Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 2, 2007, Pages 570-575

  Butty, Vincent ^a,b   Roy, Matt ^a,b   Sabeti, Pardis ^c   Besse, Whitney ^a,b   Benoist, Christophe ^a,b,d   Mathis, Diane ^a,b,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD UNIVERSITY   (United States)

^d JOSLIN DIABETES CENTER   (United States)

Author keywords

Autoimmunity; Linkage disequilibrium; T cell costimulation

Indexed keywords

CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DNA; INDUCIBLE T LYMPHOCYTE COSTIMULATOR; UNCLASSIFIED DRUG;

ALLELISM; ARTICLE; AUTOIMMUNITY; EVOLUTIONARY ADAPTATION; GENE ACTIVITY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; HAPLOTYPE; HUMAN; IMMUNE RESPONSE; MIGRATION; POPULATION DIFFERENTIATION; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, DIFFERENTIATION; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; AUTOIMMUNITY; CHROMOSOMES, HUMAN, PAIR 2; ETHNIC GROUPS; GENETICS, POPULATION; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; LYMPHOCYTE ACTIVATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); T-LYMPHOCYTES; VARIATION (GENETICS);

EID: 33846301634     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0610124104     Document Type: Article

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