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Volumn 18, Issue 1, 2004, Pages 17-22

NF-κB RelA opposes epidermal proliferation driven by TNFR1 and JNK

Author keywords

Differentiation; Epidermis; NF B; Proliferation

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR RECEPTOR 1; DNA BINDING PROTEIN; LEUKOCYTE ANTIGEN; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 0346497823     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1160904     Document Type: Article
Times cited : (121)

References (37)
  • 1
    • 0033764665 scopus 로고    scopus 로고
    • Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-κB
    • Aggarwal, B.B. 2000. Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-κB. Ann. Rheum. Dis. 59 Suppl 1: i6-i16.
    • (2000) Ann. Rheum. Dis. , vol.59 , Issue.SUPPL. 1
    • Aggarwal, B.B.1
  • 2
    • 0035424999 scopus 로고    scopus 로고
    • Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-κB in leukocyte recruitment
    • Alcamo, E., Mizgerd, J.P., Horwitz, B.H., Bronson, R., Beg, A.A., Scott, M., Doerschuk, C.M., Hynes, R.O., and Baltimore, D. 2001. Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-κB in leukocyte recruitment. J. Immunol. 167: 1592-1600.
    • (2001) J. Immunol. , vol.167 , pp. 1592-1600
    • Alcamo, E.1    Mizgerd, J.P.2    Horwitz, B.H.3    Bronson, R.4    Beg, A.A.5    Scott, M.6    Doerschuk, C.M.7    Hynes, R.O.8    Baltimore, D.9
  • 3
    • 0037392942 scopus 로고    scopus 로고
    • The specificities of protein kinase inhibitors: An update
    • Bain, J., McLauchlan, H., Elliott, M., and Cohen, P. 2003. The specificities of protein kinase inhibitors: An update. Biochem. J. 371: 199-204.
    • (2003) Biochem. J. , vol.371 , pp. 199-204
    • Bain, J.1    McLauchlan, H.2    Elliott, M.3    Cohen, P.4
  • 4
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
    • Beg, A.A., Sha, W.C., Bronson, R.T., Ghosh, S., and Baltimore, D. 1995. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB. Nature 376: 167-170.
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 6
    • 0029906097 scopus 로고    scopus 로고
    • Corrective gene transfer in the human skin disorder lamellar ichthyosis
    • Choate, K.A., Medalie, D.A., Morgan, J.R., and Khavari, P.A. 1996. Corrective gene transfer in the human skin disorder lamellar ichthyosis. Nat. Med. 2: 1263-1267.
    • (1996) Nat. Med. , vol.2 , pp. 1263-1267
    • Choate, K.A.1    Medalie, D.A.2    Morgan, J.R.3    Khavari, P.A.4
  • 8
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard, B., Hibi, M., Wu, I.H., Barrett, T., Su, B., Deng, T., Karin, M., and Davis, R.J. 1994. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 10
    • 0037184348 scopus 로고    scopus 로고
    • NF-κB signaling. Many roads lead to madrid
    • Dixit, V. and Mak, T.W. 2002. NF-κB signaling. Many roads lead to madrid. Cell 111: 615-619.
    • (2002) Cell , vol.111 , pp. 615-619
    • Dixit, V.1    Mak, T.W.2
  • 11
    • 0031964855 scopus 로고    scopus 로고
    • Mice deficient in nuclear factor (NF)-κ B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture
    • Franzoso, G., Carlson, L., Poljak, L., Shores, E.W., Epstein, S., Leonardi, A., Grinberg, A., Tran, T., Scharton-Kerstcn, T., Anver, M., et al. 1998. Mice deficient in nuclear factor (NF)-κ B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture. J. Exp. Med. 187: 147-159.
    • (1998) J. Exp. Med. , vol.187 , pp. 147-159
    • Franzoso, G.1    Carlson, L.2    Poljak, L.3    Shores, E.W.4    Epstein, S.5    Leonardi, A.6    Grinberg, A.7    Tran, T.8    Scharton-Kerstcn, T.9    Anver, M.10
  • 12
    • 0036245242 scopus 로고    scopus 로고
    • Getting under the skin of epidermal morphogenesis
    • Fuchs, E. and Raghavan, S. 2002. Getting under the skin of epidermal morphogenesis. Nat. Rev. Genet. 3: 199-209.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 199-209
    • Fuchs, E.1    Raghavan, S.2
  • 13
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • Ghosh, S. and Karin, M. 2002. Missing pieces in the NF-κB puzzle. Cell 109 Suppl: S81-S96.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Ghosh, S.1    Karin, M.2
  • 14
    • 0038757747 scopus 로고    scopus 로고
    • The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair
    • Hayakawa, J., Depatie, C., Ohmichi, M., and Mercola, D. 2003. The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair. J. Biol. Chem. 278: 20582-20592.
    • (2003) J. Biol. Chem. , vol.278 , pp. 20582-20592
    • Hayakawa, J.1    Depatie, C.2    Ohmichi, M.3    Mercola, D.4
  • 15
    • 0037417129 scopus 로고    scopus 로고
    • Divergent gene regulation and growth effects by NF-κB in epithelial and mesenchymal cells of human skin
    • Hinata, K., Gervin, A.M., Zhang, J.Y., and Khavari, P.A. 2003. Divergent gene regulation and growth effects by NF-κB in epithelial and mesenchymal cells of human skin. Oncogene 22: 1955-1964.
    • (2003) Oncogene , vol.22 , pp. 1955-1964
    • Hinata, K.1    Gervin, A.M.2    Zhang, J.Y.3    Khavari, P.A.4
  • 16
    • 0033537767 scopus 로고    scopus 로고
    • Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase
    • Hu, Y., Baud, V., Delhase, M., Zhang, P., Deerinck, T., Ellisman, M., Johnson, R., and Karin, M. 1999. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase. Science 284: 316-320.
    • (1999) Science , vol.284 , pp. 316-320
    • Hu, Y.1    Baud, V.2    Delhase, M.3    Zhang, P.4    Deerinck, T.5    Ellisman, M.6    Johnson, R.7    Karin, M.8
  • 17
    • 0035809983 scopus 로고    scopus 로고
    • IKKα controls formation of the epidermis independently of NF-κB
    • Hu, Y., Baud, V., Oga, T., Kim, K.I., Yoshida, K., and Karin, M. 2001. IKKα controls formation of the epidermis independently of NF-κB. Nature 410: 710-714.
    • (2001) Nature , vol.410 , pp. 710-714
    • Hu, Y.1    Baud, V.2    Oga, T.3    Kim, K.I.4    Yoshida, K.5    Karin, M.6
  • 18
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson, G.L. and Lapadat, R. 2002. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298: 1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 19
    • 0025677334 scopus 로고
    • Human keratinocytes are a source for tumor necrosis factor α: Evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light
    • Kock, A., Schwarz, T., Kirnbauer, R., Urbanski, A., Perry, P., Ansel, J.C., and Luger, T.A. 1990. Human keratinocytes are a source for tumor necrosis factor α: Evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J. Exp. Med. 172: 1609-1614.
    • (1990) J. Exp. Med. , vol.172 , pp. 1609-1614
    • Kock, A.1    Schwarz, T.2    Kirnbauer, R.3    Urbanski, A.4    Perry, P.5    Ansel, J.C.6    Luger, T.A.7
  • 20
    • 0029150389 scopus 로고
    • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
    • Kontgen, F., Grumont, R.J., Strasser, A., Metcalf, D., Li, R., Tarlinton, D., and Gerondakis, S. 1995. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes & Dev. 9: 1965-1977.
    • (1995) Genes & Dev. , vol.9 , pp. 1965-1977
    • Kontgen, F.1    Grumont, R.J.2    Strasser, A.3    Metcalf, D.4    Li, R.5    Tarlinton, D.6    Gerondakis, S.7
  • 21
    • 0037159513 scopus 로고    scopus 로고
    • IKKα, IKKβ, and NEMO/IKKγ, are each required for the NF-κ B-mediated inflammatory response program
    • Li, X., Massa, P.E., Hanidu, A., Peet, G.W., Aro, P., Savitt, A., Mische, S., Li, J., and Marcu, K.B. 2002. IKKα, IKKβ, and NEMO/IKKγ, are each required for the NF-κ B-mediated inflammatory response program. J. Biol. Chem. 277: 45129-45140.
    • (2002) J. Biol. Chem. , vol.277 , pp. 45129-45140
    • Li, X.1    Massa, P.E.2    Hanidu, A.3    Peet, G.W.4    Aro, P.5    Savitt, A.6    Mische, S.7    Li, J.8    Marcu, K.B.9
  • 22
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
    • Liu, Z.G., Hsu, H., Goeddel, D.V., and Karin, M. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87: 565-576.
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 23
    • 0033634663 scopus 로고    scopus 로고
    • Female mice heterozygous for IKK γ/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
    • Makris, C., Godfrey, V.L., Krahn-Senftleben, G., Takahashi, T., Roberts, J.L., Schwarz, T., Feng, L., Johnson, R.S., and Karin, M. 2000. Female mice heterozygous for IKK γ/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol. Cell 5: 969-979.
    • (2000) Mol. Cell , vol.5 , pp. 969-979
    • Makris, C.1    Godfrey, V.L.2    Krahn-Senftleben, G.3    Takahashi, T.4    Roberts, J.L.5    Schwarz, T.6    Feng, L.7    Johnson, R.S.8    Karin, M.9
  • 27
    • 0035942278 scopus 로고    scopus 로고
    • In vivo restoration of laminin 5 β 3 expression and function in junctional epidermolysis bullosa
    • Robbins, P.B., Lin, Q., Goodnough, J.B., Tian, H., Chen, X., and Khavari, P.A. 2001. In vivo restoration of laminin 5 β 3 expression and function in junctional epidermolysis bullosa. Proc. Natl. Acad. Sci. 98: 5193-5198.
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 5193-5198
    • Robbins, P.B.1    Lin, Q.2    Goodnough, J.B.3    Tian, H.4    Chen, X.5    Khavari, P.A.6
  • 28
    • 0033873796 scopus 로고    scopus 로고
    • Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice
    • Rosenfeld, M.E., Prichard, L., Shiojiri, N., and Fausto, N. 2000. Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice. Am. J. Pathol. 156: 997-1007.
    • (2000) Am. J. Pathol. , vol.156 , pp. 997-1007
    • Rosenfeld, M.E.1    Prichard, L.2    Shiojiri, N.3    Fausto, N.4
  • 30
    • 0032477945 scopus 로고    scopus 로고
    • Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB
    • Seitz, C.S., Lin, Q., Deng, H., and Khavari, P.A. 1998. Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB. Proc. Natl. Acad. Sci. 95: 2307-2312.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 2307-2312
    • Seitz, C.S.1    Lin, Q.2    Deng, H.3    Khavari, P.A.4
  • 31
    • 0033624673 scopus 로고    scopus 로고
    • Nuclear factor κB subunits induce epithelial cell growth arrest
    • Seitz, C.S., Deng, H., Hinata, K., Lin, Q., and Khavari, P.A. 2000a. Nuclear factor κB subunits induce epithelial cell growth arrest. Cancer Res. 60: 4085-4092.
    • (2000) Cancer Res. , vol.60 , pp. 4085-4092
    • Seitz, C.S.1    Deng, H.2    Hinata, K.3    Lin, Q.4    Khavari, P.A.5
  • 32
    • 0033621589 scopus 로고    scopus 로고
    • NF-κB determines localization and features of cell death in epidermis
    • Seitz, C.S., Freiberg, R.A., Hinata, K., and Khavari, P.A. 2000b. NF-κB determines localization and features of cell death in epidermis. J. Clin. Invest. 105: 253-260.
    • (2000) J. Clin. Invest. , vol.105 , pp. 253-260
    • Seitz, C.S.1    Freiberg, R.A.2    Hinata, K.3    Khavari, P.A.4
  • 33
    • 0028804551 scopus 로고
    • Targeted disruption of the p50 subunit of NF-κ B leads to multifocal defects in immune responses
    • Sha, W.C., Liou, H.C., Tuomanen, E.I., and Baltimore, D. 1995. Targeted disruption of the p50 subunit of NF-κ B leads to multifocal defects in immune responses. Cell 80: 321-330.
    • (1995) Cell , vol.80 , pp. 321-330
    • Sha, W.C.1    Liou, H.C.2    Tuomanen, E.I.3    Baltimore, D.4
  • 36
    • 0033565763 scopus 로고    scopus 로고
    • Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-κB signaling
    • van Hogerlinden, M., Rozell, B.L., Ahrlund-Richter, L., and Toftgard, R. 1999. Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-κB signaling. Cancer Res. 59: 3299-3303.
    • (1999) Cancer Res. , vol.59 , pp. 3299-3303
    • Van Hogerlinden, M.1    Rozell, B.L.2    Ahrlund-Richter, L.3    Toftgard, R.4
  • 37
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κ B/Rel family
    • Weih, F., Carrasco, D., Durham, S.K., Barton, D.S., Rizzo, C.A., Ryseck, R.P., Lira, S.A., and Bravo, R. 1995. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κ B/Rel family. Cell 80: 331-340.
    • (1995) Cell , vol.80 , pp. 331-340
    • Weih, F.1    Carrasco, D.2    Durham, S.K.3    Barton, D.S.4    Rizzo, C.A.5    Ryseck, R.P.6    Lira, S.A.7    Bravo, R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.