Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase

Diabetologia

Volumn 53, Issue 4, 2010, Pages 768-778

  Bourron, O ^a,b   Daval, M ^a,b   Hainault, I ^a,b   Hajduch, E ^a,b   Servant, J M ^c   Gautier, J F ^a,b,c   Ferre P ^a,b   Foufelle, F ^a,b  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

Adipocytes; AMP activated protein kinase; Atrial natriuretic peptide; Biguanides; Hormone sensitive lipase; Lipolysis; Non esterified fatty acids; Thiazolidinediones

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ATRIAL NATRIURETIC FACTOR; BIGUANIDE DERIVATIVE; FAT DROPLET; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; ISOPRENALINE;

ADIPOCYTE; ADIPOSE TISSUE; ADULT; ARTICLE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPOLYSIS; PRIORITY JOURNAL; WESTERN BLOTTING;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; ADIPOCYTES; ADIPOSE TISSUE; ADRENERGIC BETA-AGONISTS; ADULT; AMINO ACID SUBSTITUTION; AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; BARIATRIC SURGERY; BIGUANIDES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; FEMALE; HUMANS; INSULIN RESISTANCE; LIPOLYSIS; OVERWEIGHT; PATIENT SELECTION; RIBONUCLEOTIDES; SERINE; THIAZOLIDINEDIONES; THREONINE;

EID: 77949268951     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1639-6     Document Type: Article

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