메뉴 건너뛰기




Volumn 6, Issue JUL, 2015, Pages

Hold your horSSEs: Controlling structure-selective endonucleases MUS81 and Yen1/GEN1

Author keywords

Cdc14; Cdc5 PLK1; Cdk; DNA repair; Holliday junction; Nuclease; Recombination; Replication

Indexed keywords

CHECKPOINT KINASE 2; CHECKPOINT KINASE RAD3; CYCLIN DEPENDENT KINASE; DNA BINDING PROTEIN; DNA TOPOISOMERASE; ENDONUCLEASE; ENDONUCLEASE GEN1; ENDONUCLEASE MUS81; ENDONUCLEASE YEN1; KARYOPHERIN; MULTIENZYME COMPLEX; MUS81 EME1 COMPLEX; MUS81 EME2 COMPLEX; MUS81 MMS4 COMPLEX; MUS81 SLX4 COMPLEX; NUCLEASE S1; PHOSPHOPROTEIN PHOSPHATASE CDC14; PROTEIN FEN1; PROTEIN MMS4 56E; PROTEIN RAD27; PROTEIN SLX4; RECQ HELICASE; UNCLASSIFIED DRUG;

EID: 84940106082     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2015.00253     Document Type: Short Survey
Times cited : (28)

References (95)
  • 1
    • 0035854342 scopus 로고    scopus 로고
    • Differential timing and control of noncrossover and crossover recombination during meiosis
    • Allers, T., and Lichten, M. (2001). Differential timing and control of noncrossover and crossover recombination during meiosis. Cell 106, 47-57. doi: 10.1016/S0092-8674(01)00416-0.
    • (2001) Cell , vol.106 , pp. 47-57
    • Allers, T.1    Lichten, M.2
  • 2
    • 84901358862 scopus 로고    scopus 로고
    • Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex
    • Amangyeld, T., Shin, Y. K., Lee, M., Kwon, B., and Seo, Y. S. (2014). Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex. Nucleic Acids Res. 42, 5846-5862. doi: 10.1093/nar/gku237.
    • (2014) Nucleic Acids Res , vol.42 , pp. 5846-5862
    • Amangyeld, T.1    Shin, Y.K.2    Lee, M.3    Kwon, B.4    Seo, Y.S.5
  • 3
    • 67649655954 scopus 로고    scopus 로고
    • Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination
    • Andersen, S. L., Bergstralh, D. T., Kohl, K. P., LaRocque, J. R., Moore, C. B., and Sekelsky, J. (2009). Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination. Mol. Cell 35, 128-135. doi: 10.1016/j.molcel.2009.06.019.
    • (2009) Mol. Cell , vol.35 , pp. 128-135
    • Andersen, S.L.1    Bergstralh, D.T.2    Kohl, K.P.3    LaRocque, J.R.4    Moore, C.B.5    Sekelsky, J.6
  • 4
    • 53549122238 scopus 로고    scopus 로고
    • RTEL1 maintains genomic stability by suppressing homologous recombination
    • Barber, L. J., Youds, J. L., Ward, J. D., McIlwraith, M. J., O'Neil, N. J., Petalcorin, M. I., et al. (2008). RTEL1 maintains genomic stability by suppressing homologous recombination. Cell 135, 261-271. doi: 10.1016/j.cell.2008.08.016.
    • (2008) Cell , vol.135 , pp. 261-271
    • Barber, L.J.1    Youds, J.L.2    Ward, J.D.3    McIlwraith, M.J.4    O'Neil, N.J.5    Petalcorin, M.I.6
  • 5
    • 84907047351 scopus 로고    scopus 로고
    • AtGEN1 and AtSEND1, two paralogs in Arabidopsis, possess Holliday junction resolvase activity
    • Bauknecht, M., and Kobbe, D. (2014). AtGEN1 and AtSEND1, two paralogs in Arabidopsis, possess Holliday junction resolvase activity. Plant Physiol. 166, 202-216. doi: 10.1104/pp.114.237834.
    • (2014) Plant Physiol , vol.166 , pp. 202-216
    • Bauknecht, M.1    Kobbe, D.2
  • 6
    • 84898034120 scopus 로고    scopus 로고
    • Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability
    • Blanco, M. G., Matos, J., and West, S. C. (2014). Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability. Mol. Cell 54, 94-106. doi: 10.1016/j.molcel.2014.02.011.
    • (2014) Mol. Cell , vol.54 , pp. 94-106
    • Blanco, M.G.1    Matos, J.2    West, S.C.3
  • 7
    • 0035900652 scopus 로고    scopus 로고
    • Mus81-Eme1 are essential components of a Holliday junction resolvase
    • Boddy, M. N., Gaillard, P. H., McDonald, W. H., Shanahan, P., Yates, J. R. III, and Russell, P. (2001). Mus81-Eme1 are essential components of a Holliday junction resolvase. Cell 107, 537-548. doi: 10.1016/S0092-8674(01)00536-0.
    • (2001) Cell , vol.107 , pp. 537-548
    • Boddy, M.N.1    Gaillard, P.H.2    McDonald, W.H.3    Shanahan, P.4    Yates, J.R.5    Russell, P.6
  • 8
    • 0034462093 scopus 로고    scopus 로고
    • Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1
    • Boddy, M. N., Lopez-Girona, A., Shanahan, P., Interthal, H., Heyer, W. D., and Russell, P. (2000). Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1. Mol. Cell. Biol. 20, 8758-8766. doi: 10.1128/MCB.20.23.8758-8766.2000.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 8758-8766
    • Boddy, M.N.1    Lopez-Girona, A.2    Shanahan, P.3    Interthal, H.4    Heyer, W.D.5    Russell, P.6
  • 9
    • 77649165394 scopus 로고    scopus 로고
    • Maintaining genome stability at the replication fork
    • Branzei, D., and Foiani, M. (2010). Maintaining genome stability at the replication fork. Nat. Rev. Mol. Cell Biol. 11, 208-219. doi: 10.1038/nrm2852.
    • (2010) Nat. Rev. Mol. Cell Biol , vol.11 , pp. 208-219
    • Branzei, D.1    Foiani, M.2
  • 10
    • 77950862944 scopus 로고    scopus 로고
    • Double Holliday junctions are intermediates of DNA break repair
    • Bzymek, M., Thayer, N. H., Oh, S. D., Kleckner, N., and Hunter, N. (2010). Double Holliday junctions are intermediates of DNA break repair. Nature 464, 937-941. doi: 10.1038/nature08868.
    • (2010) Nature , vol.464 , pp. 937-941
    • Bzymek, M.1    Thayer, N.H.2    Oh, S.D.3    Kleckner, N.4    Hunter, N.5
  • 11
    • 84886251421 scopus 로고    scopus 로고
    • Cooperative control of Holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases
    • Castor, D., Nair, N., Declais, A. C., Lachaud, C., Toth, R., Macartney, T. J., et al. (2013). Cooperative control of Holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases. Mol. Cell 52, 221-233. doi: 10.1016/j.molcel.2013.08.036.
    • (2013) Mol. Cell , vol.52 , pp. 221-233
    • Castor, D.1    Nair, N.2    Declais, A.C.3    Lachaud, C.4    Toth, R.5    Macartney, T.J.6
  • 12
    • 84923329344 scopus 로고    scopus 로고
    • Spatial control of the GEN1 Holliday junction resolvase ensures genome stability
    • Chan, Y. W., and West, S. C. (2014). Spatial control of the GEN1 Holliday junction resolvase ensures genome stability. Nat. Commun. 5, 4844. doi: 10.1038/ncomms5844.
    • (2014) Nat. Commun , vol.5 , pp. 4844
    • Chan, Y.W.1    West, S.C.2
  • 13
    • 18244405819 scopus 로고    scopus 로고
    • Human Mus81-associated endonuclease cleaves Holliday junctions in vitro
    • Chen, X. B., Melchionna, R., Denis, C. M., Gaillard, P. H., Blasina, A., Van de Weyer, I., et al. (2001). Human Mus81-associated endonuclease cleaves Holliday junctions in vitro. Mol. Cell 8, 1117-1127. doi: 10.1016/S1097-2765(01)00375-6.
    • (2001) Mol. Cell , vol.8 , pp. 1117-1127
    • Chen, X.B.1    Melchionna, R.2    Denis, C.M.3    Gaillard, P.H.4    Blasina, A.5    Van de Weyer, I.6
  • 14
    • 0043092025 scopus 로고    scopus 로고
    • Identification and characterization of the human mus81-eme1 endonuclease
    • Ciccia, A., Constantinou, A., and West, S. C. (2003). Identification and characterization of the human mus81-eme1 endonuclease. J. Biol. Chem. 278, 25172-25178. doi: 10.1074/jbc.M302882200.
    • (2003) J. Biol. Chem , vol.278 , pp. 25172-25178
    • Ciccia, A.1    Constantinou, A.2    West, S.C.3
  • 15
    • 33846799430 scopus 로고    scopus 로고
    • Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM
    • Ciccia, A., Ling, C., Coulthard, R., Yan, Z., Xue, Y., Meetei, A. R., et al. (2007). Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. Mol. Cell 25, 331-343. doi: 10.1016/j.molcel.2007.01.003.
    • (2007) Mol. Cell , vol.25 , pp. 331-343
    • Ciccia, A.1    Ling, C.2    Coulthard, R.3    Yan, Z.4    Xue, Y.5    Meetei, A.R.6
  • 16
    • 50649091874 scopus 로고    scopus 로고
    • Structural and functional relationships of the XPF/MUS81 family of proteins
    • Ciccia, A., McDonald, N., and West, S. C. (2008). Structural and functional relationships of the XPF/MUS81 family of proteins. Annu. Rev. Biochem. 77, 259-287. doi: 10.1146/annurev.biochem.77.070306.102408.
    • (2008) Annu. Rev. Biochem , vol.77 , pp. 259-287
    • Ciccia, A.1    McDonald, N.2    West, S.C.3
  • 17
    • 0037107402 scopus 로고    scopus 로고
    • Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities
    • Constantinou, A., Chen, X. B., McGowan, C. H., and West, S. C. (2002). Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities. EMBO J. 21, 5577-5585. doi: 10.1093/emboj/cdf554.
    • (2002) EMBO J , vol.21 , pp. 5577-5585
    • Constantinou, A.1    Chen, X.B.2    McGowan, C.H.3    West, S.C.4
  • 18
    • 79957983705 scopus 로고    scopus 로고
    • Meiotic recombination intermediates are resolved with minimal crossover formation during return-to-growth, an analogue of the mitotic cell cycle
    • Dayani, Y., Simchen, G., and Lichten, M. (2011). Meiotic recombination intermediates are resolved with minimal crossover formation during return-to-growth, an analogue of the mitotic cell cycle. PLoS Genet. 7:e1002083. doi: 10.1371/journal.pgen.1002083.
    • (2011) PLoS Genet , vol.7
    • Dayani, Y.1    Simchen, G.2    Lichten, M.3
  • 19
    • 0037854709 scopus 로고    scopus 로고
    • The Mus81/Mms4 endonuclease acts independently of double-Holliday junction resolution to promote a distinct subset of crossovers during meiosis in budding yeast
    • de los Santos, T., Hunter, N., Lee, C., Larkin, B., Loidl, J., and Hollingsworth, N. M. (2003). The Mus81/Mms4 endonuclease acts independently of double-Holliday junction resolution to promote a distinct subset of crossovers during meiosis in budding yeast. Genetics 164, 81-94.
    • (2003) Genetics , vol.164 , pp. 81-94
    • de los Santos, T.1    Hunter, N.2    Lee, C.3    Larkin, B.4    Loidl, J.5    Hollingsworth, N.M.6
  • 20
    • 0035697324 scopus 로고    scopus 로고
    • A role for MMS4 in the processing of recombination intermediates during meiosis in Saccharomyces cerevisiae
    • de los Santos, T., Loidl, J., Larkin, B., and Hollingsworth, N. M. (2001). A role for MMS4 in the processing of recombination intermediates during meiosis in Saccharomyces cerevisiae. Genetics 159, 1511-1525.
    • (2001) Genetics , vol.159 , pp. 1511-1525
    • de los Santos, T.1    Loidl, J.2    Larkin, B.3    Hollingsworth, N.M.4
  • 22
    • 0037031837 scopus 로고    scopus 로고
    • Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks
    • Doe, C. L., Ahn, J. S., Dixon, J., and Whitby, M. C. (2002). Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks. J. Biol. Chem. 277, 32753-32759. doi: 10.1074/jbc.M202120200.
    • (2002) J. Biol. Chem , vol.277 , pp. 32753-32759
    • Doe, C.L.1    Ahn, J.S.2    Dixon, J.3    Whitby, M.C.4
  • 23
    • 42449115326 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease
    • Ehmsen, K. T., and Heyer, W. D. (2008). Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease. Nucleic Acids Res. 36, 2182-2195. doi: 10.1093/nar/gkm1152.
    • (2008) Nucleic Acids Res , vol.36 , pp. 2182-2195
    • Ehmsen, K.T.1    Heyer, W.D.2
  • 24
    • 84898022907 scopus 로고    scopus 로고
    • The Cdk/cDc14 module controls activation of the Yen1 Holliday junction resolvase to promote genome stability
    • Eissler, C. L., Mazon, G., Powers, B. L., Savinov, S. N., Symington, L. S., and Hall, M. C. (2014). The Cdk/cDc14 module controls activation of the Yen1 Holliday junction resolvase to promote genome stability. Mol. Cell 54, 80-93. doi: 10.1016/j.molcel.2014.02.012.
    • (2014) Mol. Cell , vol.54 , pp. 80-93
    • Eissler, C.L.1    Mazon, G.2    Powers, B.L.3    Savinov, S.N.4    Symington, L.S.5    Hall, M.C.6
  • 25
    • 0037168658 scopus 로고    scopus 로고
    • Alternate pathways involving Sgs1/Top3, Mus81/Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication
    • Fabre, F., Chan, A., Heyer, W. D., and Gangloff, S. (2002). Alternate pathways involving Sgs1/Top3, Mus81/Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication. Proc. Natl. Acad. Sci. U.S.A. 99, 16887-16892. doi: 10.1073/pnas.252652399.
    • (2002) Proc. Natl. Acad. Sci. U.S.A , vol.99 , pp. 16887-16892
    • Fabre, F.1    Chan, A.2    Heyer, W.D.3    Gangloff, S.4
  • 26
    • 67649655402 scopus 로고    scopus 로고
    • Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases
    • Fekairi, S., Scaglione, S., Chahwan, C., Taylor, E. R., Tissier, A., Coulon, S., et al. (2009). Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. Cell 138, 78-89. doi: 10.1016/j.cell.2009.06.029.
    • (2009) Cell , vol.138 , pp. 78-89
    • Fekairi, S.1    Scaglione, S.2    Chahwan, C.3    Taylor, E.R.4    Tissier, A.5    Coulon, S.6
  • 27
    • 84914674775 scopus 로고    scopus 로고
    • GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes
    • Freeman, A. D., Liu, Y., Declais, A. C., Gartner, A., and Lilley, D. M. (2014). GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes. J. Mol. Biol. 426, 3946-3959. doi: 10.1016/j.jmb.2014.10.008.
    • (2014) J. Mol. Biol , vol.426 , pp. 3946-3959
    • Freeman, A.D.1    Liu, Y.2    Declais, A.C.3    Gartner, A.4    Lilley, D.M.5
  • 28
    • 10044292849 scopus 로고    scopus 로고
    • Substrate specificity of the Saccharomyces cerevisiae Mus81-Mms4 endonuclease
    • Fricke, W. M., Bastin-Shanower, S. A., and Brill, S. J. (2005). Substrate specificity of the Saccharomyces cerevisiae Mus81-Mms4 endonuclease. DNA Rep. (Amst.) 4, 243-251. doi: 10.1016/j.dnarep.2004.10.001.
    • (2005) DNA Rep. (Amst.) , vol.4 , pp. 243-251
    • Fricke, W.M.1    Bastin-Shanower, S.A.2    Brill, S.J.3
  • 29
    • 0038167328 scopus 로고    scopus 로고
    • Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3
    • Fricke, W. M., and Brill, S. J. (2003). Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3. Genes Dev. 17, 1768-1778. doi: 10.1101/gad.1105203.
    • (2003) Genes Dev , vol.17 , pp. 1768-1778
    • Fricke, W.M.1    Brill, S.J.2
  • 30
    • 0345724838 scopus 로고    scopus 로고
    • Functional domains required for the Saccharomyces cerevisiae Mus81-Mms4 endonuclease complex formation and nuclear localization
    • Fu, Y., and Xiao, W. (2003). Functional domains required for the Saccharomyces cerevisiae Mus81-Mms4 endonuclease complex formation and nuclear localization. DNA Rep. (Amst.) 2, 1435-1447. doi: 10.1016/j.dnarep.2003.08.013.
    • (2003) DNA Rep. (Amst.) , vol.2 , pp. 1435-1447
    • Fu, Y.1    Xiao, W.2
  • 32
    • 0141707818 scopus 로고    scopus 로고
    • The endogenous Mus81-Eme1 complex resolves Holliday junctions by a nick and counternick mechanism
    • Gaillard, P. H., Noguchi, E., Shanahan, P., and Russell, P. (2003). The endogenous Mus81-Eme1 complex resolves Holliday junctions by a nick and counternick mechanism. Mol. Cell 12, 747-759. doi: 10.1016/S1097-2765(03)00342-3.
    • (2003) Mol. Cell , vol.12 , pp. 747-759
    • Gaillard, P.H.1    Noguchi, E.2    Shanahan, P.3    Russell, P.4
  • 33
  • 34
    • 0028033989 scopus 로고
    • The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase
    • Gangloff, S., McDonald, J. P., Bendixen, C., Arthur, L., and Rothstein, R. (1994). The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol. Cell. Biol. 14, 8391-8398.
    • (1994) Mol. Cell. Biol , vol.14 , pp. 8391-8398
    • Gangloff, S.1    McDonald, J.P.2    Bendixen, C.3    Arthur, L.4    Rothstein, R.5
  • 35
    • 84899712412 scopus 로고    scopus 로고
    • Cdc14 targets the Holliday junction resolvase Yen1 to the nucleus in early anaphase
    • Garcia-Luis, J., Clemente-Blanco, A., Aragon, L., and Machin, F. (2014). Cdc14 targets the Holliday junction resolvase Yen1 to the nucleus in early anaphase. Cell Cycle 13, 1392-1399. doi: 10.4161/cc.28370.
    • (2014) Cell Cycle , vol.13 , pp. 1392-1399
    • Garcia-Luis, J.1    Clemente-Blanco, A.2    Aragon, L.3    Machin, F.4
  • 36
    • 84885855405 scopus 로고    scopus 로고
    • Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions
    • Garner, E., Kim, Y., Lach, F. P., Kottemann, M. C., and Smogorzewska, A. (2013). Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions. Cell Rep. 5, 207-215. doi: 10.1016/j.celrep.2013.08.041.
    • (2013) Cell Rep , vol.5 , pp. 207-215
    • Garner, E.1    Kim, Y.2    Lach, F.P.3    Kottemann, M.C.4    Smogorzewska, A.5
  • 37
    • 34247251492 scopus 로고    scopus 로고
    • Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?
    • Gaskell, L. J., Osman, F., Gilbert, R. J., and Whitby, M. C. (2007). Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates? EMBO J. 26, 1891-1901. doi: 10.1038/sj.emboj.7601645.
    • (2007) EMBO J , vol.26 , pp. 1891-1901
    • Gaskell, L.J.1    Osman, F.2    Gilbert, R.J.3    Whitby, M.C.4
  • 39
    • 84904302386 scopus 로고    scopus 로고
    • A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication
    • Gritenaite, D., Princz, L. N., Szakal, B., Bantele, S. C., Wendeler, L., Schilbach, S., et al. (2014). A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication. Genes Dev. 28, 1604-1619. doi: 10.1101/gad.240515.114.
    • (2014) Genes Dev , vol.28 , pp. 1604-1619
    • Gritenaite, D.1    Princz, L.N.2    Szakal, B.3    Bantele, S.C.4    Wendeler, L.5    Schilbach, S.6
  • 40
    • 0035977119 scopus 로고    scopus 로고
    • The fuss about Mus81
    • Haber, J. E., and Heyer, W. D. (2001). The fuss about Mus81. Cell 107, 551-554. doi: 10.1016/S0092-8674(01)00593-1.
    • (2001) Cell , vol.107 , pp. 551-554
    • Haber, J.E.1    Heyer, W.D.2
  • 41
    • 1142265873 scopus 로고    scopus 로고
    • Recombination: Holliday junction resolution and crossover formation
    • Heyer, W. D. (2004). Recombination: Holliday junction resolution and crossover formation. Curr. Biol. 14, R56-R58. doi: 10.1016/j.cub.2003.12.043.
    • (2004) Curr. Biol , vol.14 , pp. R56-R58
    • Heyer, W.D.1
  • 42
    • 78149425175 scopus 로고    scopus 로고
    • Regulation of homologous recombination in eukaryotes
    • Heyer, W. D., Ehmsen, K. T., and Liu, J. (2010). Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet. 44, 113-139. doi: 10.1146/annurev-genet-051710-150955.
    • (2010) Annu. Rev. Genet , vol.44 , pp. 113-139
    • Heyer, W.D.1    Ehmsen, K.T.2    Liu, J.3
  • 43
    • 0347571776 scopus 로고    scopus 로고
    • Holliday junctions in the eukaryotic nucleus: resolution in sight?
    • Heyer, W. D., Ehmsen, K. T., and Solinger, J. A. (2003). Holliday junctions in the eukaryotic nucleus: resolution in sight? Trends Biochem. Sci. 28, 548-557. doi: 10.1016/j.tibs.2003.08.011.
    • (2003) Trends Biochem. Sci , vol.28 , pp. 548-557
    • Heyer, W.D.1    Ehmsen, K.T.2    Solinger, J.A.3
  • 44
    • 55849102141 scopus 로고    scopus 로고
    • A mechanism for gene conversion in fungi
    • Holliday, R. (2007). A mechanism for gene conversion in fungi. Genet. Res. 89, 285-307. doi: 10.1017/S0016672308009476.
    • (2007) Genet. Res , vol.89 , pp. 285-307
    • Holliday, R.1
  • 45
    • 0942279596 scopus 로고    scopus 로고
    • The Mus81 solution to resolution: generating meiotic crossovers without Holliday junctions
    • Hollingsworth, N. M., and Brill, S. J. (2004). The Mus81 solution to resolution: generating meiotic crossovers without Holliday junctions. Genes Dev. 18, 117-125. doi: 10.1101/gad.1165904.
    • (2004) Genes Dev , vol.18 , pp. 117-125
    • Hollingsworth, N.M.1    Brill, S.J.2
  • 46
    • 0033830809 scopus 로고    scopus 로고
    • MUS81 encodes a novel helix-hairpin-helix protein involved in the response to UV-and methylation-induced DNA damage in Saccharomyces cerevisiae
    • Interthal, H., and Heyer, W. D. (2000). MUS81 encodes a novel helix-hairpin-helix protein involved in the response to UV-and methylation-induced DNA damage in Saccharomyces cerevisiae. Mol. Gen. Genet. 263, 812-827. doi: 10.1007/s004380000241.
    • (2000) Mol. Gen. Genet , vol.263 , pp. 812-827
    • Interthal, H.1    Heyer, W.D.2
  • 47
    • 56749119855 scopus 로고    scopus 로고
    • Identification of Holliday junction resolvases from humans and yeast
    • Ip, S. C., Rass, U., Blanco, M. G., Flynn, H. R., Skehel, J. M., and West, S. C. (2008). Identification of Holliday junction resolvases from humans and yeast. Nature 456, 357-361. doi: 10.1038/nature07470.
    • (2008) Nature , vol.456 , pp. 357-361
    • Ip, S.C.1    Rass, U.2    Blanco, M.G.3    Flynn, H.R.4    Skehel, J.M.5    West, S.C.6
  • 48
    • 0345447604 scopus 로고    scopus 로고
    • Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast
    • Ira, G., Malkova, A., Liberi, G., Foiani, M., and Haber, J. E. (2003). Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. Cell 115, 401-411. doi: 10.1016/S0092-8674(03)00886-9.
    • (2003) Cell , vol.115 , pp. 401-411
    • Ira, G.1    Malkova, A.2    Liberi, G.3    Foiani, M.4    Haber, J.E.5
  • 49
    • 0031846463 scopus 로고    scopus 로고
    • Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication
    • Johnson, R. E., Kovvali, G. K., Prakash, L., and Prakash, S. (1998). Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication. Curr. Genet. 34, 21-29. doi: 10.1007/s002940050362.
    • (1998) Curr. Genet , vol.34 , pp. 21-29
    • Johnson, R.E.1    Kovvali, G.K.2    Prakash, L.3    Prakash, S.4
  • 50
    • 17444416489 scopus 로고    scopus 로고
    • Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress
    • Kai, M., Boddy, M. N., Russell, P., and Wang, T. S. (2005). Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev. 19, 919-932. doi: 10.1101/gad.1304305.
    • (2005) Genes Dev , vol.19 , pp. 919-932
    • Kai, M.1    Boddy, M.N.2    Russell, P.3    Wang, T.S.4
  • 51
    • 0035886690 scopus 로고    scopus 로고
    • Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease
    • Kaliraman, V., Mullen, J. R., Fricke, W. M., Bastin-Shanower, S. A., and Brill, S. J. (2001). Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease. Genes Dev. 15, 2730-2740. doi: 10.1101/gad.932201.
    • (2001) Genes Dev , vol.15 , pp. 2730-2740
    • Kaliraman, V.1    Mullen, J.R.2    Fricke, W.M.3    Bastin-Shanower, S.A.4    Brill, S.J.5
  • 52
    • 34447622539 scopus 로고    scopus 로고
    • DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork
    • Kanai, Y., Ishikawa, G., Takeuchi, R., Ruike, T., Nakamura, R., Ihara, A., et al. (2007). DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork. FEBS J. 274, 3914-3927. doi: 10.1111/j.1742-4658.2007.05924.x.
    • (2007) FEBS J , vol.274 , pp. 3914-3927
    • Kanai, Y.1    Ishikawa, G.2    Takeuchi, R.3    Ruike, T.4    Nakamura, R.5    Ihara, A.6
  • 53
    • 78649819004 scopus 로고    scopus 로고
    • Genetic and functional interactions between Mus81-Mms4 and Rad27
    • Kang, M. J., Lee, C. H., Kang, Y. H., Cho, I. T., Nguyen, T. A., and Seo, Y. S. (2010). Genetic and functional interactions between Mus81-Mms4 and Rad27. Nucleic Acids Res. 38, 7611-7625. doi: 10.1093/nar/gkq651.
    • (2010) Nucleic Acids Res , vol.38 , pp. 7611-7625
    • Kang, M.J.1    Lee, C.H.2    Kang, Y.H.3    Cho, I.T.4    Nguyen, T.A.5    Seo, Y.S.6
  • 54
    • 84872082435 scopus 로고    scopus 로고
    • Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4
    • Kim, Y., Spitz, G. S., Veturi, U., Lach, F. P., Auerbach, A. D., and Smogorzewska, A. (2013). Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4. Blood 121, 54-63. doi: 10.1182/blood-2012-07-441212.
    • (2013) Blood , vol.121 , pp. 54-63
    • Kim, Y.1    Spitz, G.S.2    Veturi, U.3    Lach, F.P.4    Auerbach, A.D.5    Smogorzewska, A.6
  • 55
    • 67649845784 scopus 로고    scopus 로고
    • Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs
    • Kosugi, S., Hasebe, M., Tomita, M., and Yanagawa, H. (2009). Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs. Proc. Natl. Acad. Sci. U.S.A. 106, 10171-10176. doi: 10.1073/pnas.0900604106.
    • (2009) Proc. Natl. Acad. Sci. U.S.A , vol.106 , pp. 10171-10176
    • Kosugi, S.1    Hasebe, M.2    Tomita, M.3    Yanagawa, H.4
  • 56
    • 0031104841 scopus 로고    scopus 로고
    • The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair
    • Lieber, M. R. (1997). The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair. Bioessays 19, 233-240. doi: 10.1002/bies.950190309.
    • (1997) Bioessays , vol.19 , pp. 233-240
    • Lieber, M.R.1
  • 58
    • 8444248943 scopus 로고    scopus 로고
    • Happy Hollidays: 40th anniversary of the Holliday junction
    • Liu, Y., and West, S. C. (2004). Happy Hollidays: 40th anniversary of the Holliday junction. Nat. Rev. Mol. Cell Biol. 5, 937-944. doi: 10.1038/nrm1502.
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 937-944
    • Liu, Y.1    West, S.C.2
  • 59
    • 14544270984 scopus 로고    scopus 로고
    • Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates
    • Loog, M., and Morgan, D. O. (2005). Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates. Nature 434, 104-108. doi: 10.1038/nature03329.
    • (2005) Nature , vol.434 , pp. 104-108
    • Loog, M.1    Morgan, D.O.2
  • 60
    • 77951243565 scopus 로고    scopus 로고
    • The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant
    • Lorenz, A., West, S. C., and Whitby, M. C. (2010). The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant. Nucleic Acids Res. 38, 1866-1873. doi: 10.1093/nar/gkp1179.
    • (2010) Nucleic Acids Res , vol.38 , pp. 1866-1873
    • Lorenz, A.1    West, S.C.2    Whitby, M.C.3
  • 61
    • 80053544629 scopus 로고    scopus 로고
    • Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis
    • Matos, J., Blanco, M. G., Maslen, S., Skehel, J. M., and West, S. C. (2011). Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis. Cell 147, 158-172. doi: 10.1016/j.cell.2011.08.032.
    • (2011) Cell , vol.147 , pp. 158-172
    • Matos, J.1    Blanco, M.G.2    Maslen, S.3    Skehel, J.M.4    West, S.C.5
  • 62
    • 84892432014 scopus 로고    scopus 로고
    • Cell-cycle kinases coordinate the resolution of recombination intermediates with chromosome segregation
    • Matos, J., Blanco, M. G., and West, S. C. (2013). Cell-cycle kinases coordinate the resolution of recombination intermediates with chromosome segregation. Cell Rep. 4, 76-86. doi: 10.1016/j.celrep.2013.05.039.
    • (2013) Cell Rep , vol.4 , pp. 76-86
    • Matos, J.1    Blanco, M.G.2    West, S.C.3
  • 63
    • 84902075935 scopus 로고    scopus 로고
    • Holliday junction resolution: regulation in space and time
    • Matos, J., and West, S. C. (2014). Holliday junction resolution: regulation in space and time. DNA Rep. (Amst.) 19, 176-181. doi: 10.1016/j.dnarep.2014.03.013.
    • (2014) DNA Rep. (Amst.) , vol.19 , pp. 176-181
    • Matos, J.1    West, S.C.2
  • 64
    • 84924069316 scopus 로고    scopus 로고
    • Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements
    • Mohebi, S., Mizuno, K., Watson, A., Carr, A. M., and Murray, J. M. (2015). Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements. Nat. Commun. 6, 6357. doi: 10.1038/ncomms7357.
    • (2015) Nat. Commun , vol.6 , pp. 6357
    • Mohebi, S.1    Mizuno, K.2    Watson, A.3    Carr, A.M.4    Murray, J.M.5
  • 65
    • 34447527882 scopus 로고    scopus 로고
    • Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase
    • Moses, A. M., Heriche, J. K., and Durbin, R. (2007). Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase. Genome Biol. 8, R23. doi: 10.1186/gb-2007-8-2-r23.
    • (2007) Genome Biol , vol.8 , pp. R23
    • Moses, A.M.1    Heriche, J.K.2    Durbin, R.3
  • 66
    • 0035148955 scopus 로고    scopus 로고
    • Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae
    • Mullen, J. R., Kaliraman, V., Ibrahim, S. S., and Brill, S. J. (2001). Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics 157, 103-118.
    • (2001) Genetics , vol.157 , pp. 103-118
    • Mullen, J.R.1    Kaliraman, V.2    Ibrahim, S.S.3    Brill, S.J.4
  • 67
    • 67649641641 scopus 로고    scopus 로고
    • Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair
    • Munoz, I. M., Hain, K., Declais, A. C., Gardiner, M., Toh, G. W., Sanchez-Pulido, L., et al. (2009). Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Mol. Cell 35, 116-127. doi: 10.1016/j.molcel.2009.06.020.
    • (2009) Mol. Cell , vol.35 , pp. 116-127
    • Munoz, I.M.1    Hain, K.2    Declais, A.C.3    Gardiner, M.4    Toh, G.W.5    Sanchez-Pulido, L.6
  • 68
    • 84919777600 scopus 로고    scopus 로고
    • Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein
    • Nair, N., Castor, D., Macartney, T., and Rouse, J. (2014). Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein. DNA Rep. (Amst.) 24, 131-137. doi: 10.1016/j.dnarep.2014.08.004.
    • (2014) DNA Rep. (Amst.) , vol.24 , pp. 131-137
    • Nair, N.1    Castor, D.2    Macartney, T.3    Rouse, J.4
  • 69
    • 0038498093 scopus 로고    scopus 로고
    • Identification and characterization of human MUS81-MMS4 structure-specific endonuclease
    • Ogrunc, M., and Sancar, A. (2003). Identification and characterization of human MUS81-MMS4 structure-specific endonuclease. J. Biol. Chem. 278, 21715-21720. doi: 10.1074/jbc.M302484200.
    • (2003) J. Biol. Chem , vol.278 , pp. 21715-21720
    • Ogrunc, M.1    Sancar, A.2
  • 70
    • 0141707817 scopus 로고    scopus 로고
    • Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis
    • Osman, F., Dixon, J., Doe, C. L., and Whitby, M. C. (2003). Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis. Mol. Cell 12, 761-774. doi: 10.1016/S1097-2765(03)00343-5.
    • (2003) Mol. Cell , vol.12 , pp. 761-774
    • Osman, F.1    Dixon, J.2    Doe, C.L.3    Whitby, M.C.4
  • 71
    • 84901280865 scopus 로고    scopus 로고
    • MUS81-EME2 promotes replication fork restart
    • Pepe, A., and West, S. C. (2014a). MUS81-EME2 promotes replication fork restart. Cell Rep. 7, 1048-1055. doi: 10.1016/j.celrep.2014.04.007.
    • (2014) Cell Rep , vol.7 , pp. 1048-1055
    • Pepe, A.1    West, S.C.2
  • 72
    • 84898965087 scopus 로고    scopus 로고
    • Substrate specificity of the MUS81-EME2 structure selective endonuclease
    • Pepe, A., and West, S. C. (2014b). Substrate specificity of the MUS81-EME2 structure selective endonuclease. Nucleic Acids Res. 42, 3833-3845. doi: 10.1093/nar/gkt1333.
    • (2014) Nucleic Acids Res , vol.42 , pp. 3833-3845
    • Pepe, A.1    West, S.C.2
  • 73
    • 0037459072 scopus 로고    scopus 로고
    • Un menage a quatre: the molecular biology of chromosome segregation in meiosis
    • Petronczki, M., Siomos, M. F., and Nasmyth, K. (2003). Un menage a quatre: the molecular biology of chromosome segregation in meiosis. Cell 112, 423-440. doi: 10.1016/S0092-8674(03)00083-7.
    • (2003) Cell , vol.112 , pp. 423-440
    • Petronczki, M.1    Siomos, M.F.2    Nasmyth, K.3
  • 74
    • 58149494717 scopus 로고    scopus 로고
    • Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination
    • Prakash, R., Satory, D., Dray, E., Papusha, A., Scheller, J., Kramer, W., et al. (2009). Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination. Genes Dev. 23, 67-79. doi: 10.1101/gad.1737809.
    • (2009) Genes Dev , vol.23 , pp. 67-79
    • Prakash, R.1    Satory, D.2    Dray, E.3    Papusha, A.4    Scheller, J.5    Kramer, W.6
  • 75
    • 84896874313 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions
    • Ranjha, L., Anand, R., and Cejka, P. (2014). The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions. J. Biol. Chem. 289, 5674-5686. doi: 10.1074/jbc.M113.533810.
    • (2014) J. Biol. Chem , vol.289 , pp. 5674-5686
    • Ranjha, L.1    Anand, R.2    Cejka, P.3
  • 76
    • 84889088229 scopus 로고    scopus 로고
    • Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes
    • Rass, U. (2013). Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes. Chromosoma 122, 499-515. doi: 10.1007/s00412-013-0431-z.
    • (2013) Chromosoma , vol.122 , pp. 499-515
    • Rass, U.1
  • 77
    • 77954838714 scopus 로고    scopus 로고
    • Mechanism of Holliday junction resolution by the human GEN1 protein
    • Rass, U., Compton, S. A., Matos, J., Singleton, M. R., Ip, S. C., Blanco, M. G., et al. (2010). Mechanism of Holliday junction resolution by the human GEN1 protein. Genes Dev. 24, 1559-1569. doi: 10.1101/gad.585310.
    • (2010) Genes Dev , vol.24 , pp. 1559-1569
    • Rass, U.1    Compton, S.A.2    Matos, J.3    Singleton, M.R.4    Ip, S.C.5    Blanco, M.G.6
  • 78
    • 84896858213 scopus 로고    scopus 로고
    • Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease
    • Rogacheva, M. V., Manhart, C. M., Chen, C., Guarne, A., Surtees, J., and Alani, E. (2014). Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease. J. Biol. Chem. 289, 5664-5673. doi: 10.1074/jbc.M113.534644.
    • (2014) J. Biol. Chem , vol.289 , pp. 5664-5673
    • Rogacheva, M.V.1    Manhart, C.M.2    Chen, C.3    Guarne, A.4    Surtees, J.5    Alani, E.6
  • 79
    • 0028972024 scopus 로고
    • Identification of double Holliday junctions as intermediates in meiotic recombination
    • Schwacha, A., and Kleckner, N. (1995). Identification of double Holliday junctions as intermediates in meiotic recombination. Cell 83, 783-791. doi: 10.1016/0092-8674(95)90191-4.
    • (1995) Cell , vol.83 , pp. 783-791
    • Schwacha, A.1    Kleckner, N.2
  • 80
    • 79955522790 scopus 로고    scopus 로고
    • Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes
    • Schwartz, E. K., and Heyer, W. D. (2011). Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes. Chromosoma 120, 109-127. doi: 10.1007/s00412-010-0304-7.
    • (2011) Chromosoma , vol.120 , pp. 109-127
    • Schwartz, E.K.1    Heyer, W.D.2
  • 81
    • 84864592240 scopus 로고    scopus 로고
    • Mus81-Mms4 functions as a single heterodimer to cleave nicked intermediates in recombinational DNA repair
    • Schwartz, E. K., Wright, W. D., Ehmsen, K. T., Evans, J. E., Stahlberg, H., and Heyer, W. D. (2012). Mus81-Mms4 functions as a single heterodimer to cleave nicked intermediates in recombinational DNA repair. Mol. Cell. Biol. 32, 3065-3080. doi: 10.1128/MCB.00547-12.
    • (2012) Mol. Cell. Biol , vol.32 , pp. 3065-3080
    • Schwartz, E.K.1    Wright, W.D.2    Ehmsen, K.T.3    Evans, J.E.4    Stahlberg, H.5    Heyer, W.D.6
  • 82
    • 67649662604 scopus 로고    scopus 로고
    • Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
    • Svendsen, J. M., Smogorzewska, A., Sowa, M. E., O'Connell, B. C., Gygi, S. P., Elledge, S. J., et al. (2009). Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Cell 138, 63-77. doi: 10.1016/j.cell.2009.06.030.
    • (2009) Cell , vol.138 , pp. 63-77
    • Svendsen, J.M.1    Smogorzewska, A.2    Sowa, M.E.3    O'Connell, B.C.4    Gygi, S.P.5    Elledge, S.J.6
  • 83
    • 80755187806 scopus 로고    scopus 로고
    • Double-strand break end resection and repair pathway choice
    • Symington, L. S., and Gautier, J. (2011). Double-strand break end resection and repair pathway choice. Annu. Rev. Genet. 45, 247-271. doi: 10.1146/annurev-genet-110410-132435.
    • (2011) Annu. Rev. Genet , vol.45 , pp. 247-271
    • Symington, L.S.1    Gautier, J.2
  • 84
    • 84876407519 scopus 로고    scopus 로고
    • Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover
    • Szakal, B., and Branzei, D. (2013). Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover. EMBO J. 32, 1155-1167. doi: 10.1038/emboj.2013.67.
    • (2013) EMBO J , vol.32 , pp. 1155-1167
    • Szakal, B.1    Branzei, D.2
  • 85
    • 84936137430 scopus 로고    scopus 로고
    • A physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repair
    • Thu, H. P., Nguyen, T. A., Munashingha, P. R., Kwon, B., Dao Van, Q., and Seo, Y. S. (2015). A physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repair. Nucleic Acids Res. 43, 1684-1699. doi: 10.1093/nar/gkv025.
    • (2015) Nucleic Acids Res , vol.43 , pp. 1684-1699
    • Thu, H.P.1    Nguyen, T.A.2    Munashingha, P.R.3    Kwon, B.4    Dao Van, Q.5    Seo, Y.S.6
  • 86
    • 79953894934 scopus 로고    scopus 로고
    • Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily
    • Tsutakawa, S. E., Classen, S., Chapados, B. R., Arvai, A. S., Finger, L. D., Guenther, G., et al. (2011). Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. Cell 145, 198-211. doi: 10.1016/j.cell.2011.03.004.
    • (2011) Cell , vol.145 , pp. 198-211
    • Tsutakawa, S.E.1    Classen, S.2    Chapados, B.R.3    Arvai, A.S.4    Finger, L.D.5    Guenther, G.6
  • 87
    • 84902119190 scopus 로고    scopus 로고
    • The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once
    • Tsutakawa, S. E., Lafrance-Vanasse, J., and Tainer, J. A. (2014). The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once. DNA Rep. (Amst.) 19, 95-107. doi: 10.1016/j.dnarep.2014.03.022.
    • (2014) DNA Rep. (Amst.) , vol.19 , pp. 95-107
    • Tsutakawa, S.E.1    Lafrance-Vanasse, J.2    Tainer, J.A.3
  • 89
    • 79953239469 scopus 로고    scopus 로고
    • Aberrant chromosome morphology in human cells defective for Holliday junction resolution
    • Wechsler, T., Newman, S., and West, S. C. (2011). Aberrant chromosome morphology in human cells defective for Holliday junction resolution. Nature 471, 642-646. doi: 10.1038/nature09790.
    • (2011) Nature , vol.471 , pp. 642-646
    • Wechsler, T.1    Newman, S.2    West, S.C.3
  • 90
    • 0031453378 scopus 로고    scopus 로고
    • Processing of recombination intermediates by the RuvABC proteins
    • West, S. C. (1997). Processing of recombination intermediates by the RuvABC proteins. Annu. Rev. Genet. 31, 213-244. doi: 10.1146/annurev.genet.31.1.213.
    • (1997) Annu. Rev. Genet , vol.31 , pp. 213-244
    • West, S.C.1
  • 91
    • 0347987856 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase suppresses crossing over during homologous recombination
    • Wu, L., and Hickson, I. D. (2003). The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 426, 870-874. doi: 10.1038/nature02253.
    • (2003) Nature , vol.426 , pp. 870-874
    • Wu, L.1    Hickson, I.D.2
  • 92
    • 84886241606 scopus 로고    scopus 로고
    • Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells
    • Wyatt, H. D., Sarbajna, S., Matos, J., and West, S. C. (2013). Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells. Mol. Cell 52, 234-247. doi: 10.1016/j.molcel.2013.08.035.
    • (2013) Mol. Cell , vol.52 , pp. 234-247
    • Wyatt, H.D.1    Sarbajna, S.2    Matos, J.3    West, S.C.4
  • 93
    • 0031941079 scopus 로고    scopus 로고
    • Mms4, a putative transcriptional (co)activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage
    • Xiao, W., Chow, B. L., and Milo, C. N. (1998). Mms4, a putative transcriptional (co)activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage. Mol. Gen. Genet. 257, 614-623. doi: 10.1007/s004380050689.
    • (1998) Mol. Gen. Genet , vol.257 , pp. 614-623
    • Xiao, W.1    Chow, B.L.2    Milo, C.N.3
  • 94
    • 84863286568 scopus 로고    scopus 로고
    • The OsGEN-L protein from Oryza sativa possesses Holliday junction resolvase activity as well as 5'-flap endonuclease activity
    • Yang, Y., Ishino, S., Yamagami, T., Kumamaru, T., Satoh, H., and Ishino, Y. (2012). The OsGEN-L protein from Oryza sativa possesses Holliday junction resolvase activity as well as 5'-flap endonuclease activity. J. Biochem. 151, 317-327. doi: 10.1093/jb/mvr145.
    • (2012) J. Biochem , vol.151 , pp. 317-327
    • Yang, Y.1    Ishino, S.2    Yamagami, T.3    Kumamaru, T.4    Satoh, H.5    Ishino, Y.6
  • 95
    • 84859714621 scopus 로고    scopus 로고
    • Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase
    • Zakharyevich, K., Tang, S., Ma, Y., and Hunter, N. (2012). Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase. Cell 149, 334-347. doi: 10.1016/j.cell.2012.03.023.
    • (2012) Cell , vol.149 , pp. 334-347
    • Zakharyevich, K.1    Tang, S.2    Ma, Y.3    Hunter, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.