vol.44 , pp. 1359-1362
    • Arnett, F.C.1    Cho, M.2    Chatterjee, S.3    Aguilar, M.B.4    Reveille, J.D.5    Mayes, M.D.6
  • 3
    • 61649085373 scopus 로고    scopus 로고
    • Familial associations of rheumatoid arthritis with autoimmune diseases and related conditions
    • PID: 19248111
    • Hemminki K, Li X, Sundquist J, Sundquist K (2009) Familial associations of rheumatoid arthritis with autoimmune diseases and related conditions. Arthritis Rheum 60:661–668
    • (2009) Arthritis Rheum , vol.60 , pp. 661-668
    • Hemminki, K.1    Li, X.2    Sundquist, J.3    Sundquist, K.4
  • 4
    • 0035044928 scopus 로고    scopus 로고
    • Systemic sclerosis in 3 US ethnic groups: a comparison of clinical, sociodemographic, serologic, and immunogenetic determinants
    • COI: 1:CAS:528:DC%2BD3MXjsV2ks7c%3D, PID: 11303306
    • Reveille JD, Fischbach M, McNearney T, Friedman AW, Aguilar MB, Lisse J et al (2001) Systemic sclerosis in 3 US ethnic groups: a comparison of clinical, sociodemographic, serologic, and immunogenetic determinants. Semin Arthritis Rheum 30:332–346
    • (2001) Semin Arthritis Rheum , vol.30 , pp. 332-346
    • Reveille, J.D.1    Fischbach, M.2    McNearney, T.3    Friedman, A.W.4    Aguilar, M.B.5    Lisse, J.6
  • 5
    • 84891790401 scopus 로고    scopus 로고
    • The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
    • COI: 1:CAS:528:DC%2BC2cXoslOi, PID: 24316577
    • Welter D, MacArthur J, Morales J, Burdett T, Hall P, Junkins H et al (2014) The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res 42:D1001–1006
    • (2014) Nucleic Acids Res , vol.42 , pp. 1001-1006
    • Welter, D.1    MacArthur, J.2    Morales, J.3    Burdett, T.4    Hall, P.5    Junkins, H.6
  • 6
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447:661-678
    • (2007) Nature , vol.447 , pp. 661-678
  • 7
    • 77951765348 scopus 로고    scopus 로고
    • Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
    • COI: 1:CAS:528:DC%2BC3cXksFalsLw%3D, PID: 20383147
    • Radstake TR, Gorlova O, Rueda B, Martin JE, Alizadeh BZ, Palomino-Morales R et al (2010) Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet 42:426–429
    • (2010) Nat Genet , vol.42 , pp. 426-429
    • Radstake, T.R.1    Gorlova, O.2    Rueda, B.3    Martin, J.E.4    Alizadeh, B.Z.5    Palomino-Morales, R.6
  • 8
    • 33845663156 scopus 로고    scopus 로고
    • Association of the PTPN22 R620 W polymorphism with anti-topoisomerase I- and anticentromere antibodypositive systemic sclerosis
    • Gourh P et al (2006) Association of the PTPN22 R620 W polymorphism with anti-topoisomerase I- and anticentromere antibodypositive systemic sclerosis. Arthritis Rheum 54:3945–3953
    • (2006) Arthritis Rheum , vol.54 , pp. 3945-3953
    • Gourh, P.1
  • 9
    • 47249105581 scopus 로고    scopus 로고
    • The PTPN22 620 W allele confers susceptibility to sysremic sclerosis: Wndings of a large case-control study of european Causcasians and a meta-analysis
    • Dieude P et al (2008) The PTPN22 620 W allele confers susceptibility to sysremic sclerosis: Wndings of a large case-control study of european Causcasians and a meta-analysis. Arthritis Rheum 58:2183–2188
    • (2008) Arthritis Rheum , vol.58 , pp. 2183-2188
    • Dieude, P.1
  • 10
    • 73249152055 scopus 로고    scopus 로고
    • HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans
    • COI: 1:CAS:528:DC%2BC3cXhtFKhtbzM, PID: 19950302
    • Zhou X, Lee JE, Arnett FC, Xiong M, Park MY, Yoo YK et al (2009) HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans. Arthritis Rheum 60:3807–3814
    • (2009) Arthritis Rheum , vol.60 , pp. 3807-3814
    • Zhou, X.1    Lee, J.E.2    Arnett, F.C.3    Xiong, M.4    Park, M.Y.5    Yoo, Y.K.6
  • 11
    • 79960934301 scopus 로고    scopus 로고
    • Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis
    • COI: 1:CAS:528:DC%2BC3MXpsFCns74%3D, PID: 21750679
    • Allanore Y, Saad M, Dieude P, Avouac J, Distler JH, Amouyel P et al (2011) Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. PLoS Genet 7:e1002091
    • (2011) PLoS Genet , vol.7 , pp. 1002091
    • Allanore, Y.1    Saad, M.2    Dieude, P.3    Avouac, J.4    Distler, J.H.5    Amouyel, P.6
  • 13
    • 0035320790 scopus 로고    scopus 로고
    • Class II HLA associations with autoantibodies in scleroderma: a highly significant role for HLA-DP
    • COI: 1:CAS:528:DC%2BD3MXjtFKntbc%3D, PID: 11393660
    • Gilchrist FC, Bunn C, Foley PJ, Lympany PA, Black CM, Welsh KI et al (2001) Class II HLA associations with autoantibodies in scleroderma: a highly significant role for HLA-DP. Genes Immun 2:76–81
    • (2001) Genes Immun , vol.2 , pp. 76-81
    • Gilchrist, F.C.1    Bunn, C.2    Foley, P.J.3    Lympany, P.A.4    Black, C.M.5    Welsh, K.I.6
  • 14
    • 77951517869 scopus 로고    scopus 로고
    • Major histocompatibility complex (MHC) class II alleles, haplotypes and epitopes which confer susceptibility or protection in systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls
    • COI: 1:CAS:528:DC%2BC3cXntlOks70%3D, PID: 19596691
    • Arnett FC, Gourh P, Shete S, Ahn CW, Honey RE, Agarwal SK et al (2010) Major histocompatibility complex (MHC) class II alleles, haplotypes and epitopes which confer susceptibility or protection in systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls. Ann Rheum Dis 69:822–827
    • (2010) Ann Rheum Dis , vol.69 , pp. 822-827
    • Arnett, F.C.1    Gourh, P.2    Shete, S.3    Ahn, C.W.4    Honey, R.E.5    Agarwal, S.K.6
  • 15
    • 84855181107 scopus 로고    scopus 로고
    • Analysis of Class II human leucocyte antigens in Italian and Spanish systemic sclerosis
    • COI: 1:CAS:528:DC%2BC3MXhs12htLbI
    • Beretta L, Rueda B, Marchini M, Santaniello A, Simeon CP, Fonollosa V et al (2012) Analysis of Class II human leucocyte antigens in Italian and Spanish systemic sclerosis. Rheumatology (Oxford) 51:52–59
    • (2012) Rheumatology (Oxford) , vol.51 , pp. 52-59
    • Beretta, L.1    Rueda, B.2    Marchini, M.3    Santaniello, A.4    Simeon, C.P.5    Fonollosa, V.6
  • 16
    • 84882449068 scopus 로고    scopus 로고
    • Genetic insights into common pathways and complex relationships among immune-mediated diseases
    • COI: 1:CAS:528:DC%2BC3sXht1WrtLfJ, PID: 23917628
    • Parkes M, Cortes A, van Heel DA, Brown MA (2013) Genetic insights into common pathways and complex relationships among immune-mediated diseases. Nat Rev Genet 14:661–673
    • (2013) Nat Rev Genet , vol.14 , pp. 661-673
    • Parkes, M.1    Cortes, A.2    van Heel, D.A.3    Brown, M.A.4
  • 17
    • 84862776511 scopus 로고    scopus 로고
    • Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC38XhtlOmurk%3D, PID: 22286218
    • Raychaudhuri S, Sandor C, Stahl EA, Freudenberg J, Lee HS, Jia X et al (2012) Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat Genet 44:291–296
    • (2012) Nat Genet , vol.44 , pp. 291-296
    • Raychaudhuri, S.1    Sandor, C.2    Stahl, E.A.3    Freudenberg, J.4    Lee, H.S.5    Jia, X.6
  • 18
    • 84891817885 scopus 로고    scopus 로고
    • Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis
    • COI: 1:CAS:528:DC%2BC2cXisVCitQ%3D%3D, PID: 24387989
    • Mayes MD, Bossini-Castillo L, Gorlova O, Martin JE, Zhou X, Chen WV et al (2014) Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. Am J Hum Genet 94:47–61
    • (2014) Am J Hum Genet , vol.94 , pp. 47-61
    • Mayes, M.D.1    Bossini-Castillo, L.2    Gorlova, O.3    Martin, J.E.4    Zhou, X.5    Chen, W.V.6
  • 19
  • 20
    • 48249083459 scopus 로고    scopus 로고
    • Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan
    • PID: 18604266
    • Nielsen M, Lundegaard C, Blicher T, Peters B, Sette A, Justesen S et al (2008) Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan. PLoS Comput Biol 4:e1000107
    • (2008) PLoS Comput Biol , vol.4 , pp. 1000107
    • Nielsen, M.1    Lundegaard, C.2    Blicher, T.3    Peters, B.4    Sette, A.5    Justesen, S.6
  • 21
    • 84925089678 scopus 로고    scopus 로고
    • The role of regulatory variation in complex traits and disease
    • COI: 1:CAS:528:DC%2BC2MXjt1Sgu7Y%3D, PID: 25707927
    • Albert FW, Kruglyak L (2015) The role of regulatory variation in complex traits and disease. Nat Rev Genet 16:197–212
    • (2015) Nat Rev Genet , vol.16 , pp. 197-212
    • Albert, F.W.1    Kruglyak, L.2
  • 22
    • 84925719346 scopus 로고    scopus 로고
    • Regulation of antiviral T cell responses by type I interferons
    • COI: 1:CAS:528:DC%2BC2MXkvVygu7k%3D, PID: 25790790
    • Crouse J, Kalinke U, Oxenius A (2015) Regulation of antiviral T cell responses by type I interferons. Nat Rev Immunol 15:231–242
    • (2015) Nat Rev Immunol , vol.15 , pp. 231-242
    • Crouse, J.1    Kalinke, U.2    Oxenius, A.3
  • 24
    • 84886081492 scopus 로고    scopus 로고
    • The role of type 1 interferon in systemic sclerosis
    • PID: 24046769
    • Wu M, Assassi S (2013) The role of type 1 interferon in systemic sclerosis. Front Immunol 4:266
    • (2013) Front Immunol , vol.4 , pp. 266
    • Wu, M.1    Assassi, S.2
  • 25
    • 7244242345 scopus 로고    scopus 로고
    • Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection
    • COI: 1:CAS:528:DC%2BD2cXosFyls7k%3D, PID: 15308637
    • Barnes BJ, Richards J, Mancl M, Hanash S, Beretta L, Pitha PM (2004) Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection. J Biol Chem 279:45194–45207
    • (2004) J Biol Chem , vol.279 , pp. 45194-45207
    • Barnes, B.J.1    Richards, J.2    Mancl, M.3    Hanash, S.4    Beretta, L.5    Pitha, P.M.6
  • 27
    • 66449100302 scopus 로고    scopus 로고
    • Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population
    • COI: 1:CAS:528:DC%2BD1MXotVeqt7s%3D, PID: 19479858
    • Ito I, Kawaguchi Y, Kawasaki A, Hasegawa M, Ohashi J, Hikami K et al (2009) Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population. Arthritis Rheum 60:1845–1850
    • (2009) Arthritis Rheum , vol.60 , pp. 1845-1850
    • Ito, I.1    Kawaguchi, Y.2    Kawasaki, A.3    Hasegawa, M.4    Ohashi, J.5    Hikami, K.6
  • 28
    • 58249123282 scopus 로고    scopus 로고
    • Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis
    • COI: 1:CAS:528:DC%2BD1MXhvFCjsr8%3D, PID: 19116937
    • Dieude P, Guedj M, Wipff J, Avouac J, Fajardy I, Diot E et al (2009) Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis. Arthritis Rheum 60:225–233
    • (2009) Arthritis Rheum , vol.60 , pp. 225-233
    • Dieude, P.1    Guedj, M.2    Wipff, J.3    Avouac, J.4    Fajardy, I.5    Diot, E.6
  • 29
    • 77951792926 scopus 로고    scopus 로고
    • Phenotype-haplotype correlation of IRF5 in systemic sclerosis: role of 2 haplotypes in disease severity
    • COI: 1:CAS:528:DC%2BC3cXnsFOrs78%3D, PID: 20231204
    • Dieude P, Dawidowicz K, Guedj M, Legrain Y, Wipff J, Hachulla E et al (2010) Phenotype-haplotype correlation of IRF5 in systemic sclerosis: role of 2 haplotypes in disease severity. J Rheumatol 37:987–992
    • (2010) J Rheumatol , vol.37 , pp. 987-992
    • Dieude, P.1    Dawidowicz, K.2    Guedj, M.3    Legrain, Y.4    Wipff, J.5    Hachulla, E.6
  • 30
    • 84872779755 scopus 로고    scopus 로고
    • The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis
    • COI: 1:CAS:528:DC%2BC3sXitVyls7g%3D, PID: 23372721
    • Carmona FD, Martin JE, Beretta L, Simeon CP, Carreira PE, Callejas JL et al (2013) The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis. PLoS One 8:e54419
    • (2013) PLoS One , vol.8 , pp. 54419
    • Carmona, F.D.1    Martin, J.E.2    Beretta, L.3    Simeon, C.P.4    Carreira, P.E.5    Callejas, J.L.6
  • 31
    • 84922444783 scopus 로고    scopus 로고
    • The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share
    • COI: 1:CAS:528:DC%2BC2MXjsVKktbk%3D, PID: 25205108
    • Kottyan LC, Zoller EE, Bene J, Lu X, Kelly JA, Rupert AM et al (2015) The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share. Hum Mol Genet 24:582–596
    • (2015) Hum Mol Genet , vol.24 , pp. 582-596
    • Kottyan, L.C.1    Zoller, E.E.2    Bene, J.3    Lu, X.4    Kelly, J.A.5    Rupert, A.M.6
  • 32
    • 84862789262 scopus 로고    scopus 로고
    • IRF5 polymorphism predicts prognosis in patients with systemic sclerosis
    • COI: 1:CAS:528:DC%2BC38Xht1OgtLfK, PID: 22440820
    • Sharif R, Mayes MD, Tan FK, Gorlova OY, Hummers LK, Shah AA et al (2012) IRF5 polymorphism predicts prognosis in patients with systemic sclerosis. Ann Rheum Dis 71:1197–1202
    • (2012) Ann Rheum Dis , vol.71 , pp. 1197-1202
    • Sharif, R.1    Mayes, M.D.2    Tan, F.K.3    Gorlova, O.Y.4    Hummers, L.K.5    Shah, A.A.6
  • 33
    • 79960943814 scopus 로고    scopus 로고
    • Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy
    • COI: 1:CAS:528:DC%2BC3MXhtVSlt7rM, PID: 21779181
    • Gorlova O, Martin JE, Rueda B, Koeleman BP, Ying J, Teruel M et al (2011) Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. PLoS Genet 7:e1002178
    • (2011) PLoS Genet , vol.7 , pp. 1002178
    • Gorlova, O.1    Martin, J.E.2    Rueda, B.3    Koeleman, B.P.4    Ying, J.5    Teruel, M.6
  • 34
    • 66549125977 scopus 로고    scopus 로고
    • IRF8 regulates myeloid and B lymphoid lineage diversification
    • COI: 1:CAS:528:DC%2BD1MXjsFyls7g%3D, PID: 18806934
    • Wang H, Morse HC 3rd (2009) IRF8 regulates myeloid and B lymphoid lineage diversification. Immunol Res 43:109–117
    • (2009) Immunol Res , vol.43 , pp. 109-117
    • Wang, H.1    Morse, H.C.2
  • 35
    • 82955245641 scopus 로고    scopus 로고
    • Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis
    • COI: 1:CAS:528:DC%2BC38Xhs1yiurk%3D, PID: 21926187
    • Carmona FD, Gutala R, Simeon CP, Carreira P, Ortego-Centeno N, Vicente-Rabaneda E et al (2012) Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis. Ann Rheum Dis 71:114–119
    • (2012) Ann Rheum Dis , vol.71 , pp. 114-119
    • Carmona, F.D.1    Gutala, R.2    Simeon, C.P.3    Carreira, P.4    Ortego-Centeno, N.5    Vicente-Rabaneda, E.6
  • 36
    • 17144404177 scopus 로고    scopus 로고
    • IRF-7 is the master regulator of type-I interferon-dependent immune responses
    • COI: 1:CAS:528:DC%2BD2MXivFCgurg%3D, PID: 15800576
    • Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T et al (2005) IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434:772–777
    • (2005) Nature , vol.434 , pp. 772-777
    • Honda, K.1    Yanai, H.2    Negishi, H.3    Asagiri, M.4    Sato, M.5    Mizutani, T.6
  • 37
    • 0031057296 scopus 로고    scopus 로고
    • Function and clinical use of interleukin-12
    • COI: 1:STN:280:DyaK2s7ps1elsg%3D%3D, PID: 9050381
    • Trinchieri G (1997) Function and clinical use of interleukin-12. Curr Opin Hematol 4:59–66
    • (1997) Curr Opin Hematol , vol.4 , pp. 59-66
    • Trinchieri, G.1
  • 38
    • 84869882029 scopus 로고    scopus 로고
    • Genetic variations in interleukin-12 related genes in immune-mediated diseases
    • PID: 22819329
    • van Wanrooij RL, Zwiers A, Kraal G, Bouma G (2012) Genetic variations in interleukin-12 related genes in immune-mediated diseases. J Autoimmun 39:359–368
    • (2012) J Autoimmun , vol.39 , pp. 359-368
    • van Wanrooij, R.L.1    Zwiers, A.2    Kraal, G.3    Bouma, G.4
  • 39
    • 84863043315 scopus 로고    scopus 로고
    • A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations
    • COI: 1:CAS:528:DC%2BC38XhsVantLg%3D, PID: 22076442
    • Bossini-Castillo L, Martin JE, Broen J, Gorlova O, Simeon CP, Beretta L et al (2012) A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations. Hum Mol Genet 21:926–933
    • (2012) Hum Mol Genet , vol.21 , pp. 926-933
    • Bossini-Castillo, L.1    Martin, J.E.2    Broen, J.3    Gorlova, O.4    Simeon, C.P.5    Beretta, L.6
  • 41
    • 84904418489 scopus 로고    scopus 로고
    • Therapeutic potential of STAT4 in autoimmunity
    • COI: 1:CAS:528:DC%2BC2cXhtFylu7nJ, PID: 24844303
    • Liang Y, Pan HF, Ye DQ (2014) Therapeutic potential of STAT4 in autoimmunity. Expert Opin Ther Targets 18:945–960
    • (2014) Expert Opin Ther Targets , vol.18 , pp. 945-960
    • Liang, Y.1    Pan, H.F.2    Ye, D.Q.3
  • 42
    • 0037144547 scopus 로고    scopus 로고
    • Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection
    • COI: 1:CAS:528:DC%2BD38Xnt1ansLk%3D, PID: 12242445
    • Nguyen KB, Watford WT, Salomon R, Hofmann SR, Pien GC, Morinobu A et al (2002) Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection. Science 297:2063–2066
    • (2002) Science , vol.297 , pp. 2063-2066
    • Nguyen, K.B.1    Watford, W.T.2    Salomon, R.3    Hofmann, S.R.4    Pien, G.C.5    Morinobu, A.6
  • 43
    • 65549154046 scopus 로고    scopus 로고
    • The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype
    • COI: 1:CAS:528:DC%2BD1MXlslWqtrg%3D, PID: 19286670
    • Rueda B, Broen J, Simeon C, Hesselstrand R, Diaz B, Suarez H et al (2009) The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype. Hum Mol Genet 18:2071–2077
    • (2009) Hum Mol Genet , vol.18 , pp. 2071-2077
    • Rueda, B.1    Broen, J.2    Simeon, C.3    Hesselstrand, R.4    Diaz, B.5    Suarez, H.6
  • 44
    • 68049112537 scopus 로고    scopus 로고
    • STAT4 is a genetic risk factor for systemic sclerosis having additive effects with IRF5 on disease susceptibility and related pulmonary fibrosis
    • COI: 1:CAS:528:DC%2BD1MXhtV2hsLfK, PID: 19644887
    • Dieude P, Guedj M, Wipff J, Ruiz B, Hachulla E, Diot E et al (2009) STAT4 is a genetic risk factor for systemic sclerosis having additive effects with IRF5 on disease susceptibility and related pulmonary fibrosis. Arthritis Rheum 60:2472–2479
    • (2009) Arthritis Rheum , vol.60 , pp. 2472-2479
    • Dieude, P.1    Guedj, M.2    Wipff, J.3    Ruiz, B.4    Hachulla, E.5    Diot, E.6
  • 45
    • 73249149749 scopus 로고    scopus 로고
    • Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines
    • COI: 1:CAS:528:DC%2BC3cXhtFKhtb%2FF, PID: 19950257
    • Gourh P, Agarwal SK, Divecha D, Assassi S, Paz G, Arora-Singh RK et al (2009) Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines. Arthritis Rheum 60:3794–3806
    • (2009) Arthritis Rheum , vol.60 , pp. 3794-3806
    • Gourh, P.1    Agarwal, S.K.2    Divecha, D.3    Assassi, S.4    Paz, G.5    Arora-Singh, R.K.6
  • 46
    • 67651229653 scopus 로고    scopus 로고
    • Association of STAT4 polymorphism with systemic sclerosis in a Japanese population
    • COI: 1:CAS:528:DC%2BD1MXhtFGqsrjL, PID: 19605749
    • Tsuchiya N, Kawasaki A, Hasegawa M, Fujimoto M, Takehara K, Kawaguchi Y et al (2009) Association of STAT4 polymorphism with systemic sclerosis in a Japanese population. Ann Rheum Dis 68:1375–1376
    • (2009) Ann Rheum Dis , vol.68 , pp. 1375-1376
    • Tsuchiya, N.1    Kawasaki, A.2    Hasegawa, M.3    Fujimoto, M.4    Takehara, K.5    Kawaguchi, Y.6
  • 47
    • 84881231093 scopus 로고    scopus 로고
    • STAT4 is a genetic risk factor for systemic sclerosis in a Chinese population
    • COI: 1:CAS:528:DC%2BC3sXht1WktLnO, PID: 23755762
    • Yi L, Wang JC, Guo XJ, Gu YH, Tu WZ, Guo G et al (2013) STAT4 is a genetic risk factor for systemic sclerosis in a Chinese population. Int J Immunopathol Pharmacol 26:473–478
    • (2013) Int J Immunopathol Pharmacol , vol.26 , pp. 473-478
    • Yi, L.1    Wang, J.C.2    Guo, X.J.3    Gu, Y.H.4    Tu, W.Z.5    Guo, G.6
  • 48
    • 79953676584 scopus 로고    scopus 로고
    • Inactivation of the transcription factor STAT-4 prevents inflammation-driven fibrosis in animal models of systemic sclerosis
    • COI: 1:CAS:528:DC%2BC3MXksFWrs7k%3D, PID: 21360510
    • Avouac J, Furnrohr BG, Tomcik M, Palumbo K, Zerr P, Horn A et al (2011) Inactivation of the transcription factor STAT-4 prevents inflammation-driven fibrosis in animal models of systemic sclerosis. Arthritis Rheum 63:800–809
    • (2011) Arthritis Rheum , vol.63 , pp. 800-809
    • Avouac, J.1    Furnrohr, B.G.2    Tomcik, M.3    Palumbo, K.4    Zerr, P.5    Horn, A.6
  • 49
    • 79960930749 scopus 로고    scopus 로고
    • Targeting STAT4 in systemic sclerosis: a promising new direction
    • COI: 1:CAS:528:DC%2BC3MXhtFaiu7bL, PID: 21790287
    • Barnes J, Agarwal SK (2011) Targeting STAT4 in systemic sclerosis: a promising new direction. Expert Rev Clin Immunol 7:445–448
    • (2011) Expert Rev Clin Immunol , vol.7 , pp. 445-448
    • Barnes, J.1    Agarwal, S.K.2
  • 50
    • 0031570688 scopus 로고    scopus 로고
    • Identification, localization, and expression of two novel human genes similar to deoxyribonuclease I
    • COI: 1:CAS:528:DyaK2sXktFOlsbg%3D, PID: 9205125
    • Rodriguez AM, Rodin D, Nomura H, Morton CC, Weremowicz S, Schneider MC (1997) Identification, localization, and expression of two novel human genes similar to deoxyribonuclease I. Genomics 42:507–513
    • (1997) Genomics , vol.42 , pp. 507-513
    • Rodriguez, A.M.1    Rodin, D.2    Nomura, H.3    Morton, C.C.4    Weremowicz, S.5    Schneider, M.C.6
  • 51
    • 82255192363 scopus 로고    scopus 로고
    • Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BC3MXhtlGksL%2FF, PID: 22019780
    • Al-Mayouf SM, Sunker A, Abdwani R, Abrawi SA, Almurshedi F, Alhashmi N et al (2011) Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus. Nat Genet 43:1186–1188
    • (2011) Nat Genet , vol.43 , pp. 1186-1188
    • Al-Mayouf, S.M.1    Sunker, A.2    Abdwani, R.3    Abrawi, S.A.4    Almurshedi, F.5    Alhashmi, N.6
  • 52
    • 84891834268 scopus 로고    scopus 로고
    • Evaluation of all non-synonymous single nucleotide polymorphisms (SNPs) in the genes encoding human deoxyribonuclease I and I-like 3 as a functional SNP potentially implicated in autoimmunity
    • COI: 1:CAS:528:DC%2BC2cXosVOh, PID: 24206041
    • Ueki M, Kimura-Kataoka K, Takeshita H, Fujihara J, Iida R, Sano R et al (2014) Evaluation of all non-synonymous single nucleotide polymorphisms (SNPs) in the genes encoding human deoxyribonuclease I and I-like 3 as a functional SNP potentially implicated in autoimmunity. FEBS J 281:376–390
    • (2014) FEBS J , vol.281 , pp. 376-390
    • Ueki, M.1    Kimura-Kataoka, K.2    Takeshita, H.3    Fujihara, J.4    Iida, R.5    Sano, R.6
  • 53
    • 84988843948 scopus 로고    scopus 로고
    • An Immunochip-based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3
    • PID: 25332064
    • Zochling J, Newell F, Charlesworth JC, Leo P, Stankovich J, Cortes A et al (2014) An Immunochip-based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3. Arthritis Res Ther 16:438
    • (2014) Arthritis Res Ther , vol.16 , pp. 438
    • Zochling, J.1    Newell, F.2    Charlesworth, J.C.3    Leo, P.4    Stankovich, J.5    Cortes, A.6
  • 54
    • 84888993757 scopus 로고    scopus 로고
    • A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci
    • COI: 1:CAS:528:DC%2BC3sXhvVGqu73F, PID: 23740937
    • Martin JE, Assassi S, Diaz-Gallo LM, Broen JC, Simeon CP, Castellvi I et al (2013) A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci. Hum Mol Genet 22:4021–4029
    • (2013) Hum Mol Genet , vol.22 , pp. 4021-4029
    • Martin, J.E.1    Assassi, S.2    Diaz-Gallo, L.M.3    Broen, J.C.4    Simeon, C.P.5    Castellvi, I.6
  • 55
    • 84883717351 scopus 로고    scopus 로고
    • Autophagy and autoimmunity crosstalks
    • PID: 23596443
    • Bhattacharya A, Eissa NT (2013) Autophagy and autoimmunity crosstalks. Front Immunol 4:88
    • (2013) Front Immunol , vol.4 , pp. 88
    • Bhattacharya, A.1    Eissa, N.T.2
  • 57
    • 84891678660 scopus 로고    scopus 로고
    • A synthetic PPAR-gamma agonist triterpenoid ameliorates experimental fibrosis: PPAR-gamma-independent suppression of fibrotic responses
    • COI: 1:CAS:528:DC%2BC2cXltFKhs7g%3D, PID: 23515440
    • Wei J, Zhu H, Komura K, Lord G, Tomcik M, Wang W et al (2014) A synthetic PPAR-gamma agonist triterpenoid ameliorates experimental fibrosis: PPAR-gamma-independent suppression of fibrotic responses. Ann Rheum Dis 73:446–454
    • (2014) Ann Rheum Dis , vol.73 , pp. 446-454
    • Wei, J.1    Zhu, H.2    Komura, K.3    Lord, G.4    Tomcik, M.5    Wang, W.6
  • 59
    • 80051468916 scopus 로고    scopus 로고
    • Independent replication establishes the CD247 gene as a genetic systemic sclerosis susceptibility factor
    • COI: 1:CAS:528:DC%2BC3MXht1Cru7vP, PID: 21474487
    • Dieude P, Boileau C, Guedj M, Avouac J, Ruiz B, Hachulla E et al (2011) Independent replication establishes the CD247 gene as a genetic systemic sclerosis susceptibility factor. Ann Rheum Dis 70:1695–1696
    • (2011) Ann Rheum Dis , vol.70 , pp. 1695-1696
    • Dieude, P.1    Boileau, C.2    Guedj, M.3    Avouac, J.4    Ruiz, B.5    Hachulla, E.6
  • 60
    • 84928883896 scopus 로고    scopus 로고
    • Lack of Association of the CD247 SNP rs2056626 with systemic sclerosis in Han Chinese
    • Wang J, Yi L, Guo X, He D, Li H, Guo G et al (2014) Lack of Association of the CD247 SNP rs2056626 with systemic sclerosis in Han Chinese. Open Rheum J 8:43–45
    • (2014) Open Rheum J , vol.8 , pp. 43-45
    • Wang, J.1    Yi, L.2    Guo, X.3    He, D.4    Li, H.5    Guo, G.6
  • 61
    • 84869780894 scopus 로고    scopus 로고
    • Regulation of the SRC family kinases by Csk
    • COI: 1:CAS:528:DC%2BC38XhslajtbnO, PID: 23139636
    • Okada M (2012) Regulation of the SRC family kinases by Csk. Int J Biol Sci 8:1385–1397
    • (2012) Int J Biol Sci , vol.8 , pp. 1385-1397
    • Okada, M.1
  • 62
    • 84861727232 scopus 로고    scopus 로고
    • Identification of CSK as a systemic sclerosis genetic risk factor through genome wide association study follow-up
    • COI: 1:CAS:528:DC%2BC38XnsFGisLY%3D, PID: 22407130
    • Martin JE, Broen JC, Carmona FD, Teruel M, Simeon CP, Vonk MC et al (2012) Identification of CSK as a systemic sclerosis genetic risk factor through genome wide association study follow-up. Hum Mol Genet 21:2825–2835
    • (2012) Hum Mol Genet , vol.21 , pp. 2825-2835
    • Martin, J.E.1    Broen, J.C.2    Carmona, F.D.3    Teruel, M.4    Simeon, C.P.5    Vonk, M.C.6
  • 63
    • 84862776528 scopus 로고    scopus 로고
    • LYP inhibits T-cell activation when dissociated from CSK
    • COI: 1:CAS:528:DC%2BC38XktVaksb0%3D, PID: 22426112
    • Vang T, Liu WH, Delacroix L, Wu S, Vasile S, Dahl R et al (2012) LYP inhibits T-cell activation when dissociated from CSK. Nat Chem Biol 8:437–446
    • (2012) Nat Chem Biol , vol.8 , pp. 437-446
    • Vang, T.1    Liu, W.H.2    Delacroix, L.3    Wu, S.4    Vasile, S.5    Dahl, R.6
  • 64
    • 77956216562 scopus 로고    scopus 로고
    • Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue
    • COI: 1:CAS:528:DC%2BC3cXhtVahtbfM, PID: 20538612
    • Fiorillo E, Orru V, Stanford SM, Liu Y, Salek M, Rapini N et al (2010) Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue. J Biol Chem 285:26506–26518
    • (2010) J Biol Chem , vol.285 , pp. 26506-26518
    • Fiorillo, E.1    Orru, V.2    Stanford, S.M.3    Liu, Y.4    Salek, M.5    Rapini, N.6
  • 65
    • 79951512546 scopus 로고    scopus 로고
    • Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis
    • COI: 1:STN:280:DC%2BC3M7ms1WmtQ%3D%3D, PID: 21131644
    • Diaz-Gallo LM, Gourh P, Broen J, Simeon C, Fonollosa V, Ortego-Centeno N et al (2011) Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis. Ann Rheum Dis 70:454–462
    • (2011) Ann Rheum Dis , vol.70 , pp. 454-462
    • Diaz-Gallo, L.M.1    Gourh, P.2    Broen, J.3    Simeon, C.4    Fonollosa, V.5    Ortego-Centeno, N.6
  • 66
    • 84922280087 scopus 로고    scopus 로고
    • Abnormal B lymphocyte activation and function in systemic sclerosis
    • PID: 25673924
    • Yoshizaki A, Sato S (2015) Abnormal B lymphocyte activation and function in systemic sclerosis. Ann Dermatol 27:1–9
    • (2015) Ann Dermatol , vol.27 , pp. 1-9
    • Yoshizaki, A.1    Sato, S.2
  • 67
    • 70350521796 scopus 로고    scopus 로고
    • BANK1 is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects with IRF5 and STAT4
    • COI: 1:CAS:528:DC%2BD1MXhsFentLzL, PID: 19877059
    • Dieude P, Wipff J, Guedj M, Ruiz B, Melchers I, Hachulla E et al (2009) BANK1 is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects with IRF5 and STAT4. Arthritis Rheum 60:3447–3454
    • (2009) Arthritis Rheum , vol.60 , pp. 3447-3454
    • Dieude, P.1    Wipff, J.2    Guedj, M.3    Ruiz, B.4    Melchers, I.5    Hachulla, E.6
  • 68
    • 77950315193 scopus 로고    scopus 로고
    • BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians
    • COI: 1:CAS:528:DC%2BC3cXltlektrg%3D, PID: 19815934
    • Rueda B, Gourh P, Broen J, Agarwal SK, Simeon C, Ortego-Centeno N et al (2010) BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians. Ann Rheum Dis 69:700–705
    • (2010) Ann Rheum Dis , vol.69 , pp. 700-705
    • Rueda, B.1    Gourh, P.2    Broen, J.3    Agarwal, S.K.4    Simeon, C.5    Ortego-Centeno, N.6
  • 69
    • 79959856965 scopus 로고    scopus 로고
    • C8orf13-BLK is a genetic risk locus for systemic sclerosis and has additive effects with BANK1: results from a large french cohort and meta-analysis
    • COI: 1:CAS:528:DC%2BC3MXotFyhsb0%3D, PID: 21480188
    • Coustet B, Dieude P, Guedj M, Bouaziz M, Avouac J, Ruiz B et al (2011) C8orf13-BLK is a genetic risk locus for systemic sclerosis and has additive effects with BANK1: results from a large french cohort and meta-analysis. Arthritis Rheum 63:2091–2096
    • (2011) Arthritis Rheum , vol.63 , pp. 2091-2096
    • Coustet, B.1    Dieude, P.2    Guedj, M.3    Bouaziz, M.4    Avouac, J.5    Ruiz, B.6
  • 70
    • 77649114558 scopus 로고    scopus 로고
    • Association of the FAM167A-BLK region with systemic sclerosis
    • COI: 1:CAS:528:DC%2BC3cXhtFaltLjM, PID: 20131239
    • Ito I, Kawaguchi Y, Kawasaki A, Hasegawa M, Ohashi J, Kawamoto M et al (2010) Association of the FAM167A-BLK region with systemic sclerosis. Arthritis Rheum 62:890–895
    • (2010) Arthritis Rheum , vol.62 , pp. 890-895
    • Ito, I.1    Kawaguchi, Y.2    Kawasaki, A.3    Hasegawa, M.4    Ohashi, J.5    Kawamoto, M.6
  • 71
    • 75349113494 scopus 로고    scopus 로고
    • Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations
    • COI: 1:CAS:528:DC%2BC3cXhs1Glsbc%3D, PID: 19796918
    • Gourh P, Agarwal SK, Martin E, Divecha D, Rueda B, Bunting H et al (2010) Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations. J Autoimmun 34:155–162
    • (2010) J Autoimmun , vol.34 , pp. 155-162
    • Gourh, P.1    Agarwal, S.K.2    Martin, E.3    Divecha, D.4    Rueda, B.5    Bunting, H.6
  • 72
    • 84915737222 scopus 로고    scopus 로고
    • Possible single-nucleotide polymorphism loci associated with systemic sclerosis susceptibility: a genetic association study in a Chinese Han population
    • PID: 25470816
    • Shu C, Du W, Mao X, Li Y, Zhu Q, Wang W et al (2014) Possible single-nucleotide polymorphism loci associated with systemic sclerosis susceptibility: a genetic association study in a Chinese Han population. PLoS One 9:e113197
    • (2014) PLoS One , vol.9 , pp. 113197
    • Shu, C.1    Du, W.2    Mao, X.3    Li, Y.4    Zhu, Q.5    Wang, W.6
  • 73
    • 84873832733 scopus 로고    scopus 로고
    • Tumor necrosis factor-costimulated T lymphocytes from patients with systemic sclerosis trigger collagen production in fibroblasts
    • PID: 23045159
    • Hugle T, O'Reilly S, Simpson R, Kraaij MD, Bigley V, Collin M et al (2013) Tumor necrosis factor-costimulated T lymphocytes from patients with systemic sclerosis trigger collagen production in fibroblasts. Arthritis Rheum 65:481–491
    • (2013) Arthritis Rheum , vol.65 , pp. 481-491
    • Hugle, T.1    O'Reilly, S.2    Simpson, R.3    Kraaij, M.D.4    Bigley, V.5    Collin, M.6
  • 74
    • 84899047993 scopus 로고    scopus 로고
    • Potential use of TNF-alpha inhibitors in systemic sclerosis
    • COI: 1:CAS:528:DC%2BC2cXmslyhu78%3D, PID: 24762073
    • Murdaca G, Spano F, Contatore M, Guastalla A, Puppo F (2014) Potential use of TNF-alpha inhibitors in systemic sclerosis. Immunotherapy 6:283–289
    • (2014) Immunotherapy , vol.6 , pp. 283-289
    • Murdaca, G.1    Spano, F.2    Contatore, M.3    Guastalla, A.4    Puppo, F.5
  • 75
    • 84891373034 scopus 로고    scopus 로고
    • A20 in inflammation and autoimmunity
    • COI: 1:CAS:528:DC%2BC3sXhsl2jsLbM, PID: 24246475
    • Catrysse L, Vereecke L, Beyaert R, van Loo G (2014) A20 in inflammation and autoimmunity. Trends Immunol 35:22–31
    • (2014) Trends Immunol , vol.35 , pp. 22-31
    • Catrysse, L.1    Vereecke, L.2    Beyaert, R.3    van Loo, G.4
  • 76
    • 77958055758 scopus 로고    scopus 로고
    • Association of the TNFAIP3 rs5029939 variant with systemic sclerosis in the European Caucasian population
    • COI: 1:STN:280:DC%2BC3cbgsVKnsQ%3D%3D, PID: 20511617
    • Dieude P, Guedj M, Wipff J, Ruiz B, Riemekasten G, Matucci-Cerinic M et al (2010) Association of the TNFAIP3 rs5029939 variant with systemic sclerosis in the European Caucasian population. Ann Rheum Dis 69:1958–1964
    • (2010) Ann Rheum Dis , vol.69 , pp. 1958-1964
    • Dieude, P.1    Guedj, M.2    Wipff, J.3    Ruiz, B.4    Riemekasten, G.5    Matucci-Cerinic, M.6
  • 77
    • 84864447493 scopus 로고    scopus 로고
    • Brief report: candidate gene study in systemic sclerosis identifies a rare and functional variant of the TNFAIP3 locus as a risk factor for polyautoimmunity
    • COI: 1:CAS:528:DC%2BC38XhtV2gtb%2FN, PID: 22488580
    • Koumakis E, Giraud M, Dieude P, Cohignac V, Cuomo G, Airo P et al (2012) Brief report: candidate gene study in systemic sclerosis identifies a rare and functional variant of the TNFAIP3 locus as a risk factor for polyautoimmunity. Arthritis Rheum 64:2746–2752
    • (2012) Arthritis Rheum , vol.64 , pp. 2746-2752
    • Koumakis, E.1    Giraud, M.2    Dieude, P.3    Cohignac, V.4    Cuomo, G.5    Airo, P.6
  • 78
    • 84874399330 scopus 로고    scopus 로고
    • Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study
    • COI: 1:CAS:528:DC%2BC3sXnt12rsLk%3D, PID: 22896740
    • Bossini-Castillo L, Martin JE, Broen J, Simeon CP, Beretta L, Gorlova OY et al (2013) Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study. Ann Rheum Dis 72:602–607
    • (2013) Ann Rheum Dis , vol.72 , pp. 602-607
    • Bossini-Castillo, L.1    Martin, J.E.2    Broen, J.3    Simeon, C.P.4    Beretta, L.5    Gorlova, O.Y.6
  • 79
    • 77953724187 scopus 로고    scopus 로고
    • OX40 (CD134) and OX40L
    • COI: 1:CAS:528:DC%2BC3MXhtF2itLvI, PID: 19760068
    • Gough MJ, Weinberg AD (2009) OX40 (CD134) and OX40L. Adv Exp Med Biol 647:94–107
    • (2009) Adv Exp Med Biol , vol.647 , pp. 94-107
    • Gough, M.J.1    Weinberg, A.D.2
  • 80
    • 77955965216 scopus 로고    scopus 로고
    • OX40-OX40 ligand interaction in T-cell-mediated immunity and immunopathology
    • COI: 1:CAS:528:DC%2BC3cXhtFSnurfN, PID: 20510730
    • Ishii N, Takahashi T, Soroosh P, Sugamura K (2010) OX40-OX40 ligand interaction in T-cell-mediated immunity and immunopathology. Adv Immunol 105:63–98
    • (2010) Adv Immunol , vol.105 , pp. 63-98
    • Ishii, N.1    Takahashi, T.2    Soroosh, P.3    Sugamura, K.4
  • 81
    • 77949451240 scopus 로고    scopus 로고
    • Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis
    • COI: 1:CAS:528:DC%2BC3cXksVKgsL4%3D, PID: 19778912
    • Gourh P, Arnett FC, Tan FK, Assassi S, Divecha D, Paz G et al (2010) Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis. Ann Rheum Dis 69:550–555
    • (2010) Ann Rheum Dis , vol.69 , pp. 550-555
    • Gourh, P.1    Arnett, F.C.2    Tan, F.K.3    Assassi, S.4    Divecha, D.5    Paz, G.6
  • 82
    • 79952359835 scopus 로고    scopus 로고
    • A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort
    • COI: 1:CAS:528:DC%2BC3MXkvVyktL4%3D, PID: 21187296
    • Bossini-Castillo L, Broen JC, Simeon CP, Beretta L, Vonk MC, Ortego-Centeno N et al (2011) A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort. Ann Rheum Dis 70:638–641
    • (2011) Ann Rheum Dis , vol.70 , pp. 638-641
    • Bossini-Castillo, L.1    Broen, J.C.2    Simeon, C.P.3    Beretta, L.4    Vonk, M.C.5    Ortego-Centeno, N.6
  • 83
    • 84860741366 scopus 로고    scopus 로고
    • Independent replication and meta analysis of association studies establish TNFSF4 as a susceptibility gene preferentially associated with the subset of anticentromere-positive patients with systemic sclerosis
    • COI: 1:CAS:528:DC%2BC38XhtVeitr%2FE, PID: 22422496
    • Coustet B, Bouaziz M, Dieude P, Guedj M, Bossini-Castillo L, Agarwal S et al (2012) Independent replication and meta analysis of association studies establish TNFSF4 as a susceptibility gene preferentially associated with the subset of anticentromere-positive patients with systemic sclerosis. J Rheum 39:997–1003
    • (2012) J Rheum , vol.39 , pp. 997-1003
    • Coustet, B.1    Bouaziz, M.2    Dieude, P.3    Guedj, M.4    Bossini-Castillo, L.5    Agarwal, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.