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Volumn 4, Issue APR, 2013, Pages

Autophagy and autoimmunity crosstalks

Author keywords

Autoimmune; Autoimmunity; Autophagosome; Autophagy; Encephalomyelitis; Experimental; Lupus erythematosus; Systemic

Indexed keywords

ALPHA INTERFERON; AUTOPHAGY PROTEIN 5; BECLIN 1; INTERLEUKIN 1BETA; LYSOPHOSPHATIDYLCHOLINE; MAMMALIAN TARGET OF RAPAMYCIN;

EID: 84883717351     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00088     Document Type: Article
Times cited : (62)

References (92)
  • 1
    • 84874565064 scopus 로고    scopus 로고
    • Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance
    • Aichinger, M., Wu, C., Nedjic, J., and Klein, L. (2013). Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance. J. Exp. Med. 210, 287-300.
    • (2013) J. Exp. Med. , vol.210 , pp. 287-300
    • Aichinger, M.1    Wu, C.2    Nedjic, J.3    Klein, L.4
  • 2
    • 61649092566 scopus 로고    scopus 로고
    • Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis
    • Alirezaei, M., Fox, H. S., Flynn, C. T., Moore, C. S., Hebb, A. L., Frausto, R. F., et al. (2009). Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis. Autophagy 5, 152-158.
    • (2009) Autophagy , vol.5 , pp. 152-158
    • Alirezaei, M.1    Fox, H.S.2    Flynn, C.T.3    Moore, C.S.4    Hebb, A.L.5    Frausto, R.F.6
  • 6
    • 81855167104 scopus 로고    scopus 로고
    • Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
    • Berer, K., Mues, M., Koutrolos, M., Rasbi, Z. A., Boziki, M., Johner, C., et al. (2011). Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 479, 538-541.
    • (2011) Nature , vol.479 , pp. 538-541
    • Berer, K.1    Mues, M.2    Koutrolos, M.3    Rasbi, Z.A.4    Boziki, M.5    Johner, C.6
  • 7
    • 56249135538 scopus 로고    scopus 로고
    • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
    • Cadwell, K., Liu, J. Y., Brown, S. L., Miyoshi, H., Loh, J., Lennerz, J. K., et al. (2008). A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 456, 259-263.
    • (2008) Nature , vol.456 , pp. 259-263
    • Cadwell, K.1    Liu, J.Y.2    Brown, S.L.3    Miyoshi, H.4    Loh, J.5    Lennerz, J.K.6
  • 8
    • 52549127241 scopus 로고    scopus 로고
    • Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
    • Cao, W., Manicassamy, S., Tang, H., Kasturi, S. P., Pirani, A., Murthy, N., et al. (2008). Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nat. Immunol. 9, 1157-1164.
    • (2008) Nat. Immunol. , vol.9 , pp. 1157-1164
    • Cao, W.1    Manicassamy, S.2    Tang, H.3    Kasturi, S.P.4    Pirani, A.5    Murthy, N.6
  • 9
    • 44649161194 scopus 로고    scopus 로고
    • The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens
    • Chaturvedi, A., Dorward, D., and Pierce, S. K. (2008). The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens. Immunity 28, 799-809.
    • (2008) Immunity , vol.28 , pp. 799-809
    • Chaturvedi, A.1    Dorward, D.2    Pierce, S.K.3
  • 10
    • 64049089798 scopus 로고    scopus 로고
    • Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
    • Chung, Y., Chang, S. H., Martinez, G. J., Yang, X. O., Nurieva, R., Kang, H. S., et al. (2009). Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 30, 576-587.
    • (2009) Immunity , vol.30 , pp. 576-587
    • Chung, Y.1    Chang, S.H.2    Martinez, G.J.3    Yang, X.O.4    Nurieva, R.5    Kang, H.S.6
  • 11
    • 73849151394 scopus 로고    scopus 로고
    • NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
    • Cooney, R., Baker, J., Brain, O., Danis, B., Pichulik, T., Allan, P., et al. (2010). NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat. Med. 16, 90-97.
    • (2010) Nat. Med. , vol.16 , pp. 90-97
    • Cooney, R.1    Baker, J.2    Brain, O.3    Danis, B.4    Pichulik, T.5    Allan, P.6
  • 12
    • 20344361954 scopus 로고    scopus 로고
    • Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
    • Dengjel, J., Schoor, O., Fischer, R., Reich, M., Kraus, M., Muller, M., et al. (2005). Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc. Natl. Acad. Sci. U.S.A. 102, 7922-7927.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 7922-7927
    • Dengjel, J.1    Schoor, O.2    Fischer, R.3    Reich, M.4    Kraus, M.5    Muller, M.6
  • 13
    • 84862888230 scopus 로고    scopus 로고
    • Autophagy: an emerging immunological paradigm
    • Deretic, V. (2012a). Autophagy: an emerging immunological paradigm. J. Immunol. 189, 15-20.
    • (2012) J. Immunol. , vol.189 , pp. 15-20
    • Deretic, V.1
  • 14
    • 84857039937 scopus 로고    scopus 로고
    • Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors
    • Deretic, V. (2012b). Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors. Curr. Opin. Immunol. 24, 21-31.
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 21-31
    • Deretic, V.1
  • 15
    • 83455173649 scopus 로고    scopus 로고
    • Autophagy proteins regulate the secretory component of osteoclastic bone resorption
    • DeSelm, C. J., Miller, B. C., Zou, W., Beatty, W. L., van Meel, E., Takahata, Y., et al. (2011). Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev. Cell 21, 966-974.
    • (2011) Dev. Cell , vol.21 , pp. 966-974
    • DeSelm, C.J.1    Miller, B.C.2    Zou, W.3    Beatty, W.L.4    van Meel, E.5    Takahata, Y.6
  • 16
    • 82455210868 scopus 로고    scopus 로고
    • Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta
    • Dupont, N., Jiang, S., Pilli, M., Ornatowski, W., Bhattacharya, D., and Deretic, V. (2011). Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta. EMBO J. 30, 4701-4711.
    • (2011) EMBO J. , vol.30 , pp. 4701-4711
    • Dupont, N.1    Jiang, S.2    Pilli, M.3    Ornatowski, W.4    Bhattacharya, D.5    Deretic, V.6
  • 17
    • 77149155386 scopus 로고    scopus 로고
    • Unconventional secretion of Acb1 is mediated by autophagosomes
    • Duran, J. M., Anjard, C., Stefan, C., Loomis, W. F., and Malhotra, V. (2010). Unconventional secretion of Acb1 is mediated by autophagosomes. J. Cell Biol. 188, 527-536.
    • (2010) J. Cell Biol. , vol.188 , pp. 527-536
    • Duran, J.M.1    Anjard, C.2    Stefan, C.3    Loomis, W.F.4    Malhotra, V.5
  • 18
    • 52749093177 scopus 로고    scopus 로고
    • Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet
    • Ebato, C., Uchida, T., Arakawa, M., Komatsu, M., Ueno, T., Komiya, K., et al. (2008). Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet. Cell Metab. 8, 325-332.
    • (2008) Cell Metab. , vol.8 , pp. 325-332
    • Ebato, C.1    Uchida, T.2    Arakawa, M.3    Komatsu, M.4    Ueno, T.5    Komiya, K.6
  • 19
    • 67349269904 scopus 로고    scopus 로고
    • Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection
    • English, L., Chemali, M., Duron, J., Rondeau, C., Laplante, A., Gingras, D., et al. (2009). Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat. Immunol. 10, 480-487.
    • (2009) Nat. Immunol. , vol.10 , pp. 480-487
    • English, L.1    Chemali, M.2    Duron, J.3    Rondeau, C.4    Laplante, A.5    Gingras, D.6
  • 20
    • 33746691954 scopus 로고    scopus 로고
    • Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
    • Espert, L., Denizot, M., Grimaldi, M., Robert-Hebmann, V., Gay, B., Varbanov, M., et al. (2006). Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J. Clin. Invest. 116, 2161-2172.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2161-2172
    • Espert, L.1    Denizot, M.2    Grimaldi, M.3    Robert-Hebmann, V.4    Gay, B.5    Varbanov, M.6
  • 21
    • 77951214891 scopus 로고    scopus 로고
    • Role of the innate immune system in the pathogenesis of multiple sclerosis
    • Gandhi, R., Laroni, A., and Weiner, H. L. (2010). Role of the innate immune system in the pathogenesis of multiple sclerosis. J. Neuroimmunol. 221, 7-14.
    • (2010) J. Neuroimmunol. , vol.221 , pp. 7-14
    • Gandhi, R.1    Laroni, A.2    Weiner, H.L.3
  • 22
    • 79953155924 scopus 로고    scopus 로고
    • MHC presentation via autophagy and how viruses escape from it
    • Gannage, M., and Munz, C. (2010). MHC presentation via autophagy and how viruses escape from it. Semin. Immunopathol. 32, 373-381.
    • (2010) Semin. Immunopathol. , vol.32 , pp. 373-381
    • Gannage, M.1    Munz, C.2
  • 23
    • 70350650472 scopus 로고    scopus 로고
    • A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
    • Gateva, V., Sandling, J. K., Hom, G., Taylor, K. E., Chung, S. A., Sun, X., et al. (2009). A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat. Genet. 41, 1228-1233.
    • (2009) Nat. Genet. , vol.41 , pp. 1228-1233
    • Gateva, V.1    Sandling, J.K.2    Hom, G.3    Taylor, K.E.4    Chung, S.A.5    Sun, X.6
  • 24
    • 2342585484 scopus 로고    scopus 로고
    • Autolysosomes accumulate during in vitro CD8+ T-lymphocyte aging and may participate in induced death sensitization of senescent cells
    • Gerland, L. M., Genestier, L., Peyrol, S., Michallet, M. C., Hayette, S., Urbanowicz, I., et al. (2004). Autolysosomes accumulate during in vitro CD8+ T-lymphocyte aging and may participate in induced death sensitization of senescent cells. Exp. Gerontol. 39, 789-800.
    • (2004) Exp. Gerontol. , vol.39 , pp. 789-800
    • Gerland, L.M.1    Genestier, L.2    Peyrol, S.3    Michallet, M.C.4    Hayette, S.5    Urbanowicz, I.6
  • 26
    • 73849134001 scopus 로고    scopus 로고
    • Blocking interleukin-1 in rheumatic diseases
    • Goldbach-Mansky, R. (2009). Blocking interleukin-1 in rheumatic diseases. Ann. N. Y. Acad. Sci. 1182, 111-123.
    • (2009) Ann. N. Y. Acad. Sci. , vol.1182 , pp. 111-123
    • Goldbach-Mansky, R.1
  • 27
    • 77955475968 scopus 로고    scopus 로고
    • NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses
    • Gris, D., Ye, Z., Iocca, H. A., Wen, H., Craven, R. R., Gris, P., et al. (2010). NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. J. Immunol. 185, 974-981.
    • (2010) J. Immunol. , vol.185 , pp. 974-981
    • Gris, D.1    Ye, Z.2    Iocca, H.A.3    Wen, H.4    Craven, R.R.5    Gris, P.6
  • 28
    • 70350629871 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
    • Han, J. W., Zheng, H. F., Cui, Y., Sun, L. D., Ye, D. Q., Hu, Z., et al. (2009). Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat. Genet. 41, 1234-1237.
    • (2009) Nat. Genet. , vol.41 , pp. 1234-1237
    • Han, J.W.1    Zheng, H.F.2    Cui, Y.3    Sun, L.D.4    Ye, D.Q.5    Hu, Z.6
  • 29
    • 38649125210 scopus 로고    scopus 로고
    • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    • Harley, J. B., Alarcon-Riquelme, M. E., Criswell, L. A., Jacob, C. O., Kimberly, R. P., Moser, K. L., et al. (2008). Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat. Genet. 40, 204-210.
    • (2008) Nat. Genet. , vol.40 , pp. 204-210
    • Harley, J.B.1    Alarcon-Riquelme, M.E.2    Criswell, L.A.3    Jacob, C.O.4    Kimberly, R.P.5    Moser, K.L.6
  • 30
    • 79960081347 scopus 로고    scopus 로고
    • Identification of a lysosomal pathway that modulates glucocorticoid signaling and the inflammatory response
    • He, Y., Xu, Y., Zhang, C., Gao, X., Dykema, K. J., Martin, K. R., et al. (2011). Identification of a lysosomal pathway that modulates glucocorticoid signaling and the inflammatory response. Sci. Signal. 4, ra44.
    • (2011) Sci. Signal. , vol.4 , pp. 44
    • He, Y.1    Xu, Y.2    Zhang, C.3    Gao, X.4    Dykema, K.J.5    Martin, K.R.6
  • 31
    • 84870861513 scopus 로고    scopus 로고
    • Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes
    • Henault, J., Martinez, J., Riggs, J. M., Tian, J., Mehta, P., Clarke, L., et al. (2012). Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes. Immunity 37, 986-997.
    • (2012) Immunity , vol.37 , pp. 986-997
    • Henault, J.1    Martinez, J.2    Riggs, J.M.3    Tian, J.4    Mehta, P.5    Clarke, L.6
  • 34
    • 84855516226 scopus 로고    scopus 로고
    • Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells
    • Ireland, J. M., and Unanue, E. R. (2011). Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells. J. Exp. Med. 208, 2625-2632.
    • (2011) J. Exp. Med. , vol.208 , pp. 2625-2632
    • Ireland, J.M.1    Unanue, E.R.2
  • 35
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., et al. (2009). Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 139, 485-498.
    • (2009) Cell , vol.139 , pp. 485-498
    • Ivanov, I.I.1    Atarashi, K.2    Manel, N.3    Brodie, E.L.4    Shima, T.5    Karaoz, U.6
  • 36
    • 62049084947 scopus 로고    scopus 로고
    • Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
    • Jagannath, C., Lindsey, D. R., Dhandayuthapani, S., Xu, Y., Hunter, R. L. Jr., and Eissa, N. T. (2009). Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat. Med. 15, 267-276.
    • (2009) Nat. Med. , vol.15 , pp. 267-276
    • Jagannath, C.1    Lindsey, D.R.2    Dhandayuthapani, S.3    Xu, Y.4    Hunter Jr., R.L.5    Eissa, N.T.6
  • 37
    • 79955540204 scopus 로고    scopus 로고
    • Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy
    • Jia, W., and He, Y. W. (2011). Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy. J. Immunol. 186, 5313-5322.
    • (2011) J. Immunol. , vol.186 , pp. 5313-5322
    • Jia, W.1    He, Y.W.2
  • 38
    • 79251534395 scopus 로고    scopus 로고
    • Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes
    • Jia, W., Pua, H. H., Li, Q. J., and He, Y. W. (2011). Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes. J. Immunol. 186, 1564-1574.
    • (2011) J. Immunol. , vol.186 , pp. 1564-1574
    • Jia, W.1    Pua, H.H.2    Li, Q.J.3    He, Y.W.4
  • 40
    • 52749094770 scopus 로고    scopus 로고
    • Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia
    • Jung, H. S., Chung, K. W., Won Kim, J., Kim, J., Komatsu, M., Tanaka, K., et al. (2008). Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia. Cell Metab. 8, 318-324.
    • (2008) Cell Metab. , vol.8 , pp. 318-324
    • Jung, H.S.1    Chung, K.W.2    Won Kim, J.3    Kim, J.4    Komatsu, M.5    Tanaka, K.6
  • 41
    • 73349138896 scopus 로고    scopus 로고
    • Autophagic compartments gain access to the MHC class II compartments in thymic epithelium
    • Kasai, M., Tanida, I., Ueno, T., Kominami, E., Seki, S., Ikeda, T., et al. (2009). Autophagic compartments gain access to the MHC class II compartments in thymic epithelium. J. Immunol. 183, 7278-7285.
    • (2009) J. Immunol. , vol.183 , pp. 7278-7285
    • Kasai, M.1    Tanida, I.2    Ueno, T.3    Kominami, E.4    Seki, S.5    Ikeda, T.6
  • 42
    • 70349843323 scopus 로고    scopus 로고
    • Nrf2:INrf2 (Keap1) signaling in oxidative stress
    • Kaspar, J. W., Niture, S. K., and Jaiswal, A. K. (2009). Nrf2:INrf2 (Keap1) signaling in oxidative stress. Free Radic. Biol. Med. 47, 1304-1309.
    • (2009) Free Radic. Biol. Med. , vol.47 , pp. 1304-1309
    • Kaspar, J.W.1    Niture, S.K.2    Jaiswal, A.K.3
  • 44
    • 36849089101 scopus 로고    scopus 로고
    • Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
    • Komatsu, M., Waguri, S., Koike, M., Sou, Y. S., Ueno, T., Hara, T., et al. (2007). Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 131, 1149-1163.
    • (2007) Cell , vol.131 , pp. 1149-1163
    • Komatsu, M.1    Waguri, S.2    Koike, M.3    Sou, Y.S.4    Ueno, T.5    Hara, T.6
  • 46
    • 63849182862 scopus 로고    scopus 로고
    • Natural Tregs and autoimmunity
    • La Cava, A. (2009). Natural Tregs and autoimmunity. Front. Biosci. 14, 333-343.
    • (2009) Front. Biosci. , vol.14 , pp. 333-343
    • La Cava, A.1
  • 47
    • 77649194674 scopus 로고    scopus 로고
    • Crohn's disease-associated adherent-invasive E.coli are selectively favoured by impaired autophagy to replicate intracellularly.
    • Lapaquette, P., Glasser, A. L., Huett, A., Xavier, R. J., and Darfeuille-Michaud, A. (2010). Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly. Cell Microbiol. 12, 99-113.
    • (2010) Cell Microbiol. , vol.12 , pp. 99-113
    • Lapaquette, P.1    Glasser, A.L.2    Huett, A.3    Xavier, R.J.4    Darfeuille-Michaud, A.5
  • 48
    • 33947134377 scopus 로고    scopus 로고
    • Autophagy-dependent viral recognition by plasmacytoid dendritic cells
    • Lee, H. K., Lund, J. M., Ramanathan, B., Mizushima, N., and Iwasaki, A. (2007). Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 315, 1398-1401.
    • (2007) Science , vol.315 , pp. 1398-1401
    • Lee, H.K.1    Lund, J.M.2    Ramanathan, B.3    Mizushima, N.4    Iwasaki, A.5
  • 49
    • 76949091325 scopus 로고    scopus 로고
    • In vivo requirement for Atg5 in antigen presentation by dendritic cells
    • Lee, H. K., Mattei, L. M., Steinberg, B. E., Alberts, P., Lee, Y. H., Chervonsky, A., et al. (2010). In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity 32, 227-239.
    • (2010) Immunity , vol.32 , pp. 227-239
    • Lee, H.K.1    Mattei, L.M.2    Steinberg, B.E.3    Alberts, P.4    Lee, Y.H.5    Chervonsky, A.6
  • 50
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine, B., Mizushima, N., and Virgin, H. W. (2011). Autophagy in immunity and inflammation. Nature 469, 323-335.
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 51
    • 84861235405 scopus 로고    scopus 로고
    • Emerging therapies for systemic lupus erythematosus - focus on targeting interferon-alpha
    • Lichtman, E. I., Helfgott, S. M., and Kriegel, M. A. (2012). Emerging therapies for systemic lupus erythematosus - focus on targeting interferon-alpha. Clin. Immunol. 143, 210-221.
    • (2012) Clin. Immunol. , vol.143 , pp. 210-221
    • Lichtman, E.I.1    Helfgott, S.M.2    Kriegel, M.A.3
  • 53
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: crosstalk between autophagy and apoptosis
    • Maiuri, M. C., Zalckvar, E., Kimchi, A., and Kroemer, G. (2007). Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat. Rev. Mol. Cell Biol. 8, 741-752.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 55
    • 77149152566 scopus 로고    scopus 로고
    • Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation
    • Manjithaya, R., Anjard, C., Loomis, W. F., and Subramani, S. (2010). Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation. J. Cell Biol. 188, 537-546.
    • (2010) J. Cell Biol. , vol.188 , pp. 537-546
    • Manjithaya, R.1    Anjard, C.2    Loomis, W.F.3    Subramani, S.4
  • 56
    • 63049109258 scopus 로고    scopus 로고
    • Phagocytosis of bacteria is enhanced in macrophages undergoing nutrient deprivation
    • Martinet, W., Schrijvers, D. M., Timmermans, J. P., Herman, A. G., and De Meyer, G. R. (2009). Phagocytosis of bacteria is enhanced in macrophages undergoing nutrient deprivation. FEBS J. 276, 2227-2240.
    • (2009) FEBS J. , vol.276 , pp. 2227-2240
    • Martinet, W.1    Schrijvers, D.M.2    Timmermans, J.P.3    Herman, A.G.4    De Meyer, G.R.5
  • 57
    • 80054825045 scopus 로고    scopus 로고
    • Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells
    • Martinez, J., Almendinger, J., Oberst, A., Ness, R., Dillon, C. P., Fitzgerald, P., et al. (2011). Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells. Proc. Natl. Acad. Sci. U.S.A. 108, 17396-17401.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 17396-17401
    • Martinez, J.1    Almendinger, J.2    Oberst, A.3    Ness, R.4    Dillon, C.P.5    Fitzgerald, P.6
  • 58
    • 68049119930 scopus 로고    scopus 로고
    • An integrated classification of pediatric inflammatory diseases, based on the concepts of autoinflammation and the immunological disease continuum
    • McGonagle, D., Aziz, A., Dickie, L. J., and McDermott, M. F. (2009). An integrated classification of pediatric inflammatory diseases, based on the concepts of autoinflammation and the immunological disease continuum. Pediatr. Res. 65, 38R-45R.
    • (2009) Pediatr. Res. , vol.65
    • McGonagle, D.1    Aziz, A.2    Dickie, L.J.3    McDermott, M.F.4
  • 59
    • 41449106674 scopus 로고    scopus 로고
    • The autophagy gene ATG5 plays an essential role in B lymphocyte development
    • Miller, B. C., Zhao, Z., Stephenson, L. M., Cadwell, K., Pua, H. H., Lee, H. K., et al. (2008). The autophagy gene ATG5 plays an essential role in B lymphocyte development. Autophagy 4, 309-314.
    • (2008) Autophagy , vol.4 , pp. 309-314
    • Miller, B.C.1    Zhao, Z.2    Stephenson, L.M.3    Cadwell, K.4    Pua, H.H.5    Lee, H.K.6
  • 60
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: renovation of cells and tissues
    • Mizushima, N., and Komatsu, M. (2011). Autophagy: renovation of cells and tissues. Cell 147, 728-741.
    • (2011) Cell , vol.147 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 61
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima, N., Yamamoto, A., Matsui, M., Yoshimori, T., and Ohsumi, Y. (2004). In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol. Biol. Cell 15, 1101-1111.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 62
    • 65249187333 scopus 로고    scopus 로고
    • Enhancing immunity through autophagy
    • Munz, C. (2009). Enhancing immunity through autophagy. Annu. Rev. Immunol. 27, 423-449.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 423-449
    • Munz, C.1
  • 63
    • 79951642032 scopus 로고    scopus 로고
    • Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
    • Nakahira, K., Haspel, J. A., Rathinam, V. A., Lee, S. J., Dolinay, T., Lam, H. C., et al. (2011). Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat. Immunol. 12, 222-230.
    • (2011) Nat. Immunol. , vol.12 , pp. 222-230
    • Nakahira, K.1    Haspel, J.A.2    Rathinam, V.A.3    Lee, S.J.4    Dolinay, T.5    Lam, H.C.6
  • 64
    • 52149099867 scopus 로고    scopus 로고
    • Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
    • Nedjic, J., Aichinger, M., Emmerich, J., Mizushima, N., and Klein, L. (2008). Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature 455, 396-400.
    • (2008) Nature , vol.455 , pp. 396-400
    • Nedjic, J.1    Aichinger, M.2    Emmerich, J.3    Mizushima, N.4    Klein, L.5
  • 65
    • 77249096486 scopus 로고    scopus 로고
    • Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis
    • Ochoa-Reparaz, J., Mielcarz, D. W., Ditrio, L. E., Burroughs, A. R., Foureau, D. M., Haque-Begum, S., et al. (2009). Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis. J. Immunol. 183, 6041-6050.
    • (2009) J. Immunol. , vol.183 , pp. 6041-6050
    • Ochoa-Reparaz, J.1    Mielcarz, D.W.2    Ditrio, L.E.3    Burroughs, A.R.4    Foureau, D.M.5    Haque-Begum, S.6
  • 66
    • 33748069813 scopus 로고    scopus 로고
    • Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
    • Ozcan, U., Yilmaz, E., Ozcan, L., Furuhashi, M., Vaillancourt, E., Smith, R. O., et al. (2006). Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313, 1137-1140.
    • (2006) Science , vol.313 , pp. 1137-1140
    • Ozcan, U.1    Yilmaz, E.2    Ozcan, L.3    Furuhashi, M.4    Vaillancourt, E.5    Smith, R.O.6
  • 67
    • 34347338690 scopus 로고    scopus 로고
    • Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
    • Parkes, M., Barrett, J. C., Prescott, N. J., Tremelling, M., Anderson, C. A., Fisher, S. A., et al. (2007). Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat. Genet. 39, 830-832.
    • (2007) Nat. Genet. , vol.39 , pp. 830-832
    • Parkes, M.1    Barrett, J.C.2    Prescott, N.J.3    Tremelling, M.4    Anderson, C.A.5    Fisher, S.A.6
  • 68
    • 84860899836 scopus 로고    scopus 로고
    • Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus
    • Pierdominici, M., Vomero, M., Barbati, C., Colasanti, T., Maselli, A., Vacirca, D., et al. (2012). Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus. FASEB J. 26, 1400-1412.
    • (2012) FASEB J. , vol.26 , pp. 1400-1412
    • Pierdominici, M.1    Vomero, M.2    Barbati, C.3    Colasanti, T.4    Maselli, A.5    Vacirca, D.6
  • 69
    • 33846461678 scopus 로고    scopus 로고
    • A critical role for the autophagy gene Atg5 in T cell survival and proliferation
    • Pua, H. H., Dzhagalov, I., Chuck, M., Mizushima, N., and He, Y. W. (2007). A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J. Exp. Med. 204, 25-31.
    • (2007) J. Exp. Med. , vol.204 , pp. 25-31
    • Pua, H.H.1    Dzhagalov, I.2    Chuck, M.3    Mizushima, N.4    He, Y.W.5
  • 70
    • 64249123646 scopus 로고    scopus 로고
    • Autophagy is essential for mitochondrial clearance in mature T lymphocytes
    • Pua, H. H., Guo, J., Komatsu, M., and He, Y. W. (2009). Autophagy is essential for mitochondrial clearance in mature T lymphocytes. J. Immunol. 182, 4046-4055.
    • (2009) J. Immunol. , vol.182 , pp. 4046-4055
    • Pua, H.H.1    Guo, J.2    Komatsu, M.3    He, Y.W.4
  • 71
    • 33847404337 scopus 로고    scopus 로고
    • Autophagy gene-dependent clearance of apoptotic cells during embryonic development
    • Qu, X., Zou, Z., Sun, Q., Luby-Phelps, K., Cheng, P., Hogan, R. N., et al. (2007). Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell 128, 931-946.
    • (2007) Cell , vol.128 , pp. 931-946
    • Qu, X.1    Zou, Z.2    Sun, Q.3    Luby-Phelps, K.4    Cheng, P.5    Hogan, R.N.6
  • 72
    • 84863258890 scopus 로고    scopus 로고
    • Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic beta-cells
    • Quan, W., Lim, Y. M., and Lee, M. S. (2012). Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic beta-cells. Exp. Mol. Med. 44, 81-88.
    • (2012) Exp. Mol. Med. , vol.44 , pp. 81-88
    • Quan, W.1    Lim, Y.M.2    Lee, M.S.3
  • 73
    • 84866767594 scopus 로고    scopus 로고
    • Autophagy in the regulation of pathogen replication and adaptive immunity
    • Randow, F., and Munz, C. (2012). Autophagy in the regulation of pathogen replication and adaptive immunity. Trends Immunol. 33, 475-487.
    • (2012) Trends Immunol. , vol.33 , pp. 475-487
    • Randow, F.1    Munz, C.2
  • 74
    • 70649086092 scopus 로고    scopus 로고
    • Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
    • Raychaudhuri, S., Thomson, B. P., Remmers, E. F., Eyre, S., Hinks, A., Guiducci, C., et al. (2009). Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat. Genet. 41, 1313-1318.
    • (2009) Nat. Genet. , vol.41 , pp. 1313-1318
    • Raychaudhuri, S.1    Thomson, B.P.2    Remmers, E.F.3    Eyre, S.4    Hinks, A.5    Guiducci, C.6
  • 75
    • 61449261856 scopus 로고    scopus 로고
    • A defect in marco expression contributes to systemic lupus erythematosus development via failure to clear apoptotic cells
    • Rogers, N. J., Lees, M. J., Gabriel, L., Maniati, E., Rose, S. J., Potter, P. K., et al. (2009). A defect in marco expression contributes to systemic lupus erythematosus development via failure to clear apoptotic cells. J. Immunol. 182, 1982-1990.
    • (2009) J. Immunol. , vol.182 , pp. 1982-1990
    • Rogers, N.J.1    Lees, M.J.2    Gabriel, L.3    Maniati, E.4    Rose, S.J.5    Potter, P.K.6
  • 76
    • 37549043217 scopus 로고    scopus 로고
    • Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
    • Sanjuan, M. A., Dillon, C. P., Tait, S. W., Moshiach, S., Dorsey, F., Connell, S., et al. (2007). Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature 450, 1253-1257.
    • (2007) Nature , vol.450 , pp. 1253-1257
    • Sanjuan, M.A.1    Dillon, C.P.2    Tait, S.W.3    Moshiach, S.4    Dorsey, F.5    Connell, S.6
  • 77
    • 34447629523 scopus 로고    scopus 로고
    • Innate and adaptive immunity through autophagy
    • Schmid, D., and Munz, C. (2007). Innate and adaptive immunity through autophagy. Immunity 27, 11-21.
    • (2007) Immunity , vol.27 , pp. 11-21
    • Schmid, D.1    Munz, C.2
  • 78
    • 33846224369 scopus 로고    scopus 로고
    • Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes
    • Schmid, D., Pypaert, M., and Munz, C. (2007). Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes. Immunity 26, 79-92.
    • (2007) Immunity , vol.26 , pp. 79-92
    • Schmid, D.1    Pypaert, M.2    Munz, C.3
  • 79
    • 77954478334 scopus 로고    scopus 로고
    • Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis
    • Shaw, P. J., Lukens, J. R., Burns, S., Chi, H., McGargill, M. A., and Kanneganti, T. D. (2010). Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. J. Immunol. 184, 4610-4614.
    • (2010) J. Immunol. , vol.184 , pp. 4610-4614
    • Shaw, P.J.1    Lukens, J.R.2    Burns, S.3    Chi, H.4    McGargill, M.A.5    Kanneganti, T.D.6
  • 81
    • 77956180361 scopus 로고    scopus 로고
    • Autophagy and innate immunity: triggering, targeting and tuning
    • Sumpter, R. Jr., and Levine, B. (2010). Autophagy and innate immunity: triggering, targeting and tuning. Semin. Cell Dev. Biol. 21, 699-711.
    • (2010) Semin. Cell Dev. Biol. , vol.21 , pp. 699-711
    • Sumpter Jr., R.1    Levine, B.2
  • 82
    • 38049094279 scopus 로고    scopus 로고
    • The non-canonical role of Atg family members as suppressors of innate antiviral immune signaling
    • Takeshita, F., Kobiyama, K., Miyawaki, A., Jounai, N., and Okuda, K. (2008). The non-canonical role of Atg family members as suppressors of innate antiviral immune signaling. Autophagy 4, 67-69.
    • (2008) Autophagy , vol.4 , pp. 67-69
    • Takeshita, F.1    Kobiyama, K.2    Miyawaki, A.3    Jounai, N.4    Okuda, K.5
  • 83
    • 62449110463 scopus 로고    scopus 로고
    • Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
    • Tal, M. C., Sasai, M., Lee, H. K., Yordy, B., Shadel, G. S., and Iwasaki, A. (2009). Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc. Natl. Acad. Sci. U.S.A. 106, 2770-2775.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 2770-2775
    • Tal, M.C.1    Sasai, M.2    Lee, H.K.3    Yordy, B.4    Shadel, G.S.5    Iwasaki, A.6
  • 84
    • 84865299726 scopus 로고    scopus 로고
    • PAMPs and DAMPs: signal 0s that spur autophagy and immunity
    • Tang, D., Kang, R., Coyne, C. B., Zeh, H. J., and Lotze, M. T. (2012). PAMPs and DAMPs: signal 0s that spur autophagy and immunity. Immunol. Rev. 249, 158-175.
    • (2012) Immunol. Rev. , vol.249 , pp. 158-175
    • Tang, D.1    Kang, R.2    Coyne, C.B.3    Zeh, H.J.4    Lotze, M.T.5
  • 85
    • 67549117101 scopus 로고    scopus 로고
    • Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells
    • Uhl, M., Kepp, O., Jusforgues-Saklani, H., Vicencio, J. M., Kroemer, G., and Albert, M. L. (2009). Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells. Cell Death Differ. 16, 991-1005.
    • (2009) Cell Death Differ. , vol.16 , pp. 991-1005
    • Uhl, M.1    Kepp, O.2    Jusforgues-Saklani, H.3    Vicencio, J.M.4    Kroemer, G.5    Albert, M.L.6
  • 87
    • 50949108510 scopus 로고    scopus 로고
    • Induction of autophagy by B cell antigen receptor stimulation and its inhibition by costimulation
    • Watanabe, K., Ichinose, S., Hayashizaki, K., and Tsubata, T. (2008). Induction of autophagy by B cell antigen receptor stimulation and its inhibition by costimulation. Biochem. Biophys. Res. Commun. 374, 274-281.
    • (2008) Biochem. Biophys. Res. Commun. , vol.374 , pp. 274-281
    • Watanabe, K.1    Ichinose, S.2    Hayashizaki, K.3    Tsubata, T.4
  • 88
    • 67649844269 scopus 로고    scopus 로고
    • Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control
    • Wirnsberger, G., Mair, F., and Klein, L. (2009). Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control. Proc. Natl. Acad. Sci. U.S.A. 106, 10278-10283.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 10278-10283
    • Wirnsberger, G.1    Mair, F.2    Klein, L.3
  • 89
    • 84862509819 scopus 로고    scopus 로고
    • Metabolic disturbances associated with systemic lupus erythematosus
    • doi:10.1371/journal.pone.0037210
    • Wu, T., Xie, C., Han, J., Ye, Y., Weiel, J., Li, Q., et al. (2012). Metabolic disturbances associated with systemic lupus erythematosus. PLoS ONE 7:e37210. doi:10.1371/journal.pone.0037210
    • (2012) PLoS ONE , vol.7
    • Wu, T.1    Xie, C.2    Han, J.3    Ye, Y.4    Weiel, J.5    Li, Q.6
  • 90
    • 84860504609 scopus 로고    scopus 로고
    • Low dose rapamycin exacerbates autoimmune experimental uveitis
    • doi:10.1371/journal.pone.0036589
    • Zhang, Z, Wu, X., Duan, J., Hinrichs, D., Wegmann, K., Zhang, G. L., et al. (2012). Low dose rapamycin exacerbates autoimmune experimental uveitis. PLoS ONE 7:e36589. doi:10.1371/journal.pone.0036589
    • (2012) PLoS ONE , vol.7
    • Zhang, Z.1    Wu, X.2    Duan, J.3    Hinrichs, D.4    Wegmann, K.5    Zhang, G.L.6
  • 91
    • 79957629559 scopus 로고    scopus 로고
    • Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population
    • Zhou, X. J., Lu, X. L., Lv, J. C., Yang, H. Z., Qin, L. X., Zhao, M. H., et al. (2011a). Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population. Ann. Rheum. Dis. 70, 1330-1337.
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 1330-1337
    • Zhou, X.J.1    Lu, X.L.2    Lv, J.C.3    Yang, H.Z.4    Qin, L.X.5    Zhao, M.H.6
  • 92
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou, R., Yazdi, A. S., Menu, P., and Tschopp, J. (2011b). A role for mitochondria in NLRP3 inflammasome activation. Nature 469, 221-225.
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4


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