Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein

DNA Repair

Volumn 24, Issue , 2014, Pages 131-137

  Nair, Nidhi ^a   Castor, Dennis ^a   Macartney, Thomas ^a   Rouse, John ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Inter strand crosslink; MUS81; Nuclease; Scaffold; SLX4

Indexed keywords

ALANINE; AMINO ACID; ENDONUCLEASE; MITOMYCIN; MUS81 PROTEIN; SCAFFOLD PROTEIN; SLX4 PROTEIN; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE; DNA BINDING PROTEIN; EME1 PROTEIN, MOUSE; MUS81 PROTEIN, HUMAN; MUS81 PROTEIN, MOUSE; RECOMBINASE; SLX4 PROTEIN, HUMAN;

ALLELE; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; DNA CROSS LINKING; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE MAPPING; HCT116 CELL LINE; HEK293 CELL LINE; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MUTANT; POINT MUTATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; TWO HYBRID SYSTEM; AMINO ACID SEQUENCE; DRUG EFFECTS; GENE INACTIVATION; GENETICS; METABOLISM; MOLECULAR GENETICS;

METAZOA; MURINAE;

AMINO ACID SEQUENCE; DNA REPAIR; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; ENDONUCLEASES; GENE KNOCKOUT TECHNIQUES; HCT116 CELLS; HEK293 CELLS; HUMANS; MITOMYCIN; MOLECULAR SEQUENCE DATA; POINT MUTATION; RECOMBINASES; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 84919777600     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2014.08.004     Document Type: Article

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