-
3
-
-
56349096931
-
Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk
-
Lango H, Palmer CN, Morris AD et al (2008) Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. Diabetes 57:3129-3135
-
(2008)
Diabetes
, vol.57
, pp. 3129-3135
-
-
Lango, H.1
Palmer, C.N.2
Morris, A.D.3
-
4
-
-
55649105963
-
Clinical risk factors, DNA variants, and the development of type 2 diabetes
-
Lyssenko V, Jonsson A, Almgren P et al (2008) Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med 359:2220-2232
-
(2008)
N Engl J Med
, vol.359
, pp. 2220-2232
-
-
Lyssenko, V.1
Jonsson, A.2
Almgren, P.3
-
5
-
-
56749101779
-
Genotype score in addition to common risk factors for prediction of type 2 diabetes
-
Meigs JB, Shrader P, Sullivan LM et al (2008) Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med 359:2208-2219
-
(2008)
N Engl J Med
, vol.359
, pp. 2208-2219
-
-
Meigs, J.B.1
Shrader, P.2
Sullivan, L.M.3
-
6
-
-
64549158008
-
Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden
-
Renstrom F, Payne F, Nordstrom A et al (2009) Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden. Hum Mol Genet 18:1489-1496
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1489-1496
-
-
Renstrom, F.1
Payne, F.2
Nordstrom, A.3
-
7
-
-
39049146958
-
Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations
-
Franks PW, Rolandsson O, Debenham SL et al (2008) Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations. Diabetologia 51:458-463
-
(2008)
Diabetologia
, vol.51
, pp. 458-463
-
-
Franks, P.W.1
Rolandsson, O.2
Debenham, S.L.3
-
8
-
-
2442547553
-
Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort-evaluation of risk factors and their interactions
-
Hallmans G, Agren A, Johansson G et al (2003) Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort-evaluation of risk factors and their interactions. Scand J Public Health Suppl 61:18-24
-
(2003)
Scand J Public Health Suppl
, vol.61
, pp. 18-24
-
-
Hallmans, G.1
Agren, A.2
Johansson, G.3
-
9
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Willer CJ, Speliotes EK, Loos RJ et al (2009) Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 41:25-34
-
(2009)
Nat Genet
, vol.41
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.3
-
10
-
-
67651236725
-
Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution
-
Lindgren CM, Heid IM, Randall JC et al (2009) Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution. PLoS Genet 5:e1000508
-
(2009)
PLoS Genet
, vol.5
-
-
Lindgren, C.M.1
Heid, I.M.2
Randall, J.C.3
-
11
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
Dupuis J, Langenberg C, Prokopenko I et al (2010) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 42:105-116
-
(2010)
Nat Genet
, vol.42
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
-
12
-
-
42349106044
-
Meta-analysis of genome- wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
Zeggini E, Scott LJ, Saxena R et al (2008) Meta-analysis of genome- wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 40:638-645
-
(2008)
Nat Genet
, vol.40
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
-
13
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
Kathiresan S, Willer CJ, Peloso GM et al (2009) Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 41:56-65
-
(2009)
Nat Genet
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
Willer, C.J.2
Peloso, G.M.3
-
14
-
-
58149163141
-
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
-
Thorleifsson G, Walters GB, Gudbjartsson DF et al (2009) Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 41:18-24
-
(2009)
Nat Genet
, vol.41
, pp. 18-24
-
-
Thorleifsson, G.1
Walters, G.B.2
Gudbjartsson, D.F.3
-
15
-
-
48349113289
-
Common nonsynonymous variants in PCSK1 confer risk of obesity
-
Benzinou M, Creemers JW, Choquet H et al (2008) Common nonsynonymous variants in PCSK1 confer risk of obesity. Nat Genet 40:943-945
-
(2008)
Nat Genet
, vol.40
, pp. 943-945
-
-
Benzinou, M.1
Creemers, J.W.2
Choquet, H.3
-
16
-
-
0023710206
-
Comparing the areas under two or more correlated receiver operating characteristic curves: A nonparametric approach
-
DeLong ER, DeLong DM, Clarke-Pearson DL (1988) Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44:837-845
-
(1988)
Biometrics
, vol.44
, pp. 837-845
-
-
Delong, E.R.1
Delong, D.M.2
Clarke-Pearson, D.L.3
-
17
-
-
0035960122
-
Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
-
Fajans SS, Bell GI, Polonsky KS (2001) Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 345:971-980
-
(2001)
N Engl J Med
, vol.345
, pp. 971-980
-
-
Fajans, S.S.1
Bell, G.I.2
Polonsky, K.S.3
-
18
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393-403
-
(2002)
N Engl J Med
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
-
19
-
-
0035799806
-
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
-
DOI 10.1056/NEJM200105033441801
-
Tuomilehto J, Lindstrom J, Eriksson JG et al (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344:1343-1350 (Pubitemid 32378388)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.18
, pp. 1343-1350
-
-
Tuomilehto, J.1
Lindstrom, J.2
Eriksson, J.G.3
Valle, T.T.4
Hamalainen, H.5
Ianne-Parikka, P.6
Keinanen-Kiukaanniemi, S.7
Laakso, M.8
Louheranta, A.9
Rastas, M.10
Salminen, V.11
Uusitupa, M.12
-
20
-
-
50549202600
-
The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
-
Randle PJ, Garland PB, Hales CN, Newsholme EA (1963) The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1:785-789
-
(1963)
Lancet
, vol.1
, pp. 785-789
-
-
Randle, P.J.1
Garland, P.B.2
Hales, C.N.3
Newsholme, E.A.4
-
22
-
-
36849091421
-
Childhood predictors of young-onset type 2 diabetes
-
Franks PW, Hanson RL, Knowler WC et al (2007) Childhood predictors of young-onset type 2 diabetes. Diabetes 56:2964-2972
-
(2007)
Diabetes
, vol.56
, pp. 2964-2972
-
-
Franks, P.W.1
Hanson, R.L.2
Knowler, W.C.3
-
24
-
-
34249654186
-
Prediction of incident diabetes mellitus in middle-aged adults: The framingham offspring study
-
Wilson PW, Meigs JB, Sullivan L, Fox CS, Nathan DM, D'Agostino RB Sr (2007) Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study. Arch Intern Med 167:1068-1074
-
(2007)
Arch Intern Med
, vol.167
, pp. 1068-1074
-
-
Wilson, P.W.1
Meigs, J.B.2
Sullivan, L.3
Fox, C.S.4
Nathan, D.M.5
D'Agostino Sr., R.B.6
-
25
-
-
0344412888
-
Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: Haploinsufficiency is associated with reduced serum apolipoprotein M levels
-
Richer S, Shih DQ, Pearson ER et al (2003) Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels. Diabetes 52:2989-2995
-
(2003)
Diabetes
, vol.52
, pp. 2989-2995
-
-
Richer, S.1
Shih, D.Q.2
Pearson, E.R.3
-
26
-
-
0035122282
-
Beta-cell genes and diabetes: Molecular and clinical characterization of mutations in transcription factors
-
Frayling TM, Evans JC, Bulman MP et al (2001) Beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors. Diabetes 50(Suppl 1):S94-S100
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL.1
-
-
Frayling, T.M.1
Evans, J.C.2
Bulman, M.P.3
-
27
-
-
73449117605
-
Genetic determinants of circulating sphingolipid concentrations in European populations
-
Hicks AA, Pramstaller PP, Johansson A et al (2009) Genetic determinants of circulating sphingolipid concentrations in European populations. PLoS Genet 5:e1000672
-
(2009)
PLoS Genet
, vol.5
-
-
Hicks, A.A.1
Pramstaller, P.P.2
Johansson, A.3
-
28
-
-
70349980881
-
The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver
-
Beer NL, Tribble ND, McCulloch LJ et al (2009) The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver. Hum Mol Genet 18:4081-4088
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4081-4088
-
-
Beer, N.L.1
Tribble, N.D.2
McCulloch, L.J.3
-
29
-
-
54249088172
-
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations
-
Orho-Melander M, Melander O, Guiducci C et al (2008) Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes 57:3112-3121
-
(2008)
Diabetes
, vol.57
, pp. 3112-3121
-
-
Orho-Melander, M.1
Melander, O.2
Guiducci, C.3
-
30
-
-
50949132578
-
The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population
-
Vaxillaire M, Cavalcanti-Proenca C, Dechaume A et al (2008) The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population. Diabetes 57:2253-2257
-
(2008)
Diabetes
, vol.57
, pp. 2253-2257
-
-
Vaxillaire, M.1
Cavalcanti-Proenca, C.2
Dechaume, A.3
-
31
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J et al (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445:881-885
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
-
32
-
-
0028304329
-
The use of predicted confidence intervals when planning experiments and the misuse of power when interpreting results
-
Goodman SN, Berlin JA (1994) The use of predicted confidence intervals when planning experiments and the misuse of power when interpreting results. Ann Intern Med 121:200-206
-
(1994)
Ann Intern Med
, vol.121
, pp. 200-206
-
-
Goodman, S.N.1
Berlin, J.A.2
-
33
-
-
0026704913
-
Confidence limit analyses should replace power calculations in the interpretation of epidemiologic studies
-
Smith AH, Bates MN (1992) Confidence limit analyses should replace power calculations in the interpretation of epidemiologic studies. Epidemiology 3:449-452
-
(1992)
Epidemiology
, vol.3
, pp. 449-452
-
-
Smith, A.H.1
Bates, M.N.2
-
34
-
-
0021807406
-
When was a "negative" clinical trial big enough? How many patients you needed depends on what you found
-
Detsky AS, Sackett DL (1985) When was a "negative" clinical trial big enough? How many patients you needed depends on what you found. Arch Intern Med 145:709-712
-
(1985)
Arch Intern Med
, vol.145
, pp. 709-712
-
-
Detsky, A.S.1
Sackett, D.L.2
-
35
-
-
33847211808
-
TCF7L2 polymorphisms are associated with type 2 diabetes in northern Sweden
-
Mayans S, Lackovic K, Lindgren P et al (2007) TCF7L2 polymorphisms are associated with type 2 diabetes in northern Sweden. Eur J Hum Genet 15:342-346
-
(2007)
Eur J Hum Genet
, vol.15
, pp. 342-346
-
-
Mayans, S.1
Lackovic, K.2
Lindgren, P.3
|