-
1
-
-
85047692516
-
Signalling pathways of the TNF superfamily: A double-edged sword
-
Aggarwal B.B. Signalling pathways of the TNF superfamily: A double-edged sword. Nat. Rev. Immunol. 3 (2003) 745-756
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 745-756
-
-
Aggarwal, B.B.1
-
2
-
-
34249879045
-
Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis
-
Algül H., Treiber M., Lesina M., Nakhai H., Saur D., Geisler F., Pfeifer A., Paxian S., and Schmid R.M. Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis. J. Clin. Invest. 117 (2007) 1490-1501
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1490-1501
-
-
Algül, H.1
Treiber, M.2
Lesina, M.3
Nakhai, H.4
Saur, D.5
Geisler, F.6
Pfeifer, A.7
Paxian, S.8
Schmid, R.M.9
-
3
-
-
0032729645
-
The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-γ, interleukin-2, and tumor necrosis factor-α, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: A type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients
-
Austin L.M., Ozawa M., Kikuchi T., Walters I.B., and Krueger J.G. The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-γ, interleukin-2, and tumor necrosis factor-α, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: A type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J. Invest. Dermatol. 113 (1999) 752-759
-
(1999)
J. Invest. Dermatol.
, vol.113
, pp. 752-759
-
-
Austin, L.M.1
Ozawa, M.2
Kikuchi, T.3
Walters, I.B.4
Krueger, J.G.5
-
4
-
-
25844505509
-
The genetics of psoriasis and autoimmunity
-
Bowcock A.M. The genetics of psoriasis and autoimmunity. Annu. Rev. Genomics Hum. Genet. 6 (2005) 93-122
-
(2005)
Annu. Rev. Genomics Hum. Genet.
, vol.6
, pp. 93-122
-
-
Bowcock, A.M.1
-
5
-
-
25444435193
-
Getting under the skin: The immunogenetics of psoriasis
-
Bowcock A.M., and Krueger J.G. Getting under the skin: The immunogenetics of psoriasis. Nat. Rev. Immunol. 5 (2005) 699-711
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 699-711
-
-
Bowcock, A.M.1
Krueger, J.G.2
-
6
-
-
0030973604
-
Transgenic mice expressing IFN-γ in the epidermis have eczema, hair hypopigmentation, and hair loss
-
Carroll J.M., Crompton T., Seery J.P., and Watt F.M. Transgenic mice expressing IFN-γ in the epidermis have eczema, hair hypopigmentation, and hair loss. J. Invest. Dermatol. 108 (1997) 412-422
-
(1997)
J. Invest. Dermatol.
, vol.108
, pp. 412-422
-
-
Carroll, J.M.1
Crompton, T.2
Seery, J.P.3
Watt, F.M.4
-
7
-
-
0029565083
-
Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis
-
Carroll J.M., Romero M.R., and Watt F.M. Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. Cell 83 (1995) 957-968
-
(1995)
Cell
, vol.83
, pp. 957-968
-
-
Carroll, J.M.1
Romero, M.R.2
Watt, F.M.3
-
8
-
-
0026770257
-
Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNFα transgenic mice
-
Cheng J., Turksen K., Yu Q.C., Schreiber H., Teng M., and Fuchs E. Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNFα transgenic mice. Genes Dev. 6 (1992) 1444-1456
-
(1992)
Genes Dev.
, vol.6
, pp. 1444-1456
-
-
Cheng, J.1
Turksen, K.2
Yu, Q.C.3
Schreiber, H.4
Teng, M.5
Fuchs, E.6
-
9
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
-
Clausen B.E., Burkhardt C., Reith W., Renkawitz R., and Förster I. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8 (1999) 265-277
-
(1999)
Transgenic Res.
, vol.8
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
Renkawitz, R.4
Förster, I.5
-
10
-
-
0028277665
-
Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin
-
De Togni P., Goellner J., Ruddle N.H., Streeter P.R., Fick A., Mariathasan S., Smith S.C., Carlson R., Shornick L.P., Strauss-Schoenberger J., et al. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 264 (1994) 703-707
-
(1994)
Science
, vol.264
, pp. 703-707
-
-
De Togni, P.1
Goellner, J.2
Ruddle, N.H.3
Streeter, P.R.4
Fick, A.5
Mariathasan, S.6
Smith, S.C.7
Carlson, R.8
Shornick, L.P.9
Strauss-Schoenberger, J.10
-
11
-
-
0037234390
-
Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease
-
Ghoreschi K., Thomas P., Breit S., Dugas M., Mailhammer R., van Eden W., van der Zee R., Biedermann T., Prinz J., Mack M., et al. Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease. Nat. Med. 9 (2003) 40-46
-
(2003)
Nat. Med.
, vol.9
, pp. 40-46
-
-
Ghoreschi, K.1
Thomas, P.2
Breit, S.3
Dugas, M.4
Mailhammer, R.5
van Eden, W.6
van der Zee, R.7
Biedermann, T.8
Prinz, J.9
Mack, M.10
-
13
-
-
4444376712
-
Signaling to NF-κB
-
Hayden M.S., and Ghosh S. Signaling to NF-κB. Genes Dev. 18 (2004) 2195-2224
-
(2004)
Genes Dev.
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
14
-
-
0029556979
-
T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl- transferase gene by site-directed recombination
-
Hennet T., Hagen F.K., Tabak L.A., and Marth J.D. T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl- transferase gene by site-directed recombination. Proc. Natl. Acad. Sci. USA 92 (1995) 12070-12074
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 12070-12074
-
-
Hennet, T.1
Hagen, F.K.2
Tabak, L.A.3
Marth, J.D.4
-
15
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-κB activity
-
Karin M., and Ben-Neriah Y. Phosphorylation meets ubiquitination: The control of NF-κB activity. Annu. Rev. Immunol. 18 (2000) 621-663
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
16
-
-
25844459154
-
NF-κB: Linking inflammation and immunity to cancer development and progression
-
Karin M., and Greten F.R. NF-κB: Linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 5 (2005) 749-759
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
17
-
-
0035116922
-
Interleukin-1 induces transcription of keratin K6 in human epidermal keratinocytes
-
Komine M., Rao L.S., Freedberg I.M., Simon M., Milisavljevic V., and Blumenberg M. Interleukin-1 induces transcription of keratin K6 in human epidermal keratinocytes. J. Invest. Dermatol. 116 (2001) 330-338
-
(2001)
J. Invest. Dermatol.
, vol.116
, pp. 330-338
-
-
Komine, M.1
Rao, L.S.2
Freedberg, I.M.3
Simon, M.4
Milisavljevic, V.5
Blumenberg, M.6
-
18
-
-
18144388730
-
Update on the mechanisms and efficacy of biological therapies for psoriasis
-
Koo J., and Khera P. Update on the mechanisms and efficacy of biological therapies for psoriasis. J. Dermatol. Sci. 38 (2005) 75-87
-
(2005)
J. Dermatol. Sci.
, vol.38
, pp. 75-87
-
-
Koo, J.1
Khera, P.2
-
19
-
-
18744387205
-
Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: Mice with inactivation of the entire TNF/LT locus versus single-knockout mice
-
Kuprash D.V., Alimzhanov M.B., Tumanov A.V., Grivennikov S.I., Shakhov A.N., Drutskaya L.N., Marino M.W., Turetskaya R.L., Anderson A.O., Rajewsky K., et al. Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: Mice with inactivation of the entire TNF/LT locus versus single-knockout mice. Mol. Cell. Biol. 22 (2002) 8626-8634
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 8626-8634
-
-
Kuprash, D.V.1
Alimzhanov, M.B.2
Tumanov, A.V.3
Grivennikov, S.I.4
Shakhov, A.N.5
Drutskaya, L.N.6
Marino, M.W.7
Turetskaya, R.L.8
Anderson, A.O.9
Rajewsky, K.10
-
20
-
-
20044385554
-
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease
-
Lang K.S., Recher M., Junt T., Navarini A.A., Harris N.L., Freigang S., Odermatt B., Conrad C., Ittner L.M., Bauer S., et al. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat. Med. 11 (2005) 138-145
-
(2005)
Nat. Med.
, vol.11
, pp. 138-145
-
-
Lang, K.S.1
Recher, M.2
Junt, T.3
Navarini, A.A.4
Harris, N.L.5
Freigang, S.6
Odermatt, B.7
Conrad, C.8
Ittner, L.M.9
Bauer, S.10
-
22
-
-
0036781052
-
NF-κB regulation in the immune system
-
Li Q., and Verma I.M. NF-κB regulation in the immune system. Nat. Rev. Immunol. 2 (2002) 725-734
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
23
-
-
0028245467
-
Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines
-
Nestle F.O., Turka L.A., and Nickoloff B.J. Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines. J. Clin. Invest. 94 (1994) 202-209
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 202-209
-
-
Nestle, F.O.1
Turka, L.A.2
Nickoloff, B.J.3
-
25
-
-
0029989339
-
Immune and inflammatory responses in TNFα-deficient mice: A critical requirement for TNFα in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response
-
Pasparakis M., Alexopoulou L., Episkopou V., and Kollias G. Immune and inflammatory responses in TNFα-deficient mice: A critical requirement for TNFα in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J. Exp. Med. 184 (1996) 1397-1411
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1397-1411
-
-
Pasparakis, M.1
Alexopoulou, L.2
Episkopou, V.3
Kollias, G.4
-
26
-
-
0037142027
-
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2
-
Pasparakis M., Courtois G., Hafner M., Schmidt-Supprian M., Nenci A., Toksoy A., Krampert M., Goebeler M., Gillitzer R., Israël A., et al. TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature 417 (2002) 861-866
-
(2002)
Nature
, vol.417
, pp. 861-866
-
-
Pasparakis, M.1
Courtois, G.2
Hafner, M.3
Schmidt-Supprian, M.4
Nenci, A.5
Toksoy, A.6
Krampert, M.7
Goebeler, M.8
Gillitzer, R.9
Israël, A.10
-
27
-
-
0037644804
-
Biological functions of tumor necrosis factor cytokines and their receptors
-
Pfeffer K. Biological functions of tumor necrosis factor cytokines and their receptors. Cytokine Growth Factor Rev. 14 (2003) 185-191
-
(2003)
Cytokine Growth Factor Rev.
, vol.14
, pp. 185-191
-
-
Pfeffer, K.1
-
28
-
-
0027297663
-
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
-
Pfeffer K., Matsuyama T., Kundig T.M., Wakeham A., Kishihara K., Shahinian A., Wiegmann K., Ohashi P.S., Kronke M., and Mak T.W. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73 (1993) 457-467
-
(1993)
Cell
, vol.73
, pp. 457-467
-
-
Pfeffer, K.1
Matsuyama, T.2
Kundig, T.M.3
Wakeham, A.4
Kishihara, K.5
Shahinian, A.6
Wiegmann, K.7
Ohashi, P.S.8
Kronke, M.9
Mak, T.W.10
-
29
-
-
0345504168
-
Inflammatory skin diseases, T cells, and immune surveillance
-
Robert C., and Kupper T.S. Inflammatory skin diseases, T cells, and immune surveillance. N. Engl. J. Med. 341 (1999) 1817-1828
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 1817-1828
-
-
Robert, C.1
Kupper, T.S.2
-
30
-
-
0034745388
-
p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes
-
Roper E., Weinberg W., Watt F.M., and Land H. p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes. EMBO Rep. 2 (2001) 145-150
-
(2001)
EMBO Rep.
, vol.2
, pp. 145-150
-
-
Roper, E.1
Weinberg, W.2
Watt, F.M.3
Land, H.4
-
31
-
-
20244364979
-
Stroma-mediated dysregulation of myelopoiesis in mice lacking IκBα
-
Rupec R.A., Jundt F., Rebholz B., Eckelt B., Weindl G., Herzinger T., Flaig M.J., Moosmann S., Plewig G., Dörken B., et al. Stroma-mediated dysregulation of myelopoiesis in mice lacking IκBα. Immunity 22 (2005) 479-491
-
(2005)
Immunity
, vol.22
, pp. 479-491
-
-
Rupec, R.A.1
Jundt, F.2
Rebholz, B.3
Eckelt, B.4
Weindl, G.5
Herzinger, T.6
Flaig, M.J.7
Moosmann, S.8
Plewig, G.9
Dörken, B.10
-
32
-
-
13444269249
-
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
-
Sano S., Chan K.S., Carbajal S., Clifford J., Peavey M., Kiguchi K., Itami S., Nickoloff B.J., and DiGiovanni J. Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nat. Med. 11 (2005) 43-49
-
(2005)
Nat. Med.
, vol.11
, pp. 43-49
-
-
Sano, S.1
Chan, K.S.2
Carbajal, S.3
Clifford, J.4
Peavey, M.5
Kiguchi, K.6
Itami, S.7
Nickoloff, B.J.8
DiGiovanni, J.9
-
33
-
-
0032908051
-
Animal models of psoriasis - what can we learn from them?
-
Schön M.P. Animal models of psoriasis - what can we learn from them?. J. Invest. Dermatol. 112 (1999) 405-410
-
(1999)
J. Invest. Dermatol.
, vol.112
, pp. 405-410
-
-
Schön, M.P.1
-
34
-
-
0029566108
-
A cre-transgenic mouse strain for the ubiquitous deletion of loxP- flanked gene segments including deletion in germ cells
-
Schwenk F., Baron U., and Rajewsky K. A cre-transgenic mouse strain for the ubiquitous deletion of loxP- flanked gene segments including deletion in germ cells. Nucleic Acids Res. 23 (1995) 5080-5081
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 5080-5081
-
-
Schwenk, F.1
Baron, U.2
Rajewsky, K.3
-
35
-
-
0030825272
-
Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development
-
Tarutani M., Itami S., Okabe M., Ikawa M., Tezuka T., Yoshikawa K., Kinoshita T., and Takeda J. Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development. Proc. Natl. Acad. Sci. USA 94 (1997) 7400-7405
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7400-7405
-
-
Tarutani, M.1
Itami, S.2
Okabe, M.3
Ikawa, M.4
Tezuka, T.5
Yoshikawa, K.6
Kinoshita, T.7
Takeda, J.8
-
36
-
-
11844269840
-
Phosphorylation of NF-κB and IκB proteins: Implications in cancer and inflammation
-
Viatour P., Merville M.P., Bours V., and Chariot A. Phosphorylation of NF-κB and IκB proteins: Implications in cancer and inflammation. Trends Biochem. Sci. 30 (2005) 43-52
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 43-52
-
-
Viatour, P.1
Merville, M.P.2
Bours, V.3
Chariot, A.4
-
37
-
-
0029861579
-
Dermal injection of immunocytes induces psoriasis
-
Wrone-Smith T., and Nickoloff B.J. Dermal injection of immunocytes induces psoriasis. J. Clin. Invest. 98 (1996) 1878-1887
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1878-1887
-
-
Wrone-Smith, T.1
Nickoloff, B.J.2
-
38
-
-
0346497823
-
NF-κB RelA opposes epidermal proliferation driven by TNFR1 and JNK
-
Zhang J.Y., Green C.L., Tao S., and Khavari P.A. NF-κB RelA opposes epidermal proliferation driven by TNFR1 and JNK. Genes Dev. 18 (2004) 17-22
-
(2004)
Genes Dev.
, vol.18
, pp. 17-22
-
-
Zhang, J.Y.1
Green, C.L.2
Tao, S.3
Khavari, P.A.4
|