-
1
-
-
77952263737
-
The genetic basis of kidney cancer: A metabolic disease
-
PMID:20448661
-
Linehan WM, Srinivasan R, Schmidt LS. The genetic basis of kidney cancer: a metabolic disease. Nat Rev Urol 2010; 7:277-85; PMID:20448661; http://dx.doi. org/10.1038/nrurol.2010.47.
-
(2010)
Nat Rev Urol
, vol.7
, pp. 277-285
-
-
Linehan, W.M.1
Srinivasan, R.2
Schmidt, L.S.3
-
2
-
-
2342583527
-
Searching for the hereditary causes of renal-cell carcinoma
-
PMID:15122209
-
Pavlovich CP, Schmidt LS. Searching for the hereditary causes of renal-cell carcinoma. Nat Rev Cancer 2004; 4:381-93; PMID:15122209; http://dx.doi. org/10.1038/nrc1364.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 381-393
-
-
Pavlovich, C.P.1
Schmidt, L.S.2
-
3
-
-
75149188170
-
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
-
PMID:20054297
-
Dalgliesh GL, Furge K, Greenman C, Chen L, Bignell G, Butler A, et al. Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Nature 2010; 463:360-3; PMID:20054297; http://dx.doi.org/10.1038/nature08672.
-
(2010)
Nature
, vol.463
, pp. 360-363
-
-
Dalgliesh, G.L.1
Furge, K.2
Greenman, C.3
Chen, L.4
Bignell, G.5
Butler, A.6
-
4
-
-
84655176646
-
Frequent mutations of genes encoding ubiquitinmediated proteolysis pathway components in clear cell renal cell carcinoma
-
PMID:22138691
-
Guo G, Gui Y, Gao S, Tang A, Hu X, Huang Y, et al. Frequent mutations of genes encoding ubiquitinmediated proteolysis pathway components in clear cell renal cell carcinoma. Nat Genet 2012; 44:17-9; PMID:22138691; http://dx.doi.org/10.1038/ng.1014.
-
(2012)
Nat Genet
, vol.44
, pp. 17-19
-
-
Guo, G.1
Gui, Y.2
Gao, S.3
Tang, A.4
Hu, X.5
Huang, Y.6
-
5
-
-
84862988411
-
BAP1 loss defines a new class of renal cell carcinoma
-
PMID:22683710
-
Peña-Llopis S, Vega-Rubín-de-Celis S, Liao A, Leng N, Pavía-Jiménez A, Wang S, et al. BAP1 loss defines a new class of renal cell carcinoma. Nat Genet 2012; 44:751-9; PMID:22683710; http://dx.doi.org/10.1038/ng.2323.
-
(2012)
Nat Genet
, vol.44
, pp. 751-759
-
-
Peña-Llopis, S.1
Vega-Rubín-de-Celis, S.2
Liao, A.3
Leng, N.4
Pavía-Jiménez, A.5
Wang, S.6
-
6
-
-
79251635938
-
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
-
PMID:21248752
-
Varela I, Tarpey P, Raine K, Huang D, Ong CK, Stephens P, et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 2011; 469:539-42; PMID:21248752; http://dx.doi.org/10.1038/nature09639.
-
(2011)
Nature
, vol.469
, pp. 539-542
-
-
Varela, I.1
Tarpey, P.2
Raine, K.3
Huang, D.4
Ong, C.K.5
Stephens, P.6
-
7
-
-
84861898073
-
Targeted exome sequencing in clear cell renal cell carcinoma tumors suggests aberrant chromatin regulation as a crucial step in ccRCC development
-
PMID:22461374
-
Duns G, Hofstra RM, Sietzema JG, Hollema H, van Duivenbode I, Kuik A, et al. Targeted exome sequencing in clear cell renal cell carcinoma tumors suggests aberrant chromatin regulation as a crucial step in ccRCC development. Hum Mutat 2012; 33:1059-62; http://dx.doi.org/10.1002/humu.22090; PMID:22461374.
-
(2012)
Hum Mutat
, vol.33
, pp. 1059-1062
-
-
Duns, G.1
Hofstra, R.M.2
Sietzema, J.G.3
Hollema, H.4
van Duivenbode, I.5
Kuik, A.6
-
8
-
-
77957731999
-
Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
-
PMID:20826764
-
Jones S, Wang TL, Shih IeM, Mao TL, Nakayama K, Roden R, et al. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science 2010; 330:228-31; PMID:20826764; http://dx.doi.org/10.1126/science.1196333.
-
(2010)
Science
, vol.330
, pp. 228-231
-
-
Jones, S.1
Wang, T.L.2
Shih, I.M.3
Mao, T.L.4
Nakayama, K.5
Roden, R.6
-
9
-
-
77957946398
-
ARID1A mutations in endometriosis-associated ovarian carcinomas
-
PMID:20942669
-
Wiegand KC, Shah SP, Al-Agha OM, Zhao Y, Tse K, Zeng T, et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med 2010; 363:1532-43; http://dx.doi.org/10.1056/NEJMoa1008433; PMID:20942669.
-
(2010)
N Engl J Med
, vol.363
, pp. 1532-1543
-
-
Wiegand, K.C.1
Shah, S.P.2
Al-Agha, O.M.3
Zhao, Y.4
Tse, K.5
Zeng, T.6
-
10
-
-
80052266351
-
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
-
PMID:21822268
-
Gui Y, Guo G, Huang Y, Hu X, Tang A, Gao S, et al. Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat Genet 2011; 43:875-8; PMID:21822268; http://dx.doi. org/10.1038/ng.907.
-
(2011)
Nat Genet
, vol.43
, pp. 875-878
-
-
Gui, Y.1
Guo, G.2
Huang, Y.3
Hu, X.4
Tang, A.5
Gao, S.6
-
11
-
-
84857467474
-
Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types
-
PMID:22009941
-
Jones S, Li M, Parsons DW, Zhang X, Wesseling J, Kristel P, et al. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum Mutat 2012; 33:100-3; http://dx.doi. org/10.1002/humu.21633; PMID:22009941.
-
(2012)
Hum Mutat
, vol.33
, pp. 100-103
-
-
Jones, S.1
Li, M.2
Parsons, D.W.3
Zhang, X.4
Wesseling, J.5
Kristel, P.6
-
12
-
-
67349203626
-
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
-
PMID:19330029
-
van Haaften G, Dalgliesh GL, Davies H, Chen L, Bignell G, Greenman C, et al. Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. Nat Genet 2009; 41:521-3; PMID:19330029; http://dx.doi.org/10.1038/ng.349.
-
(2009)
Nat Genet
, vol.41
, pp. 521-523
-
-
van Haaften, G.1
Dalgliesh, G.L.2
Davies, H.3
Chen, L.4
Bignell, G.5
Greenman, C.6
-
13
-
-
84864419974
-
Dissecting the genomic complexity underlying medulloblastoma
-
PMID:22832583
-
Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, et al. Dissecting the genomic complexity underlying medulloblastoma. Nature 2012; 488:100-5; PMID:22832583; http://dx.doi.org/10.1038/nature11284.
-
(2012)
Nature
, vol.488
, pp. 100-105
-
-
Jones, D.T.1
Jäger, N.2
Kool, M.3
Zichner, T.4
Hutter, B.5
Sultan, M.6
-
14
-
-
84857942952
-
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
-
PMID:22343534
-
Lohr JG, Stojanov P, Lawrence MS, Auclair D, Chapuy B, Sougnez C, et al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc Natl Acad Sci U S A 2012; 109:3879-84; PMID:22343534; http://dx.doi.org/10.1073/pnas.1121343109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 3879-3884
-
-
Lohr, J.G.1
Stojanov, P.2
Lawrence, M.S.3
Auclair, D.4
Chapuy, B.5
Sougnez, C.6
-
15
-
-
80052029516
-
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
-
PMID:21796119
-
Morin RD, Mendez-Lago M, Mungall AJ, Goya R, Mungall KL, Corbett RD, et al. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature 2011; 476:298-303; PMID:21796119; http://dx.doi.org/10.1038/nature10351.
-
(2011)
Nature
, vol.476
, pp. 298-303
-
-
Morin, R.D.1
Mendez-Lago, M.2
Mungall, A.J.3
Goya, R.4
Mungall, K.L.5
Corbett, R.D.6
-
16
-
-
84864492215
-
Medulloblastoma exome sequencing uncovers subtypespecific somatic mutations
-
PMID:22820256
-
Pugh TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D, Bochicchio J, et al. Medulloblastoma exome sequencing uncovers subtypespecific somatic mutations. Nature 2012; 488:106-10; PMID:22820256; http://dx.doi.org/10.1038/nature11329.
-
(2012)
Nature
, vol.488
, pp. 106-110
-
-
Pugh, T.J.1
Weeraratne, S.D.2
Archer, T.C.3
Pomeranz Krummel, D.A.4
Auclair, D.5
Bochicchio, J.6
-
17
-
-
78649700287
-
Frequent mutation of BAP1 in metastasizing uveal melanomas
-
PMID:21051595
-
Harbour JW, Onken MD, Roberson ED, Duan S, Cao L, Worley LA, et al. Frequent mutation of BAP1 in metastasizing uveal melanomas. Science 2010; 330:1410-3; PMID:21051595; http://dx.doi. org/10.1126/science.1194472.
-
(2010)
Science
, vol.330
, pp. 1410-1413
-
-
Harbour, J.W.1
Onken, M.D.2
Roberson, E.D.3
Duan, S.4
Cao, L.5
Worley, L.A.6
-
18
-
-
79959694149
-
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma
-
PMID:21642991
-
Bott M, Brevet M, Taylor BS, Shimizu S, Ito T, Wang L, et al. The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma. Nat Genet 2011; 43:668-72; PMID:21642991; http://dx.doi. org/10.1038/ng.855.
-
(2011)
Nat Genet
, vol.43
, pp. 668-672
-
-
Bott, M.1
Brevet, M.2
Taylor, B.S.3
Shimizu, S.4
Ito, T.5
Wang, L.6
-
19
-
-
84866456618
-
Cancer. Emerging anatomy of the BAP1 tumor suppressor system
-
PMID:22997315
-
White AE, Harper JW. Cancer. Emerging anatomy of the BAP1 tumor suppressor system. Science 2012; 337:1463-4; PMID:22997315; http://dx.doi. org/10.1126/science.1228463.
-
(2012)
Science
, vol.337
, pp. 1463-1464
-
-
White, A.E.1
Harper, J.W.2
-
20
-
-
40849139208
-
Epigenetics in cancer
-
PMID:18337604
-
Esteller M. Epigenetics in cancer. N Engl J Med 2008; 358:1148-59; PMID:18337604; http://dx.doi. org/10.1056/NEJMra072067.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
21
-
-
33847065486
-
The epigenomics of cancer
-
PMID:17320506
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128:683-92; PMID:17320506; http://dx.doi. org/10.1016/j.cell.2007.01.029.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
22
-
-
38949093560
-
Genetic and epigenetic alterations in the von hippel-lindau gene: The influence on renal cancer prognosis
-
PMID:18245539
-
Smits KM, Schouten LJ, van Dijk BA, Hulsbergen-van de Kaa CA, Wouters KA, Oosterwijk E, et al. Genetic and epigenetic alterations in the von hippel-lindau gene: the influence on renal cancer prognosis. Clin Cancer Res 2008; 14:782-7; PMID:18245539; http://dx.doi.org/10.1158/1078-0432.CCR-07-1753.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 782-787
-
-
Smits, K.M.1
Schouten, L.J.2
van Dijk, B.A.3
Hulsbergen-van de Kaa, C.A.4
Wouters, K.A.5
Oosterwijk, E.6
-
23
-
-
3042538398
-
Promoter hypermethylation profile of kidney cancer
-
PMID:15217927
-
Dulaimi E, Ibanez de Caceres I, Uzzo RG, Al-Saleem T, Greenberg RE, Polascik TJ, et al. Promoter hypermethylation profile of kidney cancer. Clin Cancer Res 2004; 10:3972-9; PMID:15217927; http://dx.doi. org/10.1158/1078-0432.CCR-04-0175.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3972-3979
-
-
Dulaimi, E.1
Ibanez de Caceres, I.2
Uzzo, R.G.3
Al-Saleem, T.4
Greenberg, R.E.5
Polascik, T.J.6
-
24
-
-
0028072991
-
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
-
PMID:7937876
-
Herman JG, Latif F, Weng Y, Lerman MI, Zbar B, Liu S, et al. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Natl Acad Sci U S A 1994; 91:9700-4; PMID:7937876; http://dx.doi.org/10.1073/pnas.91.21.9700.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 9700-9704
-
-
Herman, J.G.1
Latif, F.2
Weng, Y.3
Lerman, M.I.4
Zbar, B.5
Liu, S.6
-
25
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
PMID:7553621
-
Herman JG, Merlo A, Mao L, Lapidus RG, Issa JP, Davidson NE, et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 1995; 55:4525-30; PMID:7553621.
-
(1995)
Cancer Res
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.P.5
Davidson, N.E.6
-
26
-
-
34547779010
-
Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors
-
PMID:17645803
-
Costa VL, Henrique R, Ribeiro FR, Pinto M, Oliveira J, Lobo F, et al. Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors. BMC Cancer 2007; 7:133; PMID:17645803; http://dx.doi.org/10.1186/1471-2407-7-133.
-
(2007)
BMC Cancer
, vol.7
, pp. 133
-
-
Costa, V.L.1
Henrique, R.2
Ribeiro, F.R.3
Pinto, M.4
Oliveira, J.5
Lobo, F.6
-
27
-
-
0242437939
-
Multigene methylation analysis of Wilms' tumour and adult renal cell carcinoma
-
PMID:14555992
-
Morris MR, Hesson LB, Wagner KJ, Morgan NV, Astuti D, Lees RD, et al. Multigene methylation analysis of Wilms' tumour and adult renal cell carcinoma. Oncogene 2003; 22:6794-801; PMID:14555992; http://dx.doi.org/10.1038/sj.onc.1206914.
-
(2003)
Oncogene
, vol.22
, pp. 6794-6801
-
-
Morris, M.R.1
Hesson, L.B.2
Wagner, K.J.3
Morgan, N.V.4
Astuti, D.5
Lees, R.D.6
-
28
-
-
66349100709
-
Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney
-
PMID:19470766
-
Beroukhim R, Brunet JP, Di Napoli A, Mertz KD, Seeley A, Pires MM, et al. Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer Res 2009; 69:4674-81; PMID:19470766; http://dx.doi.org/10.1158/0008-5472.CAN-09-0146.
-
(2009)
Cancer Res
, vol.69
, pp. 4674-4681
-
-
Beroukhim, R.1
Brunet, J.P.2
Di Napoli, A.3
Mertz, K.D.4
Seeley, A.5
Pires, M.M.6
-
29
-
-
0032146118
-
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability
-
PMID:9699680
-
Cunningham JM, Christensen ER, Tester DJ, Kim CY, Roche PC, Burgart LJ, et al. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. Cancer Res 1998; 58:3455-60; PMID:9699680.
-
(1998)
Cancer Res
, vol.58
, pp. 3455-3460
-
-
Cunningham, J.M.1
Christensen, E.R.2
Tester, D.J.3
Kim, C.Y.4
Roche, P.C.5
Burgart, L.J.6
-
30
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
PMID:9618505
-
Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci U S A 1998; 95:6870-5; PMID:9618505; http://dx.doi.org/10.1073/pnas.95.12.6870.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
Graff, J.R.4
Ahuja, N.5
Issa, J.P.6
-
31
-
-
0031017268
-
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
-
PMID:9041175
-
Kane MF, Loda M, Gaida GM, Lipman J, Mishra R, Goldman H, et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 1997; 57:808-11; PMID:9041175.
-
(1997)
Cancer Res
, vol.57
, pp. 808-811
-
-
Kane, M.F.1
Loda, M.2
Gaida, G.M.3
Lipman, J.4
Mishra, R.5
Goldman, H.6
-
32
-
-
13144307115
-
Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
-
PMID:9671741
-
Veigl ML, Kasturi L, Olechnowicz J, Ma AH, Lutterbaugh JD, Periyasamy S, et al. Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers. Proc Natl Acad Sci U S A 1998; 95:8698-702; PMID:9671741; http://dx.doi.org/10.1073/pnas.95.15.8698.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8698-8702
-
-
Veigl, M.L.1
Kasturi, L.2
Olechnowicz, J.3
Ma, A.H.4
Lutterbaugh, J.D.5
Periyasamy, S.6
-
33
-
-
34250802601
-
Gene methylation and early detection of genitourinary cancer: The road ahead
-
PMID:17585333
-
Cairns P. Gene methylation and early detection of genitourinary cancer: the road ahead. Nat Rev Cancer 2007; 7:531-43; PMID:17585333; http://dx.doi. org/10.1038/nrc2170.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 531-543
-
-
Cairns, P.1
-
34
-
-
79959825588
-
Translational application of epigenetic alterations: Ovarian cancer as a model
-
PMID:21402071
-
Maradeo ME, Cairns P. Translational application of epigenetic alterations: ovarian cancer as a model. FEBS Lett 2011; 585:2112-20; PMID:21402071; http://dx.doi.org/10.1016/j.febslet.2011.03.016.
-
(2011)
FEBS Lett
, vol.585
, pp. 2112-2120
-
-
Maradeo, M.E.1
Cairns, P.2
-
35
-
-
67449147110
-
Targeting DNA methylation
-
PMID:19509174
-
Issa JP, Kantarjian HM. Targeting DNA methylation. Clin Cancer Res 2009; 15:3938-46; PMID:19509174; http://dx.doi.org/10.1158/1078-0432.CCR-08-2783.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3938-3946
-
-
Issa, J.P.1
Kantarjian, H.M.2
-
36
-
-
0037133565
-
Comprehensive analysis of CpG islands in human chromosomes 21 and 22
-
PMID:11891299
-
Takai D, Jones PA. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci U S A 2002; 99:3740-5; PMID:11891299; http://dx.doi.org/10.1073/pnas.052410099.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3740-3745
-
-
Takai, D.1
Jones, P.A.2
-
37
-
-
84856306090
-
Genome-wide DNA methylation profiling using Infinium® assay
-
PMID:22122642
-
Bibikova M, Le J, Barnes B, Saedinia-Melnyk S, Zhou L, Shen R, et al. Genome-wide DNA methylation profiling using Infinium® assay. Epigenomics 2009; 1:177-200; http://dx.doi.org/10.2217/epi.09.14; PMID:22122642.
-
(2009)
Epigenomics
, vol.1
, pp. 177-200
-
-
Bibikova, M.1
Le, J.2
Barnes, B.3
Saedinia-Melnyk, S.4
Zhou, L.5
Shen, R.6
-
38
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
PMID:17072317
-
Eckhardt F, Lewin J, Cortese R, Rakyan VK, Attwood J, Burger M, et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet 2006; 38:1378-85; PMID:17072317; http://dx.doi. org/10.1038/ng1909.
-
(2006)
Nat Genet
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
Rakyan, V.K.4
Attwood, J.5
Burger, M.6
-
39
-
-
6844242334
-
The UTX gene escapes X inactivation in mice and humans
-
PMID:9499428
-
Greenfield A, Carrel L, Pennisi D, Philippe C, Quaderi N, Siggers P, et al. The UTX gene escapes X inactivation in mice and humans. Hum Mol Genet 1998; 7:737-42; PMID:9499428; http://dx.doi.org/10.1093/hmg/7.4.737.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 737-742
-
-
Greenfield, A.1
Carrel, L.2
Pennisi, D.3
Philippe, C.4
Quaderi, N.5
Siggers, P.6
-
40
-
-
3543111497
-
Comparative sequence and x-inactivation analyses of a domain of escape in human xp11.2 and the conserved segment in mouse
-
PMID:15197169
-
Tsuchiya KD, Greally JM, Yi Y, Noel KP, Truong JP, Disteche CM. Comparative sequence and x-inactivation analyses of a domain of escape in human xp11.2 and the conserved segment in mouse. Genome Res 2004; 14:1275-84; PMID:15197169; http://dx.doi. org/10.1101/gr.2575904.
-
(2004)
Genome Res
, vol.14
, pp. 1275-1284
-
-
Tsuchiya, K.D.1
Greally, J.M.2
Yi, Y.3
Noel, K.P.4
Truong, J.P.5
Disteche, C.M.6
-
41
-
-
0036135224
-
Increasing incidence of all stages of kidney cancer in the last 2 decades in the United States: An analysis of surveillance, epidemiology and end results program data
-
PMID:11743275
-
Hock LM, Lynch J, Balaji KC. Increasing incidence of all stages of kidney cancer in the last 2 decades in the United States: an analysis of surveillance, epidemiology and end results program data. J Urol 2002; 167:57-60; PMID:11743275; http://dx.doi.org/10.1016/S0022-5347(05)65382-7.
-
(2002)
J Urol
, vol.167
, pp. 57-60
-
-
Hock, L.M.1
Lynch, J.2
Balaji, K.C.3
-
42
-
-
34547528183
-
DNA methylation: Bisulphite modification and analysis
-
PMID:17406479
-
Clark SJ, Statham A, Stirzaker C, Molloy PL, Frommer M. DNA methylation: bisulphite modification and analysis. Nat Protoc 2006; 1:2353-64; PMID:17406479; http://dx.doi.org/10.1038/nprot.2006.324.
-
(2006)
Nat Protoc
, vol.1
, pp. 2353-2364
-
-
Clark, S.J.1
Statham, A.2
Stirzaker, C.3
Molloy, P.L.4
Frommer, M.5
-
43
-
-
0030697141
-
Detection and measurement of PCR bias in quantitative methylation analysis of bisulphitetreated DNA
-
PMID:9336479
-
Warnecke PM, Stirzaker C, Melki JR, Millar DS, Paul CL, Clark SJ. Detection and measurement of PCR bias in quantitative methylation analysis of bisulphitetreated DNA. Nucleic Acids Res 1997; 25:4422-6; PMID:9336479; http://dx.doi.org/10.1093/nar/25.21.4422.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4422-4426
-
-
Warnecke, P.M.1
Stirzaker, C.2
Melki, J.R.3
Millar, D.S.4
Paul, C.L.5
Clark, S.J.6
-
44
-
-
0035407651
-
Bisulfite genomic sequencing: Systematic investigation of critical experimental parameters
-
PMID:11433041
-
Grunau C, Clark SJ, Rosenthal A. Bisulfite genomic sequencing: systematic investigation of critical experimental parameters. Nucleic Acids Res 2001; 29:E65-5; PMID:11433041; http://dx.doi.org/10.1093/nar/29.13.e65.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Grunau, C.1
Clark, S.J.2
Rosenthal, A.3
-
45
-
-
0038104379
-
Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions
-
PMID:12812984
-
Sandovici I, Leppert M, Hawk PR, Suarez A, Linares Y, Sapienza C. Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions. Hum Mol Genet 2003; 12:1569-78; PMID:12812984; http://dx.doi. org/10.1093/hmg/ddg167.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1569-1578
-
-
Sandovici, I.1
Leppert, M.2
Hawk, P.R.3
Suarez, A.4
Linares, Y.5
Sapienza, C.6
-
46
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
PMID:22397650
-
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012; 366:883-92; http://dx.doi.org/10.1056/NEJMoa1113205; PMID:22397650.
-
(2012)
N Engl J Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
-
47
-
-
33744932953
-
Identification of novel target genes by an epigenetic reactivation screen of renal cancer
-
PMID:16707423
-
Ibanez de Caceres I, Dulaimi E, Hoffman AM, Al-Saleem T, Uzzo RG, Cairns P. Identification of novel target genes by an epigenetic reactivation screen of renal cancer. Cancer Res 2006; 66:5021-8; PMID:16707423; http://dx.doi.org/10.1158/0008-5472.CAN-05-3365.
-
(2006)
Cancer Res
, vol.66
, pp. 5021-5028
-
-
Ibanez de Caceres, I.1
Dulaimi, E.2
Hoffman, A.M.3
Al-Saleem, T.4
Uzzo, R.G.5
Cairns, P.6
-
48
-
-
77956407479
-
Global reactivation of epigenetically silenced genes in prostate cancer
-
PMID:20699414
-
Ibragimova I, Ibáñez de Cáceres I, Hoffman AM, Potapova A, Dulaimi E, Al-Saleem T, et al. Global reactivation of epigenetically silenced genes in prostate cancer. Cancer Prev Res (Phila) 2010; 3:1084-92; PMID:20699414; http://dx.doi.org/10.1158/1940-6207.CAPR-10-0039.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1084-1092
-
-
Ibragimova, I.1
Ibáñez de Cáceres, I.2
Hoffman, A.M.3
Potapova, A.4
Dulaimi, E.5
Al-Saleem, T.6
-
49
-
-
0033545329
-
Detailed methylation analysis of the glutathione S-transferase pi (GSTP1) gene in prostate cancer
-
PMID:10022813
-
Millar DS, Ow KK, Paul CL, Russell PJ, Molloy PL, Clark SJ. Detailed methylation analysis of the glutathione S-transferase pi (GSTP1) gene in prostate cancer. Oncogene 1999; 18:1313-24; http://dx.doi. org/10.1038/sj.onc.1202415; PMID:10022813.
-
(1999)
Oncogene
, vol.18
, pp. 1313-1324
-
-
Millar, D.S.1
Ow, K.K.2
Paul, C.L.3
Russell, P.J.4
Molloy, P.L.5
Clark, S.J.6
-
50
-
-
0030925099
-
Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors
-
PMID:9187126
-
Stirzaker C, Millar DS, Paul CL, Warnecke PM, Harrison J, Vincent PC, et al. Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors. Cancer Res 1997; 57:2229-37; PMID:9187126.
-
(1997)
Cancer Res
, vol.57
, pp. 2229-2237
-
-
Stirzaker, C.1
Millar, D.S.2
Paul, C.L.3
Warnecke, P.M.4
Harrison, J.5
Vincent, P.C.6
-
51
-
-
84871194526
-
Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale
-
PMID:23066096
-
Barrera V, Peinado MA. Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale. Nucleic Acids Res 2012; 40:11490-8; PMID:23066096; http://dx.doi.org/10.1093/nar/gks928.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 11490-11498
-
-
Barrera, V.1
Peinado, M.A.2
-
52
-
-
78649969065
-
The DNA methylome of human peripheral blood mononuclear cells
-
PMID:21085693
-
Li Y, Zhu J, Tian G, Li N, Li Q, Ye M, et al. The DNA methylome of human peripheral blood mononuclear cells. PLoS Biol 2010; 8:e1000533; http://dx.doi. org/10.1371/journal.pbio.1000533; PMID:21085693.
-
(2010)
PLoS Biol
, vol.8
-
-
Li, Y.1
Zhu, J.2
Tian, G.3
Li, N.4
Li, Q.5
Ye, M.6
-
53
-
-
0028618304
-
Deletion of p16 and p15 genes in brain tumors
-
PMID:7987828
-
Jen J, Harper JW, Bigner SH, Bigner DD, Papadopoulos N, Markowitz S, et al. Deletion of p16 and p15 genes in brain tumors. Cancer Res 1994; 54:6353-8; PMID:7987828.
-
(1994)
Cancer Res
, vol.54
, pp. 6353-6358
-
-
Jen, J.1
Harper, J.W.2
Bigner, S.H.3
Bigner, D.D.4
Papadopoulos, N.5
Markowitz, S.6
-
54
-
-
0037068312
-
CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
-
PMID:12154405
-
Esteller M. CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene 2002; 21:5427-40; http://dx.doi. org/10.1038/sj.onc.1205600; PMID:12154405.
-
(2002)
Oncogene
, vol.21
, pp. 5427-5440
-
-
Esteller, M.1
-
55
-
-
66149173789
-
The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo
-
PMID:19487573
-
Huse JT, Brennan C, Hambardzumyan D, Wee B, Pena J, Rouhanifard SH, et al. The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo. Genes Dev 2009; 23:1327-37; PMID:19487573; http://dx.doi. org/10.1101/gad.1777409.
-
(2009)
Genes Dev
, vol.23
, pp. 1327-1337
-
-
Huse, J.T.1
Brennan, C.2
Hambardzumyan, D.3
Wee, B.4
Pena, J.5
Rouhanifard, S.H.6
-
56
-
-
34547524771
-
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
-
PMID:17681183
-
Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007; 133:647-58; PMID:17681183; http://dx.doi.org/10.1053/j.gastro. 2007.05.022.
-
(2007)
Gastroenterology
, vol.133
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
Patel, T.6
-
57
-
-
0034730127
-
Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation
-
PMID:10954755
-
Richon VM, Sandhoff TW, Rifkind RA, Marks PA. Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation. Proc Natl Acad Sci U S A 2000; 97:10014-9; PMID:10954755; http://dx.doi.org/10.1073/pnas.180316197.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10014-10019
-
-
Richon, V.M.1
Sandhoff, T.W.2
Rifkind, R.A.3
Marks, P.A.4
-
58
-
-
0004262043
-
-
A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press
-
Sambrook J, Russell DW. Molecular Cloning. A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, 2001.
-
(2001)
Molecular Cloning
-
-
Sambrook, J.1
Russell, D.W.2
-
59
-
-
0003104964
-
Chapter 5: New Human Tumor Cell Lines
-
In: Foch J, ed, New York and London: Plenum Press
-
Foch JaT. G. Chapter 5: New Human Tumor Cell Lines In: Foch J, ed. Human Tumor Cells in Vitro. New York and London: Plenum Press, 1975:115-59.
-
(1975)
Human Tumor Cells in Vitro
, pp. 115-159
-
-
Foch, J.T.G.1
-
60
-
-
0023216891
-
CpG islands in vertebrate genomes
-
PMID:3656447
-
Gardiner-Garden M, Frommer M. CpG islands in vertebrate genomes. J Mol Biol 1987; 196:261-82; PMID:3656447; http://dx.doi.org/10.1016/0022-2836(87)90689-9.
-
(1987)
J Mol Biol
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
61
-
-
0020376310
-
Prognostic significance of morphologic parameters in renal cell carcinoma
-
PMID:7180965
-
Fuhrman SA, Lasky LC, Limas C. Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol 1982; 6:655-63; PMID:7180965; http://dx.doi.org/10.1097/00000478-198210000-00007.
-
(1982)
Am J Surg Pathol
, vol.6
, pp. 655-663
-
-
Fuhrman, S.A.1
Lasky, L.C.2
Limas, C.3
-
62
-
-
84924052965
-
-
AJCC Cancer Staging Manual Seventh Edition
-
Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A III. Chapter 43 Kidney. AJCC Cancer Staging Manual Seventh Edition 2009:479-90.
-
(2009)
Chapter 43 Kidney
, pp. 479-490
-
-
Edge, S.B.1
Byrd, D.R.2
Compton, C.C.3
Fritz, A.G.4
Greene, F.L.5
Trotti III, A.6
|