High Fat Diet Feeding Exaggerates Perfluorooctanoic Acid-Induced Liver Injury in Mice via Modulating Multiple Metabolic Pathways

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Tan, Xiaobing ^a   Xie, Guoxiang ^a   Sun, Xiuhua ^a   Li, Qiong ^a   Zhong, Wei ^a   Qiao, Peter ^b   Sun, Xinguo ^a   Jia, Wei ^a   Zhou, Zhanxiang ^a  

^a UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CXCL1 CHEMOKINE; FAT DROPLET; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1BETA; LONG CHAIN FATTY ACID; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; PERFLUOROOCTANOIC ACID; RANTES; TUMOR NECROSIS FACTOR ALPHA; FATTY ACID; FLUOROCARBON; OCTANOIC ACID DERIVATIVE; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL INFILTRATION; CONTROLLED STUDY; DRUG METABOLISM; FATTY ACID METABOLISM; GENE EXPRESSION; GLUCOSE METABOLISM; HEPATITIS; LIPID DIET; LIPID STORAGE; LIVER DISEASE; LIVER HYPERTROPHY; LIVER METABOLISM; LIVER NECROSIS; LIVER TOXICITY; LIVER WEIGHT; MALE; METABOLIC DISORDER; METABOLOMICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; UPREGULATION; WEIGHT REDUCTION; ANIMAL; BLOOD; BODY WEIGHT; C57BL MOUSE; CHEMICALLY INDUCED; COMPLICATION; DRUG EFFECTS; FATTY LIVER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INFLAMMATION; LIPID METABOLISM; LIVER; LIVER CELL; METABOLISM; NECROSIS; ORGAN SIZE; PATHOLOGY; TOXICITY; WHITE ADIPOSE TISSUE;

MUS;

ADIPOSE TISSUE, WHITE; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BODY WEIGHT; CAPRYLATES; DIET, HIGH-FAT; FATTY ACIDS; FATTY LIVER; FLUOROCARBONS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEPATOCYTES; INFLAMMATION; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; NECROSIS; ORGAN SIZE; TRIGLYCERIDES;

EID: 84876551716     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061409     Document Type: Article

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