-
1
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
-
Escudier B, Pluzanska A, Koralewski P, et al. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007;370:2103-11
-
(2007)
Lancet
, vol.370
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
-
2
-
-
56749161699
-
Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206
-
Rini BI, Halabi S, Rosenberg JE, et al. Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206. J Clin Oncol 2008;26: 5422-8
-
(2008)
J Clin Oncol
, vol.26
, pp. 5422-5428
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
-
3
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Eisen T, Stadler WM, et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007;356:125-34
-
(2007)
N Engl J Med
, vol.356
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
-
4
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007;356:115-24
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
5
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg CN, Davis ID, Mardiak J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010;28: 1061-8
-
(2010)
J Clin Oncol
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
-
6
-
-
82755183572
-
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
-
Rini BI, Escudier B, Tomczak P, et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet 2011;378:1931-9
-
(2011)
Lancet
, vol.378
, pp. 1931-1939
-
-
Rini, B.I.1
Escudier, B.2
Tomczak, P.3
-
7
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
Hudes G, Carducci M, Tomczak P, et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007;356:2271-81
-
(2007)
N Engl J Med
, vol.356
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
-
8
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
-
Motzer RJ, Escudier B, Oudard S, et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet 2008;372:449-56
-
(2008)
Lancet
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
10
-
-
84905403670
-
Molecular genetics of clear-cell renal cell carcinoma
-
Brugarolas J. Molecular genetics of clear-cell renal cell carcinoma. J Clin Oncol 2014;32: 1968-76
-
(2014)
J Clin Oncol
, vol.32
, pp. 1968-1976
-
-
Brugarolas, J.1
-
11
-
-
40249100323
-
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
-
Young AP, Schlisio S, Minamishima YA, et al. VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400. Nat Cell Biol 2008;10:361-9
-
(2008)
Nat Cell Biol
, vol.10
, pp. 361-369
-
-
Young, A.P.1
Schlisio, S.2
Minamishima, Y.A.3
-
12
-
-
84862988411
-
BAP1 loss defines a new class of renal cell carcinoma
-
Pena-Llopis S, Vega-Rubin-de-Celis S, Liao A, et al. BAP1 loss defines a new class of renal cell carcinoma. Nat Genet 2012;44: 751-9
-
(2012)
Nat Genet
, vol.44
, pp. 751-759
-
-
Pena-Llopis, S.1
Vega-Rubin-De-Celis, S.2
Liao, A.3
-
13
-
-
84879466482
-
Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: A report by MSKCC and the KIRC TCGA research network
-
Hakimi AA, Ostrovnaya I, Reva B, et al. Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research network. Clin Cancer Res 2013;19:3259-67
-
(2013)
Clin Cancer Res
, vol.19
, pp. 3259-3267
-
-
Hakimi, A.A.1
Ostrovnaya, I.2
Reva, B.3
-
14
-
-
84873081430
-
Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: A retrospective analysis with independent validation
-
Kapur P, Pena-Llopis S, Christie A, et al. Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation. Lancet Oncol 2013;14:159-67
-
(2013)
Lancet Oncol
, vol.14
, pp. 159-167
-
-
Kapur, P.1
Pena-Llopis, S.2
Christie, A.3
-
15
-
-
58249095937
-
BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity
-
Nishikawa H, Wu W, Koike A, et al. BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity. Cancer Res 2009;69:111-19
-
(2009)
Cancer Res
, vol.69
, pp. 111-119
-
-
Nishikawa, H.1
Wu, W.2
Koike, A.3
-
16
-
-
0037122004
-
Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
-
Mallery DL, Vandenberg CJ, Hiom K. Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains. EMBO J 2002;21:6755-62
-
(2002)
EMBO J
, vol.21
, pp. 6755-6762
-
-
Mallery, D.L.1
Vandenberg, C.J.2
Hiom, K.3
-
17
-
-
84915822435
-
Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis
-
Wang SS, Gu YF, Wolff N, et al. Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis. Proc Natl Acad Sci USA 2014;111:16538-43
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 16538-16543
-
-
Wang, S.S.1
Gu, Y.F.2
Wolff, N.3
-
18
-
-
78649700287
-
Frequent mutation of BAP1 in metastasizing uveal melanomas
-
Harbour JW, Onken MD, Roberson ED, et al. Frequent mutation of BAP1 in metastasizing uveal melanomas. Science 2010;330:1410-13
-
(2010)
Science
, vol.330
, pp. 1410-1413
-
-
Harbour, J.W.1
Onken, M.D.2
Roberson, E.D.3
-
19
-
-
84856023489
-
Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma
-
Landreville S, Agapova OA, Matatall KA, et al. Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma. Clin Cancer Res 2012;18: 408-16
-
(2012)
Clin Cancer Res
, vol.18
, pp. 408-416
-
-
Landreville, S.1
Agapova, O.A.2
Matatall, K.A.3
-
20
-
-
84921629564
-
BAP1 regulates cell cycle progression through E2F1 target genes and mediates transcriptional silencing via H2A monoubiquitination in uveal melanoma cells
-
Pan H, Jia R, Zhang L, et al. BAP1 regulates cell cycle progression through E2F1 target genes and mediates transcriptional silencing via H2A monoubiquitination in uveal melanoma cells. Int J Biochem Cell Biol 2015;60:176-84
-
(2015)
Int J Biochem Cell Biol
, vol.60
, pp. 176-184
-
-
Pan, H.1
Jia, R.2
Zhang, L.3
-
21
-
-
84925442599
-
BAP1 Has a Survival Role in Cutaneous Melanoma
-
Kumar R, Taylor M, Miao B, et al. BAP1 Has a Survival Role in Cutaneous Melanoma. J Invest Dermatol 2015;135: 1089-97
-
(2015)
J Invest Dermatol
, vol.135
, pp. 1089-1097
-
-
Kumar, R.1
Taylor, M.2
Miao, B.3
-
22
-
-
79959694149
-
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma
-
Bott M, Brevet M, Taylor BS, et al. The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma. Nat Genet 2011;43:668-72
-
(2011)
Nat Genet
, vol.43
, pp. 668-672
-
-
Bott, M.1
Brevet, M.2
Taylor, B.S.3
-
23
-
-
84928486573
-
Molecular pathways in renal cell carcinoma: Recent advances in genetics and molecular biology
-
Su D, Singer EA, Srinivasan R. Molecular pathways in renal cell carcinoma: recent advances in genetics and molecular biology. Curr Opin Oncol 2015;27:217-23
-
(2015)
Curr Opin Oncol
, vol.27
, pp. 217-223
-
-
Su, D.1
Singer, E.A.2
Srinivasan, R.3
-
24
-
-
40949111565
-
BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer
-
Xia W, Nagase S, Montia AG, et al. BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer. Cancer Res 2008;68:1667-74
-
(2008)
Cancer Res
, vol.68
, pp. 1667-1674
-
-
Xia, W.1
Nagase, S.2
Montia, A.G.3
-
25
-
-
77956271441
-
Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence
-
Burrows AE, Smogorzewska A, Elledge SJ. Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence. Proc Natl Acad Sci USA 2010;107:14280-5
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14280-14285
-
-
Burrows, A.E.1
Smogorzewska, A.2
Elledge, S.J.3
-
26
-
-
84919451538
-
Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin
-
Kakarougkas A, Ismail A, Chambers AL, et al. Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin. Mol Cell 2014;55:723-32
-
(2014)
Mol Cell
, vol.55
, pp. 723-732
-
-
Kakarougkas, A.1
Ismail, A.2
Chambers, A.L.3
-
27
-
-
84897050302
-
BAF180 promotes cohesion and prevents genome instability and aneuploidy
-
Brownlee PM, Chambers AL, Cloney R, et al. BAF180 promotes cohesion and prevents genome instability and aneuploidy. Cell Rep 2014;6:973-81
-
(2014)
Cell Rep
, vol.6
, pp. 973-981
-
-
Brownlee, P.M.1
Chambers, A.L.2
Cloney, R.3
-
28
-
-
79251635938
-
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
-
Varela I, Tarpey P, Raine K, et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 2011;469:539-42
-
(2011)
Nature
, vol.469
, pp. 539-542
-
-
Varela, I.1
Tarpey, P.2
Raine, K.3
-
29
-
-
84857129204
-
Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer
-
Shain AH, Giacomini CP, Matsukuma K, et al. Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer. Proc Natl Acad Sci USA 2012;109:E252-9
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. E252-E259
-
-
Shain, A.H.1
Giacomini, C.P.2
Matsukuma, K.3
-
30
-
-
70049111751
-
The mRNA expression of SETD2 in human breast cancer: Correlation with clinico-pathological parameters
-
Al Sarakbi W, Sasi W, Jiang WG, et al. The mRNA expression of SETD2 in human breast cancer: correlation with clinico-pathological parameters. BMC Cancer 2009;9:290
-
(2009)
BMC Cancer
, vol.9
, pp. 290
-
-
Al Sarakbi, W.1
Sasi, W.2
Jiang, W.G.3
-
31
-
-
84862907593
-
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
-
Zhang J, Ding L, Holmfeldt L, et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 2012;481: 157-63
-
(2012)
Nature
, vol.481
, pp. 157-163
-
-
Zhang, J.1
Ding, L.2
Holmfeldt, L.3
-
32
-
-
84879890360
-
Comprehensive molecular characterization of clear cell renal cell carcinoma
-
Creighton CJ, Morgan M, Gunaratne PH, et al. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 2013;499:43-9
-
(2013)
Nature
, vol.499
, pp. 43-49
-
-
Creighton, C.J.1
Morgan, M.2
Gunaratne, P.H.3
-
33
-
-
84893664978
-
Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects
-
Simon JM, Hacker KE, Singh D, et al. Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects. Genome Res 2014;24:241-50
-
(2014)
Genome Res
, vol.24
, pp. 241-250
-
-
Simon, J.M.1
Hacker, K.E.2
Singh, D.3
-
34
-
-
84876943255
-
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSalpha
-
Li F, Mao G, Tong D, et al. The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSalpha. Cell 2013;153: 590-600
-
(2013)
Cell
, vol.153
, pp. 590-600
-
-
Li, F.1
Mao, G.2
Tong, D.3
-
35
-
-
84899849011
-
SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint
-
Carvalho S, Vitor AC, Sridhara SC, et al. SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint. Elife 2014;3: e02482
-
(2014)
Elife
, vol.3
, pp. e02482
-
-
Carvalho, S.1
Vitor, A.C.2
Sridhara, S.C.3
-
36
-
-
84903451450
-
SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability
-
Pfister SX, Ahrabi S, Zalmas LP, et al. SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability. Cell Rep 2014;7:2006-18
-
(2014)
Cell Rep
, vol.7
, pp. 2006-2018
-
-
Pfister, S.X.1
Ahrabi, S.2
Zalmas, L.P.3
-
37
-
-
84861217853
-
Evolutionary constraint helps unmask a splicing regulatory region in BRCA1 exon 11
-
Raponi M, Douglas AG, Tammaro C, et al. Evolutionary constraint helps unmask a splicing regulatory region in BRCA1 exon 11. PLoS One 2012;7:e37255
-
(2012)
PLoS One
, vol.7
, pp. e37255
-
-
Raponi, M.1
Douglas, A.G.2
Tammaro, C.3
-
38
-
-
84857687714
-
SpliceAid 2: A database of human splicing factors expression data and RNA target motifs
-
Piva F, Giulietti M, Burini AB, Principato G. SpliceAid 2: a database of human splicing factors expression data and RNA target motifs. Hum Mutat 2012;33: 81-5
-
(2012)
Hum Mutat
, vol.33
, pp. 81-85
-
-
Piva, F.1
Giulietti, M.2
Burini, A.B.3
Principato, G.4
-
39
-
-
84876037266
-
Clinical and pathologic impact of select chromatin-modulating tumor suppressors in clear cell renal cell carcinoma
-
Hakimi AA, Chen YB, Wren J, et al. Clinical and pathologic impact of select chromatin-modulating tumor suppressors in clear cell renal cell carcinoma. Eur Urol 2013;63:848-54
-
(2013)
Eur Urol
, vol.63
, pp. 848-854
-
-
Hakimi, A.A.1
Chen, Y.B.2
Wren, J.3
-
40
-
-
84869487977
-
Loss of PBRM1 expression is associated with renal cell carcinoma progression
-
Pawlowski R, Muhl SM, Sulser T, et al. Loss of PBRM1 expression is associated with renal cell carcinoma progression. Int J Cancer 2013;132:E11-17
-
(2013)
Int J Cancer
, vol.132
, pp. E11-17
-
-
Pawlowski, R.1
Muhl, S.M.2
Sulser, T.3
-
41
-
-
84922590453
-
Loss of PBRM1 and BAP1 expression is less common in non-clear cell renal cell carcinoma than in clear cell renal cell carcinoma
-
Ho TH, Kapur P, Joseph RW, et al. Loss of PBRM1 and BAP1 expression is less common in non-clear cell renal cell carcinoma than in clear cell renal cell carcinoma. Urol Oncol 2015;33:23 e9-14
-
(2015)
Urol Oncol
, vol.33
, pp. 23e914
-
-
Ho, T.H.1
Kapur, P.2
Joseph, R.W.3
-
42
-
-
85028129789
-
Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes
-
Durinck S, Stawiski EW, Pavia-Jimenez A, et al. Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes. Nat Genet 2015;47: 13-21
-
(2015)
Nat Genet
, vol.47
, pp. 13-21
-
-
Durinck, S.1
Stawiski, E.W.2
Pavia-Jimenez, A.3
-
43
-
-
84895876130
-
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
-
Gerlinger M, Horswell S, Larkin J, et al. Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing. Nat Genet 2014;46:225-33
-
(2014)
Nat Genet
, vol.46
, pp. 225-233
-
-
Gerlinger, M.1
Horswell, S.2
Larkin, J.3
-
44
-
-
84880898004
-
Cooperation and antagonism among cancer genes: The renal cancer paradigm
-
Pena-Llopis S, Christie A, Xie XJ, Brugarolas J. Cooperation and antagonism among cancer genes: the renal cancer paradigm. Cancer Res 2013;73:4173-9
-
(2013)
Cancer Res
, vol.73
, pp. 4173-4179
-
-
Pena-Llopis, S.1
Christie, A.2
Xie, X.J.3
Brugarolas, J.4
-
45
-
-
84885735554
-
Mutational landscape and significance across 12 major cancer types
-
Kandoth C, McLellan MD, Vandin F, et al. Mutational landscape and significance across 12 major cancer types. Nature 2013;502: 333-9
-
(2013)
Nature
, vol.502
, pp. 333-339
-
-
Kandoth, C.1
McLellan, M.D.2
Vandin, F.3
-
46
-
-
84878846119
-
Germline BAP1 mutations predispose to renal cell carcinomas
-
Popova T, Hebert L, Jacquemin V, et al. Germline BAP1 mutations predispose to renal cell carcinomas. Am J Hum Genet 2013;92:974-80
-
(2013)
Am J Hum Genet
, vol.92
, pp. 974-980
-
-
Popova, T.1
Hebert, L.2
Jacquemin, V.3
-
47
-
-
84884497841
-
A novel germline mutation in BAP1 predisposes to familial clear-cell renal cell carcinoma
-
Farley MN, Schmidt LS, Mester JL, et al. A novel germline mutation in BAP1 predisposes to familial clear-cell renal cell carcinoma. Mol Cancer Res 2013;11: 1061-71
-
(2013)
Mol Cancer Res
, vol.11
, pp. 1061-1071
-
-
Farley, M.N.1
Schmidt, L.S.2
Mester, J.L.3
-
48
-
-
84856023369
-
Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers
-
Abdel-Rahman MH, Pilarski R, Cebulla CM, et al. Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers. J Med Genet 2011;48:856-9
-
(2011)
J Med Genet
, vol.48
, pp. 856-859
-
-
Abdel-Rahman, M.H.1
Pilarski, R.2
Cebulla, C.M.3
-
49
-
-
80053385701
-
Germline BAP1 mutations predispose to malignant mesothelioma
-
Testa JR, Cheung M, Pei J, et al. Germline BAP1 mutations predispose to malignant mesothelioma. Nat Genet 2011;43:1022-5
-
(2011)
Nat Genet
, vol.43
, pp. 1022-1025
-
-
Testa, J.R.1
Cheung, M.2
Pei, J.3
-
50
-
-
84860142904
-
Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families
-
Njauw CN, Kim I, Piris A, et al. Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families. PLoS ONE 2012;7:e35295
-
(2012)
PLoS ONE
, vol.7
, pp. e35295
-
-
Njauw, C.N.1
Kim, I.2
Piris, A.3
-
51
-
-
84874372159
-
Prevalence of germline BAP1 mutation in a population-based sample of uveal melanoma cases
-
Aoude LG, Vajdic CM, Kricker A, et al. Prevalence of germline BAP1 mutation in a population-based sample of uveal melanoma cases. Pigment Cell Melanoma Res 2013;26: 278-9
-
(2013)
Pigment Cell Melanoma Res
, vol.26
, pp. 278-279
-
-
Aoude, L.G.1
Vajdic, C.M.2
Kricker, A.3
-
52
-
-
84922520667
-
Germline BAP1 mutations predispose also to multiple basal cell carcinomas
-
de la Fouchardiere A, Cabaret O, Savin L, et al. Germline BAP1 mutations predispose also to multiple basal cell carcinomas. Clin Genet 2014
-
(2014)
Clin Genet
-
-
De La Fouchardiere, A.1
Cabaret, O.2
Savin, L.3
-
53
-
-
84922337420
-
Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high-risk area
-
Betti M, Casalone E, Ferrante D, et al. Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high-risk area. Genes Chromosomes Cancer 2015;54:51-62
-
(2015)
Genes Chromosomes Cancer
, vol.54
, pp. 51-62
-
-
Betti, M.1
Casalone, E.2
Ferrante, D.3
-
55
-
-
84877343113
-
Aberrant promoter hypermethylation of PBRM1, BAP1, SETD2, KDM6A and other chromatin-modifying genes is absent or rare in clear cell RCC
-
Ibragimova I, Maradeo ME, Dulaimi E, Cairns P. Aberrant promoter hypermethylation of PBRM1, BAP1, SETD2, KDM6A and other chromatin-modifying genes is absent or rare in clear cell RCC. Epigenetics 2013;8: 486-93
-
(2013)
Epigenetics
, vol.8
, pp. 486-493
-
-
Ibragimova, I.1
Maradeo, M.E.2
Dulaimi, E.3
Cairns, P.4
-
56
-
-
84921754876
-
Alterations in chromatin accessibility and DNA methylation in clear cell renal cell carcinoma
-
Buck MJ, Raaijmakers LM, Ramakrishnan S, et al. Alterations in chromatin accessibility and DNA methylation in clear cell renal cell carcinoma. Oncogene 2014;33:4961-5
-
(2014)
Oncogene
, vol.33
, pp. 4961-4965
-
-
Buck, M.J.1
Raaijmakers, L.M.2
Ramakrishnan, S.3
-
57
-
-
84899421896
-
Loss of BAP1 protein expression is an independent marker of poor prognosis in patients with low-risk clear cell renal cell carcinoma
-
Joseph RW, Kapur P, Serie DJ, et al. Loss of BAP1 protein expression is an independent marker of poor prognosis in patients with low-risk clear cell renal cell carcinoma. Cancer 2014;120:1059-67
-
(2014)
Cancer
, vol.120
, pp. 1059-1067
-
-
Joseph, R.W.1
Kapur, P.2
Serie, D.J.3
-
58
-
-
84893482700
-
Radiogenomics of clear cell renal cell carcinoma: Associations between CT imaging features and mutations
-
Karlo CA, Di Paolo PL, Chaim J, et al. Radiogenomics of clear cell renal cell carcinoma: associations between CT imaging features and mutations. Radiology 2014;270:464-71
-
(2014)
Radiology
, vol.270
, pp. 464-471
-
-
Karlo, C.A.1
Di Paolo, P.L.2
Chaim, J.3
-
59
-
-
84888640837
-
BAP1 is phosphorylated at serine 592 in S-phase following DNA damage
-
Eletr ZM, Yin L, Wilkinson KD. BAP1 is phosphorylated at serine 592 in S-phase following DNA damage. FEBS Lett 2013;587:3906-11
-
(2013)
FEBS Lett
, vol.587
, pp. 3906-3911
-
-
Eletr, Z.M.1
Yin, L.2
Wilkinson, K.D.3
-
60
-
-
84891912266
-
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
-
Yu H, Pak H, Hammond-Martel I, et al. Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair. Proc Natl Acad Sci USA 2014;111: 285-90
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 285-290
-
-
Yu, H.1
Pak, H.2
Hammond-Martel, I.3
-
61
-
-
79960197509
-
A phase II trial of panobinostat, a histone deacetylase inhibitor, in the treatment of patients with refractory metastatic renal cell carcinoma
-
Hainsworth JD, Infante JR, Spigel DR, et al. A phase II trial of panobinostat, a histone deacetylase inhibitor, in the treatment of patients with refractory metastatic renal cell carcinoma. Cancer Invest 2011;29:451-5
-
(2011)
Cancer Invest
, vol.29
, pp. 451-455
-
-
Hainsworth, J.D.1
Infante, J.R.2
Spigel, D.R.3
-
62
-
-
33749049594
-
A phase II study of depsipeptide in refractory metastatic renal cell cancer
-
Stadler WM, Margolin K, Ferber S, et al. A phase II study of depsipeptide in refractory metastatic renal cell cancer. Clin Genitourin Cancer 2006;5:57-60
-
(2006)
Clin Genitourin Cancer
, vol.5
, pp. 57-60
-
-
Stadler, W.M.1
Margolin, K.2
Ferber, S.3
-
63
-
-
84940493308
-
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, Vorinostat in Treating Patients With Kidney Cancer
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, Vorinostat in Treating Patients With Kidney Cancer. Available from: https://clinicaltrials.gov/ct2/show/NCT00278395
-
-
-
-
64
-
-
84940491868
-
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma. Available from: https://clinicaltrials.gov/ct2/show/NCT00020579
-
-
-
-
65
-
-
84940512646
-
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, Study of Oral PXD101 in Patients With Advanced Solid Tumors or Lymphoma
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, Study of Oral PXD101 in Patients With Advanced Solid Tumors or Lymphoma. Available from: https://clinicaltrials.gov/ct2/show/NCT00413075
-
-
-
-
66
-
-
84940474418
-
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, Entinostat in Combination With Aldesleukin in Treating Patients With Metastatic Kidney Cancer
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, Entinostat in Combination With Aldesleukin in Treating Patients With Metastatic Kidney Cancer. Available from: https://clinicaltrials.gov/ct2/show/NCT01038778
-
-
-
-
67
-
-
84940498091
-
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, Trial of Olaparib in Combination With AZD5363 (ComPAKT)
-
Clinical trials.gov, A service of the U.S. National Institutes of Health, Trial of Olaparib in Combination With AZD5363 (ComPAKT). Available from: https://clinicaltrials.gov/ct2/show/NCT02338622
-
-
-
-
68
-
-
84655176646
-
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma
-
Guo G, Gui Y, Gao S, et al. Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma. Nat Genet 2012;44:17-19
-
(2012)
Nat Genet
, vol.44
, pp. 17-19
-
-
Guo, G.1
Gui, Y.2
Gao, S.3
-
69
-
-
84880967722
-
Integrated molecular analysis of clear-cell renal cell carcinoma
-
Sato Y, Yoshizato T, Shiraishi Y, et al. Integrated molecular analysis of clear-cell renal cell carcinoma. Nat Genet 2013;45: 860-7
-
(2013)
Nat Genet
, vol.45
, pp. 860-867
-
-
Sato, Y.1
Yoshizato, T.2
Shiraishi, Y.3
|