DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork

FEBS Journal

Volumn 274, Issue 15, 2007, Pages 3914-3927

  Kanai, Yoshihiro ^a   Ishikawa, Gen ^a   Takeuchi, Ryo ^a   Ruike, Tatsushi ^a   Nakamura, Ryo Ichi ^a   Ihara, Ayumi ^a   Ohashi, Tetsuyuki ^a   Takata, Kei Ichi ^a   Kimura, Seisuke ^a   Sakaguchi, Kengo ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Active site mutant; DmGEN; Novel flap endonuclease; Nuclease activity; Site directed mutagenesis

Indexed keywords

DROSOPHILA MELANOGASTER XPG LIKE ENDONUCLEASE; ENDONUCLEASE; EXONUCLEASE; FLAP ENDONUCLEASE; MUTANT PROTEIN; NUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EMBRYO; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN FUNCTION;

AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; DNA; DNA REPLICATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENDONUCLEASES; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

DROSOPHILA MELANOGASTER;

EID: 34447622539     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.05924.x     Document Type: Article

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