Evolutionary constraint helps unmask a splicing regulatory region in brca1 exon 11

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Raponi, Michela ^a   Douglas, Andrew G L ^a,b   Tammaro, Claudia ^a   Wilson, David I ^a   Baralle, Diana ^a,b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; TRANSACTIVATOR PROTEIN;

ALTERNATIVE RNA SPLICING; ARTICLE; CARCINOGENESIS; CODON; CONTROLLED STUDY; EXON; GENE ACTIVITY; GENE DELETION; GENE FUNCTION; GENETIC IDENTIFICATION; GENETIC REGULATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MOLECULAR EVOLUTION; ONCOGENE; RNA EXTRACTION; RNA SEQUENCE; BREAST TUMOR; EVOLUTION; FEMALE; GENETICS; MUTATION; PHYSIOLOGY; REGULATORY SEQUENCE; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

ALTERNATIVE SPLICING; BIOLOGICAL EVOLUTION; BREAST NEOPLASMS; CELL LINE, TUMOR; CODON; EXONS; FEMALE; GENE DELETION; GENES, BRCA1; HUMANS; MUTATION; REGULATORY SEQUENCES, NUCLEIC ACID; TRANS-ACTIVATORS;

EID: 84861217853     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037255     Document Type: Article

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