메뉴 건너뛰기




Volumn 4, Issue SEP, 2013, Pages

The role of type 1 interferon in systemic sclerosis

Author keywords

IFN inducible cytokines and chemokines; Innate immunity; Interferon regulatory factor; Systemic sclerosis; Type 1 IFN

Indexed keywords


EID: 84886081492     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00266     Document Type: Review
Times cited : (91)

References (102)
  • 1
    • 0035464180 scopus 로고    scopus 로고
    • Immunopathogenesis of scleroderma-evolving concepts
    • Sapadin AN, Esser AC, Fleischmajer R. Immunopathogenesis of scleroderma-evolving concepts. Mt Sinai J Med (2001) 68(4-5):233-42.
    • (2001) Mt Sinai J Med , vol.68 , Issue.4-5 , pp. 233-242
    • Sapadin, A.N.1    Esser, A.C.2    Fleischmajer, R.3
  • 2
    • 0043074631 scopus 로고    scopus 로고
    • Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population
    • doi:10.1002/art.11073
    • Mayes MD, Lacey JV Jr, Beebe-Dimmer J, Gillespie BW, Cooper B, Laing TJ, et al. Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum (2003) 48(8):2246-55. doi:10.1002/art.11073.
    • (2003) Arthritis Rheum , vol.48 , Issue.8 , pp. 2246-2255
    • Mayes, M.D.1    Lacey Jr., J.V.2    Beebe-Dimmer, J.3    Gillespie, B.W.4    Cooper, B.5    Laing, T.J.6
  • 3
    • 84861475814 scopus 로고    scopus 로고
    • Trends in mortality in patients with systemic sclerosis over 40 years: a systematic review and meta-analysis of cohort studies
    • doi:10.1093/rheumatology/ker269
    • Elhai M, Meune C, Avouac J, Kahan A, Allanore Y. Trends in mortality in patients with systemic sclerosis over 40 years: a systematic review and meta-analysis of cohort studies. Rheumatology (Oxford) (2012) 51(6):1017-26. doi:10.1093/rheumatology/ker269.
    • (2012) Rheumatology (Oxford) , vol.51 , Issue.6 , pp. 1017-1026
    • Elhai, M.1    Meune, C.2    Avouac, J.3    Kahan, A.4    Allanore, Y.5
  • 4
    • 0028791799 scopus 로고
    • Interferons: laboratory to clinic investigations
    • doi:10.1097/00001622-199511000-00015
    • Platanias LC. Interferons: laboratory to clinic investigations. Curr Opin Oncol (1995) 7(6):560-5. doi:10.1097/00001622-199511000-00015.
    • (1995) Curr Opin Oncol , vol.7 , Issue.6 , pp. 560-565
    • Platanias, L.C.1
  • 6
    • 0001127173 scopus 로고
    • Quantitative studies on viral interference in suspended L cells. III. Effect of interfering viruses and interferon on the growth rate of cells
    • doi:10.1016/0042-6822(62)90123-X
    • Paucker K, Cantell K, Henle W. Quantitative studies on viral interference in suspended L cells. III. Effect of interfering viruses and interferon on the growth rate of cells. Virology (1962) 17:324-34. doi:10.1016/0042-6822(62)90123-X.
    • (1962) Virology , vol.17 , pp. 324-334
    • Paucker, K.1    Cantell, K.2    Henle, W.3
  • 7
    • 0029048962 scopus 로고
    • Mononuclear cellular infiltrates in clinically involved skin from patients with systemic sclerosis of recent onset predominantly consist of monocytes/macrophages
    • doi:10.1159/000163933
    • Kraling BM, Maul GG, Jimenez SA. Mononuclear cellular infiltrates in clinically involved skin from patients with systemic sclerosis of recent onset predominantly consist of monocytes/macrophages. Pathobiology (1995) 63(1):48-56. doi:10.1159/000163933.
    • (1995) Pathobiology , vol.63 , Issue.1 , pp. 48-56
    • Kraling, B.M.1    Maul, G.G.2    Jimenez, S.A.3
  • 8
    • 0026722319 scopus 로고
    • Macrophage infiltration in the skin of patients with systemic sclerosis
    • Ishikawa O, Ishikawa H. Macrophage infiltration in the skin of patients with systemic sclerosis. J Rheumatol (1992) 19(8):1202-6.
    • (1992) J Rheumatol , vol.19 , Issue.8 , pp. 1202-1206
    • Ishikawa, O.1    Ishikawa, H.2
  • 9
    • 0026604019 scopus 로고
    • Sequential dermal microvascular and perivascular changes in the development of scleroderma
    • doi:10.1002/path.1711660307
    • Prescott RJ, Freemont AJ, Jones CJ, Hoyland J, Fielding P. Sequential dermal microvascular and perivascular changes in the development of scleroderma. J Pathol (1992) 166(3):255-63. doi:10.1002/path.1711660307.
    • (1992) J Pathol , vol.166 , Issue.3 , pp. 255-263
    • Prescott, R.J.1    Freemont, A.J.2    Jones, C.J.3    Hoyland, J.4    Fielding, P.5
  • 10
    • 0021154318 scopus 로고
    • Lymphocytes in the skin of patients with progressive systemic sclerosis. Quantification, subtyping, and clinical correlations
    • doi:10.1002/art.1780270607
    • Roumm AD, Whiteside TL, Medsger TA Jr., Rodnan GP. Lymphocytes in the skin of patients with progressive systemic sclerosis. Quantification, subtyping, and clinical correlations. Arthritis Rheum (1984) 27(6):645-53. doi:10.1002/art.1780270607.
    • (1984) Arthritis Rheum , vol.27 , Issue.6 , pp. 645-653
    • Roumm, A.D.1    Whiteside, T.L.2    Medsger Jr., T.A.3    Rodnan, G.P.4
  • 11
    • 0027464671 scopus 로고
    • Early phenotypic activation of circulating helper memory T cells in scleroderma: correlation with disease activity
    • doi:10.1136/ard.52.4.272
    • Fiocco U, Rosada M, Cozzi L, Ortolani C, De Silvestro G, Ruffatti A, et al. Early phenotypic activation of circulating helper memory T cells in scleroderma: correlation with disease activity. Ann Rheum Dis (1993) 52(4):272-7. doi:10.1136/ard.52.4.272.
    • (1993) Ann Rheum Dis , vol.52 , Issue.4 , pp. 272-277
    • Fiocco, U.1    Rosada, M.2    Cozzi, L.3    Ortolani, C.4    De Silvestro, G.5    Ruffatti, A.6
  • 12
    • 70349572378 scopus 로고    scopus 로고
    • Alternatively activated macrophages (M2 macrophages) in the skin of patient with localized scleroderma
    • doi:10.1111/j.1600-0625.2008.00828.x
    • Higashi-Kuwata N, Makino T, Inoue Y, Takeya M, Ihn H. Alternatively activated macrophages (M2 macrophages) in the skin of patient with localized scleroderma. Exp Dermatol (2009) 18(8):727-9. doi:10.1111/j.1600-0625.2008.00828.x.
    • (2009) Exp Dermatol , vol.18 , Issue.8 , pp. 727-729
    • Higashi-Kuwata, N.1    Makino, T.2    Inoue, Y.3    Takeya, M.4    Ihn, H.5
  • 14
    • 80054728443 scopus 로고    scopus 로고
    • Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis
    • doi:10.1038/ki.2011.217
    • Anders HJ, Ryu M. Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis. Kidney Int (2011) 80(9):915-25. doi:10.1038/ki.2011.217.
    • (2011) Kidney Int , vol.80 , Issue.9 , pp. 915-925
    • Anders, H.J.1    Ryu, M.2
  • 15
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • doi:10.1038/nri978
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol (2003) 3(1):23-35. doi:10.1038/nri978.
    • (2003) Nat Rev Immunol , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 16
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
    • Martinez FO, Gordon S, Locati M, Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol (2006) 177(10):7303-11.
    • (2006) J Immunol , vol.177 , Issue.10 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 17
    • 78651412553 scopus 로고    scopus 로고
    • Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis
    • doi:10.1186/ar3066
    • Higashi-Kuwata N, Jinnin M, Makino T, Fukushima S, Inoue Y, Muchemwa FC, et al. Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis. Arthritis Res Ther (2010) 12(4):R128. doi:10.1186/ar3066.
    • (2010) Arthritis Res Ther , vol.12 , Issue.4
    • Higashi-Kuwata, N.1    Jinnin, M.2    Makino, T.3    Fukushima, S.4    Inoue, Y.5    Muchemwa, F.C.6
  • 18
    • 84857052294 scopus 로고    scopus 로고
    • Serum levels of soluble CD163 in patients with systemic sclerosis
    • doi:10.1007/s00296-010-1691-z
    • Nakayama W, Jinnin M, Makino K, Kajihara I, Makino T, Fukushima S, et al. Serum levels of soluble CD163 in patients with systemic sclerosis. Rheumatol Int (2012) 32(2):403-7. doi:10.1007/s00296-010-1691-z.
    • (2012) Rheumatol Int , vol.32 , Issue.2 , pp. 403-407
    • Nakayama, W.1    Jinnin, M.2    Makino, K.3    Kajihara, I.4    Makino, T.5    Fukushima, S.6
  • 19
    • 84894324140 scopus 로고    scopus 로고
    • Dermal mast cell density in fingers reflects severity of skin sclerosis in systemic sclerosis
    • doi:10.1007/s10165-012-0813-8.
    • Yukawa S, Yamaoka K, Sawamukai N, Shimajiri S, Kubo S, Miyagawa I, et al. Dermal mast cell density in fingers reflects severity of skin sclerosis in systemic sclerosis. Mod Rheumatol (2012):doi:10.1007/s10165-012-0813-8.
    • (2012) Mod Rheumatol
    • Yukawa, S.1    Yamaoka, K.2    Sawamukai, N.3    Shimajiri, S.4    Kubo, S.5    Miyagawa, I.6
  • 20
    • 0034071584 scopus 로고    scopus 로고
    • Mast cells, extracellular matrix components, TGFbeta isoforms and TGFbeta receptor expression in labial salivary glands in systemic sclerosis
    • doi:10.1136/ard.59.3.183
    • Mason GI, Hamburger J, Matthews JB. Mast cells, extracellular matrix components, TGFbeta isoforms and TGFbeta receptor expression in labial salivary glands in systemic sclerosis. Ann Rheum Dis (2000) 59(3):183-9. doi:10.1136/ard.59.3.183.
    • (2000) Ann Rheum Dis , vol.59 , Issue.3 , pp. 183-189
    • Mason, G.I.1    Hamburger, J.2    Matthews, J.B.3
  • 21
    • 79953690825 scopus 로고    scopus 로고
    • Mast cells are a source of transforming growth factor beta in systemic sclerosis
    • doi:10.1002/art.30190
    • Hugle T, Hogan V, White KE, van Laar JM. Mast cells are a source of transforming growth factor beta in systemic sclerosis. Arthritis Rheum (2011) 63(3):795-9. doi:10.1002/art.30190.
    • (2011) Arthritis Rheum , vol.63 , Issue.3 , pp. 795-799
    • Hugle, T.1    Hogan, V.2    White, K.E.3    van Laar, J.M.4
  • 22
    • 0026006233 scopus 로고
    • Human basophil releasability. VIII. Increased basophil releasability in patients with scleroderma
    • doi:10.1002/art.1780341013
    • de Paulis PA, Valentini G, Spadaro G, Lupoli S, Tirri G, Marone G. Human basophil releasability. VIII. Increased basophil releasability in patients with scleroderma. Arthritis Rheum (1991) 34(10):1289-96. doi:10.1002/art.1780341013.
    • (1991) Arthritis Rheum , vol.34 , Issue.10 , pp. 1289-1296
    • de Paulis, P.A.1    Valentini, G.2    Spadaro, G.3    Lupoli, S.4    Tirri, G.5    Marone, G.6
  • 23
    • 13444309109 scopus 로고    scopus 로고
    • Reduced circulating natural killer T cells and gamma/delta T cells in patients with systemic sclerosis
    • Riccieri V, Parisi G, Spadaro A, Scrivo R, Barone F, Moretti T, et al. Reduced circulating natural killer T cells and gamma/delta T cells in patients with systemic sclerosis. J Rheumatol (2005) 32(2):283-6.
    • (2005) J Rheumatol , vol.32 , Issue.2 , pp. 283-286
    • Riccieri, V.1    Parisi, G.2    Spadaro, A.3    Scrivo, R.4    Barone, F.5    Moretti, T.6
  • 24
    • 65549154046 scopus 로고    scopus 로고
    • The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype
    • doi:10.1093/hmg/ddp119
    • Rueda B, Broen J, Simeon C, Hesselstrand R, Diaz B, Suarez H, et al. The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype. Hum Mol Genet (2009) 18(11):2071-7. doi:10.1093/hmg/ddp119.
    • (2009) Hum Mol Genet , vol.18 , Issue.11 , pp. 2071-2077
    • Rueda, B.1    Broen, J.2    Simeon, C.3    Hesselstrand, R.4    Diaz, B.5    Suarez, H.6
  • 25
    • 73249149749 scopus 로고    scopus 로고
    • Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines
    • doi:10.1002/art.24958
    • Gourh P, Agarwal SK, Divecha D, Assassi S, Paz G, Arora-Singh RK, et al. Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines. Arthritis Rheum (2009) 60(12):3794-806. doi:10.1002/art.24958.
    • (2009) Arthritis Rheum , vol.60 , Issue.12 , pp. 3794-3806
    • Gourh, P.1    Agarwal, S.K.2    Divecha, D.3    Assassi, S.4    Paz, G.5    Arora-Singh, R.K.6
  • 26
    • 77951765348 scopus 로고    scopus 로고
    • Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
    • doi:10.1038/ng.565
    • Radstake TR, Gorlova O, Rueda B, Martin JE, Alizadeh BZ, Palomino-Morales R, et al. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet (2010) 42(5):426-9. doi:10.1038/ng.565.
    • (2010) Nat Genet , vol.42 , Issue.5 , pp. 426-429
    • Radstake, T.R.1    Gorlova, O.2    Rueda, B.3    Martin, J.E.4    Alizadeh, B.Z.5    Palomino-Morales, R.6
  • 27
    • 83455173721 scopus 로고    scopus 로고
    • Association study of B-cell marker gene polymorphisms in European caucasian patients with systemic sclerosis
    • Dawidowicz K, Dieude P, Avouac J, WipffJ, Hachulla E, Diot E, et al. Association study of B-cell marker gene polymorphisms in European caucasian patients with systemic sclerosis. Clin Exp Rheumatol (2011) 29(5):839-42.
    • (2011) Clin Exp Rheumatol , vol.29 , Issue.5 , pp. 839-842
    • Dawidowicz, K.1    Dieude, P.2    Avouac, J.3    Wipff, J.4    Hachulla, E.5    Diot, E.6
  • 28
    • 79959856965 scopus 로고    scopus 로고
    • C8orf13-BLK is a genetic risk locus for systemic sclerosis and has additive effects with BANK1: results from a large French cohort and meta-analysis
    • doi:10.1002/art.30379
    • Coustet B, Dieude P, Guedj M, Bouaziz M, Avouac J, Ruiz B, et al. C8orf13-BLK is a genetic risk locus for systemic sclerosis and has additive effects with BANK1: results from a large French cohort and meta-analysis. Arthritis Rheum (2011) 63(7):2091-6. doi:10.1002/art.30379.
    • (2011) Arthritis Rheum , vol.63 , Issue.7 , pp. 2091-2096
    • Coustet, B.1    Dieude, P.2    Guedj, M.3    Bouaziz, M.4    Avouac, J.5    Ruiz, B.6
  • 29
    • 75349113494 scopus 로고    scopus 로고
    • Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations
    • doi:10.1016/j.jaut.2009.08.014
    • Gourh P, Agarwal SK, Martin E, Divecha D, Rueda B, Bunting H, et al. Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations. J Autoimmun (2010) 34(2):155-62. doi:10.1016/j.jaut.2009.08.014.
    • (2010) J Autoimmun , vol.34 , Issue.2 , pp. 155-162
    • Gourh, P.1    Agarwal, S.K.2    Martin, E.3    Divecha, D.4    Rueda, B.5    Bunting, H.6
  • 30
    • 77649114558 scopus 로고    scopus 로고
    • Association of the FAM167A-BLK region with systemic sclerosis
    • doi:10.1002/art.27303
    • Ito I, Kawaguchi Y, Kawasaki A, Hasegawa M, Ohashi J, Kawamoto M, et al. Association of the FAM167A-BLK region with systemic sclerosis. Arthritis Rheum (2010) 62(3):890-5. doi:10.1002/art.27303.
    • (2010) Arthritis Rheum , vol.62 , Issue.3 , pp. 890-895
    • Ito, I.1    Kawaguchi, Y.2    Kawasaki, A.3    Hasegawa, M.4    Ohashi, J.5    Kawamoto, M.6
  • 31
    • 70350521796 scopus 로고    scopus 로고
    • BANK1 is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects with IRF5 and STAT4
    • doi:10.1002/art.24885
    • Dieude P, WipffJ, Guedj M, Ruiz B, Melchers I, Hachulla E, et al. BANK1 is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects with IRF5 and STAT4. Arthritis Rheum (2009) 60(11):3447-54. doi:10.1002/art.24885.
    • (2009) Arthritis Rheum , vol.60 , Issue.11 , pp. 3447-3454
    • Dieude, P.1    Wipff, J.2    Guedj, M.3    Ruiz, B.4    Melchers, I.5    Hachulla, E.6
  • 32
    • 77950315193 scopus 로고    scopus 로고
    • BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in caucasians
    • doi:10.1136/ard.2009.118174
    • Rueda B, Gourh P, Broen J, Agarwal SK, Simeon C, Ortego-Centeno N, et al. BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in caucasians. Ann Rheum Dis (2010) 69(4):700-5. doi:10.1136/ard.2009.118174.
    • (2010) Ann Rheum Dis , vol.69 , Issue.4 , pp. 700-705
    • Rueda, B.1    Gourh, P.2    Broen, J.3    Agarwal, S.K.4    Simeon, C.5    Ortego-Centeno, N.6
  • 33
    • 84862789262 scopus 로고    scopus 로고
    • IRF5 polymorphism predicts prognosis in patients with systemic sclerosis
    • doi:10.1136/annrheumdis-2011-200901
    • Sharif R, Mayes MD, Tan FK, Gorlova OY, Hummers LK, Shah AA, et al. IRF5 polymorphism predicts prognosis in patients with systemic sclerosis. Ann Rheum Dis (2012) 71(7):1197-202. doi:10.1136/annrheumdis-2011-200901.
    • (2012) Ann Rheum Dis , vol.71 , Issue.7 , pp. 1197-1202
    • Sharif, R.1    Mayes, M.D.2    Tan, F.K.3    Gorlova, O.Y.4    Hummers, L.K.5    Shah, A.A.6
  • 34
    • 58249123282 scopus 로고    scopus 로고
    • Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis
    • doi:10.1002/art.24183
    • Dieude P, Guedj M, WipffJ, Avouac J, Fajardy I, Diot E, et al. Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis. Arthritis Rheum (2009) 60(1):225-33. doi:10.1002/art.24183.
    • (2009) Arthritis Rheum , vol.60 , Issue.1 , pp. 225-233
    • Dieude, P.1    Guedj, M.2    Wipff, J.3    Avouac, J.4    Fajardy, I.5    Diot, E.6
  • 35
    • 82955245641 scopus 로고    scopus 로고
    • Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis
    • doi:10.1136/annrheumdis-2011-200275
    • Carmona FD, Gutala R, Simeon CP, Carreira P, Ortego-Centeno N, Vicente-Rabaneda E, et al. Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis. Ann Rheum Dis (2012) 71(1):114-9. doi:10.1136/annrheumdis-2011-200275.
    • (2012) Ann Rheum Dis , vol.71 , Issue.1 , pp. 114-119
    • Carmona, F.D.1    Gutala, R.2    Simeon, C.P.3    Carreira, P.4    Ortego-Centeno, N.5    Vicente-Rabaneda, E.6
  • 36
    • 79960943814 scopus 로고    scopus 로고
    • Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy
    • doi:10.1371/journal.pgen.1002178
    • Gorlova O, Martin JE, Rueda B, Koeleman BP, Ying J, Teruel M, et al. Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. PLoS Genet (2011) 7(7):e1002178. doi:10.1371/journal.pgen.1002178.
    • (2011) PLoS Genet , vol.7 , Issue.7
    • Gorlova, O.1    Martin, J.E.2    Rueda, B.3    Koeleman, B.P.4    Ying, J.5    Teruel, M.6
  • 37
    • 84873830898 scopus 로고    scopus 로고
    • PLD4 as a novel susceptibility gene for systemic sclerosis in a Japanese population
    • doi:10.1002/art.37777
    • Terao C, Ohmura K, Kawaguchi Y, Nishimoto T, Kawasaki A, Takehara K, et al. PLD4 as a novel susceptibility gene for systemic sclerosis in a Japanese population. Arthritis Rheum (2013) 65(2):472-80. doi:10.1002/art.37777.
    • (2013) Arthritis Rheum , vol.65 , Issue.2 , pp. 472-480
    • Terao, C.1    Ohmura, K.2    Kawaguchi, Y.3    Nishimoto, T.4    Kawasaki, A.5    Takehara, K.6
  • 38
    • 84861727232 scopus 로고    scopus 로고
    • Identification of CSK as a systemic sclerosis genetic risk factor through genome wide association study follow-up
    • doi:10.1093/hmg/dds099
    • Martin JE, Broen JC, Carmona FD, Teruel M, Simeon CP, Vonk MC, et al. Identification of CSK as a systemic sclerosis genetic risk factor through genome wide association study follow-up. Hum Mol Genet (2012) 21(12):2825-35. doi:10.1093/hmg/dds099.
    • (2012) Hum Mol Genet , vol.21 , Issue.12 , pp. 2825-2835
    • Martin, J.E.1    Broen, J.C.2    Carmona, F.D.3    Teruel, M.4    Simeon, C.P.5    Vonk, M.C.6
  • 39
    • 77957940944 scopus 로고    scopus 로고
    • Poly(I:C) drives type I IFN-and TGFbeta-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis
    • doi:10.1038/jid.2010.200
    • Farina GA, York MR, Di MM, Collins CA, Meller S, Homey B, et al. Poly(I:C) drives type I IFN-and TGFbeta-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis. J Invest Dermatol (2010) 130(11):2583-93. doi:10.1038/jid.2010.200.
    • (2010) J Invest Dermatol , vol.130 , Issue.11 , pp. 2583-2593
    • Farina, G.A.1    York, M.R.2    Di, M.M.3    Collins, C.A.4    Meller, S.5    Homey, B.6
  • 40
    • 33745625865 scopus 로고    scopus 로고
    • Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients
    • doi:10.1093/rheumatology/kei244
    • Tan FK, Zhou X, Mayes MD, Gourh P, Guo X, Marcum C, et al. Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients. Rheumatology (Oxford) (2006) 45(6):694-702. doi:10.1093/rheumatology/kei244.
    • (2006) Rheumatology (Oxford) , vol.45 , Issue.6 , pp. 694-702
    • Tan, F.K.1    Zhou, X.2    Mayes, M.D.3    Gourh, P.4    Guo, X.5    Marcum, C.6
  • 41
    • 33947154329 scopus 로고    scopus 로고
    • A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type I interferons and toll-like receptor agonists
    • doi:10.1002/art.22382
    • York MR, Nagai T, Mangini AJ, Lemaire R, van Seventer JM, Lafyatis R. A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type I interferons and toll-like receptor agonists. Arthritis Rheum (2007) 56(3):1010-20. doi:10.1002/art.22382.
    • (2007) Arthritis Rheum , vol.56 , Issue.3 , pp. 1010-1020
    • York, M.R.1    Nagai, T.2    Mangini, A.J.3    Lemaire, R.4    van Seventer, J.M.5    Lafyatis, R.6
  • 42
    • 43949127736 scopus 로고    scopus 로고
    • Combined analysis of monocyte and lymphocyte messenger RNA expression with serum protein profiles in patients with scleroderma
    • doi:10.1002/art.23451
    • Duan H, Fleming J, Pritchard DK, Amon LM, Xue J, Arnett HA, et al. Combined analysis of monocyte and lymphocyte messenger RNA expression with serum protein profiles in patients with scleroderma. Arthritis Rheum (2008) 58(5):1465-74. doi:10.1002/art.23451.
    • (2008) Arthritis Rheum , vol.58 , Issue.5 , pp. 1465-1474
    • Duan, H.1    Fleming, J.2    Pritchard, D.K.3    Amon, L.M.4    Xue, J.5    Arnett, H.A.6
  • 43
    • 80053495592 scopus 로고    scopus 로고
    • Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway
    • doi:10.1136/ard.2011.150326
    • Higgs BW, Liu Z, White B, Zhu W, White WI, Morehouse C, et al. Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway. Ann Rheum Dis (2011) 70(11):2029-36. doi:10.1136/ard.2011.150326.
    • (2011) Ann Rheum Dis , vol.70 , Issue.11 , pp. 2029-2036
    • Higgs, B.W.1    Liu, Z.2    White, B.3    Zhu, W.4    White, W.I.5    Morehouse, C.6
  • 44
    • 80053562466 scopus 로고    scopus 로고
    • Safety profile and clinical activity of sifalimumab, a fully human anti-interferon alpha monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study
    • doi:10.1136/ard.2010.144485
    • Merrill JT, Wallace DJ, Petri M, Kirou KA, Yao Y, White WI, et al. Safety profile and clinical activity of sifalimumab, a fully human anti-interferon alpha monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study. Ann Rheum Dis (2011) 70(11):1905-13. doi:10.1136/ard.2010.144485.
    • (2011) Ann Rheum Dis , vol.70 , Issue.11 , pp. 1905-1913
    • Merrill, J.T.1    Wallace, D.J.2    Petri, M.3    Kirou, K.A.4    Yao, Y.5    White, W.I.6
  • 45
    • 84875697484 scopus 로고    scopus 로고
    • Sifalimumab, a human anti-interferon-alpha monoclonal antibody, in systemic lupus erythematosus: a phase I randomized, controlled, dose-escalation study
    • doi:10.1002/art.37824
    • Petri M, Wallace DJ, Spindler A, Chindalore V, Kalunian K, Mysler E, et al. Sifalimumab, a human anti-interferon-alpha monoclonal antibody, in systemic lupus erythematosus: a phase I randomized, controlled, dose-escalation study. Arthritis Rheum (2013) 65(4):1011-21. doi:10.1002/art.37824.
    • (2013) Arthritis Rheum , vol.65 , Issue.4 , pp. 1011-1021
    • Petri, M.1    Wallace, D.J.2    Spindler, A.3    Chindalore, V.4    Kalunian, K.5    Mysler, E.6
  • 46
    • 75749099357 scopus 로고    scopus 로고
    • Systemic sclerosis and lupus: points in an interferon-mediated continuum
    • doi:10.1002/art.27224
    • Assassi S, Mayes MD, Arnett FC, Gourh P, Agarwal SK, McNearney TA, et al. Systemic sclerosis and lupus: points in an interferon-mediated continuum. Arthritis Rheum (2010) 62(2):589-98. doi:10.1002/art.27224.
    • (2010) Arthritis Rheum , vol.62 , Issue.2 , pp. 589-598
    • Assassi, S.1    Mayes, M.D.2    Arnett, F.C.3    Gourh, P.4    Agarwal, S.K.5    McNearney, T.A.6
  • 47
    • 77954965596 scopus 로고    scopus 로고
    • Type I interferon system activation and association with disease manifestations in systemic sclerosis
    • doi:10.1136/ard.2009.121400
    • Eloranta ML, Franck-Larsson K, Lovgren T, Kalamajski S, Ronnblom A, Rubin K, et al. Type I interferon system activation and association with disease manifestations in systemic sclerosis. Ann Rheum Dis (2010) 69(7):1396-402. doi:10.1136/ard.2009.121400.
    • (2010) Ann Rheum Dis , vol.69 , Issue.7 , pp. 1396-1402
    • Eloranta, M.L.1    Franck-Larsson, K.2    Lovgren, T.3    Kalamajski, S.4    Ronnblom, A.5    Rubin, K.6
  • 48
    • 47249144728 scopus 로고    scopus 로고
    • Induction of interferon-alpha by scleroderma sera containing autoantibodies to topoisomerase I: association of higher interferon-alpha activity with lung fibrosis
    • doi:10.1002/art.23486
    • Kim D, Peck A, Santer D, Patole P, Schwartz SM, Molitor JA, et al. Induction of interferon-alpha by scleroderma sera containing autoantibodies to topoisomerase I: association of higher interferon-alpha activity with lung fibrosis. Arthritis Rheum (2008) 58(7):2163-73. doi:10.1002/art.23486.
    • (2008) Arthritis Rheum , vol.58 , Issue.7 , pp. 2163-2173
    • Kim, D.1    Peck, A.2    Santer, D.3    Patole, P.4    Schwartz, S.M.5    Molitor, J.A.6
  • 49
    • 4644349581 scopus 로고    scopus 로고
    • Systemic sclerosis developing in association with the use of interferon alpha therapy for chronic viral hepatitis
    • Solans R, Bosch JA, Esteban I, Vilardell M. Systemic sclerosis developing in association with the use of interferon alpha therapy for chronic viral hepatitis. Clin Exp Rheumatol (2004) 22(5):625-8.
    • (2004) Clin Exp Rheumatol , vol.22 , Issue.5 , pp. 625-628
    • Solans, R.1    Bosch, J.A.2    Esteban, I.3    Vilardell, M.4
  • 50
    • 0032588623 scopus 로고    scopus 로고
    • Interferon-alpha does not improve outcome at one year in patients with diffuse cutaneous scleroderma: results of a randomized, double-blind, placebo-controlled trial
    • doi:10.1002/1529-0131(199902)42:2<299::AID-ANR12>3.0.CO;2-R
    • Black CM, Silman AJ, Herrick AI, Denton CP, Wilson H, Newman J, et al. Interferon-alpha does not improve outcome at one year in patients with diffuse cutaneous scleroderma: results of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum (1999) 42(2):299-305. doi:10.1002/1529-0131(199902)42:2<299::AID-ANR12>3.0.CO;2-R.
    • (1999) Arthritis Rheum , vol.42 , Issue.2 , pp. 299-305
    • Black, C.M.1    Silman, A.J.2    Herrick, A.I.3    Denton, C.P.4    Wilson, H.5    Newman, J.6
  • 51
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • doi:10.1016/j.cell.2006.02.015
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell (2006) 124(4):783-801. doi:10.1016/j.cell.2006.02.015.
    • (2006) Cell , vol.124 , Issue.4 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 52
    • 33745034931 scopus 로고    scopus 로고
    • Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies
    • doi:10.1002/art.21890
    • Hua J, Kirou K, Lee C, Crow MK. Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies. Arthritis Rheum (2006) 54(6):1906-16. doi:10.1002/art.21890.
    • (2006) Arthritis Rheum , vol.54 , Issue.6 , pp. 1906-1916
    • Hua, J.1    Kirou, K.2    Lee, C.3    Crow, M.K.4
  • 53
    • 34249712937 scopus 로고    scopus 로고
    • Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: assignment of a type I interferon signature in a subpopulation of patients
    • doi:10.1136/ard.2006.063412
    • Van der Pouw Kraan TC, Wijbrandts CA, van Baarsen LG, Voskuyl AE, Rustenburg F, Baggen JM, et al. Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: assignment of a type I interferon signature in a subpopulation of patients. Ann Rheum Dis (2007) 66(8):1008-14. doi:10.1136/ard.2006.063412.
    • (2007) Ann Rheum Dis , vol.66 , Issue.8 , pp. 1008-1014
    • Van der Pouw Kraan, T.C.1    Wijbrandts, C.A.2    van Baarsen, L.G.3    Voskuyl, A.E.4    Rustenburg, F.5    Baggen, J.M.6
  • 54
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on toll-like receptors
    • doi:10.1038/ni.1863
    • Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on toll-like receptors. Nat Immunol (2010) 11(5):373-84. doi:10.1038/ni.1863.
    • (2010) Nat Immunol , vol.11 , Issue.5 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 55
    • 84871284466 scopus 로고    scopus 로고
    • Toll-like receptor 4 signaling augments transforming growth factor-beta responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma
    • doi:10.1016/j.ajpath.2012.09.007
    • Bhattacharyya S, Kelley K, Melichian DS, Tamaki Z, Fang F, Su Y, et al. Toll-like receptor 4 signaling augments transforming growth factor-beta responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma. Am J Pathol (2013) 182(1):192-205. doi:10.1016/j.ajpath.2012.09.007.
    • (2013) Am J Pathol , vol.182 , Issue.1 , pp. 192-205
    • Bhattacharyya, S.1    Kelley, K.2    Melichian, D.S.3    Tamaki, Z.4    Fang, F.5    Su, Y.6
  • 56
    • 78651068822 scopus 로고    scopus 로고
    • Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts
    • doi:10.1186/ar3221
    • Agarwal SK, Wu M, Livingston CK, Parks DH, Mayes MD, Arnett FC, et al. Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts. Arthritis Res Ther (2011) 13(1):R3. doi:10.1186/ar3221.
    • (2011) Arthritis Res Ther , vol.13 , Issue.1
    • Agarwal, S.K.1    Wu, M.2    Livingston, C.K.3    Parks, D.H.4    Mayes, M.D.5    Arnett, F.C.6
  • 57
    • 42649114059 scopus 로고    scopus 로고
    • The IRF family transcription factors in immunity and oncogenesis
    • doi:10.1146/annurev.immunol.26.021607.090400
    • Tamura T, Yanai H, Savitsky D, Taniguchi T. The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol (2008) 26:535-84. doi:10.1146/annurev.immunol.26.021607.090400.
    • (2008) Annu Rev Immunol , vol.26 , pp. 535-584
    • Tamura, T.1    Yanai, H.2    Savitsky, D.3    Taniguchi, T.4
  • 58
    • 0032841028 scopus 로고    scopus 로고
    • Interferon regulatory factors: the next generation
    • doi:10.1016/S0378-1119(99)00262-0
    • Mamane Y, Heylbroeck C, Genin P, Algarte M, Servant MJ, LePage C, et al. Interferon regulatory factors: the next generation. Gene (1999) 237(1):1-14. doi:10.1016/S0378-1119(99)00262-0.
    • (1999) Gene , vol.237 , Issue.1 , pp. 1-14
    • Mamane, Y.1    Heylbroeck, C.2    Genin, P.3    Algarte, M.4    Servant, M.J.5    LePage, C.6
  • 59
    • 0035061538 scopus 로고    scopus 로고
    • IRF family of transcription factors as regulators of host defense
    • doi:10.1146/annurev.immunol.19.1.623
    • Taniguchi T, Ogasawara K, Takaoka A, Tanaka N. IRF family of transcription factors as regulators of host defense. Annu Rev Immunol (2001) 19:623-55. doi:10.1146/annurev.immunol.19.1.623.
    • (2001) Annu Rev Immunol , vol.19 , pp. 623-655
    • Taniguchi, T.1    Ogasawara, K.2    Takaoka, A.3    Tanaka, N.4
  • 60
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I-and type-II-interferon-mediated signalling
    • doi:10.1038/nri1604
    • Platanias LC. Mechanisms of type-I-and type-II-interferon-mediated signalling. Nat Rev Immunol (2005) 5(5):375-86. doi:10.1038/nri1604.
    • (2005) Nat Rev Immunol , vol.5 , Issue.5 , pp. 375-386
    • Platanias, L.C.1
  • 61
    • 25444495693 scopus 로고    scopus 로고
    • The yin and yang of type I interferon activity in bacterial infection
    • doi:10.1038/nri1684
    • Decker T, Muller M, Stockinger S. The yin and yang of type I interferon activity in bacterial infection. Nat Rev Immunol (2005) 5(9):675-87. doi:10.1038/nri1684.
    • (2005) Nat Rev Immunol , vol.5 , Issue.9 , pp. 675-687
    • Decker, T.1    Muller, M.2    Stockinger, S.3
  • 62
    • 7244242345 scopus 로고    scopus 로고
    • Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection
    • doi:10.1074/jbc. M400726200
    • Barnes BJ, Richards J, Mancl M, Hanash S, Beretta L, Pitha PM. Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection. J Biol Chem (2004) 279(43):45194-207. doi:10.1074/jbc. M400726200.
    • (2004) J Biol Chem , vol.279 , Issue.43 , pp. 45194-207
    • Barnes, B.J.1    Richards, J.2    Mancl, M.3    Hanash, S.4    Beretta, L.5    Pitha, P.M.6
  • 63
    • 0141919557 scopus 로고    scopus 로고
    • Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death
    • Barnes BJ, Kellum MJ, Pinder KE, Frisancho JA, Pitha PM. Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death. Cancer Res (2003) 63(19):6424-31.
    • (2003) Cancer Res , vol.63 , Issue.19 , pp. 6424-6431
    • Barnes, B.J.1    Kellum, M.J.2    Pinder, K.E.3    Frisancho, J.A.4    Pitha, P.M.5
  • 64
    • 0035968246 scopus 로고    scopus 로고
    • Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes
    • doi:10.1074/jbc. M101216200
    • Barnes BJ, Moore PA, Pitha PM. Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. J Biol Chem (2001) 276(26):23382-90. doi:10.1074/jbc. M101216200.
    • (2001) J Biol Chem , vol.276 , Issue.26 , pp. 23382-90
    • Barnes, B.J.1    Moore, P.A.2    Pitha, P.M.3
  • 65
    • 33748051738 scopus 로고    scopus 로고
    • IRFs: master regulators of signalling by toll-like receptors and cytosolic pattern-recognition receptors
    • doi:10.1038/nri1900
    • Honda K, Taniguchi T. IRFs: master regulators of signalling by toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol (2006) 6(9):644-58. doi:10.1038/nri1900.
    • (2006) Nat Rev Immunol , vol.6 , Issue.9 , pp. 644-658
    • Honda, K.1    Taniguchi, T.2
  • 66
    • 15044345461 scopus 로고    scopus 로고
    • Integral role of IRF-5 in the gene induction programme activated by toll-like receptors
    • doi:10.1038/nature03308
    • Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, et al. Integral role of IRF-5 in the gene induction programme activated by toll-like receptors. Nature (2005) 434(7030):243-9. doi:10.1038/nature03308.
    • (2005) Nature , vol.434 , Issue.7030 , pp. 243-249
    • Takaoka, A.1    Yanai, H.2    Kondo, S.3    Duncan, G.4    Negishi, H.5    Mizutani, T.6
  • 67
    • 68049112537 scopus 로고    scopus 로고
    • STAT4 is a genetic risk factor for systemic sclerosis having additive effects with IRF5 on disease susceptibility and related pulmonary fibrosis
    • doi:10.1002/art.24688
    • Dieude P, Guedj M, WipffJ, Ruiz B, Hachulla E, Diot E, et al. STAT4 is a genetic risk factor for systemic sclerosis having additive effects with IRF5 on disease susceptibility and related pulmonary fibrosis. Arthritis Rheum (2009) 60(8):2472-9. doi:10.1002/art.24688.
    • (2009) Arthritis Rheum , vol.60 , Issue.8 , pp. 2472-2479
    • Dieude, P.1    Guedj, M.2    Wipff, J.3    Ruiz, B.4    Hachulla, E.5    Diot, E.6
  • 68
    • 66449100302 scopus 로고    scopus 로고
    • Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population
    • doi:10.1002/art.24600
    • Ito I, Kawaguchi Y, Kawasaki A, Hasegawa M, Ohashi J, Hikami K, et al. Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population. Arthritis Rheum (2009) 60(6):1845-50. doi:10.1002/art.24600.
    • (2009) Arthritis Rheum , vol.60 , Issue.6 , pp. 1845-1850
    • Ito, I.1    Kawaguchi, Y.2    Kawasaki, A.3    Hasegawa, M.4    Ohashi, J.5    Hikami, K.6
  • 69
    • 77951792926 scopus 로고    scopus 로고
    • Phenotype-haplotype correlation of IRF5 in systemic sclerosis: role of 2 haplotypes in disease severity
    • doi:10.3899/jrheum.091163
    • Dieude P, Dawidowicz K, Guedj M, Legrain Y, WipffJ, Hachulla E, et al. Phenotype-haplotype correlation of IRF5 in systemic sclerosis: role of 2 haplotypes in disease severity. J Rheumatol (2010) 37(5):987-92. doi:10.3899/jrheum.091163.
    • (2010) J Rheumatol , vol.37 , Issue.5 , pp. 987-992
    • Dieude, P.1    Dawidowicz, K.2    Guedj, M.3    Legrain, Y.4    Wipff, J.5    Hachulla, E.6
  • 70
    • 77956329223 scopus 로고    scopus 로고
    • Murine toll-like receptor 2 activation induces type I interferon responses from endolysosomal compartments
    • doi:10.1371/journal.pone.0010250
    • Dietrich N, Lienenklaus S, Weiss S, Gekara NO. Murine toll-like receptor 2 activation induces type I interferon responses from endolysosomal compartments. PLoS One (2010) 5(4):e10250. doi:10.1371/journal.pone.0010250.
    • (2010) PLoS One , vol.5 , Issue.4
    • Dietrich, N.1    Lienenklaus, S.2    Weiss, S.3    Gekara, N.O.4
  • 71
    • 0034948757 scopus 로고    scopus 로고
    • The interferon system and interferon regulatory factor transcription factors-studies from gene knockout mice
    • doi:10.1016/S1359-6101(00)00032-0
    • Sato M, Taniguchi T, Tanaka N. The interferon system and interferon regulatory factor transcription factors-studies from gene knockout mice. Cytokine Growth Factor Rev (2001) 12(2-3):133-42. doi:10.1016/S1359-6101(00)00032-0.
    • (2001) Cytokine Growth Factor Rev , vol.12 , Issue.2-3 , pp. 133-142
    • Sato, M.1    Taniguchi, T.2    Tanaka, N.3
  • 72
    • 17144404177 scopus 로고    scopus 로고
    • IRF-7 is the master regulator of type-I interferon-dependent immune responses
    • doi:10.1038/nature03464
    • Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature (2005) 434(7034):772-7. doi:10.1038/nature03464.
    • (2005) Nature , vol.434 , Issue.7034 , pp. 772-777
    • Honda, K.1    Yanai, H.2    Negishi, H.3    Asagiri, M.4    Sato, M.5    Mizutani, T.6
  • 73
    • 0032015647 scopus 로고    scopus 로고
    • Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo
    • doi:10.1016/S1097-2765(00)80051-9
    • Wathelet MG, Lin CH, Parekh BS, Ronco LV, Howley PM, Maniatis T. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell (1998) 1(4):507-18. doi:10.1016/S1097-2765(00)80051-9.
    • (1998) Mol Cell , vol.1 , Issue.4 , pp. 507-518
    • Wathelet, M.G.1    Lin, C.H.2    Parekh, B.S.3    Ronco, L.V.4    Howley, P.M.5    Maniatis, T.6
  • 74
    • 0037844850 scopus 로고    scopus 로고
    • Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators
    • doi:10.1074/jbc. M212940200
    • Yang H, Lin CH, Ma G, BaffiMO, Wathelet MG. Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators. J Biol Chem (2003) 278(18):15495-504. doi:10.1074/jbc. M212940200.
    • (2003) J Biol Chem , vol.278 , Issue.18 , pp. 15495-504
    • Yang, H.1    Lin, C.H.2    Ma, G.3    Baffi, M.O.4    Wathelet, M.G.5
  • 75
    • 34249792362 scopus 로고    scopus 로고
    • Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF)5 and IRF7 dependent and is required for IL-6 production
    • Yasuda K, Richez C, Maciaszek JW, Agrawal N, Akira S, Marshak-Rothstein A, et al. Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF)5 and IRF7 dependent and is required for IL-6 production. J Immunol (2007) 178(11):6876-85.
    • (2007) J Immunol , vol.178 , Issue.11 , pp. 6876-6885
    • Yasuda, K.1    Richez, C.2    Maciaszek, J.W.3    Agrawal, N.4    Akira, S.5    Marshak-Rothstein, A.6
  • 76
    • 80054048063 scopus 로고    scopus 로고
    • Targeting interferon regulatory factors to inhibit activation of the type I IFN response: implications for treatment of autoimmune disorders
    • doi:10.1016/j.cellimm.2011.07.014
    • Sweeney SE. Targeting interferon regulatory factors to inhibit activation of the type I IFN response: implications for treatment of autoimmune disorders. Cell Immunol (2011) 271(2):342-9. doi:10.1016/j.cellimm.2011.07.014.
    • (2011) Cell Immunol , vol.271 , Issue.2 , pp. 342-349
    • Sweeney, S.E.1
  • 77
    • 38649125210 scopus 로고    scopus 로고
    • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    • doi:10.1038/ng.81
    • Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet (2008) 40(2):204-10. doi:10.1038/ng.81.
    • (2008) Nat Genet , vol.40 , Issue.2 , pp. 204-210
    • Harley, J.B.1    Alarcon-Riquelme, M.E.2    Criswell, L.A.3    Jacob, C.O.4    Kimberly, R.P.5    Moser, K.L.6
  • 78
    • 84861806223 scopus 로고    scopus 로고
    • Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese population
    • doi:10.1177/0961203312439333
    • Kawasaki A, Furukawa H, Kondo Y, Ito S, Hayashi T, Kusaoi M, et al. Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese population. Lupus (2012) 21(8):890-5. doi:10.1177/0961203312439333.
    • (2012) Lupus , vol.21 , Issue.8 , pp. 890-895
    • Kawasaki, A.1    Furukawa, H.2    Kondo, Y.3    Ito, S.4    Hayashi, T.5    Kusaoi, M.6
  • 79
    • 80052328859 scopus 로고    scopus 로고
    • The potential role of interferon-regulatory factor 7 among Taiwanese patients with systemic lupus erythematosus
    • doi:10.3899/jrheum.101004
    • Lin LH, Ling P, Liu MF. The potential role of interferon-regulatory factor 7 among Taiwanese patients with systemic lupus erythematosus. J Rheumatol (2011) 38(9):1914-9. doi:10.3899/jrheum.101004.
    • (2011) J Rheumatol , vol.38 , Issue.9 , pp. 1914-1919
    • Lin, L.H.1    Ling, P.2    Liu, M.F.3
  • 80
    • 79953707345 scopus 로고    scopus 로고
    • Association of a functional IRF7 variant with systemic lupus erythematosus
    • doi:10.1002/art.30193
    • Fu Q, Zhao J, Qian X, Wong JL, Kaufman KM, Yu CY, et al. Association of a functional IRF7 variant with systemic lupus erythematosus. Arthritis Rheum (2011) 63(3):749-54. doi:10.1002/art.30193.
    • (2011) Arthritis Rheum , vol.63 , Issue.3 , pp. 749-754
    • Fu, Q.1    Zhao, J.2    Qian, X.3    Wong, J.L.4    Kaufman, K.M.5    Yu, C.Y.6
  • 81
    • 84855289550 scopus 로고    scopus 로고
    • Basal activation of type I interferons (alpha2 and beta) and 2'5'OAS genes: insights into differential expression profiles of interferon system components in systemic sclerosis
    • doi:10.1155/2011/275617
    • De Oliveira DB, Almeida GM, Guedes AC, Santos FP, Bonjardim CA, Ferreira PC, et al. Basal activation of type I interferons (alpha2 and beta) and 2'5'OAS genes: insights into differential expression profiles of interferon system components in systemic sclerosis. Int J Rheumatol (2011) 2011:275617. doi:10.1155/2011/275617.
    • (2011) Int J Rheumatol , vol.2011 , pp. 275617
    • De Oliveira, D.B.1    Almeida, G.M.2    Guedes, A.C.3    Santos, F.P.4    Bonjardim, C.A.5    Ferreira, P.C.6
  • 82
    • 33744539146 scopus 로고    scopus 로고
    • IRF-8/interferon (IFN) consensus sequence-binding protein is involved in toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways
    • doi:10.1074/jbc. M507788200
    • Zhao J, Kong HJ, Li H, Huang B, Yang M, Zhu C, et al. IRF-8/interferon (IFN) consensus sequence-binding protein is involved in toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. J Biol Chem (2006) 281(15):10073-80. doi:10.1074/jbc. M507788200.
    • (2006) J Biol Chem , vol.281 , Issue.15 , pp. 10073-80
    • Zhao, J.1    Kong, H.J.2    Li, H.3    Huang, B.4    Yang, M.5    Zhu, C.6
  • 83
    • 34548035397 scopus 로고    scopus 로고
    • The feedback phase of type I interferon induction in dendritic cells requires interferon regulatory factor 8
    • doi:10.1016/j.immuni.2007.06.009
    • Tailor P, Tamura T, Kong HJ, Kubota T, Kubota M, Borghi P, et al. The feedback phase of type I interferon induction in dendritic cells requires interferon regulatory factor 8. Immunity (2007) 27(2):228-39. doi:10.1016/j.immuni.2007.06.009.
    • (2007) Immunity , vol.27 , Issue.2 , pp. 228-239
    • Tailor, P.1    Tamura, T.2    Kong, H.J.3    Kubota, T.4    Kubota, M.5    Borghi, P.6
  • 85
    • 0038506030 scopus 로고    scopus 로고
    • IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development
    • doi:10.1101/gad.1104803
    • Lu R, Medina KL, Lancki DW, Singh H. IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev (2003) 17(14):1703-8. doi:10.1101/gad.1104803.
    • (2003) Genes Dev , vol.17 , Issue.14 , pp. 1703-1708
    • Lu, R.1    Medina, K.L.2    Lancki, D.W.3    Singh, H.4
  • 87
    • 59649109772 scopus 로고    scopus 로고
    • B cell depletion with rituximab in patients with diffuse cutaneous systemic sclerosis
    • doi:10.1002/art.24249
    • Lafyatis R, Kissin E, York M, Farina G, Viger K, Fritzler MJ, et al. B cell depletion with rituximab in patients with diffuse cutaneous systemic sclerosis. Arthritis Rheum (2009) 60(2):578-83. doi:10.1002/art.24249.
    • (2009) Arthritis Rheum , vol.60 , Issue.2 , pp. 578-583
    • Lafyatis, R.1    Kissin, E.2    York, M.3    Farina, G.4    Viger, K.5    Fritzler, M.J.6
  • 88
    • 73449095775 scopus 로고    scopus 로고
    • Rituximab in diffuse cutaneous systemic sclerosis: an open-label clinical and histopathological study
    • doi:10.1136/ard.2008.095463
    • Smith V, Van Praet JT, Vandooren B, Van der Cruyssen B, Naeyaert JM, Decuman S, et al. Rituximab in diffuse cutaneous systemic sclerosis: an open-label clinical and histopathological study. Ann Rheum Dis (2010) 69(1):193-7. doi:10.1136/ard.2008.095463.
    • (2010) Ann Rheum Dis , vol.69 , Issue.1 , pp. 193-197
    • Smith, V.1    Van Praet, J.T.2    Vandooren, B.3    Van der Cruyssen, B.4    Naeyaert, J.M.5    Decuman, S.6
  • 89
    • 84867200145 scopus 로고    scopus 로고
    • The IL-6 promoter polymorphism is associated with disease activity and disability in systemic sclerosis
    • doi:10.2755/jcmm010.004.08
    • Sfrent-Cornateanu R, Mihai C, Balan S, Ionescu R, Moldoveanu E. The IL-6 promoter polymorphism is associated with disease activity and disability in systemic sclerosis. J Cell Mol Med (2006) 10(4):955-9. doi:10.2755/jcmm010.004.08.
    • (2006) J Cell Mol Med , vol.10 , Issue.4 , pp. 955-959
    • Sfrent-Cornateanu, R.1    Mihai, C.2    Balan, S.3    Ionescu, R.4    Moldoveanu, E.5
  • 90
    • 83655164152 scopus 로고    scopus 로고
    • The association between interleukin-6 polymorphisms and systemic lupus erythematosus: a meta-analysis
    • doi:10.1177/0961203311422711
    • Lee YH, Lee HS, Choi SJ, Ji JD, Song GG. The association between interleukin-6 polymorphisms and systemic lupus erythematosus: a meta-analysis. Lupus (2012) 21(1):60-7. doi:10.1177/0961203311422711.
    • (2012) Lupus , vol.21 , Issue.1 , pp. 60-67
    • Lee, Y.H.1    Lee, H.S.2    Choi, S.J.3    Ji, J.D.4    Song, G.G.5
  • 91
    • 0027518860 scopus 로고
    • Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity
    • doi:10.1136/ard.52.3.232
    • Madhok R, Crilly A, Watson J, Capell HA. Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity. Ann Rheum Dis (1993) 52(3):232-4. doi:10.1136/ard.52.3.232.
    • (1993) Ann Rheum Dis , vol.52 , Issue.3 , pp. 232-234
    • Madhok, R.1    Crilly, A.2    Watson, J.3    Capell, H.A.4
  • 92
    • 0024155507 scopus 로고
    • Molecular regulation of B lymphocyte response
    • doi:10.1146/annurev.iy.06.040188.002413
    • Kishimoto T, Hirano T. Molecular regulation of B lymphocyte response. Annu Rev Immunol (1988) 6:485-512. doi:10.1146/annurev.iy.06.040188.002413.
    • (1988) Annu Rev Immunol , vol.6 , pp. 485-512
    • Kishimoto, T.1    Hirano, T.2
  • 93
    • 0026333033 scopus 로고
    • Interleukin-6 and its relation to inflammation and disease
    • doi:10.1016/0090-1229(92)90042-M
    • Hirano T. Interleukin-6 and its relation to inflammation and disease. Clin Immunol Immunopathol (1992) 62(1 Pt 2):S60-5. doi:10.1016/0090-1229(92)90042-M.
    • (1992) Clin Immunol Immunopathol , vol.62 , Issue.1 PART 2
    • Hirano, T.1
  • 94
    • 4143119932 scopus 로고    scopus 로고
    • Enhanced airway inflammation and decreased subepithelial fibrosis in interleukin 6-deficient mice following chronic exposure to aerosolized antigen
    • doi:10.1111/j.1365-2222.2004.02013.x
    • Qiu Z, Fujimura M, Kurashima K, Nakao S, Mukaida N. Enhanced airway inflammation and decreased subepithelial fibrosis in interleukin 6-deficient mice following chronic exposure to aerosolized antigen. Clin Exp Allergy (2004) 34(8):1321-8. doi:10.1111/j.1365-2222.2004.02013.x.
    • (2004) Clin Exp Allergy , vol.34 , Issue.8 , pp. 1321-1328
    • Qiu, Z.1    Fujimura, M.2    Kurashima, K.3    Nakao, S.4    Mukaida, N.5
  • 95
    • 42949157763 scopus 로고    scopus 로고
    • Role of interleukin-6 in bleomycin-induced lung inflammatory changes in mice
    • doi:10.1165/rcmb.2007-0299OC
    • Saito F, Tasaka S, Inoue K, Miyamoto K, Nakano Y, Ogawa Y, et al. Role of interleukin-6 in bleomycin-induced lung inflammatory changes in mice. Am J Respir Cell Mol Biol (2008) 38(5):566-71. doi:10.1165/rcmb.2007-0299OC.
    • (2008) Am J Respir Cell Mol Biol , vol.38 , Issue.5 , pp. 566-571
    • Saito, F.1    Tasaka, S.2    Inoue, K.3    Miyamoto, K.4    Nakano, Y.5    Ogawa, Y.6
  • 96
    • 0032746822 scopus 로고    scopus 로고
    • Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis
    • doi:10.1093/rheumatology/38.7.612
    • Hasegawa M, Sato S, Ihn H, Takehara K. Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis. Rheumatology (Oxford) (1999) 38(7):612-7. doi:10.1093/rheumatology/38.7.612.
    • (1999) Rheumatology (Oxford) , vol.38 , Issue.7 , pp. 612-617
    • Hasegawa, M.1    Sato, S.2    Ihn, H.3    Takehara, K.4
  • 97
    • 84875861264 scopus 로고    scopus 로고
    • Serum interleukin 6 is predictive of early functional decline and mortality in interstitial lung disease associated with systemic sclerosis
    • doi:10.3899/jrheum.120725
    • De Lauretis A, Sestini P, Pantelidis P, Hoyles R, Hansell DM, Goh NS, et al. Serum interleukin 6 is predictive of early functional decline and mortality in interstitial lung disease associated with systemic sclerosis. J Rheumatol (2013) 40(4):435-46. doi:10.3899/jrheum.120725.
    • (2013) J Rheumatol , vol.40 , Issue.4 , pp. 435-446
    • De Lauretis, A.1    Sestini, P.2    Pantelidis, P.3    Hoyles, R.4    Hansell, D.M.5    Goh, N.S.6
  • 98
    • 34548125310 scopus 로고    scopus 로고
    • T(H)-17 differentiation: of mice and men
    • doi:10.1038/ni0907-903
    • Laurence A, O'Shea JJ. T(H)-17 differentiation: of mice and men. Nat Immunol (2007) 8(9):903-5. doi:10.1038/ni0907-903.
    • (2007) Nat Immunol , vol.8 , Issue.9 , pp. 903-905
    • Laurence, A.1    O'Shea, J.J.2
  • 99
    • 0034661356 scopus 로고    scopus 로고
    • Lineage commitment in the immune system: the T helper lymphocyte grows up
    • Glimcher LH, Murphy KM. Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes Dev (2000) 14(14):1693-711.
    • (2000) Genes Dev , vol.14 , Issue.14 , pp. 1693-1711
    • Glimcher, L.H.1    Murphy, K.M.2
  • 100
    • 0035925040 scopus 로고    scopus 로고
    • Establishment and characterization of a human B cell line from the lung tissue of a patient with scleroderma; extraordinary high level of IL-6 secretion by stimulated fibroblasts
    • doi:10.1006/cyto.2000.0822
    • Kondo K, Okada T, Matsui T, Kato S, Date K, Yoshihara M, et al. Establishment and characterization of a human B cell line from the lung tissue of a patient with scleroderma; extraordinary high level of IL-6 secretion by stimulated fibroblasts. Cytokine (2001) 13(4):220-6. doi:10.1006/cyto.2000.0822.
    • (2001) Cytokine , vol.13 , Issue.4 , pp. 220-226
    • Kondo, K.1    Okada, T.2    Matsui, T.3    Kato, S.4    Date, K.5    Yoshihara, M.6
  • 101
    • 0025989368 scopus 로고
    • Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6
    • doi:10.1111/1523-1747.ep12483971
    • Duncan MR, Berman B. Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6. J Invest Dermatol (1991) 97(4):686-92. doi:10.1111/1523-1747.ep12483971.
    • (1991) J Invest Dermatol , vol.97 , Issue.4 , pp. 686-692
    • Duncan, M.R.1    Berman, B.2
  • 102
    • 84871784398 scopus 로고    scopus 로고
    • Correlation of interferon-inducible chemokine plasma levels with disease severity in systemic sclerosis
    • doi:10.1002/art.37742
    • Liu X, Mayes MD, Tan FK, Wu M, Reveille JD, Harper BE, et al. Correlation of interferon-inducible chemokine plasma levels with disease severity in systemic sclerosis. Arthritis Rheum (2013) 65(1):226-35. doi:10.1002/art.37742.
    • (2013) Arthritis Rheum , vol.65 , Issue.1 , pp. 226-235
    • Liu, X.1    Mayes, M.D.2    Tan, F.K.3    Wu, M.4    Reveille, J.D.5    Harper, B.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.