메뉴 건너뛰기




Volumn 59, Issue 1-3, 2015, Pages 73-78

Programmed cell death in the skin

Author keywords

Apoptosis; Cornification; Skin disease

Indexed keywords

CASPASE 3; CYTOCHROME C; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEINASE;

EID: 84940666994     PISSN: 02146282     EISSN: 16963547     Source Type: Journal    
DOI: 10.1387/ijdb.150050ac     Document Type: Article
Times cited : (25)

References (68)
  • 1
    • 70349745535 scopus 로고    scopus 로고
    • Degradation by stratum corneum proteases prevents endogenous RNase inhibitor from blocking antimicrobial activities of RNase 5 and RNase 7
    • ABTIN, A., ECKHART, L., MILDNER, M., GHANNADAN, M., HARDER, J., SCHRODER, J.M., TSCHACHLER, E., (2009). Degradation by stratum corneum proteases prevents endogenous RNase inhibitor from blocking antimicrobial activities of RNase 5 and RNase 7. J. Invest. Dermatol. 129: 2193-2201.
    • (2009) J. Invest. Dermatol , vol.129 , pp. 2193-2201
    • Abtin, A.1    Eckhart, L.2    Mildner, M.3    Ghannadan, M.4    Harder, J.5    Schroder, J.M.6    Tschachler, E.7
  • 3
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-kappaB activation pathways and their role in innate and adaptive immunity
    • BONIZZI G, K.M., (2004). The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol.: 280-288.
    • (2004) Trends Immunol , pp. 280-288
    • Bonizzi G, K.M.1
  • 4
    • 0035514046 scopus 로고    scopus 로고
    • Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim
    • BOUILLET, P., CORY, S., ZHANG, L.C., STRASSER, A., ADAMS, J.M., (2001). Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim. Dev Cell 1: 645-653.
    • (2001) Dev Cell , vol.1 , pp. 645-653
    • Bouillet, P.1    Cory, S.2    Zhang, L.C.3    Strasser, A.4    Adams, J.M.5
  • 6
    • 0028070989 scopus 로고
    • P53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
    • CAELLES, C., HELMBERG, A., KARIN, M., (1994). p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370: 220-223.
    • (1994) Nature , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 7
    • 17144371855 scopus 로고    scopus 로고
    • The cornified envelope: A model of cell death in the skin
    • CANDI, E., SCHMIDT, R., MELINO, G., (2005). The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol. 6: 328-340.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 328-340
    • Candi, E.1    Schmidt, R.2    Melino, G.3
  • 8
    • 33745203039 scopus 로고    scopus 로고
    • Epithelial stem cells: A folliculocentric view
    • COTSARELIS, G., (2006). Epithelial stem cells: a folliculocentric view. J. Invest. Dermatol. 126: 1459-1468.
    • (2006) J. Invest. Dermatol , vol.126 , pp. 1459-1468
    • Cotsarelis, G.1
  • 9
    • 73049133188 scopus 로고
    • Histochemical responses of human skin following ultraviolet irradiation
    • DANIELS, F., Jr., BROPHY, D., LOBITZ, W.C., Jr., (1961). Histochemical responses of human skin following ultraviolet irradiation. J. Invest. Dermatol. 37: 351-357.
    • (1961) J. Invest. Dermatol , vol.37 , pp. 351-357
    • Daniels, F.1    Brophy, D.2    Lobitz, W.C.3
  • 10
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • DATTA, S.R., DUDEK, H., TAO, X., MASTERS, S., FU, H., GOTOH, Y., GREENBERG, M.E., 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91: 231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 12
    • 18144421236 scopus 로고    scopus 로고
    • Stress-induced p53 runs a transcription-independent death program
    • ERSTER, S., MOLL, U.M., (2005). Stress-induced p53 runs a transcription-independent death program. Biochem Biophys Res Commun 331: 843-850.
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 843-850
    • Erster, S.1    Moll, U.M.2
  • 13
    • 37249058334 scopus 로고    scopus 로고
    • The importance of lipids in cutaneous function
    • FEINGOLD, K.R., (2007). The importance of lipids in cutaneous function. J Lipid Res 48: 2529-2530.
    • (2007) J Lipid Res , vol.48 , pp. 2529-2530
    • Feingold, K.R.1
  • 16
    • 0034614379 scopus 로고    scopus 로고
    • Stem cells: A new lease on life
    • FUCHS, E., SEGRE, J.A., (2000). Stem cells: a new lease on life. Cell 100: 143-155.
    • (2000) Cell , vol.100 , pp. 143-155
    • Fuchs, E.1    Segre, J.A.2
  • 17
    • 0347481387 scopus 로고    scopus 로고
    • Mitochondrial cytochrome c release mediates ceramide-induced activator protein 2 activation and gene expression in keratinocytes
    • Grether-Beck, S., FELSNER, I., BRENDEN, H., KRUTMANN, J., (2003). Mitochondrial cytochrome c release mediates ceramide-induced activator protein 2 activation and gene expression in keratinocytes. J Biol Chem 278: 47498-47507.
    • (2003) J Biol Chem , vol.278 , pp. 47498-47507
    • Grether-Beck, S.1    Felsner, I.2    Brenden, H.3    Krutmann, J.4
  • 18
    • 2942716835 scopus 로고    scopus 로고
    • The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms
    • GUGASYAN, R., VOSS, A., VARIGOS, G., THOMAS, T., GRUMONT, R.J., KAUR, P., GRIGORIADIS, G., GERONDAKIS, S., (2004). The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms. Mol Cell Biol 24: 5733-5745.
    • (2004) Mol Cell Biol , vol.24 , pp. 5733-5745
    • Gugasyan, R.1    Voss, A.2    Varigos, G.3    Thomas, T.4    Grumont, R.J.5    Kaur, P.6    Grigoriadis, G.7    Gerondakis, S.8
  • 19
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKK-related kinases
    • re13
    • HACKER, H., KARIN, M., (2006). Regulation and function of IKK and IKK-related kinases. Sci STKE 2006, re13.
    • (2006) Sci STKE
    • Hacker, H.1    Karin, M.2
  • 23
    • 0032925237 scopus 로고    scopus 로고
    • Removal of stem cell factor or addition of monoclonal anti-c-KIT antibody induces apoptosis in murine melanocyte precursors
    • ITO, M., KAWA, Y., ONO, H., OKURA, M., BABA, T., KUBOTA, Y., NISHIKAWA, S.I., MIZOGUCHI, M., (1999). Removal of stem cell factor or addition of monoclonal anti-c-KIT antibody induces apoptosis in murine melanocyte precursors. J. Invest. Dermatol.112, 796-801.
    • (1999) J. Invest. Dermatol , vol.112 , pp. 796-801
    • Ito, M.1    Kawa, Y.2    Ono, H.3    Okura, M.4    Baba, T.5    Kubota, Y.6    Nishikawa, S.I.7    Mizoguchi, M.8
  • 24
    • 21644487114 scopus 로고    scopus 로고
    • P21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association
    • JIN, S., ZHUO, Y., GUO, W., FIELD, J., (2005). p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association. J Biol Chem 280: 24698-24705.
    • (2005) J Biol Chem , vol.280 , pp. 24698-24705
    • Jin, S.1    Zhuo, Y.2    Guo, W.3    Field, J.4
  • 25
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
    • KARIN, M., Ben-Neriah, Y., (2000). Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol 18: 621-663.
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 28
    • 0029990550 scopus 로고    scopus 로고
    • Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family
    • KRAJEWSKI, S., KRAJEWSKA, M., REED, J.C., (1996). Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family. Cancer Res 56: 2849-2855.
    • (1996) Cancer Res , vol.56 , pp. 2849-2855
    • Krajewski, S.1    Krajewska, M.2    Reed, J.C.3
  • 30
    • 0036157925 scopus 로고    scopus 로고
    • Development of ichthyosiform skin compensates for defective permeability barrier function in mice lacking transglutaminase 1
    • KURAMOTO, N., TAKIZAWA, T., TAKIZAWA, T., MATSUKI, M., MORIOKA, H., ROBINSON, J.M., YAMANISHI, K., (2002). Development of ichthyosiform skin compensates for defective permeability barrier function in mice lacking transglutaminase 1. J Clin Invest 109: 243-250.
    • (2002) J Clin Invest , vol.109 , pp. 243-250
    • Kuramoto, N.1    Takizawa, T.2    Takizawa, T.3    Matsuki, M.4    Morioka, H.5    Robinson, J.M.6    Yamanishi, K.7
  • 31
    • 0027109075 scopus 로고
    • Cancer. P53, guardian of the genome
    • LANE, D.P., (1992). Cancer. p53, guardian of the genome. Nature 358: 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 32
    • 0033621638 scopus 로고    scopus 로고
    • Beta1 inte grins regulate keratinocyte adhesion and differentiation by distinct mechanisms
    • LEVY, L., BROAD, S., DIEKMANN, D., EVANS, R.D., WATT, F.M., (2000). beta1 inte grins regulate keratinocyte adhesion and differentiation by distinct mechanisms. Mol Biol Cell 11: 453-466.
    • (2000) Mol Biol Cell , vol.11 , pp. 453-466
    • Levy, L.1    Broad, S.2    Diekmann, D.3    Evans, R.D.4    Watt, F.M.5
  • 34
    • 0038702528 scopus 로고    scopus 로고
    • Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall’s bodies
    • LIPPENS S, V.C., VAN DAMME E, TSCHACHLER E, VANDENABEELE P, DECLERCQ W, (2003). Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall’s bodies. Cell Death Differ, 257-259.
    • (2003) Cell Death Differ , pp. 257-259
    • Lippens S, V.C.1    Van Damme, E.2    Tschachler, E.3    Vandenabeele, P.4    Declercq, W.5
  • 35
    • 0027286802 scopus 로고
    • Bcl-2 expression in adult and embryonic non-haematopoietic tissues
    • LU, Q.L., POULSOM, R., WONG, L., HANBY, A.M., (1993). Bcl-2 expression in adult and embryonic non-haematopoietic tissues. J Pathol 169: 431-437.
    • (1993) J Pathol , vol.169 , pp. 431-437
    • Lu, Q.L.1    Poulsom, R.2    Wong, L.3    Hanby, A.M.4
  • 36
    • 65449183355 scopus 로고    scopus 로고
    • The anatomy and development of the claws of Xenopus laevis (Lissamphibia: Anura) reveal alternate pathways of structural evolution in the integument of tetrapods
    • MADDIN, H.C., ECKHART, L., JAEGER, K., RUSSELL, A.P., GHANNADAN, M., (2009). The anatomy and development of the claws of Xenopus laevis (Lissamphibia: Anura) reveal alternate pathways of structural evolution in the integument of tetrapods. J Anat 214: 607-619.
    • (2009) J Anat , vol.214 , pp. 607-619
    • Maddin, H.C.1    Eckhart, L.2    Jaeger, K.3    Russell, A.P.4    Ghannadan, M.5
  • 37
    • 0033634663 scopus 로고    scopus 로고
    • Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
    • MAKRIS, C., GODFREY, V.L., Krahn-Senftleben, G., TAKAHASHI, T., ROBERTS, J.L., SCHWARZ, T., FENG, L., JOHNSON, R.S., KARIN, M., (2000). Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol Cell 5: 969-979.
    • (2000) Mol Cell , vol.5 , pp. 969-979
    • Makris, C.1    Godfrey, V.L.2    Krahn-Senftleben, G.3    Takahashi, T.4    Roberts, J.L.5    Schwarz, T.6    Feng, L.7    Johnson, R.S.8    Karin, M.9
  • 40
    • 0026215251 scopus 로고
    • Wavelength dependent formation of thymine dimers and (6-4) photoproducts in DNA by monochromatic ultraviolet light ranging from 150 to 365 nm
    • MATSUNAGA, T., HIEDA, K., NIKAIDO, O., (1991). Wavelength dependent formation of thymine dimers and (6-4) photoproducts in DNA by monochromatic ultraviolet light ranging from 150 to 365 nm. Photochem Photobiol 54: 403-410.
    • (1991) Photochem Photobiol , vol.54 , pp. 403-410
    • Matsunaga, T.1    Hieda, K.2    Nikaido, O.3
  • 41
    • 0037119428 scopus 로고    scopus 로고
    • Akt is a downstream target of NF-kappa B
    • MENG F, L.L., CHIN PC, DMELLO SR, (2002). Akt is a downstream target of NF-kappa B. J Biol Chem 277: 29674-29680.
    • (2002) J Biol Chem , vol.277 , pp. 29674-29680
    • Meng F, L.L.1    Chin, P.C.2    Dmello, S.R.3
  • 42
    • 66949178382 scopus 로고    scopus 로고
    • A guide to hair follicle analysis by transmission electron microscopy: Technique and practice
    • MORIOKA, K., (2009). A guide to hair follicle analysis by transmission electron microscopy: technique and practice. Exp Dermatol 18: 577-582.
    • (2009) Exp Dermatol , vol.18 , pp. 577-582
    • Morioka, K.1
  • 43
    • 0033847313 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 protects from ultraviolet B-induced apoptosis but promotes hair follicle regression and chemotherapy-induced alopecia
    • Muller-Rover, S., ROSSITER, H., PAUS, R., HANDJISKI, B., PETERS, E.M., MURPHY, J.E., MECKLENBURG, L., KUPPER, T.S., (2000). Overexpression of Bcl-2 protects from ultraviolet B-induced apoptosis but promotes hair follicle regression and chemotherapy-induced alopecia. Am J Pathol 156: 1395-1405.
    • (2000) Am J Pathol , vol.156 , pp. 1395-1405
    • Muller-Rover, S.1    Rossiter, H.2    Paus, R.3    Handjiski, B.4    Peters, E.M.5    Murphy, J.E.6    Mecklenburg, L.7    Kupper, T.S.8
  • 44
    • 33846997899 scopus 로고    scopus 로고
    • Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa
    • NAIK, E., MICHALAK, E.M., VILLUNGER, A., ADAMS, J.M., STRASSER, A., (2007). Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa. J Cell Biol 176: 415-424.
    • (2007) J Cell Biol , vol.176 , pp. 415-424
    • Naik, E.1    Michalak, E.M.2    Villunger, A.3    Adams, J.M.4    Strasser, A.5
  • 46
    • 0033517189 scopus 로고    scopus 로고
    • NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
    • OZES, O.N., MAYO, L.D., GUSTIN, J.A., PFEFFER, S.R., PFEFFER, L.M., DONNER, D.B., (1999). NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 401: 82-85.
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6
  • 47
    • 84873731727 scopus 로고    scopus 로고
    • The expanding significance of keratin intermediate filaments in normal and diseased epithelia
    • PAN, X., HOBBS, R.P., COULOMBE, P.A., (2013). The expanding significance of keratin intermediate filaments in normal and diseased epithelia. Curr Opin Cell Biol 25: 47-56.
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 47-56
    • Pan, X.1    Hobbs, R.P.2    Coulombe, P.A.3
  • 48
    • 27144448738 scopus 로고    scopus 로고
    • A p38-dependent pathway regulates DeltaNp63 DNA binding to p53-dependent promoters in UV-induced apoptosis of keratinocytes
    • PAPOUTSAKI, M., MORETTI, F., LANZA, M., MARINARI, B., SARTORELLI, V., GUERRINI, L., CHIMENTI, S., LEVRERO, M., COSTANZO, A., (2005). A p38-dependent pathway regulates DeltaNp63 DNA binding to p53-dependent promoters in UV-induced apoptosis of keratinocytes. Oncogene 24: 6970-6975.
    • (2005) Oncogene , vol.24 , pp. 6970-6975
    • Papoutsaki, M.1    Moretti, F.2    Lanza, M.3    Marinari, B.4    Sartorelli, V.5    Guerrini, L.6    Chimenti, S.7    Levrero, M.8    Costanzo, A.9
  • 49
    • 0033549754 scopus 로고    scopus 로고
    • The biology of hair follicles
    • PAUS, R., COTSARELIS, G., (1999). The biology of hair follicles. N Engl J Med 341: 491-497.
    • (1999) N Engl J Med , vol.341 , pp. 491-497
    • Paus, R.1    Cotsarelis, G.2
  • 51
    • 0033104996 scopus 로고    scopus 로고
    • The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
    • PUTHALAKATH, H., HUANG, D.C., OREILLY, L.A., KING, S.M., STRASSER, A., (1999). The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell 3: 287-296.
    • (1999) Mol Cell , vol.3 , pp. 287-296
    • Puthalakath, H.1    Huang, D.C.2    Oreilly, L.A.3    King, S.M.4    Strasser, A.5
  • 52
    • 0035823238 scopus 로고    scopus 로고
    • Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
    • PUTHALAKATH, H., VILLUNGER, A., OREILLY, L.A., BEAUMONT, J.G., COULTAS, L., CHENEY, R.E., HUANG, D.C., STRASSER, A., (2001). Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 293: 1829-1832.
    • (2001) Science , vol.293 , pp. 1829-1832
    • Puthalakath, H.1    Villunger, A.2    Oreilly, L.A.3    Beaumont, J.G.4    Coultas, L.5    Cheney, R.E.6    Huang, D.C.7    Strasser, A.8
  • 55
    • 44449162944 scopus 로고    scopus 로고
    • The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation
    • RYGIEL, T.P., MERTENS, A.E., STRUMANE, K., VAN DER KAMMEN, R., COLLARD, J.G., (2008). The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation. J Cell Sci 121: 1183-1192.
    • (2008) J Cell Sci , vol.121 , pp. 1183-1192
    • Rygiel, T.P.1    Mertens, A.E.2    Strumane, K.3    Van Der Kammen, R.4    Collard, J.G.5
  • 56
    • 77649243897 scopus 로고    scopus 로고
    • The role of keratinocytes in defense against infection
    • SCHRODER, J.M., (2010). The role of keratinocytes in defense against infection. Curr Opin Infect Dis 23: 106-110.
    • (2010) Curr Opin Infect Dis , vol.23 , pp. 106-110
    • Schroder, J.M.1
  • 57
    • 0032477945 scopus 로고    scopus 로고
    • Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB
    • SEITZ, C.S., LIN, Q., DENG, H., KHAVARI, P.A., (1998). Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. Proc Natl Acad Sci USA 95: 2307-2312.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2307-2312
    • Seitz, C.S.1    Lin, Q.2    Deng, H.3    Khavari, P.A.4
  • 58
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • SHILOH, Y., (2003). ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 3: 155-168.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 59
    • 80051983081 scopus 로고    scopus 로고
    • Deconstructing the skin: Cytoarchitectural determinants of epidermal morphogenesis
    • SIMPSON, C.L., PATEL, D.M., GREEN, K.J., (2011). Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis. Nat Rev Mol Cell Biol.12: 565-580.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 565-580
    • Simpson, C.L.1    Patel, D.M.2    Green, K.J.3
  • 62
    • 85047697335 scopus 로고    scopus 로고
    • A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes
    • THORNBORROW, E.C., PATEL, S., MASTROPIETRO, A.E., SCHWARTZFARB, E.M., MANFREDI, J.J., (2002). A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes. Oncogene 21: 990-999.
    • (2002) Oncogene , vol.21 , pp. 990-999
    • Thornborrow, E.C.1    Patel, S.2    Mastropietro, A.E.3    Schwartzfarb, E.M.4    Manfredi, J.J.5
  • 63
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • VEIS, D.J., SORENSON, C.M., SHUTTER, J.R., KORSMEYER, S.J., (1993). Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75: 229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 64
    • 0028034199 scopus 로고
    • Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1
    • WAGNER, A.J., KOKONTIS, J.M., HAY, N., (1994). Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1. Genes Dev 8: 2817-2830.
    • (1994) Genes Dev , vol.8 , pp. 2817-2830
    • Wagner, A.J.1    Kokontis, J.M.2    Hay, N.3
  • 66
    • 27944493875 scopus 로고    scopus 로고
    • Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice
    • YANG, Z.Z., TSCHOPP, O., Di-Poi, N., BRUDER, E., BAUDRY, A., DUMMLER, B., WAHLI, W., HEMMINGS, B.A., (2005). Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice. Mol Cell Biol 25: 10407-10418.
    • (2005) Mol Cell Biol , vol.25 , pp. 10407-10418
    • Yang, Z.Z.1    Tschopp, O.2    Di-Poi, N.3    Bruder, E.4    Baudry, A.5    Dummler, B.6    Wahli, W.7    Hemmings, B.A.8
  • 67
    • 0346497823 scopus 로고    scopus 로고
    • NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK
    • ZHANG, J.Y., GREEN, C.L., TAO, S., KHAVARI, P.A., (2004). NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK. Genes Dev 18: 17-22.
    • (2004) Genes Dev , vol.18 , pp. 17-22
    • Zhang, J.Y.1    Green, C.L.2    Tao, S.3    Khavari, P.A.4
  • 68
    • 27744583471 scopus 로고    scopus 로고
    • Slugging it out: Fine tuning the p53-PUMA death connection
    • ZILFOU, J.T., SPECTOR, M.S., LOWE, S.W., (2005). Slugging it out: fine tuning the p53-PUMA death connection. Cell 123: 545-548
    • (2005) Cell , vol.123 , pp. 545-548
    • Zilfou, J.T.1    Spector, M.S.2    Lowe, S.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.