Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

Nature

Volumn 497, Issue 7450, 2013, Pages 517-520

  Styrkarsdottir, Unnur ^a   Thorleifsson, Gudmar ^a   Sulem, Patrick ^a   Gudbjartsson, Daniel F ^a   Sigurdsson, Asgeir ^a   Jonasdottir, Aslaug ^a   Jonasdottir, Adalbjorg ^a   Oddsson, Asmundur ^a,b   Helgason, Agnar ^a   Magnusson, Olafur T ^a   Walters, G Bragi ^a   Frigge, Michael L ^a   Helgadottir, Hafdis T ^a   Johannsdottir, Hrefna ^a   Bergsteinsdottir, Kristin ^c   Ogmundsdottir, Margret H ^c   Center, Jacqueline R ^d,e,f   Nguyen, Tuan V ^d,f   Eisman, John A ^d,e,f,g   Christiansen, Claus ^h   Steingrimsson, Erikur ^c   Jonasson, Jon G ^c,i,j   Tryggvadottir, Laufey ^c,j   Eyjolfsson, Gudmundur I ^k   Theodors, Asgeir ⁱ   Jonsson, Thorvaldur ^c,i   Ingvarsson, Thorvaldur ^l,m   Olafsson, Isleifur ⁱ   Rafnar, Thorunn ^a   Kong, Augustine ^a   Sigurdsson, Gunnar ^a   Masson, Gisli ^c,i   Thorsteinsdottir, Unnur ^a,c   Stefansson, Kari ^a,c   more..

^a DECODE GENETICS   (Iceland)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF ICELAND   (Iceland)

^d GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e ST VINCENT S HOSPITAL   (Australia)

^f UNIVERSITY OF NEW SOUTH WALES   (Australia)

^g UNIVERSITY OF NOTRE DAME   (Australia)

^h CENTER FOR CLINICAL AND BASIC RESEARCH   (Denmark)

ⁱ LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^j ICELANDIC CANCER REGISTRY   (Iceland)

^k Laboratory in Mjodd (RAM)   (Iceland)

^l Akureyri Hospital   (Iceland)

^m UNIVERSITY OF AKUREYRI   (Iceland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

BONE; CANCER; GENE EXPRESSION; HEALTH RISK; MUTATION; OSTEOLOGY; PATHOLOGY; PUBLIC HEALTH; TESTOSTERONE;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; BILIARY TRACT CANCER; BIRTH WEIGHT; BONE DENSITY; BONE MINERALIZATION; BONE REMODELING; ELECTROLYTE DISTURBANCE; FRAGILITY FRACTURE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; HUMAN; LGR4 GENE; LOSS OF FUNCTION MUTATION; META ANALYSIS (TOPIC); NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; OSSIFICATION; PHENOTYPE; POSTMENOPAUSE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SKIN CARCINOMA; STOP CODON; WNT SIGNALING PATHWAY;

ANIMALS; AUSTRALIA; BILIARY TRACT NEOPLASMS; BONE DENSITY; CARCINOMA, SQUAMOUS CELL; CODON, NONSENSE; DENMARK; DOWN-REGULATION; FEMALE; HETEROZYGOTE; HUMANS; ICELAND; MALE; MENARCHE; MICE; MICE, KNOCKOUT; OSTEOPOROTIC FRACTURES; PHENOTYPE; RECEPTORS, G-PROTEIN-COUPLED; SKIN NEOPLASMS; TESTOSTERONE; WATER-ELECTROLYTE IMBALANCE;

ICELAND;

MUS;

EID: 84878143904     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12124     Document Type: Article

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