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Volumn 3, Issue 4, 2014, Pages 400-411

Gene-Lifestyle Interactions in Complex Diseases: Design and Description of the GLACIER and VIKING Studies

Author keywords

Biobank; Complex disease; Genealogy; Genetics; Lifestyle; Scandinavia

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 84940008851     PISSN: None     EISSN: 21613311     Source Type: Journal    
DOI: 10.1007/s13668-014-0100-8     Document Type: Review
Times cited : (15)

References (88)
  • 1
    • 84901387060 scopus 로고    scopus 로고
    • Langenberg C Sharp SJ, Franks PW, Scott RA, Deloukas P, Forouhi NG et al. 2014;11(5). This paper describes the largest study of gene-lifestyle interactions in incident type 2 diabetes to date. The study found that genetic effects on diabetes are greater at a younger age and in leaner participants. No evidence of interaction with Mediterranean diet or physical activity were observed
    • Langenberg C Sharp SJ, Franks PW, Scott RA, Deloukas P, Forouhi NG et al. Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study. PLoS Med. 2014;11(5). This paper describes the largest study of gene-lifestyle interactions in incident type 2 diabetes to date. The study found that genetic effects on diabetes are greater at a younger age and in leaner participants. No evidence of interaction with Mediterranean diet or physical activity were observed.
    • Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study. PLoS Me
  • 2
    • 84885011484 scopus 로고    scopus 로고
    • Gene x environment interactions in obesity: the state of the evidence
    • PID: 24081226
    • Ahmad S, Varga TV, Franks PW. Gene x environment interactions in obesity: the state of the evidence. Hum Hered. 2013;75(2–4):106–15.
    • (2013) Hum Here , vol.75 , Issue.2-4 , pp. 106-115
    • Ahmad, S.1    Varga, T.V.2    Franks, P.W.3
  • 4
    • 0008912907 scopus 로고
    • Effect of a phenylalanine-restricted diet on patients with phenylketonuria; clinical observations in three cases
    • COI: 1:CAS:528:DyaG28XnvVOrtQ%3D%3D, PID: 13345635
    • Horner FA, Streamer CW. Effect of a phenylalanine-restricted diet on patients with phenylketonuria; clinical observations in three cases. J Am Med Assoc. 1956;161(17):1628–30.
    • (1956) J Am Med Asso , vol.161 , Issue.17 , pp. 1628-1630
    • Horner, F.A.1    Streamer, C.W.2
  • 5
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 2004;350(21):2129–39.
    • (2004) N Engl J Me , vol.350 , Issue.21 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5    Brannigan, B.W.6
  • 7
    • 84872568730 scopus 로고    scopus 로고
    • The heritability of human disease: estimation, uses and abuses
    • COI: 1:CAS:528:DC%2BC3sXptlKktw%3D%3D, PID: 23329114, This paper outlines appropriate ways of interpreting heritability estimates, and explains how heritability estimates are frequently misinterpreted
    • Tenesa A, Haley CS. The heritability of human disease: estimation, uses and abuses. Nat Rev Genet. 2013;14(2):139–49. This paper outlines appropriate ways of interpreting heritability estimates, and explains how heritability estimates are frequently misinterpreted.
    • (2013) Nat Rev Gene , vol.14 , Issue.2 , pp. 139-149
    • Tenesa, A.1    Haley, C.S.2
  • 8
    • 84891818467 scopus 로고    scopus 로고
    • Pozzilli P.  Is glucose control important for prevention of cardiovascular disease in diabetes?
    • Mannucci E, Dicembrini I, Lauria A, Pozzilli P. Is glucose control important for prevention of cardiovascular disease in diabetes? Diabetes Care. 2013;36 Suppl 2:S259–63.
    • Diabetes Care. 2013;36 Supp , vol.2 , pp. S259-S263
    • Mannucci, E.1    Dicembrini, I.2    Lauria, A.3
  • 10
    • 84875365096 scopus 로고    scopus 로고
    • Intracerebral propagation of Alzheimer's disease: strengthening evidence of a herpes simplex virus etiology
    • Ball MJ, Lukiw WJ, Kammerman EM, Hill JM. Intracerebral propagation of Alzheimer's disease: strengthening evidence of a herpes simplex virus etiology. Alzheimers Dement. 2013;9(2):169–75.
    • (2013) Alzheimers Demen , vol.9 , Issue.2 , pp. 169-175
    • Ball, M.J.1    Lukiw, W.J.2    Kammerman, E.M.3    Hill, J.M.4
  • 11
    • 0034619486 scopus 로고    scopus 로고
    • Chlamydia pneumoniae, herpes simplex virus type 1, and cytomegalovirus and incident myocardial infarction and coronary heart disease death in older adults : the Cardiovascular Health Study
    • Siscovick DS, Schwartz SM, Corey L, Grayston JT, Ashley R, Wang SP et al. Chlamydia pneumoniae, herpes simplex virus type 1, and cytomegalovirus and incident myocardial infarction and coronary heart disease death in older adults: the Cardiovascular Health Study. Circulation. 2000;102(19):2335–40.
    • (2000) Circulatio , vol.102 , Issue.19 , pp. 2335-2340
    • Siscovick, D.S.1    Schwartz, S.M.2    Corey, L.3    Grayston, J.T.4    Ashley, R.5    Wang, S.P.6
  • 12
    • 67650899270 scopus 로고    scopus 로고
    • Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect
    • Caselli RJ, Dueck AC, Osborne D, Sabbagh MN, Connor DJ, Ahern GL et al. Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect. N Engl J Med. 2009;361(3):255–63.
    • (2009) N Engl J Me , vol.361 , Issue.3 , pp. 255-263
    • Caselli, R.J.1    Dueck, A.C.2    Osborne, D.3    Sabbagh, M.N.4    Connor, D.J.5    Ahern, G.L.6
  • 13
    • 84887099827 scopus 로고    scopus 로고
    • Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S et al. Discovery and refinement of loci associated with lipid levels
    • Global Lipids Genetics Consortium, Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S et al. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013;45(11):1274–83.
    • (2013) Nat Gene , vol.45 , Issue.11 , pp. 1274-1283
  • 14
    • 70350231601 scopus 로고    scopus 로고
    • Apolipoprotein E/C1 locus variants modify renal cell carcinoma risk
    • Moore LE, Brennan P, Karami S, Menashe I, Berndt SI, Dong LM et al. Apolipoprotein E/C1 locus variants modify renal cell carcinoma risk. Cancer Res. 2009;69(20):8001–8.
    • (2009) Cancer Re , vol.69 , Issue.20 , pp. 8001-8008
    • Moore, L.E.1    Brennan, P.2    Karami, S.3    Menashe, I.4    Berndt, S.I.5    Dong, L.M.6
  • 15
    • 70349567378 scopus 로고    scopus 로고
    • Fat targets for skeletal health
    • PID: 19468288
    • Kawai M, Devlin MJ, Rosen CJ. Fat targets for skeletal health. Nat Rev Rheumatol. 2009;5(7):365–72.
    • (2009) Nat Rev Rheumato , vol.5 , Issue.7 , pp. 365-372
    • Kawai, M.1    Devlin, M.J.2    Rosen, C.J.3
  • 16
    • 78650417743 scopus 로고    scopus 로고
    • Osteoblast function in myeloma
    • PID: 20601285
    • Roodman GD. Osteoblast function in myeloma. Bone. 2011;48(1):135–40.
    • (2011) Bon , vol.48 , Issue.1 , pp. 135-140
    • Roodman, G.D.1
  • 17
    • 65449115666 scopus 로고    scopus 로고
    • Osteopontin: a multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification
    • COI: 1:CAS:528:DC%2BC3cXhtFKgu7zN, PID: 19361352
    • Cho HJ, Cho HJ, Kim HS. Osteopontin: a multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification. Curr Atheroscler Rep. 2009;11(3):206–13.
    • (2009) Curr Atheroscler Re , vol.11 , Issue.3 , pp. 206-213
    • Cho, H.J.1    Cho, H.J.2    Kim, H.S.3
  • 18
    • 84894455706 scopus 로고    scopus 로고
    • A comparison of hip fracture incidence rates among elderly in Sweden by latitude and sunlight exposure
    • Nilson F, Moniruzzaman S, Andersson R. A comparison of hip fracture incidence rates among elderly in Sweden by latitude and sunlight exposure. Scand J Public Health, 2013.
    • (2013) Scand J Public Healt
    • Nilson, F.1    Moniruzzaman, S.2    Andersson, R.3
  • 19
    • 84880200953 scopus 로고    scopus 로고
    • Vitamin D for health: a global perspective
    • COI: 1:CAS:528:DC%2BC3sXpvVyku7c%3D, PID: 23790560
    • Hossein-nezhad A, Holick MF. Vitamin D for health: a global perspective. Mayo Clin Proc. 2013;88(7):720–55.
    • (2013) Mayo Clin Pro , vol.88 , Issue.7 , pp. 720-755
    • Hossein-nezhad, A.1    Holick, M.F.2
  • 21
    • 79959387975 scopus 로고    scopus 로고
    • Vitamin D and prevention of cardiovascular disease and diabetes: why the evidence falls short
    • COI: 1:CAS:528:DC%2BC3MXotVantLY%3D, PID: 21693745
    • Shapses SA, Manson JE. Vitamin D and prevention of cardiovascular disease and diabetes: why the evidence falls short. JAMA. 2011;305(24):2565–6.
    • (2011) JAM , vol.305 , Issue.24 , pp. 2565-2566
    • Shapses, S.A.1    Manson, J.E.2
  • 22
    • 84872801071 scopus 로고    scopus 로고
    • Borena Wet al.  Total serum cholesterol and cancer incidence in the Metabolic syndrome and Cancer Project (Me-Can)
    • Strohmaier S, Edlinger M, Manjer J, Stocks T, Bjorge T, Borena W et al. Total serum cholesterol and cancer incidence in the Metabolic syndrome and Cancer Project (Me-Can). PLoS One. 2013;8(1):e54242.
    • (2013) PLoS On , vol.8 , Issue.1 , pp. e54242
    • Strohmaier, S.1    Edlinger, M.2    Manjer, J.3    Stocks, T.4    Bjorge, T.5
  • 23
    • 84859616958 scopus 로고    scopus 로고
    • Metabolic risk factors and cervical cancer in the metabolic syndrome and cancer project (Me-Can)
    • Ulmer H, Bjorge T, Concin H, Lukanova A, Manjer J, Hallmans G et al. Metabolic risk factors and cervical cancer in the metabolic syndrome and cancer project (Me-Can). Gynecol Oncol. 2012;125(2):330–5.
    • (2012) Gynecol Onco , vol.125 , Issue.2 , pp. 330-335
    • Ulmer, H.1    Bjorge, T.2    Concin, H.3    Lukanova, A.4    Manjer, J.5    Hallmans, G.6
  • 24
    • 84874570151 scopus 로고    scopus 로고
    • Metabolic factors associated with risk of renal cell carcinoma
    • Haggstrom C, Rapp K, Stocks T, Manjer J, Bjorge T, Ulmer H et al. Metabolic factors associated with risk of renal cell carcinoma. PLoS One. 2013;8(2):e57475.
    • (2013) PLoS On , vol.8 , Issue.2 , pp. e57475
    • Haggstrom, C.1    Rapp, K.2    Stocks, T.3    Manjer, J.4    Bjorge, T.5    Ulmer, H.6
  • 25
    • 84871776513 scopus 로고    scopus 로고
    • Prospective cohort study of metabolic risk factors and gastric adenocarcinoma risk in the Metabolic Syndrome and Cancer Project (Me-Can)
    • Lindkvist B, Almquist M, Bjorge T, Stocks T, Borena W, Johansen D et al. Prospective cohort study of metabolic risk factors and gastric adenocarcinoma risk in the Metabolic Syndrome and Cancer Project (Me-Can). Cancer Causes Control. 2013;24(1):107–16.
    • (2013) Cancer Causes Contro , vol.24 , Issue.1 , pp. 107-116
    • Lindkvist, B.1    Almquist, M.2    Bjorge, T.3    Stocks, T.4    Borena, W.5    Johansen, D.6
  • 26
    • 84870716925 scopus 로고    scopus 로고
    • Haggstrom C, Stocks T, Ulmert D, Bjorge T, Ulmer H, Hallmans G et al. Prospective study on metabolic factors and risk of prostate cancer. Cancer. 2012;118(24):6199–206. This study describes observational analyses linking features of the metabolic syndrome and prostate cancer in European adults. The study includes a cohort from the Northern Sweden Biobank, where the GLACIER and VIKING Studies are set.
    • Prospective study on metabolic factors and risk of prostate cancer. Cancer
  • 27
    • 84867336658 scopus 로고    scopus 로고
    • Metabolic factors and blood cancers among 578,000 adults in the metabolic syndrome and cancer project (Me-Can)
    • Nagel G, Stocks T, Spath D, Hjartaker A, Lindkvist B, Hallmans G et al. Metabolic factors and blood cancers among 578,000 adults in the metabolic syndrome and cancer project (Me-Can). Ann Hematol. 2012;91(10):1519–31.
    • (2012) Ann Hemato , vol.91 , Issue.10 , pp. 1519-1531
    • Nagel, G.1    Stocks, T.2    Spath, D.3    Hjartaker, A.4    Lindkvist, B.5    Hallmans, G.6
  • 28
    • 84858698428 scopus 로고    scopus 로고
    • Blood pressure and risk of cancer incidence and mortality in the Metabolic Syndrome and Cancer Project
    • Stocks T, Van Hemelrijck M, Manjer J, Bjorge T, Ulmer H, Hallmans G et al. Blood pressure and risk of cancer incidence and mortality in the Metabolic Syndrome and Cancer Project. Hypertension. 2012;59(4):802–10.
    • (2012) Hypertensio , vol.59 , Issue.4 , pp. 802-810
    • Stocks, T.1    Van Hemelrijck, M.2    Manjer, J.3    Bjorge, T.4    Ulmer, H.5    Hallmans, G.6
  • 29
    • 84866752008 scopus 로고    scopus 로고
    • Why are diabetics at reduced risk for prostate cancer? A review of the epidemiologic evidence
    • PID: 23021557
    • Pierce BL. Why are diabetics at reduced risk for prostate cancer? A review of the epidemiologic evidence. Urol Oncol. 2012;30(5):735–43.
    • (2012) Urol Onco , vol.30 , Issue.5 , pp. 735-743
    • Pierce, B.L.1
  • 32
    • 33846596193 scopus 로고    scopus 로고
    • Helgason A, Palsson S, Thorleifsson G, Grant SF, Emilsson V, Gunnarsdottir S et al.. 2007;39(2):218–25. This paper provides an eloquent example of how genetic association signals can be refined using pedigree-based data in a population isolate
    • Helgason A, Palsson S, Thorleifsson G, Grant SF, Emilsson V, Gunnarsdottir S et al. Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Genet. 2007;39(2):218–25. This paper provides an eloquent example of how genetic association signals can be refined using pedigree-based data in a population isolate.
    • Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Gene
  • 34
    • 77950909751 scopus 로고    scopus 로고
    • Patel AV et al. HNF1B and JAZF1 genes, diabetes, and prostate cancer risk
    • Stevens VL, Ahn J, Sun J, Jacobs EJ, Moore SC, Patel AV et al. HNF1B and JAZF1 genes, diabetes, and prostate cancer risk. Prostate. 2010;70(6):601–7.
    • (2010) Prostat , vol.70 , Issue.6 , pp. 601-607
    • Stevens, V.L.1    Ahn, J.2    Sun, J.3    Jacobs, E.J.4    Moore, S.C.5
  • 35
    • 34547625955 scopus 로고    scopus 로고
    • Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    • Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 2007;3(7):e115.
    • (2007) PLoS Gene , vol.3 , Issue.7 , pp. e115
    • Scuteri, A.1    Sanna, S.2    Chen, W.M.3    Uda, M.4    Albai, G.5    Strait, J.6
  • 38
    • 84883464230 scopus 로고    scopus 로고
    • Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications
    • Bonnefond A, Skrobek B, Lobbens S, Eury E, Thuillier D, Cauchi S et al. Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications. Nat Genet. 2013;45(9):1040–3.
    • (2013) Nat Gene , vol.45 , Issue.9 , pp. 1040-1043
    • Bonnefond, A.1    Skrobek, B.2    Lobbens, S.3    Eury, E.4    Thuillier, D.5    Cauchi, S.6
  • 39
    • 2442547553 scopus 로고    scopus 로고
    • Hallmans G, Agren A, Johansson G, Johansson A, Stegmayr B, Jansson JH et al. Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort - evaluation of risk factors and their interactions 2003;61:18–24. This paper describes the Northern Sweden Health and Disease Study, the collection of cohorts making up the Northern Sweden Biobank, within which the VIKING and GLACIER Studies are set
    • Hallmans G, Agren A, Johansson G, Johansson A, Stegmayr B, Jansson JH et al. Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort - evaluation of risk factors and their interactions. Scand J Public Health Suppl. 2003;61:18–24. This paper describes the Northern Sweden Health and Disease Study, the collection of cohorts making up the Northern Sweden Biobank, within which the VIKING and GLACIER Studies are set.
    • Scand J Public Health Supp
  • 40
    • 0034923930 scopus 로고    scopus 로고
    • Underreporting of energy intake in repeated 24-hour recalls related to gender, age, weight status, day of interview, educational level, reported food intake, smoking habits and area of living
    • Johansson G, Wikman A, Ahren AM, Hallmans G, Johansson I. Underreporting of energy intake in repeated 24-hour recalls related to gender, age, weight status, day of interview, educational level, reported food intake, smoking habits and area of living. Public Health Nutr. 2001;4(4):919–27.
    • (2001) Public Health Nut , vol.4 , Issue.4 , pp. 919-927
    • Johansson, G.1    Wikman, A.2    Ahren, A.M.3    Hallmans, G.4    Johansson, I.5
  • 41
    • 0036276513 scopus 로고    scopus 로고
    • Johansson I, Hallmans G, Wikman A, Biessy C, Riboli E, Kaaks R. . Public Health Nutr. 2002;5(3):487–96. This paper describes some of the dietary methods and available data in the GLACIER and VIKING Studies
    • Johansson I, Hallmans G, Wikman A, Biessy C, Riboli E, Kaaks R. Validation and calibration of food-frequency questionnaire measurements in the Northern Sweden Health and Disease cohort. Public Health Nutr. 2002;5(3):487–96. This paper describes some of the dietary methods and available data in the GLACIER and VIKING Studies.
    • Validation and calibration of food-frequency questionnaire measurements in the Northern Sweden Health and Disease cohor
  • 42
    • 0027787021 scopus 로고
    • Lissner L. "The Goteborg Quality of Life Instrument"–a psychometric evaluation of assessments of symptoms and well-being among women in a general population
    • Sullivan M, Karlsson J, Bengtsson C, Furunes B, Lapidus L, Lissner L. "The Goteborg Quality of Life Instrument"–a psychometric evaluation of assessments of symptoms and well-being among women in a general population. Scand J Prim Health Care. 1993;11(4):267–75.
    • (1993) Scand J Prim Health Car , vol.11 , Issue.4 , pp. 267-275
    • Sullivan, M.1    Karlsson, J.2    Bengtsson, C.3    Furunes, B.4    Lapidus, L.5
  • 45
    • 84958746637 scopus 로고    scopus 로고
    • AUDIT : the Alcohol Use Disorders Identification Test : guidelines for use in primary health care. 2nd ed
    • Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG, World Health Organization. Dept. of Mental Health and Substance Dependence. AUDIT: the Alcohol Use Disorders Identification Test: guidelines for use in primary health care. 2nd ed. Geneva: World Health Organization; 2001. 38 p.
    • Geneva: World Health Organizatio , vol.2001 , pp. 38
  • 46
    • 1342323612 scopus 로고    scopus 로고
    • The value of the CAGE in screening for alcohol abuse and alcohol dependence in general clinical populations: a diagnostic meta-analysis
    • COI: 1:STN:280:DC%2BD2c7ivVKrsw%3D%3D, PID: 15019008
    • Aertgeerts B, Buntinx F, Kester A. The value of the CAGE in screening for alcohol abuse and alcohol dependence in general clinical populations: a diagnostic meta-analysis. J Clin Epidemiol. 2004;57(1):30–9.
    • (2004) J Clin Epidemio , vol.57 , Issue.1 , pp. 30-39
    • Aertgeerts, B.1    Buntinx, F.2    Kester, A.3
  • 48
    • 36348942404 scopus 로고    scopus 로고
    • The genetic population structure of northern Sweden and its implications for mapping genetic diseases
    • Einarsdottir E, Egerbladh I, Beckman L, Holmberg D, Escher SA. The genetic population structure of northern Sweden and its implications for mapping genetic diseases. Hereditas. 2007;144(5):171–80.
    • (2007) Heredita , vol.144 , Issue.5 , pp. 171-180
    • Einarsdottir, E.1    Egerbladh, I.2    Beckman, L.3    Holmberg, D.4    Escher, S.A.5
  • 49
    • 85057646159 scopus 로고    scopus 로고
    • Longitudinal databases –sources for analyzing the life course: characteristics, difficulties and possibilities
    • Vikström P, Edvinsson S, Brändström A. Longitudinal databases –sources for analyzing the life course: characteristics, difficulties and possibilities. Hist Comput. 2004;14:1–2.
    • (2004) Hist Compu , vol.14 , pp. 1-2
    • Vikström, P.1    Edvinsson, S.2    Brändström, A.3
  • 51
    • 77958562031 scopus 로고    scopus 로고
    • Ngwa J et al.  Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies
    • Nettleton JA, McKeown NM, Kanoni S, Lemaitre RN, Hivert MF, Ngwa J et al. Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care. 2010;33(12):2684–91.
    • (2010) Diabetes Car , vol.33 , Issue.12 , pp. 2684-2691
    • Nettleton, J.A.1    McKeown, N.M.2    Kanoni, S.3    Lemaitre, R.N.4    Hivert, M.F.5
  • 52
    • 80052880822 scopus 로고    scopus 로고
    • Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis
    • Kanoni S, Nettleton JA, Hivert MF, Ye Z, van Rooij FJ, Shungin D et al. Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis. Diabetes. 2011;60(9):2407–16.
    • (2011) Diabete , vol.60 , Issue.9 , pp. 2407-2416
    • Kanoni, S.1    Nettleton, J.A.2    Hivert, M.F.3    Ye, Z.4    van Rooij, F.J.5    Shungin, D.6
  • 53
    • 84872232296 scopus 로고    scopus 로고
    • Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts
    • Nettleton JA, Hivert MF, Lemaitre RN, McKeown NM, Mozaffarian D, Tanaka T et al. Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. Am J Epidemiol. 2013;177(2):103–15.
    • (2013) Am J Epidemio , vol.177 , Issue.2 , pp. 103-115
    • Nettleton, J.A.1    Hivert, M.F.2    Lemaitre, R.N.3    McKeown, N.M.4    Mozaffarian, D.5    Tanaka, T.6
  • 54
    • 84874705274 scopus 로고    scopus 로고
    • Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies
    • Hruby A, Ngwa JS, Renstrom F, Wojczynski MK, Ganna A, Hallmans G et al. Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies. J Nutr. 2013;143(3):345–53.
    • (2013) J Nut , vol.143 , Issue.3 , pp. 345-353
    • Hruby, A.1    Ngwa, J.S.2    Renstrom, F.3    Wojczynski, M.K.4    Ganna, A.5    Hallmans, G.6
  • 55
    • 84860587659 scopus 로고    scopus 로고
    • No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels
    • Scott RA, Chu AY, Grarup N, Manning AK, Hivert MF, Shungin D et al. No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. Diabetes. 2012;61(5):1291–6.
    • (2012) Diabete , vol.61 , Issue.5 , pp. 1291-1296
    • Scott, R.A.1    Chu, A.Y.2    Grarup, N.3    Manning, A.K.4    Hivert, M.F.5    Shungin, D.6
  • 56
    • 84861614905 scopus 로고    scopus 로고
    • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
    • Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet. 2012;44(6):659–69.
    • (2012) Nat Gene , vol.44 , Issue.6 , pp. 659-669
    • Manning, A.K.1    Hivert, M.F.2    Scott, R.A.3    Grimsby, J.L.4    Bouatia-Naji, N.5    Chen, H.6
  • 58
    • 84880226799 scopus 로고    scopus 로고
    • Smoking status, snus use, and variation at the CHRNA5-CHRNA3-CHRNB4 locus in relation to obesity: the GLACIER study
    • Varga TV, Hallmans G, Hu FB, Renstrom F, Franks PW. Smoking status, snus use, and variation at the CHRNA5-CHRNA3-CHRNB4 locus in relation to obesity: the GLACIER study. Am J Epidemiol. 2013;178(1):31–7.
    • (2013) Am J Epidemio , vol.178 , Issue.1 , pp. 31-37
    • Varga, T.V.1    Hallmans, G.2    Hu, F.B.3    Renstrom, F.4    Franks, P.W.5
  • 59
    • 81455135676 scopus 로고    scopus 로고
    • Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index
    • Freathy RM, Kazeem GR, Morris RW, Johnson PC, Paternoster L, Ebrahim S et al. Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index. Int J Epidemiol. 2011;40(6):1617–28.
    • (2011) Int J Epidemio , vol.40 , Issue.6 , pp. 1617-1628
    • Freathy, R.M.1    Kazeem, G.R.2    Morris, R.W.3    Johnson, P.C.4    Paternoster, L.5    Ebrahim, S.6
  • 62
    • 84875922294 scopus 로고    scopus 로고
    • Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake
    • Tanaka T, Ngwa JS, van Rooij FJA, Zillikens MC, Wojczynski MK, Frazier-Wood AC et al. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Am J Clin Nutr. 2013;97(6):1395–402.
    • (2013) Am J Clin Nut , vol.97 , Issue.6 , pp. 1395-1402
    • Tanaka, T.1    Ngwa, J.S.2    van Rooij, F.J.A.3    Zillikens, M.C.4    Wojczynski, M.K.5    Frazier-Wood, A.C.6
  • 64
    • 84887058576 scopus 로고    scopus 로고
    • Common variants associated with plasma triglycerides and risk for coronary artery disease
    • Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet. 2013;45(11):1345–52.
    • (2013) Nat Gene , vol.45 , Issue.11 , pp. 1345-1352
    • Do, R.1    Willer, C.J.2    Schmidt, E.M.3    Sengupta, S.4    Gao, C.5    Peloso, G.M.6
  • 65
    • 84864845456 scopus 로고    scopus 로고
    • Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
    • Voight BF, Peloso GM, Orho-Melander M, Frikke-Schmidt R, Barbalic M, Jensen MK et al. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet. 2012;380(9841):572–80.
    • (2012) Lance , vol.380 , Issue.9841 , pp. 572-580
    • Voight, B.F.1    Peloso, G.M.2    Orho-Melander, M.3    Frikke-Schmidt, R.4    Barbalic, M.5    Jensen, M.K.6
  • 66
    • 84871969762 scopus 로고    scopus 로고
    • Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TLet al. Large-scale association analysis identifies new risk loci for coronary artery disease
    • Consortium CAD, Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 2013;45(1):25–33.
    • (2013) Nat Gene , vol.45 , Issue.1 , pp. 25-33
  • 67
    • 84903472554 scopus 로고    scopus 로고
    • Varga TV, Sonestedt E, Shungin D, Koivula RW, Hallmans G, Escher SA et al. . 2014;10(6):e1004388. This paper provides a detailed description of the GLACIER Study and reports data on the association of gene variants at 157 loci and long-term deteriorations in blood lipid concentrations in people from Northern Sweden
    • Varga TV, Sonestedt E, Shungin D, Koivula RW, Hallmans G, Escher SA et al. Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study. PLoS Genet. 2014;10(6):e1004388. This paper provides a detailed description of the GLACIER Study and reports data on the association of gene variants at 157 loci and long-term deteriorations in blood lipid concentrations in people from Northern Sweden.
    • Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study. PLoS Gene
  • 68
    • 39049146958 scopus 로고    scopus 로고
    • Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations
    • Franks PW, Rolandsson O, Debenham SL, Fawcett KA, Payne F, Dina C et al. Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations. Diabetologia. 2008;51(3):458–63.
    • (2008) Diabetologi , vol.51 , Issue.3 , pp. 458-463
    • Franks, P.W.1    Rolandsson, O.2    Debenham, S.L.3    Fawcett, K.A.4    Payne, F.5    Dina, C.6
  • 70
    • 77950358970 scopus 로고    scopus 로고
    • Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk
    • Fawcett KA, Wheeler E, Morris AP, Ricketts SL, Hallmans G, Rolandsson O et al. Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk. Diabetes. 2010;59(3):741–6.
    • (2010) Diabete , vol.59 , Issue.3 , pp. 741-746
    • Fawcett, K.A.1    Wheeler, E.2    Morris, A.P.3    Ricketts, S.L.4    Hallmans, G.5    Rolandsson, O.6
  • 71
    • 77958027965 scopus 로고    scopus 로고
    • Magic, Payne F, Hallmans Get al. Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population
    • Fontaine-Bisson B, Renstrom F, Rolandsson O, Magic, Payne F, Hallmans G et al. Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. Diabetologia. 2010;53(10):2155–62.
    • (2010) Diabetologi , vol.53 , Issue.10 , pp. 2155-2162
    • Fontaine-Bisson, B.1    Renstrom, F.2    Rolandsson, O.3
  • 72
    • 75749086085 scopus 로고    scopus 로고
    • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    • Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010;42(2):105–16.
    • (2010) Nat Gene , vol.42 , Issue.2 , pp. 105-116
    • Dupuis, J.1    Langenberg, C.2    Prokopenko, I.3    Saxena, R.4    Soranzo, N.5    Jackson, A.U.6
  • 73
    • 78751535877 scopus 로고    scopus 로고
    • Renstrom F, Shungin D, Johansson I, Investigators M, Florez JC, Hallmans G et al.. 2011;60(1):345–54. This paper provides a detailed description of the GLACIER Study and reports data on the association of gene variants at 16 loci and long-term deteriorations in blood glucose concentrations in people from Northern Sweden
    • Renstrom F, Shungin D, Johansson I, Investigators M, Florez JC, Hallmans G et al. Genetic predisposition to long-term nondiabetic deteriorations in glucose homeostasis: Ten-year follow-up of the GLACIER study. Diabetes. 2011;60(1):345–54. This paper provides a detailed description of the GLACIER Study and reports data on the association of gene variants at 16 loci and long-term deteriorations in blood glucose concentrations in people from Northern Sweden.
    • Genetic predisposition to long-term nondiabetic deteriorations in glucose homeostasis: Ten-year follow-up of the GLACIER study. Diabete
  • 74
    • 84876276050 scopus 로고    scopus 로고
    • Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
    • Albrechtsen A, Grarup N, Li Y, Sparso T, Tian G, Cao H et al. Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia. 2013;56(2):298–310.
    • (2013) Diabetologi , vol.56 , Issue.2 , pp. 298-310
    • Albrechtsen, A.1    Grarup, N.2    Li, Y.3    Sparso, T.4    Tian, G.5    Cao, H.6
  • 75
    • 64549158008 scopus 로고    scopus 로고
    • Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden
    • Renstrom F, Payne F, Nordstrom A, Brito EC, Rolandsson O, Hallmans G et al. Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden. Hum Mol Genet. 2009;18(8):1489–96.
    • (2009) Hum Mol Gene , vol.18 , Issue.8 , pp. 1489-1496
    • Renstrom, F.1    Payne, F.2    Nordstrom, A.3    Brito, E.C.4    Rolandsson, O.5    Hallmans, G.6
  • 76
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • Morris AP, Voight BF, Teslovich TM, Ferreira T, Segre AV, Steinthorsdottir V et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012;44(9):981–90.
    • (2012) Nat Gene , vol.44 , Issue.9 , pp. 981-990
    • Morris, A.P.1    Voight, B.F.2    Teslovich, T.M.3    Ferreira, T.4    Segre, A.V.5    Steinthorsdottir, V.6
  • 78
    • 84878594902 scopus 로고    scopus 로고
    • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
    • Berndt SI, Skibola CF, Joseph V, Camp NJ, Nieters A, Wang Z et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013;45(5):501–12.
    • (2013) Nat Gene , vol.45 , Issue.5 , pp. 501-512
    • Berndt, S.I.1    Skibola, C.F.2    Joseph, V.3    Camp, N.J.4    Nieters, A.5    Wang, Z.6
  • 80
    • 50449089222 scopus 로고    scopus 로고
    • Detection of sharing by descent, long-range phasing and haplotype imputation
    • Kong A, Masson G, Frigge ML, Gylfason A, Zusmanovich P, Thorleifsson G et al. Detection of sharing by descent, long-range phasing and haplotype imputation. Nat Genet. 2008;40(9):1068–75.
    • (2008) Nat Gene , vol.40 , Issue.9 , pp. 1068-1075
    • Kong, A.1    Masson, G.2    Frigge, M.L.3    Gylfason, A.4    Zusmanovich, P.5    Thorleifsson, G.6
  • 81
  • 82
    • 85057645474 scopus 로고    scopus 로고
    • From genetic discovery to future personalized health research, N Biotechnol:
    • Palotie A, Widen E, Ripatti S. From genetic discovery to future personalized health research. N Biotechnol, 2012.
    • (2012) Ripatti
    • Palotie, A.1    Widen, E.2
  • 83
    • 84892752841 scopus 로고    scopus 로고
    • Edwards A et al The architecture of parent-of-origin effects in mice
    • Mott R, Yuan W, Kaisaki P, Gan X, Cleak J, Edwards A et al. The architecture of parent-of-origin effects in mice. Cell. 2014;156(1–2):332–42.
    • (2014) Cel , vol.156 , Issue.1-2 , pp. 332-342
    • Mott, R.1    Yuan, W.2    Kaisaki, P.3    Gan, X.4    Cleak, J.5
  • 86
    • 2042437650 scopus 로고    scopus 로고
    • Consortium IHGS, Linton LM, Birren B, Nusbaum C, Zody MC et al. Initial sequencing and analysis of the human genome
    • Lander ES, Consortium IHGS, Linton LM, Birren B, Nusbaum C, Zody MC et al. Initial sequencing and analysis of the human genome. Nature. 2001;409(6822):860–921.
    • (2001) Natur , vol.409 , Issue.6822 , pp. 860-921
  • 88
    • 33845212250 scopus 로고    scopus 로고
    • Anticipating the 1,000 dollar genome
    • Mardis ER. Anticipating the 1,000 dollar genome. Genome Biol. 2006;7(7):112.
    • (2006) Genome Bio , vol.7 , Issue.7 , pp. 112
    • Mardis, E.R.1


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