메뉴 건너뛰기




Volumn 147, Issue 12, 2006, Pages 5641-5652

Aberrant forkhead box O1 function is associated with impaired hepatic metabolism

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; FATTY ACID SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

EID: 33751507689     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0541     Document Type: Article
Times cited : (103)

References (39)
  • 1
    • 0026520193 scopus 로고
    • Molecular physiology of the regulation of hepatic gluconeogenesis and glycogenolysis
    • Pilkis SJ, Granner DK 1992 Molecular physiology of the regulation of hepatic gluconeogenesis and glycogenolysis. Annu Rev Physiol 54:885-909
    • (1992) Annu Rev Physiol , vol.54 , pp. 885-909
    • Pilkis, S.J.1    Granner, D.K.2
  • 2
    • 0031748899 scopus 로고    scopus 로고
    • Relative contribution of glycogenolysis and gluconeogenesis to hepatic glucose production in control and diabetic rats. a re-examination in the presence of euglyceamia
    • Giaccari A, Morviducci L, Pastore L, Zorretta D, Sbraccia P, Maroccia E, Buongiorno A, Tamburrano G 1998 Relative contribution of glycogenolysis and gluconeogenesis to hepatic glucose production in control and diabetic rats. A re-examination in the presence of euglyceamia. Diabetologia 41:307-314
    • (1998) Diabetologia , vol.41 , pp. 307-314
    • Giaccari, A.1    Morviducci, L.2    Pastore, L.3    Zorretta, D.4    Sbraccia, P.5    Maroccia, E.6    Buongiorno, A.7    Tamburrano, G.8
  • 3
    • 0026488079 scopus 로고
    • Increased rate of gluconeogenesis in type II diabetes mellitus: A 13C nuclear magnetic resonance study
    • Magnuson MA, Rothman DL, Katz LD, Shulman RG, Shulman GI 1992 Increased rate of gluconeogenesis in type II diabetes mellitus: a 13C nuclear magnetic resonance study. J Clin Invest 90:1322-1327
    • (1992) J Clin Invest , vol.90 , pp. 1322-1327
    • Magnuson, M.A.1    Rothman, D.L.2    Katz, L.D.3    Shulman, R.G.4    Shulman, G.I.5
  • 4
    • 0035011295 scopus 로고    scopus 로고
    • Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus
    • Boden G, Chen X, Stein TP 2001 Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus. Am J Physiol Endocrinol Metab 280:E23-E30
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Boden, G.1    Chen, X.2    Stein, T.P.3
  • 5
    • 0342614209 scopus 로고    scopus 로고
    • Unified nomenclature for the winged helix/forkhead transcription factors
    • Kaestner KH, Knochel W, Martinez DE 2000 Unified nomenclature for the winged helix/forkhead transcription factors. Gene Dev 14:142-146
    • (2000) Gene Dev , vol.14 , pp. 142-146
    • Kaestner, K.H.1    Knochel, W.2    Martinez, D.E.3
  • 6
    • 0033522897 scopus 로고    scopus 로고
    • Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a wortmannin-sensitive pathway
    • Nakae J, Park B-C, Accili D 1999 Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a wortmannin-sensitive pathway. J Biol Chem 274:15982-15985
    • (1999) J Biol Chem , vol.274 , pp. 15982-15985
    • Nakae, J.1    Park, B.-C.2    Accili, D.3
  • 7
    • 0034161544 scopus 로고    scopus 로고
    • Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR
    • Nakae J, Barr V, Accili D 2000 Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR. EMBO J 19:989-996
    • (2000) EMBO J , vol.19 , pp. 989-996
    • Nakae, J.1    Barr, V.2    Accili, D.3
  • 9
    • 0032759047 scopus 로고    scopus 로고
    • Forkhead transcription factors: New insights into protein kinase B (c-akt) signaling
    • Kops GJ, Burgering BM 1999 Forkhead transcription factors: new insights into protein kinase B (c-akt) signaling. J Mol Med 77:656-665
    • (1999) J Mol Med , vol.77 , pp. 656-665
    • Kops, G.J.1    Burgering, B.M.2
  • 10
    • 0034254446 scopus 로고    scopus 로고
    • A member of forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phophatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction
    • Kashii Y, Uchida M, Kirito K, Tanaka M, Nishijima K, Toshima M, Ando T, Koizumi K, Endoh T, Sawada K, Momoi M, Ozawa K, Komatsu N 2000 A member of forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phophatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction. Hematopoisis 96:941-949
    • (2000) Hematopoisis , vol.96 , pp. 941-949
    • Kashii, Y.1    Uchida, M.2    Kirito, K.3    Tanaka, M.4    Nishijima, K.5    Toshima, M.6    Ando, T.7    Koizumi, K.8    Endoh, T.9    Sawada, K.10    Momoi, M.11    Ozawa, K.12    Komatsu, N.13
  • 11
    • 0030657540 scopus 로고    scopus 로고
    • Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • Lin K, Dorman JB, Rodan A, Kenyon C 1997 Daf-16: an HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278:1319
    • (1997) Science , vol.278 , pp. 1319
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 12
    • 2342496712 scopus 로고    scopus 로고
    • FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
    • Accili D, Arden KC 2004 FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 117:421-426
    • (2004) Cell , vol.117 , pp. 421-426
    • Accili, D.1    Arden, K.C.2
  • 13
    • 0036787607 scopus 로고    scopus 로고
    • Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
    • Nakae J, Biggs WH, Kitamura T, Cavenee W, Wright CVE, Arden KC, Accili D 2002 Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat Genet 32:245-253
    • (2002) Nat Genet , vol.32 , pp. 245-253
    • Nakae, J.1    Biggs, W.H.2    Kitamura, T.3    Cavenee, W.4    Wright, C.V.E.5    Arden, K.C.6    Accili, D.7
  • 17
    • 0035185021 scopus 로고    scopus 로고
    • The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
    • Nakae J, Kitamura T, Silver DL, Accili D 2001 The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J Clin Invest 108:1359-1367
    • (2001) J Clin Invest , vol.108 , pp. 1359-1367
    • Nakae, J.1    Kitamura, T.2    Silver, D.L.3    Accili, D.4
  • 18
    • 0036091935 scopus 로고    scopus 로고
    • Basal insulin gene expression significantly improves conventional insulin therapy in type 1 diabetic rats
    • Dong H, Altomonte J, Morral N, Meseck M, Thung SN, Woo SLC 2002 Basal insulin gene expression significantly improves conventional insulin therapy in type 1 diabetic rats. Diabetes 51:130-138
    • (2002) Diabetes , vol.51 , pp. 130-138
    • Dong, H.1    Altomonte, J.2    Morral, N.3    Meseck, M.4    Thung, S.N.5    Woo, S.L.C.6
  • 19
    • 0030666933 scopus 로고    scopus 로고
    • Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele
    • Rossetti L, Chen W, Hu M, Hawkins M, Barzilai N, Efrat S 1997 Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele. Am J Physiol 273:E743-E750
    • (1997) Am J Physiol , vol.273
    • Rossetti, L.1    Chen, W.2    Hu, M.3    Hawkins, M.4    Barzilai, N.5    Efrat, S.6
  • 20
    • 0042888597 scopus 로고    scopus 로고
    • Fat-depot specific expression of adiponectin is impaired in Zucker fatty rats
    • Altomonte J, Harbaran S, Richter A, Dong H 2003 Fat-depot specific expression of adiponectin is impaired in Zucker fatty rats. Metabolism 52:958-963
    • (2003) Metabolism , vol.52 , pp. 958-963
    • Altomonte, J.1    Harbaran, S.2    Richter, A.3    Dong, H.4
  • 22
    • 0028915634 scopus 로고
    • The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants
    • Huard J, Lochmüller H, Acsadi G, Jani A, Massie B, Karpati G 1995 The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants. Gene Ther 2:107-115
    • (1995) Gene Ther , vol.2 , pp. 107-115
    • Huard, J.1    Lochmüller, H.2    Acsadi, G.3    Jani, A.4    Massie, B.5    Karpati, G.6
  • 24
    • 0033607176 scopus 로고    scopus 로고
    • Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
    • Foretz M, Guichard C, Ferre P, Foufelle F 1999 Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci USA 96:12737-12742
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12737-12742
    • Foretz, M.1    Guichard, C.2    Ferre, P.3    Foufelle, F.4
  • 27
    • 0038363836 scopus 로고    scopus 로고
    • Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16
    • Imae M, Fu Z, Yoshida A, Noguchi T, Kato H 2003 Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16. J Mol Endocrinol 30:253-262
    • (2003) J Mol Endocrinol , vol.30 , pp. 253-262
    • Imae, M.1    Fu, Z.2    Yoshida, A.3    Noguchi, T.4    Kato, H.5
  • 28
    • 0028567884 scopus 로고
    • Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus
    • Valera A, Pujol A, Pelegrin M, Bosch F 1994 Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci USA 91:9151-9154
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9151-9154
    • Valera, A.1    Pujol, A.2    Pelegrin, M.3    Bosch, F.4
  • 29
    • 0037324750 scopus 로고    scopus 로고
    • Insulin signaling is required for insulin's direct and indirect action on hepatic glucose production
    • Fisher SJ, Kahn CR 2003 Insulin signaling is required for insulin's direct and indirect action on hepatic glucose production. J Clin Invest 111:463-468
    • (2003) J Clin Invest , vol.111 , pp. 463-468
    • Fisher, S.J.1    Kahn, C.R.2
  • 30
    • 1642464560 scopus 로고    scopus 로고
    • Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: Characterization of phosphorylation- And 14-3-3-dependent and -independent mechanisms
    • Zhao X, Gan L, Pan H, Kan D, Majeski M, Adam SA, Unterman TG 2004 Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms. Biochem J 378:839-849
    • (2004) Biochem J , vol.378 , pp. 839-849
    • Zhao, X.1    Gan, L.2    Pan, H.3    Kan, D.4    Majeski, M.5    Adam, S.A.6    Unterman, T.G.7
  • 31
    • 0344530503 scopus 로고    scopus 로고
    • Insulin inhibition of transcription stimulated by the forkhead protein Foxo1 is not solely due to nuclear exclusion
    • Tsai WC, Bhattacharyya N, Han LY, Hanover JA, Rechler MM 2003 Insulin inhibition of transcription stimulated by the forkhead protein Foxo1 is not solely due to nuclear exclusion. Endocrinology 144:5615-5622
    • (2003) Endocrinology , vol.144 , pp. 5615-5622
    • Tsai, W.C.1    Bhattacharyya, N.2    Han, L.Y.3    Hanover, J.A.4    Rechler, M.M.5
  • 32
    • 0037160050 scopus 로고    scopus 로고
    • Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding
    • Zhang X, Gan L, Pan H, Guo S, He X, Olson ST, Mesecar A, Adam S, Unterman TG 2002 Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding. J Biol Chem 277:45276-45284
    • (2002) J Biol Chem , vol.277 , pp. 45276-45284
    • Zhang, X.1    Gan, L.2    Pan, H.3    Guo, S.4    He, X.5    Olson, S.T.6    Mesecar, A.7    Adam, S.8    Unterman, T.G.9
  • 33
    • 33751547933 scopus 로고    scopus 로고
    • Foxo1 plays a role in mediating the effect of fibrates on diabetic dyslipidemia
    • Altomonte J, Anthony K, Baliga S, Xu J, Dong H 2004 Foxo1 plays a role in mediating the effect of fibrates on diabetic dyslipidemia. Diabetes 53(Suppl 2):A227
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 2
    • Altomonte, J.1    Anthony, K.2    Baliga, S.3    Xu, J.4    Dong, H.5
  • 35
    • 0035957414 scopus 로고    scopus 로고
    • Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes
    • Zhang J, Ou J, Bashmakov Y, Horton JD, Brown MS, Goldstein JL 2001 Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes. Proc Natl Acad Sci USA 98:3756-3761
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3756-3761
    • Zhang, J.1    Ou, J.2    Bashmakov, Y.3    Horton, J.D.4    Brown, M.S.5    Goldstein, J.L.6
  • 38
    • 33748312093 scopus 로고    scopus 로고
    • Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism
    • Matsumoto M, Han S, Kitamura T, Accili D 2006 Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism. J Clin Invest, 116:2464-2472
    • (2006) J Clin Invest , vol.116 , pp. 2464-2472
    • Matsumoto, M.1    Han, S.2    Kitamura, T.3    Accili, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.