메뉴 건너뛰기




Volumn 10, Issue 7, 2015, Pages

Vitamin D antagonises the suppressive effect of inflammatory cytokines on CTLA-4 expression and regulatory function

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; B7 ANTIGEN; CALCITRIOL RECEPTOR; CD86 ANTIGEN; CD86 PROTEIN, HUMAN; CYTOKINE; VITAMIN D;

EID: 84940056402     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131539     Document Type: Article
Times cited : (43)

References (62)
  • 1
    • 0030443168 scopus 로고    scopus 로고
    • Regulation of surface and intracellular expression of CTLA4 on mouse T cells
    • PMID: 8943377
    • Alegre ML, Noel PJ, Eisfelder BJ, Chuang E, Clark MR, Reiner SL, et al. Regulation of surface and intracellular expression of CTLA4 on mouse T cells. J Immunol. 1996; 157(11):4762-70. PMID: 8943377.
    • (1996) J Immunol , vol.157 , Issue.11 , pp. 4762-4770
    • Alegre, M.L.1    Noel, P.J.2    Eisfelder, B.J.3    Chuang, E.4    Clark, M.R.5    Reiner, S.L.6
  • 2
    • 0027282960 scopus 로고
    • Characterization of CTLA-4 structure and expression on human T cells
    • PMID: 8397258
    • Lindsten T, Lee KP, Harris ES, Petryniak B, Craighead N, Reynolds PJ, et al. Characterization of CTLA-4 structure and expression on human T cells. J Immunol. 1993; 151(7):3489-99. PMID: 8397258.
    • (1993) J Immunol , vol.151 , Issue.7 , pp. 3489-3499
    • Lindsten, T.1    Lee, K.P.2    Harris, E.S.3    Petryniak, B.4    Craighead, N.5    Reynolds, P.J.6
  • 3
    • 33746336533 scopus 로고    scopus 로고
    • The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology
    • PMID: 16903911
    • Sansom DM, Walker LS. The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology. Immunological reviews. 2006; 212:131-48. PMID: 16903911.
    • (2006) Immunological Reviews , vol.212 , pp. 131-148
    • Sansom, D.M.1    Walker, L.S.2
  • 4
    • 49649113444 scopus 로고    scopus 로고
    • Acquisition of suppressive function by activated human CD4+
    • PMID: 380
    • Zheng Y, Manzotti CN, Burke F, Dussably L, Qureshi O, Walker LS, et al. Acquisition of suppressive function by activated human CD4+. J Immunol. 2008; 181(3):1683-91. PMID: 380.
    • (2008) J Immunol , vol.181 , Issue.3 , pp. 1683-1691
    • Zheng, Y.1    Manzotti, C.N.2    Burke, F.3    Dussably, L.4    Qureshi, O.5    Walker, L.S.6
  • 5
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • PMID: 309
    • Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity. 1995; 3:541-7. PMID: 309.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 7
    • 84907909000 scopus 로고    scopus 로고
    • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4
    • Epub 2014/09/13. PMID: 25213377
    • Kuehn HS, Ouyang W, Lo B, Deenick EK, Niemela JE, Avery DT, et al. Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4. Science (New York, NY. 2014; 345 (6204):1623-7. Epub 2014/09/13. doi: 10.1126/science.1255904 PMID: 25213377.
    • (2014) Science New York, NY , vol.345 , Issue.6204 , pp. 1623-1627
    • Kuehn, H.S.1    Ouyang, W.2    Lo, B.3    Deenick, E.K.4    Niemela, J.E.5    Avery, D.T.6
  • 8
    • 84938070889 scopus 로고    scopus 로고
    • Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations
    • Epub 2014/10/21. PMID: 25329329
    • Schubert D, Bode C, Kenefeck R, Hou TZ, Wing JB, Kennedy A, et al. Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations. Nature medicine. 2014; 20(12):1410-6. Epub 2014/10/21. doi: 10.1038/nm.3746 PMID: 25329329.
    • (2014) Nature Medicine , vol.20 , Issue.12 , pp. 1410-1416
    • Schubert, D.1    Bode, C.2    Kenefeck, R.3    Hou, T.Z.4    Wing, J.B.5    Kennedy, A.6
  • 9
    • 82255192901 scopus 로고    scopus 로고
    • The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
    • Epub 2011/11/26. PMID: 22116087
    • Walker LS, Sansom DM. The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses. Nature reviews. 2011; 11(12):852-63. Epub 2011/11/26. doi: 10.1038/nri3108 PMID: 22116087.
    • (2011) Nature Reviews , vol.11 , Issue.12 , pp. 852-863
    • Walker, L.S.1    Sansom, D.M.2
  • 10
    • 79954459308 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family
    • Epub 2011/04/15. PMID: 21488898; PubMed Central PMCID: PMC3077803
    • Bour-Jordan H, Esensten JH, Martinez-Llordella M, Penaranda C, Stumpf M, Bluestone JA. Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family. Immunological reviews. 2011; 241(1):180-205. Epub 2011/04/15. doi: 10.1111/j.1600-065X.2011.01011.x PMID: 21488898; PubMed Central PMCID: PMC3077803.
    • (2011) Immunological Reviews , vol.241 , Issue.1 , pp. 180-205
    • Bour-Jordan, H.1    Esensten, J.H.2    Martinez-Llordella, M.3    Penaranda, C.4    Stumpf, M.5    Bluestone, J.A.6
  • 11
    • 38549089084 scopus 로고    scopus 로고
    • The reverse stop-signal model for CTLA4 function
    • Epub 2008/01/26. PMID: 18219311
    • Rudd CE. The reverse stop-signal model for CTLA4 function. Nature reviews. 2008; 8(2):153-60. Epub 2008/01/26. doi: 10.1038/nri2253 PMID: 18219311.
    • (2008) Nature Reviews , vol.8 , Issue.2 , pp. 153-160
    • Rudd, C.E.1
  • 12
    • 0036172220 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength
    • PMID: 11825563
    • Egen JG, Allison JP. Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength. Immunity. 2002; 16(1):23-35. PMID: 11825563.
    • (2002) Immunity , vol.16 , Issue.1 , pp. 23-35
    • Egen, J.G.1    Allison, J.P.2
  • 13
    • 0030176371 scopus 로고    scopus 로고
    • Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement
    • PMID: 8673700
    • Linsley PS, Bradshaw J, Greene J, Peach R, Bennett KL, Mittler RS. Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement. Immunity. 1996; 4(6):535-43. PMID: 8673700.
    • (1996) Immunity , vol.4 , Issue.6 , pp. 535-543
    • Linsley, P.S.1    Bradshaw, J.2    Greene, J.3    Peach, R.4    Bennett, K.L.5    Mittler, R.S.6
  • 14
    • 84858590457 scopus 로고    scopus 로고
    • Constitutive Clathrin-mediated Endocytosis of CTLA-4 Persists during T Cell Activation
    • Epub 2012/01/21. M111.304329 [pii] PMID: 22262842
    • Qureshi OS, Kaur S, Hou TZ, Jeffery LE, Poulter NS, Briggs Z, et al. Constitutive Clathrin-mediated Endocytosis of CTLA-4 Persists during T Cell Activation. J Biol Chem. 2012; 287(12):9429-40. Epub 2012/01/21. M111.304329 [pii] doi: 10.1074/jbc.M111.304329 PMID: 22262842.
    • (2012) J Biol Chem , vol.287 , Issue.12 , pp. 9429-9440
    • Qureshi, O.S.1    Kaur, S.2    Hou, T.Z.3    Jeffery, L.E.4    Poulter, N.S.5    Briggs, Z.6
  • 15
    • 79955529454 scopus 로고    scopus 로고
    • Trans-endocytosis of CD80 and CD86: A molecular basis for the cell-extrinsic function of CTLA-4
    • Epub 2011/04/09. PMID: 21474713; PubMed Central PMCID: PMC3198051
    • Qureshi OS, Zheng Y, Nakamura K, Attridge K, Manzotti C, Schmidt EM, et al. Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science (New York, NY. 2011; 332(6029):600-3. Epub 2011/04/09. doi: 10.1126/science.1202947 PMID: 21474713; PubMed Central PMCID: PMC3198051.
    • (2011) Science New York, NY , vol.332 , Issue.6029 , pp. 600-603
    • Qureshi, O.S.1    Zheng, Y.2    Nakamura, K.3    Attridge, K.4    Manzotti, C.5    Schmidt, E.M.6
  • 16
    • 82955232358 scopus 로고    scopus 로고
    • The many faces of Th17 cells
    • Epub 2011/09/09. PMID: 21899997; PubMed Central PMCID: PMC3232281
    • Peters A, Lee Y, Kuchroo VK. The many faces of Th17 cells. Current opinion in immunology. 2011; 23 (6):702-6. Epub 2011/09/09. doi: 10.1016/j.coi.2011.08.007 PMID: 21899997; PubMed Central PMCID: PMC3232281.
    • (2011) Current Opinion in Immunology , vol.23 , Issue.6 , pp. 702-706
    • Peters, A.1    Lee, Y.2    Kuchroo, V.K.3
  • 17
    • 34247555353 scopus 로고    scopus 로고
    • Differentiation and function of Th17 T cells
    • Epub 2007/04/17. PMID: 17433650
    • Stockinger B, Veldhoen M. Differentiation and function of Th17 T cells. Current opinion in immunology. 2007; 19(3):281-6. Epub 2007/04/17. doi: 10.1016/j.coi.2007.04.005 PMID: 17433650.
    • (2007) Current Opinion in Immunology , vol.19 , Issue.3 , pp. 281-286
    • Stockinger, B.1    Veldhoen, M.2
  • 18
    • 84886710136 scopus 로고    scopus 로고
    • T helper 17 cells in autoimmune liver diseases
    • Epub 2013/11/14. PMID: 24223606; PubMed Central PMCID: PMC3810350
    • Abe M, Hiasa Y, Onji M. T helper 17 cells in autoimmune liver diseases. Clinical & developmental immunology. 2013; 2013:607073. Epub 2013/11/14. doi: 10.1155/2013/607073 PMID: 24223606; PubMed Central PMCID: PMC3810350.
    • (2013) Clinical & Developmental Immunology , vol.2013
    • Abe, M.1    Hiasa, Y.2    Onji, M.3
  • 19
    • 84862695017 scopus 로고    scopus 로고
    • Th17 cells: Biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies
    • Epub 2012/05/30. PMID: 22640807
    • Maddur MS, Miossec P, Kaveri SV, Bayry J. Th17 cells: biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies. The American journal of pathology. 2012; 181(1):8-18. Epub 2012/05/30. doi: 10.1016/j.ajpath.2012.03.044 PMID: 22640807.
    • (2012) The American Journal of Pathology , vol.181 , Issue.1 , pp. 8-18
    • Maddur, M.S.1    Miossec, P.2    Kaveri, S.V.3    Bayry, J.4
  • 20
    • 84867197977 scopus 로고    scopus 로고
    • TH17 cells in autoimmunity and immunodeficiency: Protective or pathogenic?
    • PMID: 22566889
    • Marwaha A, Leung N, McMurchy AN, Levings M. TH17 cells in autoimmunity and immunodeficiency: protective or pathogenic? Frontiers in Immunology. 2012;3. doi: 10.3389/fimmu.2012.00129 PMID: 22566889
    • (2012) Frontiers in Immunology , vol.3
    • Marwaha, A.1    Leung, N.2    McMurchy, A.N.3    Levings, M.4
  • 21
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • PMID: 105
    • Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006; 441(7090):235-8. PMID: 105.
    • (2006) Nature , vol.441 , Issue.7090 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6
  • 22
    • 46749138596 scopus 로고    scopus 로고
    • Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
    • PMID: 366
    • Yang XO, Nurieva R, Martinez GJ, Kang HS, Chung Y, Pappu BP, et al. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity. 2008; 29(1):44-56. PMID: 366. doi: 10.1016/j.immuni.2008.05.007
    • (2008) Immunity , vol.29 , Issue.1 , pp. 44-56
    • Yang, X.O.1    Nurieva, R.2    Martinez, G.J.3    Kang, H.S.4    Chung, Y.5    Pappu, B.P.6
  • 23
    • 44049104564 scopus 로고    scopus 로고
    • The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
    • PMID: 2
    • Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol. 2008; 9(6):641-9. PMID: 2. doi: 10.1038/ni.1610
    • (2008) Nat Immunol , vol.9 , Issue.6 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3
  • 24
    • 44049102724 scopus 로고    scopus 로고
    • A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T (H)-17 responses
    • PMID: 100
    • Volpe E, Servant N, Zollinger R, Bogiatzi SI, Hupe P, Barillot E, et al. A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T (H)-17 responses. Nat Immunol. 2008; 9(6):650-7. PMID: 100. doi: 10.1038/ni.1613
    • (2008) Nat Immunol , vol.9 , Issue.6 , pp. 650-657
    • Volpe, E.1    Servant, N.2    Zollinger, R.3    Bogiatzi, S.I.4    Hupe, P.5    Barillot, E.6
  • 25
    • 84884902641 scopus 로고    scopus 로고
    • Vitamin D in systemic and organ-specific autoimmune diseases
    • Epub 2012/12/15. PMID: 23238772
    • Agmon-Levin N, Theodor E, Segal RM, Shoenfeld Y. Vitamin D in systemic and organ-specific autoimmune diseases. Clinical reviews in allergy & immunology. 2013; 45(2):256-66. Epub 2012/12/15. doi: 10.1007/s12016-012-8342-y PMID: 23238772.
    • (2013) Clinical Reviews in Allergy & Immunology , vol.45 , Issue.2 , pp. 256-266
    • Agmon-Levin, N.1    Theodor, E.2    Segal, R.M.3    Shoenfeld, Y.4
  • 26
    • 84870244915 scopus 로고    scopus 로고
    • Can supplementation with vitamin D reduce the risk or modify the course of autoimmune diseases? A systematic review of the literature
    • Epub 2012/07/11. PMID: 22776787
    • Antico A, Tampoia M, Tozzoli R, Bizzaro N. Can supplementation with vitamin D reduce the risk or modify the course of autoimmune diseases? A systematic review of the literature. Autoimmunity reviews. 2012; 12(2):127-36. Epub 2012/07/11. doi: 10.1016/j.autrev.2012.07.007 PMID: 22776787.
    • (2012) Autoimmunity Reviews , vol.12 , Issue.2 , pp. 127-136
    • Antico, A.1    Tampoia, M.2    Tozzoli, R.3    Bizzaro, N.4
  • 27
    • 84873334895 scopus 로고    scopus 로고
    • Vitamin D deficiency and risk for rheumatic diseases: An update
    • Epub 2013/02/02. PMID: 23370372
    • Gatenby P, Lucas R, Swaminathan A. Vitamin D deficiency and risk for rheumatic diseases: an update. Current opinion in rheumatology. 2013; 25(2):184-91. Epub 2013/02/02. doi: 10.1097/BOR.0b013e32835cfc16 PMID: 23370372.
    • (2013) Current Opinion in Rheumatology , vol.25 , Issue.2 , pp. 184-191
    • Gatenby, P.1    Lucas, R.2    Swaminathan, A.3
  • 28
    • 79955974612 scopus 로고    scopus 로고
    • Does vitamin D affect risk of developing autoimmune disease?: A systematic review
    • Epub 2010/ 11/05. PMID: 21047669; PubMed Central PMCID: PMC3098920
    • Kriegel MA, Manson JE, Costenbader KH. Does vitamin D affect risk of developing autoimmune disease?: a systematic review. Seminars in arthritis and rheumatism. 2011; 40(6):512-31e8. Epub 2010/ 11/05. doi: 10.1016/j.semarthrit.2010.07.009 PMID: 21047669; PubMed Central PMCID: PMC3098920.
    • (2011) Seminars in Arthritis and Rheumatism , vol.40 , Issue.6 , pp. 512-31e8
    • Kriegel, M.A.1    Manson, J.E.2    Costenbader, K.H.3
  • 29
    • 84884907511 scopus 로고    scopus 로고
    • The implication of vitamin D and autoimmunity: A comprehensive review
    • Epub 2013/01/30. PMID: 23359064
    • Yang CY, Leung PS, Adamopoulos IE, Gershwin ME. The implication of vitamin D and autoimmunity: a comprehensive review. Clinical reviews in allergy & immunology. 2013; 45(2):217-26. Epub 2013/01/30. doi: 10.1007/s12016-013-8361-3 PMID: 23359064.
    • (2013) Clinical Reviews in Allergy & Immunology , vol.45 , Issue.2 , pp. 217-226
    • Yang, C.Y.1    Leung, P.S.2    Adamopoulos, I.E.3    Gershwin, M.E.4
  • 30
    • 84861575039 scopus 로고    scopus 로고
    • Vitamin D, multiple sclerosis and inflammatory bowel disease
    • Epub 2011/11/17. PMID: 22085500; PubMed Central PMCID: PMC3374859
    • Cantorna MT. Vitamin D, multiple sclerosis and inflammatory bowel disease. Arch Biochem Biophys. 2012; 523(1):103-6. Epub 2011/11/17. doi: 10.1016/j.abb.2011.11.001 PMID: 22085500; PubMed Central PMCID: PMC3374859.
    • (2012) Arch Biochem Biophys , vol.523 , Issue.1 , pp. 103-106
    • Cantorna, M.T.1
  • 31
    • 77958605267 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect against experimental autoimmune encephalomyelitis
    • Epub 2010/10/05. PMID: 20886077; PubMed Central PMCID: PMC2944871
    • Chang JH, Cha HR, Lee DS, Seo KY, Kweon MN. 1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect against experimental autoimmune encephalomyelitis. PLoS One. 2010; 5(9):e12925. Epub 2010/10/05. doi: 10.1371/journal.pone.0012925 PMID: 20886077; PubMed Central PMCID: PMC2944871.
    • (2010) PLoS One , vol.5 , Issue.9
    • Chang, J.H.1    Cha, H.R.2    Lee, D.S.3    Seo, K.Y.4    Kweon, M.N.5
  • 32
    • 0028357305 scopus 로고
    • Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3
    • PMID: 434
    • Mathieu C, Waer M, Laureys J, Rutgeerts O, Bouillon R. Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3. Diabetologia. 1994; 37(6):552-8. PMID: 434.
    • (1994) Diabetologia , vol.37 , Issue.6 , pp. 552-558
    • Mathieu, C.1    Waer, M.2    Laureys, J.3    Rutgeerts, O.4    Bouillon, R.5
  • 33
    • 79951782445 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis
    • Epub 2011/02/03. PMID: 21287548
    • Mayne CG, Spanier JA, Relland LM, Williams CB, Hayes CE. 1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis. Eur J Immunol. 2011; 41(3):822-32. Epub 2011/02/03. doi: 10.1002/eji.201040632 PMID: 21287548.
    • (2011) Eur J Immunol , vol.41 , Issue.3 , pp. 822-832
    • Mayne, C.G.1    Spanier, J.A.2    Relland, L.M.3    Williams, C.B.4    Hayes, C.E.5
  • 34
    • 77951253745 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3
    • Epub 2009/10/22. PMID: 19843932; PubMed Central PMCID: PMC2810518
    • Jeffery LE, Burke F, Mura M, Zheng Y, Qureshi OS, Hewison M, et al. 1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3. J Immunol. 2009; 183(9):5458-67. Epub 2009/10/22. doi: 10.4049/jimmunol.0803217 PMID: 19843932; PubMed Central PMCID: PMC2810518.
    • (2009) J Immunol , vol.183 , Issue.9 , pp. 5458-5467
    • Jeffery, L.E.1    Burke, F.2    Mura, M.3    Zheng, Y.4    Qureshi, O.S.5    Hewison, M.6
  • 35
    • 8544221865 scopus 로고    scopus 로고
    • Interferon-gamma differentially regulates CD80 (B7-1) and CD86 (B7-2/B70) expression on human Langerhans cells
    • Epub 1997/06/01. PMID: 9217813
    • Yokozeki H, Katayama I, Ohki O, Arimura M, Takayama K, Matsunaga T, et al. Interferon-gamma differentially regulates CD80 (B7-1) and CD86 (B7-2/B70) expression on human Langerhans cells. The British journal of dermatology. 1997; 136(6):831-7. Epub 1997/06/01. PMID: 9217813.
    • (1997) The British Journal of Dermatology , vol.136 , Issue.6 , pp. 831-837
    • Yokozeki, H.1    Katayama, I.2    Ohki, O.3    Arimura, M.4    Takayama, K.5    Matsunaga, T.6
  • 36
    • 3343025089 scopus 로고    scopus 로고
    • Interferon-gamma Added During Bacillus Calmette-Guerin Induced Dendritic Cell Maturation Stimulates Potent Th1 Immune Responses
    • Epub 2003/10/29. PMID: 14580262; PubMed Central PMCID: PMC239912
    • Shankar G, Pestano LA, Bosch ML. Interferon-gamma Added During Bacillus Calmette-Guerin Induced Dendritic Cell Maturation Stimulates Potent Th1 Immune Responses. Journal of translational medicine. 2003; 1(1):7. Epub 2003/10/29. doi: 10.1186/1479-5876-1-7 PMID: 14580262; PubMed Central PMCID: PMC239912.
    • (2003) Journal of Translational Medicine , vol.1 , Issue.1 , pp. 7
    • Shankar, G.1    Pestano, L.A.2    Bosch, M.L.3
  • 37
    • 0029968484 scopus 로고    scopus 로고
    • Interferon-gamma and interleukin-10 inhibit antigen presentation by Langerhans cells for T helper type 1 cells by suppressing their CD80 (B7-1) expression
    • Epub 1996/03/01. PMID: 8605933
    • Ozawa H, Aiba S, Nakagawa, Tagami H. Interferon-gamma and interleukin-10 inhibit antigen presentation by Langerhans cells for T helper type 1 cells by suppressing their CD80 (B7-1) expression. Eur J Immunol. 1996; 26(3):648-52. Epub 1996/03/01. doi: 10.1002/eji.1830260321 PMID: 8605933.
    • (1996) Eur J Immunol , vol.26 , Issue.3 , pp. 648-652
    • Ozawa, H.1    Aiba, S.2    Nakagawa3    Tagami, H.4
  • 38
    • 0036669785 scopus 로고    scopus 로고
    • The interaction properties of costimulatory molecules revisited
    • Epub 2002/08/28. PMID: 12196291
    • Collins AV, Brodie DW, Gilbert RJ, Iaboni A, Manso-Sancho R, Walse B, et al. The interaction properties of costimulatory molecules revisited. Immunity. 2002; 17(2):201-10. Epub 2002/08/28. PMID: 12196291.
    • (2002) Immunity , vol.17 , Issue.2 , pp. 201-210
    • Collins, A.V.1    Brodie, D.W.2    Gilbert, R.J.3    Iaboni, A.4    Manso-Sancho, R.5    Walse, B.6
  • 39
    • 0042389785 scopus 로고    scopus 로고
    • T cell anergy
    • Epub 2002/12/10. PMID: 12471050
    • Schwartz RH. T cell anergy. Annual review of immunology. 2003; 21:305-34. Epub 2002/12/10. doi: 10.1146/annurev.immunol.21.120601.141110 PMID: 12471050.
    • (2003) Annual Review of Immunology , vol.21 , pp. 305-334
    • Schwartz, R.H.1
  • 40
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
    • PMID: 10899916
    • Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med. 2000; 192(2):295-302. PMID: 10899916.
    • (2000) J Exp Med , vol.192 , Issue.2 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 41
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • PMID: 375
    • Takahashi T, Tagami T, Yamazaki S, Uede T, Shimizu J, Sakaguchi N, et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med. 2000; 192(2):303-10. PMID: 375.
    • (2000) J Exp Med , vol.192 , Issue.2 , pp. 303-310
    • Takahashi, T.1    Tagami, T.2    Yamazaki, S.3    Uede, T.4    Shimizu, J.5    Sakaguchi, N.6
  • 43
    • 84864128521 scopus 로고    scopus 로고
    • Cutting edge: CTLA-4 on effector T cells inhibits in trans
    • Epub 2012/07/04. PMID: 22753941
    • Corse E, Allison JP. Cutting edge: CTLA-4 on effector T cells inhibits in trans. J Immunol. 2012; 189 (3):1123-7. Epub 2012/07/04. doi: 10.4049/jimmunol.1200695 PMID: 22753941.
    • (2012) J Immunol , vol.189 , Issue.3 , pp. 1123-1127
    • Corse, E.1    Allison, J.P.2
  • 44
    • 84864123005 scopus 로고    scopus 로고
    • Cutting edge: Cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells
    • Epub 2012/07/04. PMID: 22753931; PubMed Central PMCID: PMC3442233
    • Wang CJ, Kenefeck R, Wardzinski L, Attridge K, Manzotti C, Schmidt EM, et al. Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells. J Immunol. 2012; 189 (3):1118-22. Epub 2012/07/04. doi: 10.4049/jimmunol.1200972 PMID: 22753931; PubMed Central PMCID: PMC3442233.
    • (2012) J Immunol , vol.189 , Issue.3 , pp. 1118-1122
    • Wang, C.J.1    Kenefeck, R.2    Wardzinski, L.3    Attridge, K.4    Manzotti, C.5    Schmidt, E.M.6
  • 45
    • 68149155982 scopus 로고    scopus 로고
    • Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
    • Epub 2009/07/08. PMID: 19581407; PubMed Central PMCID: PMC2722174
    • Peggs KS, Quezada SA, Chambers CA, Korman AJ, Allison JP. Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J Exp Med. 2009; 206(8):1717-25. Epub 2009/07/08. doi: 10.1084/jem.20082492 PMID: 19581407; PubMed Central PMCID: PMC2722174.
    • (2009) J Exp Med , vol.206 , Issue.8 , pp. 1717-1725
    • Peggs, K.S.1    Quezada, S.A.2    Chambers, C.A.3    Korman, A.J.4    Allison, J.P.5
  • 46
    • 76549084610 scopus 로고    scopus 로고
    • Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity
    • Epub 2010/01/19. PMID: 20080649; PubMed Central PMCID: PMC2824392
    • Jain N, Nguyen H, Chambers C, Kang J. Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(4):1524-8. Epub 2010/01/19. doi: 10.1073/pnas.0910341107 PMID: 20080649; PubMed Central PMCID: PMC2824392.
    • (2010) Proceedings of the National Academy of Sciences of the United States of America , vol.107 , Issue.4 , pp. 1524-1528
    • Jain, N.1    Nguyen, H.2    Chambers, C.3    Kang, J.4
  • 48
    • 84878922773 scopus 로고    scopus 로고
    • Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction
    • Epub 2013/06/19. PMID: 23776439; PubMed Central PMCID: PMC3679128
    • Liu X, Gao N, Li M, Xu D, Hou Y, Wang Q, et al. Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction. PLoS One. 2013; 8(6):e64531. Epub 2013/06/19. doi: 10.1371/journal.pone.0064531 PMID: 23776439; PubMed Central PMCID: PMC3679128.
    • (2013) PLoS One , vol.8 , Issue.6
    • Liu, X.1    Gao, N.2    Li, M.3    Xu, D.4    Hou, Y.5    Wang, Q.6
  • 49
    • 68249100526 scopus 로고    scopus 로고
    • Diminished expression of ICOS, GITR and CTLA-4 at the mRNA level in T regulatory cells of children with newly diagnosed type 1 diabetes
    • PMID: 19547759
    • Luczynski W, Wawrusiewicz-Kurylonek N, Stasiak-Barmuta A, Urban R, Ilendo E, Urban M, et al. Diminished expression of ICOS, GITR and CTLA-4 at the mRNA level in T regulatory cells of children with newly diagnosed type 1 diabetes. Acta biochimica Polonica. 2009; 56(2):361-70. PMID: 19547759.
    • (2009) Acta Biochimica Polonica , vol.56 , Issue.2 , pp. 361-370
    • Luczynski, W.1    Wawrusiewicz-Kurylonek, N.2    Stasiak-Barmuta, A.3    Urban, R.4    Ilendo, E.5    Urban, M.6
  • 50
    • 0142152430 scopus 로고    scopus 로고
    • Regulation of 25-hydroxyvitamin D3-1 alpha-hydroxylase and production of 1 alpha,25-dihydroxyvitamin D3 by human dendritic cells
    • PMID: 444
    • Fritsche J, Mondal K, Ehrnsperger A, Andreesen R, Kreutz M. Regulation of 25-hydroxyvitamin D3-1 alpha-hydroxylase and production of 1 alpha,25-dihydroxyvitamin D3 by human dendritic cells Blood. 2003; 102(9):3314-6. PMID: 444.
    • (2003) Blood , vol.102 , Issue.9 , pp. 3314-3316
    • Fritsche, J.1    Mondal, K.2    Ehrnsperger, A.3    Andreesen, R.4    Kreutz, M.5
  • 51
    • 84869815306 scopus 로고    scopus 로고
    • Availability of 25-Hydroxyvitamin D3 to APCs Controls the Balance between Regulatory and Inflammatory T Cell Responses
    • Epub 2012/10/23. PMID: 23087405; PubMed Central PMCID: PMC3504609
    • Jeffery LE, Wood AM, Qureshi OS, Hou TZ, Gardner D, Briggs Z, et al. Availability of 25-Hydroxyvitamin D3 to APCs Controls the Balance between Regulatory and Inflammatory T Cell Responses. J Immunol. 2012; 189(11):5155-64. Epub 2012/10/23. doi: 10.4049/jimmunol.1200786 PMID: 23087405; PubMed Central PMCID: PMC3504609.
    • (2012) J Immunol , vol.189 , Issue.11 , pp. 5155-5164
    • Jeffery, L.E.1    Wood, A.M.2    Qureshi, O.S.3    Hou, T.Z.4    Gardner, D.5    Briggs, Z.6
  • 52
    • 58149182886 scopus 로고    scopus 로고
    • IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway
    • Epub 2008/11/05. doi: 181/10/7115 [pii]. PMID: 18981132; PubMed Central PMCID: PMC2678236
    • Krutzik SR, Hewison M, Liu PT, Robles JA, Stenger S, Adams JS, et al. IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway. J Immunol. 2008; 181 (10):7115-20. Epub 2008/11/05. doi: 181/10/7115 [pii]. PMID: 18981132; PubMed Central PMCID: PMC2678236.
    • (2008) J Immunol , vol.181 , Issue.10 , pp. 7115-7120
    • Krutzik, S.R.1    Hewison, M.2    Liu, P.T.3    Robles, J.A.4    Stenger, S.5    Adams, J.S.6
  • 53
    • 33645224419 scopus 로고    scopus 로고
    • Toll-like receptor triggering of a vitamin D- mediated human antimicrobial response
    • PMID: 358
    • Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, et al. Toll-like receptor triggering of a vitamin D- mediated human antimicrobial response Science (New York, NY. 2006; 311(5768):1770-3. PMID: 358.
    • (2006) Science New York, NY , vol.311 , Issue.5768 , pp. 1770-1773
    • Liu, P.T.1    Stenger, S.2    Li, H.3    Wenzel, L.4    Tan, B.H.5    Krutzik, S.R.6
  • 54
    • 0037302966 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases
    • PMID: 382
    • Adorini L, Penna G, Giarratana N, Uskokovic M. Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases. JCell Biochem. 2003; 88(2):227-33. PMID: 382.
    • (2003) JCell Biochem , vol.88 , Issue.2 , pp. 227-233
    • Adorini, L.1    Penna, G.2    Giarratana, N.3    Uskokovic, M.4
  • 55
    • 0343238444 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D(3) inhibits dendritic cell differentiation and maturation in vitro
    • PMID: 363
    • Berer A, Stockl J, Majdic O, Wagner T, Kollars M, Lechner K, et al. 1,25-Dihydroxyvitamin D(3) inhibits dendritic cell differentiation and maturation in vitro. ExpHematol. 2000; 28(5):575-83. PMID: 363.
    • (2000) ExpHematol , vol.28 , Issue.5 , pp. 575-583
    • Berer, A.1    Stockl, J.2    Majdic, O.3    Wagner, T.4    Kollars, M.5    Lechner, K.6
  • 56
    • 0034161714 scopus 로고    scopus 로고
    • 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
    • PMID: 347
    • Penna G, Adorini L. 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol. 2000; 164 (5):2405-11. PMID: 347.
    • (2000) J Immunol , vol.164 , Issue.5 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 57
    • 33846301634 scopus 로고    scopus 로고
    • Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes
    • Epub 2007/01/02. PMID: 17197413; PubMed Central PMCID: PMC1766426
    • Butty V, Roy M, Sabeti P, Besse W, Benoist C, Mathis D. Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(2):570-5. Epub 2007/01/02. doi: 10.1073/pnas.0610124104 PMID: 17197413; PubMed Central PMCID: PMC1766426.
    • (2007) Proceedings of the National Academy of Sciences of the United States of America , vol.104 , Issue.2 , pp. 570-575
    • Butty, V.1    Roy, M.2    Sabeti, P.3    Besse, W.4    Benoist, C.5    Mathis, D.6
  • 58
    • 80054115387 scopus 로고    scopus 로고
    • CTLA4 gene variants in autoimmunity and cancer: A comparative review
    • Epub 2011/09/21. doi: IJIv8i3A1 PMID: 21931200
    • Ghaderi A. CTLA4 gene variants in autoimmunity and cancer: a comparative review. Iranian journal of immunology: IJI. 2011; 8(3):127-49. Epub 2011/09/21. doi: IJIv8i3A1 PMID: 21931200.
    • (2011) Iranian Journal of Immunology: IJI , vol.8 , Issue.3 , pp. 127-149
    • Ghaderi, A.1
  • 59
    • 16244369437 scopus 로고    scopus 로고
    • CTLA4 gene polymorphism and autoimmunity
    • Epub 2005/03/26. PMID: 15790353
    • Gough SC, Walker LS, Sansom DM. CTLA4 gene polymorphism and autoimmunity. Immunological reviews. 2005; 204:102-15. Epub 2005/03/26. doi: 10.1111/j.0105-2896.2005.00249.x PMID: 15790353.
    • (2005) Immunological Reviews , vol.204 , pp. 102-115
    • Gough, S.C.1    Walker, L.S.2    Sansom, D.M.3
  • 60
    • 17144378972 scopus 로고    scopus 로고
    • CTLA-4 polymorphisms and systemic lupus erythematosus (SLE): A meta-analysis
    • Epub 2005/02/03. PMID: 15688186
    • Lee YH, Harley JB, Nath SK. CTLA-4 polymorphisms and systemic lupus erythematosus (SLE): a meta-analysis. Human genetics. 2005; 116(5):361-7. Epub 2005/02/03. doi: 10.1007/s00439-004-1244-1 PMID: 15688186.
    • (2005) Human Genetics , vol.116 , Issue.5 , pp. 361-367
    • Lee, Y.H.1    Harley, J.B.2    Nath, S.K.3
  • 61
    • 84862687598 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte associated antigen-4 gene polymorphisms and primary biliary cirrhosis: A systematic review
    • Epub 2012/03/15. PMID: 22414241
    • Li M, Zheng H, Li T, Gao P, Zhang XL, Liu DW. Cytotoxic T-lymphocyte associated antigen-4 gene polymorphisms and primary biliary cirrhosis: a systematic review. Journal of gastroenterology and hepatology. 2012; 27(7):1159-66. Epub 2012/03/15. doi: 10.1111/j.1440-1746.2012.07118.x PMID: 22414241.
    • (2012) Journal of Gastroenterology and Hepatology , vol.27 , Issue.7 , pp. 1159-1166
    • Li, M.1    Zheng, H.2    Li, T.3    Gao, P.4    Zhang, X.L.5    Liu, D.W.6
  • 62
    • 77956885532 scopus 로고    scopus 로고
    • A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution
    • Epub 2010/08/26. PMID: 20736230; PubMed Central PMCID: PMC2945184
    • Ramagopalan SV, Heger A, Berlanga AJ, Maugeri NJ, Lincoln MR, Burrell A, et al. A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. Genome Res. 2010; 20(10):1352-60. Epub 2010/08/26. doi: 10.1101/gr.107920.110 PMID: 20736230; PubMed Central PMCID: PMC2945184.
    • (2010) Genome Res , vol.20 , Issue.10 , pp. 1352-1360
    • Ramagopalan, S.V.1    Heger, A.2    Berlanga, A.J.3    Maugeri, N.J.4    Lincoln, M.R.5    Burrell, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.