Forkhead box O6 (FoxO6) depletion attenuates hepatic gluconeogenesis and protects against fat-induced glucose disorder in mice

Journal of Biological Chemistry

Volumn 290, Issue 25, 2015, Pages 15581-15594

  Calabuig Navarro, Virtu ^a   Yamauchi, Jun ^a,b   Lee, Sojin ^a   Zhang, Ting ^a   Liu, Yun Zi ^a,c   Sadlek, Kelsey ^a   Coudriet, Gina M ^d   Piganelli, Jon D ^d   Jiang, Chun Lei ^c   Miller, Rita ^a   Lowe, Mark ^a   Harashima, Hideyoshi ^b   Dong, H Henry ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b HOKKAIDO UNIVERSITY   (Japan)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HISTOLOGY; INSULIN; MACROPHAGES; METABOLISM; TISSUE;

BLOOD GLUCOSE LEVEL; CHEMOKINE RECEPTORS; GLUCOSE INTOLERANCE; HEPATIC GLUCONEOGENESIS; INSULIN SENSITIVITY; MACROPHAGE INFILTRATIONS; PATHOLOGICAL CONDITIONS; PRIMARY HEPATOCYTES;

MAMMALS;

CHEMOKINE RECEPTOR CCR2; FAT; FORKHEAD BOX O6; FORKHEAD TRANSCRIPTION FACTOR; GLUCAGON; GLUCOSE; INSULIN; UNCLASSIFIED DRUG; CCR2 PROTEIN, MOUSE; FAT INTAKE; FOXO6PROTEIN, MOUSE;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; EMBRYO; FEMALE; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HEPATIC GLUCONEOGENESIS; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; LIPID DIET; LIVER; LIVER CELL; MACROPHAGE MIGRATION; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; ADVERSE EFFECTS; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED; DRUG EFFECTS; FAT INTAKE; GENETICS; HYPERINSULINISM; MACROPHAGE; METABOLISM; PATHOLOGY; PHARMACOLOGY;

MUS;

ADIPOSE TISSUE; ANIMALS; CELLS, CULTURED; DIETARY FATS; FORKHEAD TRANSCRIPTION FACTORS; GLUCONEOGENESIS; HYPERGLYCEMIA; HYPERINSULINISM; LIVER; MACROPHAGES; MICE; MICE, KNOCKOUT; RECEPTORS, CCR2;

EID: 84940069349     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.650994     Document Type: Article

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