메뉴 건너뛰기




Volumn 89, Issue 9, 2015, Pages 1569-1578

Activation of sterol regulatory element-binding proteins in mice exposed to perfluorooctanoic acid for 28 days

Author keywords

Lipid metabolism; Perfluorononanoic acid; PPAR; SREBP

Indexed keywords

CHOLESTEROL; MESSENGER RNA; PERFLUOROOCTANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN; FLUOROCARBON; MICRORNA; MIRN182 MICRORNA, MOUSE; MIRN183 MICRORNA, MOUSE; MIRN96 MICRORNA, MOUSE; OCTANOIC ACID DERIVATIVE;

EID: 84940611926     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1322-7     Document Type: Article
Times cited : (46)

References (35)
  • 1
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • COI: 1:CAS:528:DC%2BD1MXhs1Kiuro%3D, PID: 19167326
    • Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136(2):215–233
    • (2009) Cell , vol.136 , Issue.2 , pp. 215-233
    • Bartel, D.P.1
  • 2
    • 33847709027 scopus 로고    scopus 로고
    • SREBP in signal transduction: cholesterol metabolism and beyond
    • COI: 1:CAS:528:DC%2BD2sXjt1Sksr0%3D, PID: 17303406
    • Bengoechea-Alonso MT, Ericsson J (2007) SREBP in signal transduction: cholesterol metabolism and beyond. Curr Opin Cell Biol 19(2):215–222
    • (2007) Curr Opin Cell Biol , vol.19 , Issue.2 , pp. 215-222
    • Bengoechea-Alonso, M.T.1    Ericsson, J.2
  • 3
    • 79961024699 scopus 로고    scopus 로고
    • Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes
    • COI: 1:CAS:528:DC%2BC3MXpvFSqs7c%3D, PID: 21723365
    • Bjork JA, Butenhoff JL, Wallace KB (2011) Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes. Toxicology 288(1–3):8–17
    • (2011) Toxicology , vol.288 , Issue.1-3 , pp. 8-17
    • Bjork, J.A.1    Butenhoff, J.L.2    Wallace, K.B.3
  • 4
    • 84883488437 scopus 로고    scopus 로고
    • MicroRNAs and metabolism crosstalk in energy homeostasis
    • COI: 1:CAS:528:DC%2BC3sXhtV2rsL%2FI, PID: 23850315
    • Dumortier O, Hinault C, Van Obberghen E (2013) MicroRNAs and metabolism crosstalk in energy homeostasis. Cell Metab 18(3):312–324
    • (2013) Cell Metab , vol.18 , Issue.3 , pp. 312-324
    • Dumortier, O.1    Hinault, C.2    Van Obberghen, E.3
  • 5
    • 84866548567 scopus 로고    scopus 로고
    • Kupffer cells suppress perfluorononanoic acid-induced hepatic peroxisome proliferator-activated receptor alpha expression by releasing cytokines
    • COI: 1:CAS:528:DC%2BC38XnvVSitb8%3D, PID: 22648072
    • Fang X, Zou S, Zhao Y et al (2012) Kupffer cells suppress perfluorononanoic acid-induced hepatic peroxisome proliferator-activated receptor alpha expression by releasing cytokines. Arch Toxicol 86(10):1515–1525
    • (2012) Arch Toxicol , vol.86 , Issue.10 , pp. 1515-1525
    • Fang, X.1    Zou, S.2    Zhao, Y.3
  • 6
    • 79958716078 scopus 로고    scopus 로고
    • Human SREBP1c expression in liver is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha)
    • COI: 1:CAS:528:DC%2BC3MXntlOrsr8%3D, PID: 21540177
    • Fernandez-Alvarez A, Alvarez MS, Gonzalez R, Cucarella C, Muntane J, Casado M (2011) Human SREBP1c expression in liver is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha). J Biol Chem 286(24):21466–21477
    • (2011) J Biol Chem , vol.286 , Issue.24 , pp. 21466-21477
    • Fernandez-Alvarez, A.1    Alvarez, M.S.2    Gonzalez, R.3    Cucarella, C.4    Muntane, J.5    Casado, M.6
  • 7
    • 84878791042 scopus 로고    scopus 로고
    • Concurrent activation of liver X receptor and peroxisome proliferator-activated receptor alpha exacerbates hepatic steatosis in high fat diet-induced obese mice
    • COI: 1:CAS:528:DC%2BC3sXhtVSku7%2FK, PID: 23762402
    • Gao M, Bu L, Ma Y, Liu D (2013) Concurrent activation of liver X receptor and peroxisome proliferator-activated receptor alpha exacerbates hepatic steatosis in high fat diet-induced obese mice. PLoS ONE 8(6):e65641
    • (2013) PLoS ONE , vol.8 , Issue.6 , pp. 65641
    • Gao, M.1    Bu, L.2    Ma, Y.3    Liu, D.4
  • 8
    • 0026775827 scopus 로고
    • The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid
    • COI: 1:CAS:528:DyaK3sXlt1ajtA%3D%3D, PID: 1327145
    • Haughom B, Spydevold O (1992) The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid. Biochim Biophys Acta 1128(1):65–72
    • (1992) Biochim Biophys Acta , vol.1128 , Issue.1 , pp. 65-72
    • Haughom, B.1    Spydevold, O.2
  • 9
    • 0036864411 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis
    • COI: 1:CAS:528:DC%2BD38XovF2itrs%3D
    • Horton JD (2002) Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis. Biochem Soc T 30:1091–1095
    • (2002) Biochem Soc T , vol.30 , pp. 1091-1095
    • Horton, J.D.1
  • 10
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • COI: 1:CAS:528:DC%2BD38XjsFals7c%3D, PID: 11994399
    • Horton JD, Goldstein JL, Brown MS (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109(9):1125–1131
    • (2002) J Clin Invest , vol.109 , Issue.9 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 11
    • 84856471735 scopus 로고    scopus 로고
    • SREBPs: metabolic integrators in physiology and metabolism
    • COI: 1:CAS:528:DC%2BC38XhvVCntLg%3D, PID: 22154484
    • Jeon TI, Osborne TF (2012) SREBPs: metabolic integrators in physiology and metabolism. Trends Endocrinol Metab 23(2):65–72
    • (2012) Trends Endocrinol Metab , vol.23 , Issue.2 , pp. 65-72
    • Jeon, T.I.1    Osborne, T.F.2
  • 12
    • 84879852051 scopus 로고    scopus 로고
    • An SREBP-responsive microRNA operon contributes to a regulatory loop for intracellular lipid homeostasis
    • COI: 1:CAS:528:DC%2BC3sXhtVGrtrnN, PID: 23823476
    • Jeon TI, Esquejo RM, Roqueta-Rivera M et al (2013) An SREBP-responsive microRNA operon contributes to a regulatory loop for intracellular lipid homeostasis. Cell Metab 18(1):51–61
    • (2013) Cell Metab , vol.18 , Issue.1 , pp. 51-61
    • Jeon, T.I.1    Esquejo, R.M.2    Roqueta-Rivera, M.3
  • 13
    • 1242311734 scopus 로고    scopus 로고
    • The toxicology of perfluorooctanoate
    • COI: 1:CAS:528:DC%2BD2cXlslSgsbo%3D, PID: 15328768
    • Kennedy GL Jr, Butenhoff JL, Olsen GW et al (2004) The toxicology of perfluorooctanoate. Crit Rev Toxicol 34(4):351–384
    • (2004) Crit Rev Toxicol , vol.34 , Issue.4 , pp. 351-384
    • Kennedy, G.L.1    Butenhoff, J.L.2    Olsen, G.W.3
  • 14
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • COI: 1:CAS:528:DC%2BD3cXjslymsb4%3D, PID: 10839530
    • Kersten S, Desvergne B, Wahli W (2000) Roles of PPARs in health and disease. Nature 405(6785):421–424
    • (2000) Nature , vol.405 , Issue.6785 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 15
    • 22544473888 scopus 로고    scopus 로고
    • A role for PPARalpha in the control of SREBP activity and lipid synthesis in the liver
    • COI: 1:CAS:528:DC%2BD2MXmtVSmsrg%3D, PID: 15777286
    • Knight BL, Hebbachi A, Hauton D et al (2005) A role for PPARalpha in the control of SREBP activity and lipid synthesis in the liver. Biochem J 389(Pt 2):413–421
    • (2005) Biochem J , vol.389 , pp. 413-421
    • Knight, B.L.1    Hebbachi, A.2    Hauton, D.3
  • 16
    • 60349084474 scopus 로고    scopus 로고
    • Activation of PPAR alpha and PPAR gamma reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1
    • PID: 19248225
    • Konig B, Koch A, Spielmann J et al (2009) Activation of PPAR alpha and PPAR gamma reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1. Eur J Pharmacol 605(1–3):23–30
    • (2009) Eur J Pharmacol , vol.605 , Issue.1-3 , pp. 23-30
    • Konig, B.1    Koch, A.2    Spielmann, J.3
  • 17
    • 0033033908 scopus 로고    scopus 로고
    • Alterations by perfluorooctanoic acid of glycerolipid metabolism in rat liver
    • COI: 1:CAS:528:DyaK1MXhsVWnsL0%3D, PID: 10227579
    • Kudo N, Mizuguchi H, Yamamoto A, Kawashima Y (1999) Alterations by perfluorooctanoic acid of glycerolipid metabolism in rat liver. Chem Biol Interact 118(1):69–83
    • (1999) Chem Biol Interact , vol.118 , Issue.1 , pp. 69-83
    • Kudo, N.1    Mizuguchi, H.2    Yamamoto, A.3    Kawashima, Y.4
  • 18
    • 36049021902 scopus 로고    scopus 로고
    • Perfluoroalkyl acids: a review of monitoring and toxicological findings
    • COI: 1:CAS:528:DC%2BD2sXhtFKru7%2FI, PID: 17519394
    • Lau C, Anitole K, Hodes C, Lai D, Pfahles-Hutchens A, Seed J (2007) Perfluoroalkyl acids: a review of monitoring and toxicological findings. Toxicol Sci 99(2):366–394
    • (2007) Toxicol Sci , vol.99 , Issue.2 , pp. 366-394
    • Lau, C.1    Anitole, K.2    Hodes, C.3    Lai, D.4    Pfahles-Hutchens, A.5    Seed, J.6
  • 19
    • 0035873619 scopus 로고    scopus 로고
    • SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation
    • COI: 1:CAS:528:DC%2BD3MXktVans7w%3D, PID: 11358865
    • Matsuda M, Korn BS, Hammer RE et al (2001) SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation. Gene Dev 15(10):1206–1216
    • (2001) Gene Dev , vol.15 , Issue.10 , pp. 1206-1216
    • Matsuda, M.1    Korn, B.S.2    Hammer, R.E.3
  • 20
    • 77249135053 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor-alpha in hepatobiliary injury induced by ammonium perfluorooctanoate in mouse liver
    • COI: 1:CAS:528:DC%2BC3cXivFejtbg%3D, PID: 20160413
    • Minata M, Harada KH, Karrman A et al (2010) Role of peroxisome proliferator-activated receptor-alpha in hepatobiliary injury induced by ammonium perfluorooctanoate in mouse liver. Ind Health 48(1):96–107
    • (2010) Ind Health , vol.48 , Issue.1 , pp. 96-107
    • Minata, M.1    Harada, K.H.2    Karrman, A.3
  • 21
    • 0035424456 scopus 로고    scopus 로고
    • CREating a SCAP-less liver keeps SREBPs pinned in the ER membrane and prevents increased lipid synthesis in response to low cholesterol and high insulin
    • COI: 1:CAS:528:DC%2BD3MXlvFertr4%3D, PID: 11485982
    • Osborne TF (2001) CREating a SCAP-less liver keeps SREBPs pinned in the ER membrane and prevents increased lipid synthesis in response to low cholesterol and high insulin. Gene Dev 15(15):1873–1878
    • (2001) Gene Dev , vol.15 , Issue.15 , pp. 1873-1878
    • Osborne, T.F.1
  • 22
    • 77954987061 scopus 로고    scopus 로고
    • PPARalpha: energy combustion, hypolipidemia, inflammation and cancer
    • PID: 20414453
    • Pyper SR, Viswakarma N, Yu S, Reddy JK (2010) PPARalpha: energy combustion, hypolipidemia, inflammation and cancer. Nucl Recept Signal 8:e002
    • (2010) Nucl Recept Signal , vol.8 , pp. 2
    • Pyper, S.R.1    Viswakarma, N.2    Yu, S.3    Reddy, J.K.4
  • 23
    • 39849083646 scopus 로고    scopus 로고
    • SREBPs: the crossroads of physiological and pathological lipid homeostasis
    • COI: 1:CAS:528:DC%2BD1cXjtVCjsrY%3D, PID: 18291668
    • Raghow R, Yellaturu C, Deng X, Park EA, Elam MB (2008) SREBPs: the crossroads of physiological and pathological lipid homeostasis. Trends Endocrinol Metab 19(2):65–73
    • (2008) Trends Endocrinol Metab , vol.19 , Issue.2 , pp. 65-73
    • Raghow, R.1    Yellaturu, C.2    Deng, X.3    Park, E.A.4    Elam, M.B.5
  • 24
    • 42149128919 scopus 로고    scopus 로고
    • Gene profiling in the livers of wild-type and PPARalpha-null mice exposed to perfluorooctanoic acid
    • COI: 1:CAS:528:DC%2BD1cXnslKhsL8%3D, PID: 18467677
    • Rosen MB, Abbott BD, Wolf DC et al (2008a) Gene profiling in the livers of wild-type and PPARalpha-null mice exposed to perfluorooctanoic acid. Toxicol Pathol 36(4):592–607
    • (2008) Toxicol Pathol , vol.36 , Issue.4 , pp. 592-607
    • Rosen, M.B.1    Abbott, B.D.2    Wolf, D.C.3
  • 25
    • 42149137870 scopus 로고    scopus 로고
    • Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR
    • COI: 1:CAS:528:DC%2BD1cXksF2ls78%3D, PID: 18281256
    • Rosen MB, Lee JS, Ren H et al (2008b) Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR. Toxicol Sci 103(1):46–56
    • (2008) Toxicol Sci , vol.103 , Issue.1 , pp. 46-56
    • Rosen, M.B.1    Lee, J.S.2    Ren, H.3
  • 26
    • 78349298325 scopus 로고    scopus 로고
    • Gene Expression Profiling in Wild-Type and PPARalpha-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARalpha-Independent Effects
    • 794739
    • Rosen MB, Schmid JR, Corton JC, et al. (2010) Gene Expression Profiling in Wild-Type and PPARalpha-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARalpha-Independent Effects. PPAR Res 2010, 794739
    • (2010) PPAR Res 2010, pii
    • Rosen, M.B.1    Schmid, J.R.2    Corton, J.C.3
  • 27
    • 84861878591 scopus 로고    scopus 로고
    • Perfluorooctanoic acid affects the activity of the hepatocyte nuclear factor 4 alpha (HNF4alpha)
    • COI: 1:CAS:528:DC%2BC38XpsVyju7c%3D, PID: 22609092
    • Scharmach E, Buhrke T, Lichtenstein D, Lampen A (2012) Perfluorooctanoic acid affects the activity of the hepatocyte nuclear factor 4 alpha (HNF4alpha). Toxicol Lett 212(2):106–112
    • (2012) Toxicol Lett , vol.212 , Issue.2 , pp. 106-112
    • Scharmach, E.1    Buhrke, T.2    Lichtenstein, D.3    Lampen, A.4
  • 28
    • 84867099976 scopus 로고    scopus 로고
    • Expanding roles for SREBP in metabolism
    • COI: 1:CAS:528:DC%2BC38Xhtl2ksbrK, PID: 23000402
    • Shao W, Espenshade PJ (2012) Expanding roles for SREBP in metabolism. Cell Metab 16(4):414–419
    • (2012) Cell Metab , vol.16 , Issue.4 , pp. 414-419
    • Shao, W.1    Espenshade, P.J.2
  • 29
    • 33845609258 scopus 로고    scopus 로고
    • Activation of mouse and human peroxisome proliferator-activated receptors (alpha, beta/delta, gamma) by perfluorooctanoic acid and perfluorooctane sulfonate
    • COI: 1:CAS:528:DC%2BD28XhtlChtLbO, PID: 17047030
    • Takacs ML, Abbott BD (2007) Activation of mouse and human peroxisome proliferator-activated receptors (alpha, beta/delta, gamma) by perfluorooctanoic acid and perfluorooctane sulfonate. Toxicol Sci 95(1):108–117
    • (2007) Toxicol Sci , vol.95 , Issue.1 , pp. 108-117
    • Takacs, M.L.1    Abbott, B.D.2
  • 30
    • 84876551716 scopus 로고    scopus 로고
    • High fat diet feeding exaggerates perfluorooctanoic acid-induced liver injury in mice via modulating multiple metabolic pathways
    • COI: 1:CAS:528:DC%2BC3sXntVKrtrs%3D, PID: 23626681
    • Tan X, Xie G, Sun X et al (2013) High fat diet feeding exaggerates perfluorooctanoic acid-induced liver injury in mice via modulating multiple metabolic pathways. PLoS ONE 8(4):e61409
    • (2013) PLoS ONE , vol.8 , Issue.4 , pp. 61409
    • Tan, X.1    Xie, G.2    Sun, X.3
  • 31
    • 79958244231 scopus 로고    scopus 로고
    • PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
    • COI: 1:CAS:528:DC%2BC3MXnsVOktLw%3D, PID: 21382489
    • Varga T, Czimmerer Z, Nagy L (2011) PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation. Biochim Biophys Acta 1812(8):1007–1022
    • (2011) Biochim Biophys Acta , vol.1812 , Issue.8 , pp. 1007-1022
    • Varga, T.1    Czimmerer, Z.2    Nagy, L.3
  • 32
    • 84860821984 scopus 로고    scopus 로고
    • PFOS-induced hepatic steatosis, the mechanistic actions on beta-oxidation and lipid transport
    • COI: 1:CAS:528:DC%2BC38XnslSms7w%3D, PID: 22484034
    • Wan HT, Zhao YG, Wei X, Hui KY, Giesy JP, Wong CK (2012) PFOS-induced hepatic steatosis, the mechanistic actions on beta-oxidation and lipid transport. Biochim Biophys Acta 1820(7):1092–1101
    • (2012) Biochim Biophys Acta , vol.1820 , Issue.7 , pp. 1092-1101
    • Wan, H.T.1    Zhao, Y.G.2    Wei, X.3    Hui, K.Y.4    Giesy, J.P.5    Wong, C.K.6
  • 33
    • 42149146829 scopus 로고    scopus 로고
    • Comparative hepatic effects of perfluorooctanoic acid and WY 14,643 in PPAR-alpha knockout and wild-type mice
    • COI: 1:CAS:528:DC%2BD1cXnslKhsLk%3D, PID: 18467680
    • Wolf DC, Moore T, Abbott BD et al (2008) Comparative hepatic effects of perfluorooctanoic acid and WY 14,643 in PPAR-alpha knockout and wild-type mice. Toxicol Pathol 36(4):632–639
    • (2008) Toxicol Pathol , vol.36 , Issue.4 , pp. 632-639
    • Wolf, D.C.1    Moore, T.2    Abbott, B.D.3
  • 34
    • 84887539888 scopus 로고    scopus 로고
    • Circulating MicroRNA profiles altered in mice after 28 days exposure to perfluorooctanoic acid
    • COI: 1:CAS:528:DC%2BC3sXhvFOks7%2FJ, PID: 24459700
    • Yan S, Wang J, Zhang W, Dai J (2014) Circulating MicroRNA profiles altered in mice after 28 days exposure to perfluorooctanoic acid. Toxicol Lett 224(1):24–31
    • (2014) Toxicol Lett , vol.224 , Issue.1 , pp. 24-31
    • Yan, S.1    Wang, J.2    Zhang, W.3    Dai, J.4
  • 35
    • 12444256363 scopus 로고    scopus 로고
    • Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling
    • COI: 1:CAS:528:DC%2BD3sXlt1Kruro%3D, PID: 12730331
    • Yoshikawa T, Ide T, Shimano H et al (2003) Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling. Mol Endocrinol 17(7):1240–1254
    • (2003) Mol Endocrinol , vol.17 , Issue.7 , pp. 1240-1254
    • Yoshikawa, T.1    Ide, T.2    Shimano, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.